摘要:
A method and system for localization of fluorescence (120) in a scattering medium (104) such as a biological tissue are provided. In comparison to other optical imaging techniques, this disclosure provides for improved spatial resolution, decreased computational time for reconstructions, and allows anatomical and functional imaging simultaneously. The method including the steps of illuminating the scattering medium with an excitation light (102) to excite the fluorescence; modulating a portion of the emitted light from the fluorescence within the scattering medium using an ultrasonically induced variation (108) of material properties of the scattering medium (104) such as the refractive index; detecting the modulated optional signal at a surface of the scattering medium; and reconstructing a spatial distribution of the fluorescence in the scattering medium from the detected signal.
摘要:
A chemical, biochemical or biological analysis system and method including: a surface acoustic wave (SAW) actuator (6) including a piezoelectric substrate (9) and at least one interdigital electrode (17) located on a working surface (11) of the piezoelectric substrate (9), the SAW actuator generating travelling SAWs in the working surface when an electrical signal is applied to the interdigital electrode; at least one reaction chamber (19) located on the working surface of the piezoelectric substrate; a light detector (16) for detecting luminescent, fluorescent or phosphorescent emissions within the reaction chamber; a reagent flow line (29) for providing a flow of reagent through the reaction chamber; a test sample supply line (29) for supplying a test sample to the reaction chamber; wherein the SAW actuator can generate travelling SAWs within the working surface to thereby induce chaotic micromixing, convective transport, concentration or combinations thereof of the test sample and the reagent contained within the reaction chamber.
摘要:
Methods, devices and apparatus for measuring expansion/contraction properties of a material are described. According to an embodiment a method comprises: providing a device, said device comprising a sample comprising said material, said sample comprising a first surface and a second surface, a first substrate and a second substrate connected to said first surface and to said second surface of said sample, respectively, a reflective material attached to said second substrate, and two electrical contacts each independently in contact with said sample; applying voltage to said sample using said electrical contacts; illuminating said reflective material using a light source, such that said illumination comprises light having known and controllable polarization; collecting light reflected off said reflective material; measuring amplitude and phase of an oscillating change in polarization of the reflected light; and extracting parameters related to expansion/contraction from said reflected light measurement, thus evaluating said expansion/contraction properties of said material.
摘要:
Procédé et système (1) d'imagerie acousto-optique d'une zone d'observation (3) d'un milieu (2). Le système comprend un dispositif d'acquisition (11) comportant un réseau de transducteurs (4) pour générer une pluralité d'ondes acoustiques non-focalisées, un dispositif d'émission lumineuse (8) pour émettre une onde lumineuse incidente et générer des ondes lumineuses marquées comportant une composante acousto-optique décalée en fréquence par les ondes acoustiques non-focalisées, et un détecteur (9) pour acquérir des signaux de mesure (S). Le système comporte en outre un dispositif de traitement (12) pour déterminer une intensité lumineuse (I) dans la zone d'observation (3) à partir des signaux de mesure (S).
摘要:
The present invention provides for sonication-assisted metal-enhanced fluorescence, luminescence, and/or chemiluminescence assay systems using low-intensity ultrasound waves to significantly reduce the assay time by increasing the kinetic movement of molecules within the system.
摘要:
A method for irradiating a medium includes irradiating the medium with an electromagnetic wave which is scattered in the medium and modulated in frequency at a position in the medium; obtaining information corresponding to an interference pattern generated by interference between the modulated electromagnetic wave and a reference wave; and generating a phase conjugate wave, based on the obtained information, which irradiates the medium.
摘要:
The present invention provides for sonication-assisted metal-enhanced fluorescence, luminescence, and/or chemiluminescence assay systems using low-intensity ultrasound waves to significantly reduce the assay time by increasing the kinetic movement of molecules within the system.
摘要:
PZT振動子(4)の表面(上面)に固定(接着)された測定対象の試料(3)の表面(上面)に、断続光を照射することによってPZT振動子(4)から発生した音響信号の振幅に基づいて、複合共鳴周波数f t を求め、求めた複合共鳴周波数f t の断続光がダイオードアレイ(1)から断続光が照射されるようにダイオードアレイ(1)の発光状態を制御するようにした。そして、求めた複合共鳴周波数f t を用いて、試料(3)の音速ν、ヤング率E、及び振動減衰率τ等の音波物性を求めるようにした。
摘要翻译:基于从PZT振荡器(4)产生的声信号的振幅,通过照射对象样本的表面(或上表面)来确定复合谐振频率(f ) (3)以间歇光固定(或粘附)到PZT振荡器(4)的表面(或上表面)。 对二极管阵列(1)的发光状态进行控制,使得可以从二极管阵列(1)发射确定的复合谐振频率的间歇光(f t sub>)。 复合共振频率(f >t)用于确定声波特性,例如样品(3)的声速(Ω),杨氏模量(E)和周期性阻尼因子(t) )。
摘要:
A stress measuring method comprising the external force applying step of applying an external force to a sample, the electron beam applying step of applying an electron beam to the sample, the spectrum step of spectrally separating light produced from the sample by the electron beam applying step to obtain spectrum, and the stress computing step of determining a stress from a spectrum shift between a sample spectrum obtained by applying an electron beam to the above sample and a stress application spectrum obtained by applying an electron beam to a sample kept in a stress-sustained condition by the above external force applying step.