公开(公告)号：WO2013101877A3

公开(公告)日：2015-06-18

申请号：PCT/US2012071722

申请日：2012-12-27

Applicant: UNIV IOWA STATE RES FOUND ,  YANG BING ,  LI TING ,  LIU BO

Inventor： YANG BING ,  LI TING ,  LIU BO

IPC: C12N15/82

CPC classification number: C12N15/8281 ,  C07K14/415 ,  C12N9/16

Abstract: Applicants have successfully generated heritable phenotypes in plants making them resistant to bacterial blight. TAL effector binding elements, (EBEs) of bacterial pathogen disease susceptibility genes are modified to prevent induction of expression associated with disease states caused by the bacterial pathogens. Surprisingly, Applicants have found that modifications may be made in the EBEs of these genes which prevent bacterial pathogen induction, but still allow for normal plant development and seed production. Nucleic acid sequences for generating such plants, amino acid sequences, cells, vectors and expression constructs are included as well as resistant plants, seeds and lines.

Abstract translation: 申请人已成功地在植物中产生了遗传表型，使其对细菌性枯萎病具有抗性。 细菌病原体易感性基因的TAL效应物结合元件（EBEs）被修饰以防止与由细菌病原体引起的疾病状态相关的表达的诱导。 令人惊讶的是，申请人已经发现可以在这些基因的EBE中进行修饰，这些基因预防细菌病原体的诱导，但仍然允许正常的植物发育和种子生产。 包括用于产生这种植物，氨基酸序列，细胞，载体和表达构建体的核酸序列以及抗性植物，种子和品系。

公开(公告)号：WO2013043638A1

公开(公告)日：2013-03-28

申请号：PCT/US2012/055980

申请日：2012-09-19

Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  YANG, Bing ,  LI, Ting ,  HUANG, Sheng

Inventor： YANG, Bing ,  LI, Ting ,  HUANG, Sheng

IPC: C12N15/87 ,  C12N15/82 ,  C12N15/85

CPC classification number: C12N15/905 ,  C07K2319/81 ,  C12N9/22 ,  C12N15/902 ,  C12N2800/80

Abstract: The present invention provides compositions and methods for targeted cleavage of cellular chromatin in a region of interest and/or homologous recombination at a predetermined site in cells. Compositions include fusion polypeptides comprising a TAL effector binding or a zinc finger domain and an I-TevI homing endonuclease cleavage domain as well as nucleic acid sequence encoding the same. The use of the I-TevI domain allows for monomer endonuclease sequences to achieve cleavage of cellular chromatin and represents an advantage over prior endonucleases which require self-dimerization, and two nucleases with appropriate spacers.

Abstract translation: 本发明提供了在细胞中的预定位点处目的切割感兴趣区域和/或同源重组中的细胞染色质的组合物和方法。 组合物包括包含TAL效应物结合或锌指结构域和I-TevI​​归巢内切核酸酶切割结构域的融合多肽以及编码该融合多肽的核酸序列。 使用I-TevI​​结构域允许单体内切核酸酶序列实现细胞染色质的切割，并且代表了优于需要自身二聚化的先前核酸内切酶的优点，以及具有合适间隔物的两个核酸酶。

公开(公告)号：WO2011028221A1

公开(公告)日：2011-03-10

申请号：PCT/US2010/001851

申请日：2010-06-28

Applicant: CREE, INC. ,  HEIKMAN, Sten ,  JACOB-MITOS, Matthew ,  LI, Ting ,  IBBETSON, James

Inventor： HEIKMAN, Sten ,  JACOB-MITOS, Matthew ,  LI, Ting ,  IBBETSON, James

IPC: H01L33/46

CPC classification number: H01L33/46 ,  H01L33/00 ,  H01L33/0062 ,  H01L33/387 ,  H01L33/405 ,  H01L33/60 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73265 ,  H01L2924/181 ,  H01L2924/00012 ,  H01L2924/00014

Abstract: A composite high reflectivity mirror (CHRM, 1102) with at least one smooth interior surface interface. The CHRM includes a composite portion, for example dielectric stack (1106) and reflective metal (1108), on a base element. At least one of the internal surfaces is polished to achieve a smooth interface. The polish can be performed (A) on the surface of the base element, on various layers (B, C) of the composite portion, or both. The resulting smooth interface (s) (A, B, C) reflect more of the incident light in an intended direction. The CHRMs may be integrated into light emitting diode (LED 1100) devices to increase optical output efficiency.

Abstract translation: 具有至少一个平滑内表面界面的复合高反射镜（CHRM，1102）。 CHRM在基底元件上包括复合部分，例如电介质堆叠（1106）和反射金属（1108）。 至少一个内表面被抛光以实现平滑的界面。 可以在基体表面上，在复合部分的各个层（B，C）上或两者上执行抛光（A）。 所得到的平滑界面（A，B，C）反射更多的预期方向的入射光。 CHRM可以集成到发光二极管（LED 1100）装置中以增加光输出效率。

公开(公告)号：WO2006062647A3

公开(公告)日：2008-11-20

申请号：PCT/US2005040257

申请日：2005-11-08

Applicant: NEUROME INC ,  LI TING-KAI ,  CARR LUCINDA G ,  ELLISON JULIE A ,  CHANG HWAI WEN ,  LO DAVID D

Inventor： LI TING-KAI ,  CARR LUCINDA G ,  ELLISON JULIE A ,  CHANG HWAI WEN ,  LO DAVID D

IPC: C12Q1/00 ,  A61K48/00 ,  C07H21/04 ,  C12N5/00

CPC classification number: C12Q1/6883 ,  A61K38/1709 ,  A61K48/00 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/6893 ,  G01N33/98 ,  G01N2800/307

Abstract: Polynucleotides, polypeptides, kits and methods are provided related to regulated genes characteristic of alcoholism

Abstract translation: 提供了与酒精中毒特征的调节基因相关的多核苷酸，多肽，试剂盒和方法

公开(公告)号：WO2013101877A2

公开(公告)日：2013-07-04

申请号：PCT/US2012/071722

申请日：2012-12-27

Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  YANG, Bing ,  LI, Ting ,  LIU, Bo

Inventor： YANG, Bing ,  LI, Ting ,  LIU, Bo

IPC: A01H5/00 ,  C12N15/82

CPC classification number: C12N15/8281 ,  C07K14/415 ,  C12N9/16

Abstract: Applicants have successfully generated heritable phenotypes in plants making them resistant to bacterial blight. TAL effector binding elements, (EBEs) of bacterial pathogen disease susceptibility genes are modified to prevent induction of expression associated with disease states caused by the bacterial pathogens. Surprisingly, Applicants have found that modifications may be made in the EBEs of these genes which prevent bacterial pathogen induction, but still allow for normal plant development and seed production. Nucleic acid sequences for generating such plants, amino acid sequences, cells, vectors and expression constructs are included as well as resistant plants, seeds and lines.

Abstract translation: 申请人已成功地在植物中产生了遗传表型，使其对细菌性枯萎病具有抗性。 细菌病原体易感性基因的TAL效应物结合元件（EBEs）被修饰以防止与由细菌病原体引起的疾病状态相关的表达的诱导。 令人惊讶的是，申请人已经发现可以在这些基因的EBE中进行修饰，这些基因预防细菌病原体的诱导，但仍然允许正常的植物发育和种子生产。 包括用于产生这种植物，氨基酸序列，细胞，载体和表达构建体的核酸序列以及抗性植物，种子和品系。

公开(公告)号：WO2011157168A3

公开(公告)日：2012-05-03

申请号：PCT/CN2011075273

申请日：2011-06-03

Applicant: HUAWEI TECH CO LTD ,  XIAO YUXIANG ,  LI TING ,  ZHU ERNI ,  LV JINSONG

Inventor： XIAO YUXIANG ,  LI TING ,  ZHU ERNI ,  LV JINSONG

IPC: H04B1/04

CPC classification number: H04B1/0475

Abstract: The present invention provides a method for transmitting a radio frequency (RF) signal and a base station device. The method includes: controlling energy of a first RF input signal of a power amplifier (PA), transmitting a first RF output signal, and coupling part of the first RF output signal and feeding it back to a predistortion system, so as to control the energy increase of a second RF input signal inputted to the PA according to a preset energy increment. The method can realize adjustment for the interModulation Distortion (IMD) component in the RF output signal outputted from the PA in an initial phase (that is a startup phase), thereby improving linearity of the PA in the initial phase.

Abstract translation: 本发明提供了一种用于发送射频（RF）信号和基站装置的方法。 该方法包括：控制功率放大器（PA）的第一RF输入信号的能量，发送第一RF输出信号，以及耦合第一RF输出信号的一部分并将其馈送回预失真系统，以便控制 根据预设的能量增量输入到PA的第二RF输入信号的能量增加。 该方法可以在初始阶段（即启动阶段）中实现从PA输出的RF输出信号中的调制失真（IMD）分量的调整，从而提高初始阶段的PA的线性度。

公开(公告)号：WO2006014996A3

公开(公告)日：2006-02-09

申请号：PCT/US2005/026558

申请日：2005-07-27

Applicant: CREE, INC. ,  RAFFETTO, Mark ,  BHARATHAN, Jayesh ,  HABERERN, Kevin ,  BERGMANN, Michael ,  EMERSON, David ,  IBBETSON, James ,  LI, Ting

Inventor： RAFFETTO, Mark ,  BHARATHAN, Jayesh ,  HABERERN, Kevin ,  BERGMANN, Michael ,  EMERSON, David ,  IBBETSON, James ,  LI, Ting

IPC: H01L33/00

Abstract: A semiconductor based Light Emitting Device (LED) can include a p-type nitride layer and a metal ohmic contact, on the p-type nitride layer. The metal ohmic contact can have an average thickness of less than about 25 A and a specific contact resistivity less than about 10 -3 ohm-cm 2 .

公开(公告)号：WO2014036871A1

公开(公告)日：2014-03-13

申请号：PCT/CN2013/080626

申请日：2013-08-01

Applicant: E. I. DU PONT DE NEMOURS AND COMPANY ,  KARAYIANNI, Eleni ,  LI, Ting ,  NI, Yong

Inventor： KARAYIANNI, Eleni ,  LI, Ting ,  NI, Yong

IPC: C08L67/02 ,  C08L51/04 ,  C08K5/16 ,  C08K5/5313 ,  H01B3/42

CPC classification number: C08L67/025 ,  C08K5/16 ,  C08K5/5313 ,  C08L51/04 ,  H01B3/421 ,  H01B3/427

Abstract: Disclosed herein is a fire-retardant copolyetherester composition comprising: (a) about 20-93.9 wt% of at least one copolyetherester; (b) about 5- 30 wt% of at least one halogen-free flame retardant; (c) about 0.1-20 wt% of at least one nitrogen-containing compound; and (d) about 1-30 wt% of at least one composite rubber-based graft copolymer. Further disclosed herein are articles comprising component parts formed of the fire-retardant copolyetherester composition.

Abstract translation: 本文公开了一种阻燃共聚醚酯组合物，其包含：（a）约20-93.9重量％的至少一种共聚醚酯; （b）约5-30wt％的至少一种不含卤素的阻燃剂; （c）约0.1-20重量％的至少一种含氮化合物; 和（d）约1-30重量％的至少一种复合橡胶基接枝共聚物。 本文进一步公开的是包含由阻燃共聚醚酯组合物形成的组分的物品。

公开(公告)号：WO2011159369A1

公开(公告)日：2011-12-22

申请号：PCT/US2011/024515

申请日：2011-02-11

Applicant: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. ,  YANG, Bing ,  LI, Ting ,  HUANG, Sheng

Inventor： YANG, Bing ,  LI, Ting ,  HUANG, Sheng

IPC: C12N15/62 ,  C07K19/00 ,  C12N15/52 ,  C12R1/64

CPC classification number: C12N9/22 ,  C12N15/8213

Abstract: The present invention provides compositions and methods for targeted cleavage of cellular chromatin in a region of interest and/or homologous recombination at a predetermined site in cells. Compositions include fusion polypeptides comprising a TAL effector binding domain and a cleavage domain. The cleavage domain can be from any endonuclease. In certain embodiments, the endonuclease is a Type IIS restriction endonuclease. In further embodiments, the Type IIS restriction endonuclease is Fokl.

Abstract translation: 本发明提供了在细胞中的预定位点处目的切割感兴趣区域和/或同源重组中的细胞染色质的组合物和方法。 组合物包括包含TAL效应子结合结构域和切割结构域的融合多肽。 切割结构域可以来自任何内切核酸酶。 在某些实施方案中，内切核酸酶是IIS型限制性内切酶。 在另外的实施方案中，类型IIS限制性内切核酸酶是Fok1。

公开(公告)号：WO2005034566A1

公开(公告)日：2005-04-14

申请号：PCT/US2004/030104

申请日：2004-09-13

Applicant: QUALCOMM INCORPORATED ,  SHI, Guangming, Carl ,  TORCHALSKI, Andrew ,  IYER, Rekha ,  TANGIRALA, Venkat ,  LI, Ting Mui

Inventor： SHI, Guangming, Carl ,  TORCHALSKI, Andrew ,  IYER, Rekha ,  TANGIRALA, Venkat ,  LI, Ting Mui

IPC: H04Q7/38

CPC classification number: H04W48/18 ,  H04L63/0853 ,  H04W4/90 ,  H04W48/02 ,  H04W72/00 ,  H04W76/50

Abstract: Systems and techniques are disclosed relating to communications. The systems and techniques include receiving an origination request for a call, determining whether the call is allowed on each of a plurality of wireless networks as a function of the origination request, and originating the call over a network selected from a plurality of networks. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or the meaning of the claims.

Abstract translation: 公开了与通信相关的系统和技术。 系统和技术包括接收呼叫的发起请求，根据发起请求确定是否允许多个无线网络中的每一个上的呼叫，以及通过从多个网络选择的网络发起呼叫。 要强调的是，该摘要被提供以符合要求摘要的规则，这将允许搜索者或其他读者快速确定技术公开的主题。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。