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    OLIGOSACCHARIDE CONJUGATES AND METHODS OF USE
    2.
    发明申请
    OLIGOSACCHARIDE CONJUGATES AND METHODS OF USE 审中-公开
    寡糖混合物和使用方法

    公开(公告)号：WO2014170681A2

    公开(公告)日：2014-10-23

    申请号：PCT/GB2014051202

    申请日：2014-04-16

    Applicant: SEC DEP FOR ENVIRONMENT FOOD AND RURAL AFFAIRS ,  UNIV ALBERTA

    Inventor： MCGIVEN JOHN ,  BUNDLE DAVID ,  HOWELLS LAURENCE ,  GUIARD JULIE ,  NARAYANASWAMY VIJAYA GANESH

    IPC: G01N33/53

    CPC classification number: A61K47/549 ,  A61K47/4833 ,  A61K47/50 ,  A61K47/6415 ,  A61K47/646 ,  G01N33/53 ,  G01N33/5308 ,  G01N33/56911 ,  G01N2333/23 ,  G01N2400/00 ,  G01N2400/10

    Abstract: There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-α- pyranose and comprising at least one -(1-3)-link between adjacent 4,6-dideoxy-4-acylamido-α-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from -CH2OH, -H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.

    Abstract translation: 提供了在样品中检测抗M和/或抗A和/或抗C / Y抗体的存在的方法，所述方法包括使样品与根据本发明提供的诊断缀合物接触，包括 包含至少两个4,6-二脱氧-4-酰氨基-α-吡喃糖单元的寡糖，并且包含相邻的4,6-二脱氧-4-酰基氨基-α-吡喃糖之间的至少一个（1-3） - 连接 单元，其中吡喃糖中第5位的碳与R基团连接，其中R独立地选自-CH 2 OH，-H或具有至少一个C原子的烷基，寡糖共价连接至非 - 糖分子或表面。

    COMPOUNDS USEFUL IN IMAGING AND THERAPY
    4.
    发明申请
    COMPOUNDS USEFUL IN IMAGING AND THERAPY 审中-公开
    化合物可用于成像和治疗

    公开(公告)号：WO2011160216A3

    公开(公告)日：2012-02-16

    申请号：PCT/CA2011000751

    申请日：2011-06-27

    Applicant: UNIV ALBERTA ,  KUMAR PIYUSH ,  WIEBE LEONARD ,  MCEWAN ALEXANDER

    Inventor： KUMAR PIYUSH ,  WIEBE LEONARD ,  MCEWAN ALEXANDER

    IPC: C07H19/052 ,  A61K31/7056 ,  A61K49/00 ,  A61K51/00 ,  C08B37/00

    CPC classification number: C07H19/052 ,  A61K51/0453 ,  A61K51/0491 ,  C08B37/0057

    Abstract: Provided in the following specification are precursors or synthons that are useful for the synthesis of various arabinose-based chemical and radiochemical derivatives of nitroimidazole-containing azomycin arabinosides, such as radioiodinated l-a-D-( 5-deoxy-5-[I*]- iodoarabinofuranosyl)-2-nitroimidazole (*IAZA), and radiofluorinated l-a-D-( 5-deoxy-5-[18F]-iodoarabinofuranosyl)-2-nitroimidazole ( 18FAZA). Such compounds are useful in imaging, therapy, or radiotherapy. Further, various syntheses of said precursors/synthons and the incorporation of said precursors/synthons into kits is provided. The precursors/ synthons provided herein allow for an improved and facile manufacturing process for nitroimidazole-containing azomycin arabinosides.

    Abstract translation: 在以下说明书中提供了可用于合成基于阿拉伯糖的各种基于硝基咪唑的阿奇霉素的化学和放射化学衍生物的前体或合成子，例如放射性碘化的laD-（5-脱氧-5- [I *] - 碘代尿烷呋喃糖基） -2-硝基咪唑（* IAZA）和放射性氟化的LaD-（5-脱氧-5- [18 F] - 碘代阿拉伯呋喃糖基）-2-硝基咪唑（18FAZA）。 这些化合物可用于成像，治疗或放射治疗。 此外，提供所述前体/合成子的各种合成以及所述前体/合成子掺入试剂盒中。 本文提供的前体/合成物允许用于含有硝基咪唑的阿拉伯糖苷的改良且易于制造的方法。

    ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISMS AND HAPLOTYPES WITH FEED INTAKE AND FEED EFFICIENCY IN BEEF CATTLE
    5.
    发明申请
    ASSOCIATIONS OF SINGLE NUCLEOTIDE POLYMORPHISMS AND HAPLOTYPES WITH FEED INTAKE AND FEED EFFICIENCY IN BEEF CATTLE 审中-公开
    单核苷酸多态性与嗜酸性粒细胞与饲料摄入和饲料效率的关系

    公开(公告)号：WO2008084404A3

    公开(公告)日：2009-12-23

    申请号：PCT/IB2008000558

    申请日：2008-01-04

    Applicant: UNIV ALBERTA ,  MOORE STEPHEN STEWART ,  SHERMAN ESTHER LAURA ,  NKRUMAH JOSHUA DONALD

    Inventor： MOORE STEPHEN STEWART ,  SHERMAN ESTHER LAURA ,  NKRUMAH JOSHUA DONALD

    IPC: G01N33/48 ,  G01N33/50

    CPC classification number: C12Q1/6888 ,  C12Q2600/156 ,  G06Q10/063 ,  G06Q10/0639

    Abstract: The physiological regulation of intake, growth and energy partitioning in animals is under the control of multiple genes, which may be important candidates for unraveling the genetic variation in economically relevant traits in beef production. The present invention relates to the identification of single nucleotide polymorphisms (SNPs) and their haplotypes, across the bovine genome in genes encoding polypeptides associated with feed efficiency, and their associations with residual feed intake in beef production. The invention further encompasses methods and systems, including network-based processes, to manage the SNP data, haplotype data and other data relating to specific animals and herds of animals, veterinarian care, diagnostic and quality control data and management of livestock which, based on genotyping, have predictable meat quality traits, husbandry conditions, animal welfare, food safety information, audit of existing processes and data from field locations.

    Abstract translation: 动物的摄入，生长和能量分配的生理调节受多种基因的控制，这可能是解决牛肉生产中经济相关性状遗传变异的重要候选物。 本发明涉及在编码与饲料效率相关的多肽的基因中的牛基因组中识别单核苷酸多态性（SNP）及其单倍型，以及它们与牛肉生产中残留饲料摄入的关系。 本发明还包括方法和系统，包括基于网络的过程，用于管理SNP数据，单倍型数据和与特定动物和动物群有关的其他数据，兽医护理，诊断和质量控制数据以及牲畜的管理，其基于 基因分型，具有可预测的肉质特征，畜牧条件，动物福利，食品安全信息，对现场流程和现场数据的审计。

    PREPARATION OF IRON OR IRON OXIDE NANOPARTICLES
    6.
    发明申请
    PREPARATION OF IRON OR IRON OXIDE NANOPARTICLES 审中-公开
    铁或氧化镍纳米粒子的制备

    公开(公告)号：WO2008073925A3

    公开(公告)日：2008-08-28

    申请号：PCT/US2007087045

    申请日：2007-12-11

    Applicant: HONDA MOTOR CO LTD ,  UNIV ALBERTA ,  BROOKS CHRISTOPHER J ,  VEINOT JONATHAN ,  MACDONALD JANET ,  RUSSELL VICTORIA

    Inventor： BROOKS CHRISTOPHER J ,  VEINOT JONATHAN ,  MACDONALD JANET ,  RUSSELL VICTORIA

    IPC: C01G49/00 ,  C01G49/06 ,  C01G49/08

    CPC classification number: C01G49/08 ,  B22F1/0018 ,  B22F9/305 ,  B82Y30/00 ,  C01G49/06 ,  C01P2002/01 ,  C01P2004/04 ,  C01P2004/64

    Abstract: The present teachings are directed towards a thermolysis method of producing iron- containing nanoparticles by providing an iron-containing component, a colloid stabilizing component, and an amount of water. The iron-containing component, the colloid stabilizing component, and the amount of water form a mixture, which is then heated to a temperature sufficient to form iron-containing nanoparticles, which are then isolated from the mixture. Another method is also provided which involves a repetitive shell growth method of producing iron-containing nanoparticles by providing a first amount of an iron-containing component and a colloid stabilizing component; the iron-containing component and the colloid stabilizing component are then mixed and heated to a temperature sufficient to form iron-containing nanoparticles. The mixture is allowed to cool to room temperature, and an additional amount of iron-containing component is added to the mixture, which is then reheated to reaction temperature, and the process is repeated until the isolated iron-containing nanoparticles obtain the desired size.

    Abstract translation: 本教导涉及通过提供含铁组分，胶体稳定组分和一定量的水来生产含铁纳米颗粒的热解方法。 含铁组分，胶体稳定组分和水的量形成混合物，然后将其加热到足以形成含铁纳米颗粒的温度，然后将其从混合物中分离出来。 还提供了另一种方法，其涉及通过提供第一量的含铁组分和胶体稳定组分来生产含铁纳米颗粒的重复壳生长方法; 然后将含铁组分和胶体稳定组分混合并加热到足以形成含铁纳米颗粒的温度。 将混合物冷却至室温，并向混合物中加入额外量的含铁组分，然后将其再加热至反应温度，并重复该过程直至分离的含铁纳米颗粒获得所需尺寸。

    NON-DATA-AIDED CHANNEL ESTIMATORS FOR MULTIPATH AND MULTIPLE ANTENNA WIRELESS SYSTEMS
    7.
    发明申请
    NON-DATA-AIDED CHANNEL ESTIMATORS FOR MULTIPATH AND MULTIPLE ANTENNA WIRELESS SYSTEMS 审中-公开
    非数据辅助信道估计器，用于多路天线和多天线无线系统

    公开(公告)号：WO2007101338A8

    公开(公告)日：2008-01-17

    申请号：PCT/CA2007000356

    申请日：2007-03-07

    Applicant: UNIV ALBERTA ,  BEAULIEU NORMAN C ,  CHEN YUNFEI

    Inventor： BEAULIEU NORMAN C ,  CHEN YUNFEI

    IPC: H04B17/00 ,  H04B7/005 ,  H04B15/00 ,  H04L1/00 ,  H04L27/14

    CPC classification number: H04L25/03197 ,  H04B1/71637 ,  H04L25/03292

    Abstract: Novel non-data-aided maximum likelihood estimators for the delays and the attenuations in an ultra-wide bandwidth channel are proposed. Numerical results show that these new estimators outperform the previous non-data-aided maximum likelihood channel estimators derived in the literature. Moreover, in some cases, the performances of the new non-data-aided estimators approach those of the data-aided estimators, enabling us to reduce the overhead expense of pilot symbols.

    Abstract translation: 提出了用于超宽带宽信道中的延迟和衰减的新型非数据辅助最大似然估计器。 数值结果表明，这些新的估计值优于文献中推导的以前的非数据辅助最大似然信道估计。 此外，在某些情况下，新的非数据辅助估计器的性能接近数据辅助估计器的性能，使我们能够减少导频符号的间接费用。

    GRAIN FRACTIONATION METHODS AND PRODUCTS
    10.
    发明申请
    GRAIN FRACTIONATION METHODS AND PRODUCTS 审中-公开
    谷物分解方法和产品

    公开(公告)号：WO0227011A3

    公开(公告)日：2003-10-02

    申请号：PCT/CA0101358

    申请日：2001-09-26

    Applicant: UNIV ALBERTA ,  VASANTHAN THAVA ,  TEMELLI FERAL

    Inventor： VASANTHAN THAVA ,  TEMELLI FERAL

    IPC: A23L7/10 ,  A61K8/60 ,  A61K8/73 ,  A61K31/716 ,  A61K36/899 ,  C08B37/00 ,  C12P19/04 ,  C12P19/14

    CPC classification number: C08B37/0024 ,  C12P19/04 ,  C12P19/14

    Abstract: The invention generally relates to a method for fractionating plant material into valuable components including beta-glucan. The method uses an organic solvent and water instead of water alone, acidified water and/or aqueous alkali as a solvent for the slurrying of a grain flour. In addition to concentrating beta-glucan, other product fractions produced by the method include starch concentrate, and organic solvent solubles. If enzyme treatments are used, other product fractions include dextrin, protein hydrolysates and organic solvent solubles. The process is particularly effective in concentrating beta-glucans in a state close to its native form from the endosperm of barley and oat grains.

    Abstract translation: 本发明一般涉及一种将植物材料分馏成有价值成分的方法，包括β-葡聚糖。 该方法使用有机溶剂和水代替单独的水，酸化水和/或碱水溶液作为谷物粉浆料的溶剂。 除了浓缩β-葡聚糖之外，通过该方法生产的其它产物级分还包括淀粉浓缩物和有机溶剂可溶物。 如果使用酶处理，其他产品级分包括糊精，蛋白质水解物和有机溶剂可溶物。 该方法在将β-葡聚糖浓缩成接近其天然形式的状态下从大麦和燕麦颗粒的胚乳中特别有效。

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