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    LASER BASED PROJECTION DISPLAY SYSTEM
    1.
    发明申请
    LASER BASED PROJECTION DISPLAY SYSTEM 审中-公开
    基于激光的投影显示系统

    公开(公告)号：WO2012151262A3

    公开(公告)日：2013-01-03

    申请号：PCT/US2012036096

    申请日：2012-05-02

    Applicant: UNIV CITY NEW YORK RES FOUND ,  MADAMOPOULOS NICHOLAS ,  PAPAGEORGIOU FOTINI

    Inventor： MADAMOPOULOS NICHOLAS ,  PAPAGEORGIOU FOTINI

    IPC: G03B21/14

    CPC classification number: H04N9/3129 ,  G03B21/2033 ,  G03B21/208 ,  H04N9/315 ,  H04N9/3161 ,  H04N9/3164

    Abstract: A laser projection system including one or more pluralities of laser sources, each plurality of laser sources emitting light having substantially a different predetermined wavelength in the visible range, a fiber optic laser beam combiner combining outputs of at least one of the pluralities of laser sources into one optical fiber, a fiber-optic delivery component coupled to the one optical fiber and one or more spatial light modulators, and one or more homogenizing optical elements, and one or more optical lens system for projecting the associated images on a screen.

    Abstract translation: 一种激光投影系统，包括一个或多个激光源，每个激光源发射在可见光范围内具有基本上不同的预定波长的光;光纤激光束组合器，其将多个激光源中的至少一个的输出组合成 一个光纤，耦合到一个光纤的光纤传送部件和一个或多个空间光调制器，以及一个或多个均质光学元件，以及用于将相关联的图像投影在屏幕上的一个或多个光学透镜系统。

    ELECTRODE ASSEMBLY
    3.
    发明申请
    ELECTRODE ASSEMBLY 审中-公开
    电极组件

    公开(公告)号：WO2012054587A3

    公开(公告)日：2012-08-16

    申请号：PCT/US2011056863

    申请日：2011-10-19

    Applicant: UNIV CITY NEW YORK RES FOUND ,  BIKSON MAROM ,  KRONBERG GREGORY ,  NAGUIB TAMER N ,  ARCE DENIS ,  MINHAS PREET

    Inventor： BIKSON MAROM ,  KRONBERG GREGORY ,  NAGUIB TAMER N ,  ARCE DENIS ,  MINHAS PREET

    IPC: A61N1/36 ,  A61N1/04 ,  A61N1/18

    CPC classification number: A61N1/0526 ,  A61N1/0456 ,  A61N1/0472 ,  A61N1/36025

    Abstract: An electrode assembly includes a substantially porous element configured to be coupled to an electrode for delivery of electrical current to a patient in a neurostimulation procedure. The substantially porous material defining a contact surface, of which at least a portion contacts the patient during the neurostimulation procedure. A first insulating member is coupled to the substantially porous element and exposed at the contact surface to prevent a portion of the contact surface from contacting the patient to deliver the electrical current during the neurostimulation procedure.

    Abstract translation: 电极组件包括基本上多孔的元件，其被配置为耦合到电极，用于在神经刺激过程中将电流传送到患者。 限定接触表面的基本上多孔的材料，其在神经刺激过程期间至少部分接触患者。 第一绝缘构件联接到基本上多孔的元件并在接触表面处暴露，以防止接触表面的一部分接触患者以在神经刺激过程期间传递电流。

    ACTIVITY ENHANCING CURCUMIN COMPOSITIONS AND METHODS OF USE
    5.
    发明申请
    ACTIVITY ENHANCING CURCUMIN COMPOSITIONS AND METHODS OF USE 审中-公开
    活性增强凝灰质组合物和使用方法

    公开(公告)号：WO2015081319A3

    公开(公告)日：2015-11-19

    申请号：PCT/US2014067819

    申请日：2014-11-28

    Applicant: UNIV CITY NEW YORK RES FOUND ,  THE FEINSTEIN INST MEDICAL RES

    Inventor： BANERJEE PROBAL ,  CASTELLANOS MARIO R ,  DEBATA PRIYA RANJAN ,  SZERSZEN ANITA ,  FATA JIMMIE E

    IPC: A61K36/00

    CPC classification number: A61K31/121 ,  A61K9/0034 ,  A61K9/0036 ,  A61K9/0056 ,  A61K9/06 ,  A61K9/127 ,  A61K31/05 ,  A61K31/12 ,  A61K31/353 ,  A61K2300/00

    Abstract: The present invention provides for compositions or formulations including a curcuminoid and at least one of resveratrol, resveratrol derivative, catechin, or catechin derivative. The present invention also provides for a method of treating any disease where uncontrolled cellular proliferation occurs, such as cancers. In particular, the present invention provides a method for treating cervical cancer and precancerous cervical lesions. The present invention also provides methods to treat viral infections. The disclosed compositions or formulations are biologically more active demonstrating strong synergy, functions to activate multiple novel genes. The disclosure further shows that the composition increases cellular uptake of curcumin and are able to stabilize curcumin in an aqueous environment. All these enhanced properties are accomplished by a composition or formulation that is much simpler to manufacture and lower in cost.

    Abstract translation: 本发明提供包含姜黄素和白藜芦醇，白藜芦醇衍生物，儿茶素或儿茶素衍生物中的至少一种的组合物或制剂。 本发明还提供了治疗任何不受控制的细胞增殖发生的疾病如癌症的方法。 特别地，本发明提供了治疗子宫颈癌和癌前期宫颈病变的方法。 本发明还提供了治疗病毒感染的方法。 所公开的组合物或制剂在生物学上更有活性，表现出强的协同作用，以激活多种新型基因的功能。 本发明进一步表明该组合物增加了姜黄素的细胞摄取并且能够在水性环境中稳定姜黄素。 所有这些增强的性能通过组合物或制剂来实现，其制造要简单得多，成本降低。

    CELLS AND METHODS FOR PRODUCING LUTEIN
    6.
    发明申请
    CELLS AND METHODS FOR PRODUCING LUTEIN 审中-公开
    用于生产罗廷辛的细胞和方法

    公开(公告)号：WO2013119552A3

    公开(公告)日：2015-06-18

    申请号：PCT/US2013024746

    申请日：2013-02-05

    Applicant: UNIV CITY NEW YORK RES FOUND

    Inventor： WURTZEL ELEANORE T ,  QUINLAN RENA

    IPC: C07C49/00 ,  C07C35/21 ,  C12P23/00

    CPC classification number: C12P23/00 ,  A23L33/135 ,  A23L33/145 ,  C07C403/24 ,  C12N9/001 ,  C12N9/0073 ,  C12N9/0083 ,  C12N9/1085 ,  C12N9/90 ,  C12Y103/05006 ,  C12Y114/13129 ,  C12Y114/99045 ,  C12Y205/01029 ,  C12Y205/01032 ,  C12Y505/01018 ,  C12Y505/01019

    Abstract: Provided herein are recombinant cells (e.g., recombinant bacteria or plant, insect, mammalian, and yeast cells) containing a nucleic acid encoding a CYP97A protein or a nucleic acid encoding a CYP97B protein; a nucleic acid encoding a CYP97C protein; a nucleic acid encoding a geranylgeranyl pyrophosphate synthase protein; a nucleic acid encoding a phytoene synthase protein; a nucleic acid encoding a phytoene desaturase protein; a nucleic acid encoding a lycopene β-cyclase protein; and a nucleic acid encoding a lycopene ε-cyclase protein. Also provided are methods of producing lutein that include culturing these recombinant cells (e.g., recombinant bacteria and yeast cells), and methods of generating these recombinant cells (e.g., recombinant bacteria and yeast cells). Also provided is lutein produced by these methods, and pharmaceutical compositions, food supplements, food products, and cosmetic compositions that contain lutein produced by these methods.

    Abstract translation: 本文提供了含有编码CYP97A蛋白的核酸或编码CYP97B蛋白的核酸的重组细胞（例如重组细菌或植物，昆虫，哺乳动物和酵母细胞） 编码CYP97C蛋白质的核酸; 编码香叶基香叶基焦磷酸合酶蛋白的核酸; 编码芸苔属合酶蛋白的核酸; 编码八氢番茄红素去饱和酶蛋白的核酸; 编码番茄红素β-环蛋白的核酸; 和编码番茄红素ε-环化酶蛋白质的核酸。 还提供了生产包括培养这些重组细胞（例如重组细菌和酵母细胞）的叶黄素的方法以及产生这些重组细胞（例如重组细菌和酵母细胞）的方法。 还提供了通过这些方法生产的叶黄素，以及含有通过这些方法生产的叶黄素的药物组合物，食品添加剂，食品和化妆品组合物。

    NO- AND H2S- RELEASING COMPOUNDS
    7.
    发明申请
    NO- AND H2S- RELEASING COMPOUNDS 审中-公开
    NO-和H2S-释放化合物

    公开(公告)号：WO2013025790A3

    公开(公告)日：2013-05-10

    申请号：PCT/US2012050922

    申请日：2012-08-15

    Applicant: UNIV CITY NEW YORK RES FOUND ,  KASHFI KHOSROW ,  KODELA RAVINDER

    Inventor： KASHFI KHOSROW ,  KODELA RAVINDER

    IPC: A61K31/13 ,  A01N33/24

    CPC classification number: C07C203/04 ,  A61K31/655 ,  C07C327/48 ,  C07C331/28 ,  C07D271/08 ,  C07D339/04 ,  C07D413/12 ,  C07F9/65583 ,  C07F9/6578

    Abstract: This disclosure relates to novel compounds containing an H2S releasing moiety and a nitric oxide (NO) releasing moiety covalently linked with a core (e.g., a salicylic acid moiety) and the use of such compounds in treating inflammatory diseases, including cancers. Therapeutic potency of these compounds is significantly higher than NSAIDs containing a H2S-releasing moiety alone (HS-NSAIDs) and NSAID containing a NO-releasing moiety alone (NO-NSAIDs). The compounds, in addition, exhibit reduced side effect, e.g., reduced stomach ulcers, upon administration.

    Abstract translation: 本公开涉及含有H 2 S释放部分和与核心（例如水杨酸部分）共价连接的一氧化氮（NO）释放部分的新化合物以及这些化合物在治疗包括癌症的炎性疾病中的用途。 这些化合物的治疗效力明显高于单独含有H 2 S释放部分（HS-NSAIDs）和含有NO释放部分（NO-NSAIDs）的NSAID的NSAID。 此外，化合物在施用时表现出减少的副作用，例如胃溃疡减少。

    CHARGE-ENHANCED NEURAL ELECTRIC STIMULATION SYSTEM
    9.
    发明申请
    CHARGE-ENHANCED NEURAL ELECTRIC STIMULATION SYSTEM 审中-公开
    电荷增强神经电刺激系统

    公开(公告)号：WO2011119251A2

    公开(公告)日：2011-09-29

    申请号：PCT/US2011022283

    申请日：2011-01-24

    Applicant: UNIV CITY NEW YORK RES FOUND ,  AHMED ZAGHLOUL ,  WIERASZKO ANDRZEJ

    Inventor： AHMED ZAGHLOUL ,  WIERASZKO ANDRZEJ

    IPC: A61N1/36 ,  A61N1/04 ,  A61N1/362

    CPC classification number: A61N1/36017 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/36103 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/36178

    Abstract: A system and method to treat neural communication impairment is provided. The neural communication impairment is present in a neural pathway, which can be a cortico-neuromuscular pathway, an intra-brain neural pathway, or in a sensory-cortico pathway. A synchronized external stimulation is applied to a first point in proximity to a first neural component at one end of the neural pathway and to a second point in proximity to a second neural component at the other end of the neural pathway. Two induced neural handshake signals contemporaneously arrive at a neural communication impairment point in the neural pathway, triggering and stimulating a rehabilitation process by which the neural connection is permanently improved. The synchronized applied electrical signals applied to the first and second points may have an opposite polarity in dipolar neural stimulation, or may have identical polarity and waveform in in-phase neural stimulation.

    Abstract translation: 提供了治疗神经沟通障碍的系统和方法。 神经沟通障碍存在于神经通路中，所述神经通路可以是皮质 - 神经肌肉通路，脑内神经通路或感觉 - 皮质通路。 同步的外部刺激被施加到靠近神经通路一端的第一神经元件的第一点和靠近神经通路另一端的第二神经元件的第二点。 两个诱发的神经握手信号同时到达神经通路中的神经沟通障碍点，触发并刺激恢复过程，通过该过程永久改善神经连接。 施加到第一和第二点的同步施加的电信号在偶极神经刺激中可以具有相反的极性，或者可以在同相神经刺激中具有相同的极性和波形。

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