公开(公告)号：WO2005050180A1

公开(公告)日：2005-06-02

申请号：PCT/US2004/038599

申请日：2004-11-17

Applicant: GENERAL ELECTRIC COMPANY ,  JANSEN, Floribertus, Heukensfeldt ,  LORRAINE, Peter, William ,  LOMNES, Stephen, Johnson ,  FOMITCHOV, Pavel Alexeyevich

Inventor： JANSEN, Floribertus, Heukensfeldt ,  LORRAINE, Peter, William ,  LOMNES, Stephen, Johnson ,  FOMITCHOV, Pavel Alexeyevich

IPC: G01N21/47

CPC classification number: G01N21/6456 ,  A61B5/0051 ,  A61B5/0091 ,  A61B5/4312 ,  A61K49/0017 ,  A61K49/0032 ,  A61K49/0034 ,  B82Y5/00 ,  B82Y10/00 ,  B82Y20/00 ,  G01N21/1717 ,  G01N21/4795 ,  G01N2021/1729 ,  G01N2021/6439

Abstract: A method and system for localization of fluorescence (120) in a scattering medium (104) such as a biological tissue are provided. In comparison to other optical imaging techniques, this disclosure provides for improved spatial resolution, decreased computational time for reconstructions, and allows anatomical and functional imaging simultaneously. The method including the steps of illuminating the scattering medium with an excitation light (102) to excite the fluorescence; modulating a portion of the emitted light from the fluorescence within the scattering medium using an ultrasonically induced variation (108) of material properties of the scattering medium (104) such as the refractive index; detecting the modulated optional signal at a surface of the scattering medium; and reconstructing a spatial distribution of the fluorescence in the scattering medium from the detected signal.

Abstract translation: 提供了用于在诸如生物组织的散射介质（104）中定位荧光（120）的方法和系统。 与其他光学成像技术相比，本公开提供了改进的空间分辨率，减少了重建的计算时间，并且同时允许解剖和功能成像。 该方法包括以激发光（102）照射散射介质以激发荧光的步骤; 使用诸如折射率的散射介质（104）的材料性质的超声波诱导变化（108）来调制来自散射介质内的荧光的一部分发射光; 在散射介质的表面处检测调制的可选信号; 以及从所检测的信号重构散射介质中的荧光的空间分布。

公开(公告)号：WO2009073014A1

公开(公告)日：2009-06-11

申请号：PCT/US2007/025228

申请日：2007-12-06

Applicant: LOCKHEED MARTIN CORPORATION ,  LORRAINE, Peter, William ,  HOWARD, Donald, Robert ,  RINGERMACHER, Henry, Israel ,  DUBOIS, Marc ,  DRAKE, Peter, William

Inventor： LORRAINE, Peter, William ,  HOWARD, Donald, Robert ,  RINGERMACHER, Henry, Israel ,  DUBOIS, Marc ,  DRAKE, Peter, William

IPC: G01N21/17 ,  G01N21/88 ,  G01N25/72 ,  G01N29/24

CPC classification number: G01N21/1717 ,  G01N21/1702 ,  G01N21/718 ,  G01N21/8851 ,  G01N25/72 ,  G01N29/228 ,  G01N29/2418 ,  G01N2021/1706 ,  G01N2021/8472 ,  G01N2201/0697 ,  G01N2291/0231

Abstract: An inspection system (200) is provided to examine internal structures of a target material (216). This inspection system includes a generation laser (210), an ultrasonic detection system (220, 226, 228, 230), a thermal imaging system (234), and a processor/control module (232). The generation laser (210) produces a pulsed laser beam (212) that is operable to induce ultrasonic displacements and thermal transients at the target material (216). The ultrasonic detection system detects ultrasonic surface displacements at the target material (216). The thermal imaging system (234) detects thermal transients at the target material (216). The processor (232) analyzes both detected ultrasonic displacements and thermal imagery of the target material (216) to yield information about the target material's internal structure. The target material (216) preferably comprises composite material.

Abstract translation: 提供检查系统（200）以检查目标材料（216）的内部结构。 该检查系统包括生成激光器（210），超声波检测系统（220,226,228,230），热成像系统（234）和处理器/控制模块（232）。 产生激光器（210）产生脉冲激光束（212），其可操作以在目标材料（216）处诱导超声位移和热瞬变。 超声波检测系统检测目标材料（216）的超声表面位移。 热成像系统（234）检测目标材料（216）处的热瞬态。 处理器（232）分析检测到的超声波位移和目标材料（216）的热图像，以产生关于目标材料的内部结构的信息。 目标材料（216）优选包括复合材料。

公开(公告)号：WO2005066949A1

公开(公告)日：2005-07-21

申请号：PCT/US2004/039298

申请日：2004-11-22

Applicant: GENERAL ELECTRIC COMPANY (a New York Corporation) ,  LAWRENCE, Brian, Lee ,  BODEN, Eugene, Pauling ,  DUBOIS, Marc ,  CHAN, Kwok, Pong ,  TIAN, Peifang ,  LONGLEY, Kathryn, Lynn ,  FILKINS, Robert, John ,  LORRAINE, Peter, William

Inventor： LAWRENCE, Brian, Lee ,  BODEN, Eugene, Pauling ,  DUBOIS, Marc ,  CHAN, Kwok, Pong ,  TIAN, Peifang ,  LONGLEY, Kathryn, Lynn ,  FILKINS, Robert, John ,  LORRAINE, Peter, William

IPC: G11B7/24

CPC classification number: G11B7/2534 ,  G03H2001/0264 ,  G03H2001/2289 ,  G03H2260/53 ,  G03H2270/53 ,  G11B7/0065 ,  G11B7/246 ,  G11B7/2467 ,  G11B7/2533 ,  G11B7/2535 ,  G11B7/26 ,  G11C13/042

Abstract: Holographic storage media (60) including a substrate and a dye material capable of undergoing a photo-induced change are disclosed. Data may be written into the holographic storage media using light of one wavelength and read using light of a different wavelength.

Abstract translation: 公开了包括基底和能够经历光诱导变化的染料的全息存储介质（60）。 可以使用一种波长的光将数据写入全息存储介质，并使用不同波长的光读取。