摘要:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a tetrazolyl-piperidinyl-benzoimidazole structure: Structure (I) which function as inhibitors influenza polymerase activity, and their use as therapeutics for the treatment of influenza.
摘要:
The invention relates to compounds and pharmaceutical compositions for use in treating malaria infections. The invention also relates to uses and methods of treating a malaria infection in a subject using the compounds and pharmaceutical compositions described. The invention further relates to methods of preparing the compounds described herein from plant material of Warburgia salutaris .
摘要:
The present invention provides compositions and methods for inhibiting PTPN22 for restoring human central B-cell tolerance or for treating or preventing an autoimmune disease or disorder.
摘要:
Provided herein are methods for treating, reducing or preventing influenza A virus infection in a patient, as well as compositions and articles of manufacture for treating, reducing or preventing influenza A virus infection in a patient.
摘要:
Compositions and methods for inhibiting, treating, and/or preventing fatty acid metabolism disorders, particularly fatty acid oxidation disorders, in a subject are provided.
摘要:
Die Erfindung betrifft eine Kombination zur Anwendung bei der Behandlung von immunmediierten chronischen Entzündungserkrankungen und Autoimmunerkrankungen aus C 3-8 -Carbonsäuren, deren physiologisch vertretbaren Salzen und/oder deren Estern einerseits und einen oder mehreren Fumarsäureestern und/oder deren Salzen andererseits sowie deren Verwendung bei der Behandlung von Psoriasis und Multipler Sklerose.
摘要:
본 발명은 (a) 탁산 4 내지 40 중량%, (b) 미디움 체인 트리글리세라이드 10 내지 30 중량%, (c) 모노올레일 글리세롤 30 내지 70 중량%, (d) 계면활성제 5 내지 30 중량%, 및 (e) 폴리옥실 글리세릴 지방산 에스테르 10 내지 30 중량%를 포함하는 경구 투여용 약학 조성물 및 이의 제조방법을 제공한다.
摘要:
본 발명의 오셀타미비르 유사체 및 상기 유사체가 결합된 나노입자는 오셀타미비르 저항성 인플루엔자 바이러스에 강하게 결합하므로, 이를 이용하여 오셀타미비르 저항성 인플루엔자 바이러스를 육안으로 빠르고 편리하게 검출할 수 있다. 따라서 신속하게 인플루엔자 바이러스에 감염된 환자의 치료 계획을 세우는데 유용하게 활용될 수 있다.