公开(公告)号：WO2015134336A2

公开(公告)日：2015-09-11

申请号：PCT/US2015/018192

申请日：2015-02-27

Applicant: DREXEL UNIVERSITY ,  COHEN, Andrew ,  DION, Genevieve ,  WINTER, Mark ,  WAIT, Eric ,  KOERNER, Michael

Inventor： COHEN, Andrew ,  DION, Genevieve ,  WINTER, Mark ,  WAIT, Eric ,  KOERNER, Michael

IPC: A61F2/30

CPC classification number: G06F3/014 ,  A61B5/0022 ,  A61B5/225 ,  A61B5/6806 ,  A61F2/583 ,  A61F5/0102 ,  A61F5/013 ,  A61H1/0288 ,  B25J13/025 ,  G06F3/016

Abstract: One aspect of the invention provides a wearable device including: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. Another aspect of the invention provides a wearable robotic device including a wearable device as described herein and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.

Abstract translation: 本发明的一个方面提供了一种可佩戴装置，其包括：至少一个适应和构造成放置在受试者的关节上的顺应性区域和耦合到顺应性区域的相对端的至少两个柔性但较不柔顺的区域。 本发明的另一方面提供了一种可佩戴的机器人装置，其包括如本文所述的可穿戴装置和至少一个致动器，其适于并构造成相对于彼此移动柔性但较不顺应的区域。

公开(公告)号：WO2008118867B1

公开(公告)日：2008-11-27

申请号：PCT/US2008058041

申请日：2008-03-24

Applicant: CLEARWIRE CORP ,  GELBMAN PETER P ,  WINTER MARK ADRIAN

Inventor： GELBMAN PETER P ,  WINTER MARK ADRIAN

IPC: H04L12/28 ,  H04W8/08 ,  H04W8/26 ,  H04W36/00 ,  H04W40/00 ,  H04W80/00 ,  H04W80/04 ,  H04W88/08

CPC classification number: H04W8/087 ,  H04L29/12028 ,  H04L61/103 ,  H04W8/26 ,  H04W40/00 ,  H04W80/04 ,  H04W88/08

Abstract: A network having an access service network ("ASN") configured to provide full mobility to mobile stations located within a service area. The ASN includes a Layer 2 or data link layer network that is larger, incorporates more nodes, or carries more data communications than Layer 2 networks incorporated in prior art ASNs. Data communications to and from the mobile stations are routed inside the ASN across the Layer 2 network which transports the data communication using a Layer 2 protocol. If the network includes another ASN located adjacent to the first ASN, the two ASNs may communicate directly with one another over a Layer 2 connection. If the network includes another ASN that is not adjacent to the first, Mobile Internet Protocol components may be included in the ASNs and configured to provide mobility between ASNs.

Abstract translation: 具有接入服务网络（“ASN”）的网络被配置为向位于服务区域内的移动站提供完全移动性。 ASN包括比现有技术的ASN中并入的第2层网络或数据链路层网络更多的网络，并入更多的节点，或者传输比第2层网络更多的数据通信。 到移动站和从移动站的数据通信在ASN内部跨越通过第2层协议传输数据通信的第2层网络。 如果网络包括位于与第一ASN相邻的另一个ASN，那么两个ASN可以通过二层连接直接相互通信。 如果网络包括不与第一ASN相邻的另一个ASN，则移动因特网协议组件可以被包括在ASN中并被配置为提供ASN之间的移动性。

公开(公告)号：WO1997010825A1

公开(公告)日：1997-03-27

申请号：PCT/US1996015135

申请日：1996-09-20

Applicant: ELI LILLY AND COMPANY ,  BELL, Michael, G. ,  CROWELL, Thomas, A. ,  DROSTE, Christine, A. ,  JESUDASON, Cynthia, D. ,  MATTHEWS, Donald, P. ,  MCDONALD, John, H., III ,  NEEL, David, A. ,  RITO, Christopher, J. ,  SHUKER, Anthony, J. ,  WINTER, Mark, A.

Inventor： ELI LILLY AND COMPANY

IPC: A61K31/44

CPC classification number: C07D209/08 ,  A61K31/404 ,  A61K31/4192 ,  C07D235/06 ,  C07D235/26 ,  C07D249/18 ,  C07D263/58 ,  C07D285/14 ,  C07D401/12 ,  C07D403/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

Abstract: The present invention is in the field of medicine, particularly in the treatment of Type II diabetes and obesity. More specifically, the present invention relates to selective beta 3 adrenergic receptor agonists useful in the treatment of Type II diabetes and obesity. The invention provides compounds and method of treating Type II diabetes, comprising administering to a mammal in need thereof compounds of Formulas (I) and (II).

Abstract translation: 本发明在医药领域，特别是治疗II型糖尿病和肥胖症。 更具体地，本发明涉及可用于治疗II型糖尿病和肥胖症的选择性β3肾上腺素能受体激动剂。 本发明提供了治疗II型糖尿病的化合物和方法，包括向有需要的哺乳动物施用式（I）和（II）的化合物。

公开(公告)号：WO2011094236A3

公开(公告)日：2011-08-04

申请号：PCT/US2011/022476

申请日：2011-01-25

Applicant: HERRINGTON, Rodney ,  DRESTY, John E. ,  WINTER, Mark K.

Inventor： HERRINGTON, Rodney ,  DRESTY, John E. ,  WINTER, Mark K.

IPC: B01D63/10 ,  B01D61/00

Abstract: Filtration systems (40) utilize a pre-treatment method to cause scale formation to occur on particles (94) in the fluid stream (96) rather than on the filter surface and may also destroy microorganisms in the fluid stream. More specifically, but not limited to, a filtration device can be a filtration membrane, such as spiral wound filtration membrane (60), that utilizes an open feed spacer (80), such for example an embossed or printed pattern on the membrane, to create a thin feed spacer channel which replaces a conventional feed spacer mesh material. System (40) further utilizes a treatment device (54) to enable a pulsed power, magnetic, electro-magnetic, electro-static, or hydrodynamic fluid treatment scheme to condition particles in the fluid stream (96) such that scale forming elements precipitate (94) on to the particles in the fluid stream rather than on the filtration surfaces.

Abstract translation: 过滤系统（40）利用预处理方法在流体流（96）中的颗粒（94）上而不是在过滤器表面上形成水垢，并且还可以破坏 流体流。 更具体地，但不限于，过滤装置可以是过滤膜，例如螺旋缠绕的过滤膜（60），其利用开放进料间隔件（80），例如膜上的压花或印刷图案， 创建一个取代传统进料间隔网材料的细料进料间隔物通道。 系统（40）进一步利用处理装置（54）来实现脉冲功率，磁性，电磁，静电或流体动力学流体处理方案以调节流体流（96）中的颗粒，使得水垢形成元素沉淀（ 94）到流体流中的颗粒上而不是在过滤表面上。

公开(公告)号：WO2008118867A1

公开(公告)日：2008-10-02

申请号：PCT/US2008/058041

申请日：2008-03-24

Applicant: CLEARWIRE CORPORATION ,  GELBMAN, Peter. P. ,  WINTER, Mark, Adrian

Inventor： GELBMAN, Peter. P. ,  WINTER, Mark, Adrian

IPC: H04Q7/38 ,  H04L12/28 ,  H04Q7/22

CPC classification number: H04W8/087 ,  H04L29/12028 ,  H04L61/103 ,  H04W8/26 ,  H04W40/00 ,  H04W80/04 ,  H04W88/08

Abstract: A network having an access service network ("ASN") configured to provide full mobility to mobile stations located within a service area. The ASN includes a Layer 2 or data link layer network that is larger, incorporates more nodes, or carries more data communications than Layer 2 networks incorporated in prior art ASNs. Data communications to and from the mobile stations are routed inside the ASN across the Layer 2 network which transports the data communication using a Layer 2 protocol. If the network includes another ASN located adjacent to the first ASN, the two ASNs may communicate directly with one another over a Layer 2 connection. If the network includes another ASN that is not adjacent to the first, Mobile Internet Protocol components may be included in the ASNs and configured to provide mobility between ASNs.

Abstract translation: 具有接入服务网络（“ASN”）的网络被配置为向位于服务区域内的移动台提供全部移动性。 ASN包括比现有技术ASN中包含的层2网络更大，结合更多节点或承载更多数据通信的层2或数据链路层网络。 与移动台之间的数据通信在ASN内通过使用第2层协议传输数据通信的第2层网络进行路由。 如果网络包括位于第一ASN附近的另一个ASN，则两个ASN可以通过层2连接彼此直接通信。 如果网络包含另一个与第一个不相邻的ASN，则移动互联网协议组件可以被包括在ASN中并被配置为在ASN之间提供移动性。

公开(公告)号：WO2008015458A2

公开(公告)日：2008-02-07

申请号：PCT/GB2007002967

申请日：2007-08-03

Applicant: ITI SCOTLAND LTD ,  TRIBE RAGLAN ,  MACLAUCHLAN KEN ,  FREEMAN PAUL ,  FREY COLIN ,  MCSPADDEN STEPHEN ,  WINTER MARK ,  WINNINGTON-INGRAM PETER

Inventor： TRIBE RAGLAN ,  MACLAUCHLAN KEN ,  FREEMAN PAUL ,  FREY COLIN ,  MCSPADDEN STEPHEN ,  WINTER MARK ,  WINNINGTON-INGRAM PETER

IPC: G06Q10/00

CPC classification number: G06Q10/10 ,  G06Q10/06375

Abstract: A method for authenticating a workflow that has one or more designated steps that require authentication of associated resources, the method comprising: using a reader instrument to read at least one security feature uniquely associated resources involved in the workflow; authenticating the security feature, thereby to authenticate its associated resource, and recording authentication information for each designated workflow step.

Abstract translation: 一种用于验证具有一个或多个指定步骤的工作流的方法，所述步骤需要对相关资源的认证，所述方法包括：使用读取器工具来读取所述工作流中涉及的唯一相关资源的至少一个安全特征; 认证安全特征，从而验证其相关资源，并为每个指定的工作流步骤记录认证信息。

公开(公告)号：WO1997017069A1

公开(公告)日：1997-05-15

申请号：PCT/US1996017533

申请日：1996-11-04

Applicant: ELI LILLY AND COMPANY ,  DANTZIG, Anne, H. ,  GRESE, Timothy, A. ,  NORMAN, Bryan, H. ,  PALKOWITZ, Alan, D. ,  SLUKA, James, P. ,  STARLING, James, J., II ,  WINTER, Mark, A.

Inventor： ELI LILLY AND COMPANY

IPC: A61K31/38

CPC classification number: C07D333/56 ,  A61K31/4535

Abstract: This invention provides a series of substituted benzo[b]thiophenes useful in reversing multidrug resistance in a resistant neoplasm. The present invention also provides methods for reversing the multidrug resistance in a resistant neoplasm by treating a mammal in need of said treatment with a substituted benzothiophene. This invention also provides methods for treating neoplasms in a mammal which comprises administering to a mammal in need of this treatment a substituted benzothiophene in combination with an oncolytic agent.

Abstract translation: 本发明提供一系列用于逆转耐药性肿瘤中多药耐药性的取代的苯并[b]噻吩。 本发明还提供了通过用取代的苯并噻吩处理需要所述治疗的哺乳动物来逆转耐药性肿瘤中的多药耐药性的方法。 本发明还提供了用于治疗哺乳动物肿瘤的方法，其包括向需要这种治疗的哺乳动物施用取代的苯并噻吩与溶瘤剂组合。

公开(公告)号：WO2011094236A2

公开(公告)日：2011-08-04

申请号：PCT/US2011022476

申请日：2011-01-25

Applicant: HERRINGTON RODNEY ,  DRESTY JOHN E ,  WINTER MARK K

Inventor： HERRINGTON RODNEY ,  DRESTY JOHN E ,  WINTER MARK K

IPC: B01D63/10 ,  B01D61/00

CPC classification number: B01D63/12 ,  B01D61/022 ,  B01D61/025 ,  B01D61/04 ,  B01D63/103 ,  B01D2311/04 ,  B01D2313/143 ,  B01D2317/022 ,  B01D2325/48 ,  C02F1/441 ,  C02F1/48 ,  C02F1/484 ,  C02F2303/22 ,  Y02A20/131 ,  B01D2311/2603 ,  B01D2311/2607

Abstract: Filtration systems (40) utilize a pre-treatment method to cause scale formation to occur on particles (94) in the fluid stream (96) rather than on the filter surface and may also destroy microorganisms in the fluid stream. More specifically, but not limited to, a filtration device can be a filtration membrane, such as spiral wound filtration membrane (60), that utilizes an open feed spacer (80), such for example an embossed or printed pattern on the membrane, to create a thin feed spacer channel which replaces a conventional feed spacer mesh material. System (40) further utilizes a treatment device (54) to enable a pulsed power, magnetic, electro-magnetic, electro-static, or hydrodynamic fluid treatment scheme to condition particles in the fluid stream (96) such that scale forming elements precipitate (94) on to the particles in the fluid stream rather than on the filtration surfaces.

Abstract translation: 过滤系统（40）利用预处理方法使流体流（96）中的颗粒（94）而不是在过滤器表面上发生结垢，并且也可能破坏流体流中的微生物。 更具体地但不限于，过滤装置可以是过滤膜，例如螺旋卷绕过滤膜（60），其利用打开的进料间隔物（80），例如膜上的压花或印刷图案， 创建一个替代常规进料间隔物网材料的细进料间隔物通道。 系统（40）还利用处理装置（54）来实现脉冲功率，磁性，电磁，静电或流体动力学流体处理方案来调节流体流（96）中的颗粒，使得结垢元件沉淀（ 94）到流体流中的颗粒而不是过滤表面上。

公开(公告)号：WO2009021049A2

公开(公告)日：2009-02-12

申请号：PCT/US2008072350

申请日：2008-08-06

Applicant: CLEARWIRE CORP ,  GELBMAN PETER P ,  SEWELL JEFFREY ,  WINTER MARK ADRIAN

Inventor： GELBMAN PETER P ,  SEWELL JEFFREY ,  WINTER MARK ADRIAN

IPC: H04L12/24 ,  H04L12/56

CPC classification number: H04L12/14 ,  H04L12/1403 ,  H04L12/1425 ,  H04L12/1428 ,  H04L41/5003 ,  H04L47/2491

Abstract: A subscriber management system for a communication system having a radio access network coupled to by a gateway node to a packet switched network. The system consolidates three prior art subscriber management system components, a DPI device, a QoS Policy Manager 40, and an Application Manager 28, into a DPI platform. The system also relocates functions to the DPI platform that were previously provided by the gateway node in prior art networks. Specifically, an Accounting Client 34, a Hotlining function 36, and a QoS SFA function 44 are located to the DPI platform. By consolidating network components and relocating functions to the DPI platform, the number of control interfaces in the network can be reduced. Further, network components produced by different vendors may be integrated more easily. A method of implementing hotlining in the system is also provided.

Abstract translation: 一种用于具有通过网关节点耦合到分组交换网络的无线电接入网络的通信系统的订户管理系统。 该系统将三个现有技术订户管理系统组件，DPI设备，QoS策略管理器40和应用管理器28合并到DPI平台中。 该系统还将功能重新定位到先前在现有技术网络中由网关节点提供的DPI平台。 具体而言，计费客户端34，热线功能36以及QoS SFA功能44位于DPI平台。 通过整合网络组件和将功能重新定位到DPI平台，可以减少网络中控制接口的数量。 此外，不同供应商生产的网络组件可能更容易集成。 还提供了一种在系统中实现热线的方法。

公开(公告)号：WO2015134336A3

公开(公告)日：2015-12-17

申请号：PCT/US2015018192

申请日：2015-02-27

Applicant: UNIV DREXEL ,  COHEN ANDREW ,  DION GENEVIEVE ,  WINTER MARK ,  WAIT ERIC ,  KOERNER MICHAEL

Inventor： COHEN ANDREW ,  DION GENEVIEVE ,  WINTER MARK ,  WAIT ERIC ,  KOERNER MICHAEL

IPC: A61H1/02

CPC classification number: G06F3/014 ,  A61B5/0022 ,  A61B5/225 ,  A61B5/6806 ,  A61F2/583 ,  A61F5/0102 ,  A61F5/013 ,  A61H1/0288 ,  B25J13/025 ,  G06F3/016

Abstract: One aspect of the invention provides a wearable device including: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. Another aspect of the invention provides a wearable robotic device including a wearable device as described herein and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.

Abstract translation: 本发明的一个方面提供了一种可穿戴设备，包括：至少一个柔性区域，其被适配和构造成放置在对象的关节上方;以及至少两个柔性但柔顺性较低的区域，其被耦合到柔性区域的相对端部。 本发明的另一方面提供了一种可穿戴式机器人设备，其包括如本文所述的可穿戴设备以及至少一个致动器，所述至少一个致动器适于并构造成使柔性但柔顺性较小的区域相对于彼此移动。