公开(公告)号：WO2013006762A3

公开(公告)日：2013-03-14

申请号：PCT/US2012045690

申请日：2012-07-06

申请人： UNIV CALIFORNIA ,  LU YUNFENG ,  YAN MING ,  LIU YANG

发明人： LU YUNFENG ,  YAN MING ,  LIU YANG

IPC分类号： C12N11/00 ,  A61K38/00 ,  C12N9/00

CPC分类号： A61K38/443 ,  A61K38/44 ,  A61K47/549 ,  B82Y5/00 ,  C12N11/18

摘要： Provided are nanocomplexes having at least two different enzymes and a polymeric network anchored to at least one of the enzymes. In some embodiments, the activities of the enzymes catalyze a cascade reaction.

摘要翻译： 提供具有至少两种不同的酶和锚定于至少一种酶的聚合物网络的纳米复合物。 在一些实施方案中，酶的活性催化级联反应。

公开(公告)号：WO2010052609A2

公开(公告)日：2010-05-14

申请号：PCT/IB2009/054766

申请日：2009-10-28

申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  CHEN, Dayu ,  YAN, Ming ,  JIN, Hua

发明人： CHEN, Dayu ,  YAN, Ming ,  JIN, Hua

IPC分类号： G01V3/10

CPC分类号： G01V3/104

摘要： The invention relates to a coil arrangement comprising at least one transmitting coil for generating a primary magnetic field; and a plurality of measurement coils; wherein the at least one transmitting coil (408, 409) and the plurality of measurement coils (410, 411) are arranged in such a way that the flux curve of the primary magnetic field generated by a transmitting coil (409) among said at least one transmitting coil (408, 409) passes into and out of a first measurement coil (410) among said plurality of measurement coils (410, 411), the first measurement coil being the coil closest to the transmitting coil. By enabling the flux of the primary magnetic field to pass into and out of a first measurement coil, the signal induced on the first measurement coil by the positive and negative flux can be compensated, resulting in a reduction of the signal strength of the induced signal on the measurement coil and the signal dynamic range.

摘要翻译： 本发明涉及一种线圈装置，其包括至少一个用于产生初级磁场的传输线圈; 和多个测量线圈; 其中所述至少一个发射线圈（408,409）和所述多个测量线圈（410,411）以这样的方式布置，使得由所述至少一个发射线圈（409）产生的所述初级磁场的磁通曲线 一个发射线圈（408,409）在所述多个测量线圈（410,411）之间进入和离开第一测量线圈（410），第一测量线圈是最靠近发射线圈的线圈。 通过使一次磁场的磁通量能够通过和流出第一测量线圈，可以补偿在第一测量线圈上由正和负磁通感应的信号，导致感应信号的信号强度的降低 在测量线圈和信号动态范围内。

公开(公告)号：WO2008082788A1

公开(公告)日：2008-07-10

申请号：PCT/US2007/083777

申请日：2007-11-06

申请人： MOTOROLA, INC. ,  CHENG, Yan Ming

发明人： CHENG, Yan Ming

IPC分类号： G10L15/00

CPC分类号： G10L15/148

摘要： One provides (101) a plurality of frames of sampled audio content and then processes (102) that plurality of frames using a speech recognition search process that comprises, at least in part, searching for at least two of state boundaries, subword boundaries, and word boundaries using different search resolutions.

摘要翻译： 一个提供（101）多个采样音频内容的帧，然后使用语音识别搜索处理（102）处理（102）多个帧，该处理至少部分地包括搜索状态边界，子词边界和 字边界使用不同的搜索分辨率。

公开(公告)号：WO2007075175A1

公开(公告)日：2007-07-05

申请号：PCT/US2005/047513

申请日：2005-12-29

申请人： NEOPHOTONICS CORPORATION ,  YAN, Ming ,  TICKNOR, Anthony, J. ,  HO, Calvin ,  XU, Hao ,  WEAVER, Jason ,  TARTER, Thomas, S. ,  LAM, Jane

发明人： YAN, Ming ,  TICKNOR, Anthony, J. ,  HO, Calvin ,  XU, Hao ,  WEAVER, Jason ,  TARTER, Thomas, S. ,  LAM, Jane

IPC分类号： G02B6/12 ,  G02B6/26 ,  G02B6/28 ,  G02B6/34 ,  G02B6/42

CPC分类号： G02B6/12026 ,  G02B6/12011 ,  G02B2006/12135

摘要： A linearized thermal and optical model of an optical integrated circuit can be used to temperature-stabilize one or more optical elements of the circuit (455) using active temperature regulation. To stabilize a single optical element, such as an arrayed waveguide grating (AWG), a temperature sensor (425) and a heater (427) can be provided proximate to the grating. Thermal and optical coefficients can be then used to select an appropriate temperature set-point for the temperature controller (400) that receives readings from the sensor and determines the power dissipated in the heater. Multiple AWG's can be stabilized individually, lumping cross- heating factors together with other environmental factors.

摘要翻译： 可以使用光学集成电路的线性化热和光学模型来使用主动温度调节来温度稳定电路（455）的一个或多个光学元件。 为了稳定诸如阵列波导光栅（AWG）的单个光学元件，可以在光栅附近提供温度传感器（425）和加热器（427）。 然后可以使用热和光系数来为接收来自传感器的读数的温度控制器（400）选择适当的温度设定点，并确定加热器中消耗的功率。 多个AWG可以单独稳定，将交叉加热因素与其他环境因素结合。

公开(公告)号：WO2002085404A1

公开(公告)日：2002-10-31

申请号：PCT/US2002/010391

申请日：2002-04-01

申请人： NATIONAL YAN-MING UNIVERSITY ,  ADLMMUNE CORPORATION ,  SU, Jin-Yuan ,  CHOU, Chen-Kung ,  LIU, Wei-Kuang ,  TSOU, Ann-Ping

发明人： SU, Jin-Yuan ,  CHOU, Chen-Kung ,  LIU, Wei-Kuang ,  TSOU, Ann-Ping

IPC分类号： A61K38/16

CPC分类号： G01N33/573 ,  A61K38/00 ,  C07K14/4702 ,  G01N2333/4704 ,  G01N2333/9121

摘要： The invention relates to a new protein that binds to LKB1, a protein associated with Peutz-Jeghers Syndrome, and suppresses NFκB's transcriptional activity.

摘要翻译： 本发明涉及结合LKB1的蛋白质，该蛋白质是与Peutz-Jeghers综合征相关的蛋白质，并抑制NFκB的转录活性。

公开(公告)号：WO2012117337A1

公开(公告)日：2012-09-07

申请号：PCT/IB2012/050897

申请日：2012-02-27

申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. ,  YAN, Ming ,  CHEN, Yinan

发明人： YAN, Ming ,  CHEN, Yinan

IPC分类号： A61B5/022 ,  A61B8/06 ,  A61B8/08

CPC分类号： A61B8/06 ,  A61B5/022 ,  A61B8/08 ,  A61B8/0891 ,  A61B8/42 ,  A61B8/488

摘要： The method of positioning a Doppler ultrasound transducer for performing blood flow measurement according to the invention comprises the steps of: detecting a pressure oscillation signal from an inflated cuff placed on patient's artery; detecting an ultrasound pulse signal from the Doppler ultrasound transducer placed along the artery; deriving a first signal from the pressure oscillation signal and the ultrasound pulse signal, the first signal indicating the degree of synchronization between the pressure oscillation signal and the ultrasound pulse signal; and outputting an indication signal to indicate the Doppler ultrasound transducer is in a desired position when the first signal satisfies a predefined condition. Since the synchronization property of the cuff pressure oscillation signal and the ultrasound signal caused by the blood flow is utilized to determine whether the transducer is well positioned or not, ultrasound signal, which is a pulse signal but not reflecting the blood flow of the artery, could be determined as not in synchronization with the oscillation signal and therefore the accuracy of the positioning could be improved.

摘要翻译： 根据本发明的定位用于执行血流测量的多普勒超声换能器的方法包括以下步骤：从放置在患者动脉上的充气袖带检测压力振荡信号; 检测来自沿着动脉放置的多普勒超声换能器的超声脉冲信号; 从所述压力振荡信号和所述超声脉冲信号中导出第一信号，所述第一信号指示所述压力振荡信号与所述超声脉冲信号之间的同步度; 并且当所述第一信号满足预定条件时，输出指示多普勒超声换能器的指示信号处于期望位置。 由于袖带压力振荡信号与由血流引起的超声波信号的同步性被利用来确定换能器是否良好定位，作为脉冲信号而不反映动脉血流的超声波信号， 可以确定为不与振荡信号同步，因此可以提高定位的精度。

公开(公告)号：WO2012009262A3

公开(公告)日：2012-01-19

申请号：PCT/US2011/043528

申请日：2011-07-11

申请人： YUNG SHIN PHARM. IND. CO., LTD. ,  CARLSBAD TECHNOLOGY, INC. ,  CHEN, Chia-Hui ,  HUANG, Yu-Liang ,  KUNG, Liang-Rern ,  YAN, Ming-Chung

发明人： CHEN, Chia-Hui ,  HUANG, Yu-Liang ,  KUNG, Liang-Rern ,  YAN, Ming-Chung

IPC分类号： A61K31/195 ,  A61K31/185 ,  A61K31/135 ,  A61P35/00 ,  A61P19/10

摘要： The present invention relates to a compound of diclofenac-tramadol salt in 1:1 ratio and a pharmaceutical formulation comprising such compound. The present invention also relates to a method for treating a patient with moderate to moderately severe pain. The method comprises: identifying a patient suffering from moderate to moderately severe pain with pain intensity scale of 5-9, and administering to said patient the diclofenac-tramadol salt, in an effective amount. The method is particularly useful in treating postoperative pain after Cesarean, postoperative pain after non-Cesarean surgeries, cancer pain, osteoarthritis pain, or rheumatoid arthritis pain.

公开(公告)号：WO2011163404A1

公开(公告)日：2011-12-29

申请号：PCT/US2011/041507

申请日：2011-06-22

申请人： QUALCOMM INCORPORATED ,  CANPOLAT, Bahadir ,  YAN, Ming ,  ABRISHAMKAR, Farrokh ,  SIKRI, Divaydeep

发明人： CANPOLAT, Bahadir ,  YAN, Ming ,  ABRISHAMKAR, Farrokh ,  SIKRI, Divaydeep

IPC分类号： H04L25/03

CPC分类号： H04L25/0328 ,  H04L25/0242 ,  H04L25/03292 ,  H04L2025/03726

摘要： A signal reception method includes receiving a signal over a channel, producing a first equalized signal, a first interference suppression filter and a first estimate of the channel using a portion of a the received signal, dividing the received signal into a plurality of signal blocks, and for each one of the plurality of signal blocks, producing a second equalized signal using a portion of the first equalized signal by selecting from one of a linear estimator or a non-linear estimator and estimating symbols received in the one of the plurality of signal blocks based on the second equalized signal.

摘要翻译： 信号接收方法包括通过信道接收信号，使用接收信号的一部分产生第一均衡信号，第一干扰抑制滤波器和信道的第一估计，将接收信号分成多个信号块， 并且对于所述多个信号块中的每一个，使用所述第一均衡信号的一部分，通过从线性估计器或非线性估计器之一中选择并估计在所述多个信号中的一个信号中接收的符号来产生第二均衡信号 基于第二均衡信号的块。

公开(公告)号：WO2010029465A3

公开(公告)日：2011-05-12

申请号：PCT/IB2009053817

申请日：2009-09-02

申请人： KONINKL PHILIPS ELECTRONICS NV ,  YAN MING ,  CHEN DAYU ,  JIN HUA

发明人： YAN MING ,  CHEN DAYU ,  JIN HUA

IPC分类号： G01V3/10

CPC分类号： G01V3/104 ,  A61B5/0522 ,  A61B5/0536

摘要： The invention relates to a method and a system for magnetic induction tomography, the system comprising: at least one transmitting coil (312, 314) for generating a primary magnetic field to be applied to the object of interest (301); and at least one measurement coil arrangement (315, 317) for measuring electric signals induced by a secondary magnetic field which is generated by the object of interest in response to the primary magnetic field, wherein the at least one measurement coil arrangement comprises a plurality of measurement coils which are positioned in substantially the same plane. By using a plurality of independent measurement coils positioned in a plane so as to replace a conventional single measurement coil, the measurement coil across which the measured difference voltage is most sensitive to a change of the secondary magnetic field can be selected for calculating the change of conductivity distribution, resulting in an improved sensitivity of a MIT system.

摘要翻译： 本发明涉及一种用于磁感应断层摄影的方法和系统，该系统包括：用于产生要施加到感兴趣对象（301）的主磁场的至少一个发射线圈（312,314）; 以及用于测量由所述感兴趣对象响应于所述主磁场产生的次级磁场感应的电信号的至少一个测量线圈装置（315,317），其中所述至少一个测量线圈装置包括多个 测量线圈位于基本相同的平面中。 通过使用位于平面中的多个独立的测量线圈来代替常规的单个测量线圈，可以选择测量的差分电压对次级磁场的变化最敏感的测量线圈，以计算 电导率分布，导致MIT系统的灵敏度提高。

公开(公告)号：WO2010052609A3

公开(公告)日：2011-04-21

申请号：PCT/IB2009054766

申请日：2009-10-28

申请人： KONINKL PHILIPS ELECTRONICS NV ,  CHEN DAYU ,  YAN MING ,  JIN HUA

发明人： CHEN DAYU ,  YAN MING ,  JIN HUA

IPC分类号： G01V3/10

CPC分类号： G01V3/104

摘要： The invention relates to a coil arrangement comprising at least one transmitting coil for generating a primary magnetic field; and a plurality of measurement coils; wherein the at least one transmitting coil (408, 409) and the plurality of measurement coils (410, 411) are arranged in such a way that the flux curve of the primary magnetic field generated by a transmitting coil (409) among said at least one transmitting coil (408, 409) passes into and out of a first measurement coil (410) among said plurality of measurement coils (410, 411), the first measurement coil being the coil closest to the transmitting coil. By enabling the flux of the primary magnetic field to pass into and out of a first measurement coil, the signal induced on the first measurement coil by the positive and negative flux can be compensated, resulting in a reduction of the signal strength of the induced signal on the measurement coil and the signal dynamic range.

摘要翻译： 本发明涉及一种线圈装置，其包括至少一个用于产生初级磁场的传输线圈; 和多个测量线圈; 其中所述至少一个发射线圈（408,409）和所述多个测量线圈（410,411）以这样的方式布置，使得由所述至少一个发射线圈（409）产生的所述初级磁场的磁通曲线 一个发射线圈（408,409）在所述多个测量线圈（410,411）之间进入和离开第一测量线圈（410），第一测量线圈是最靠近发射线圈的线圈。 通过使一次磁场的磁通量能够通过和流出第一测量线圈，可以补偿在第一测量线圈上由正和负磁通感应的信号，导致感应信号的信号强度的降低 在测量线圈和信号动态范围内。