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    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR
    1.
    发明申请
    DUAL-PHASE CEMENT PRECURSOR SYSTEMS FOR BONE REPAIR 审中-公开
    用于骨修复的双相水泥前体系统

    公开(公告)号：WO2007047921A3

    公开(公告)日：2007-05-24

    申请号：PCT/US2006041034

    申请日：2006-10-19

    Applicant: ADA FOUNDATION ,  CHOW LAURENCE C ,  TAKAGI SHOZO

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61K33/42 ,  A61K31/19

    CPC classification number: A61K33/42 ,  A61K45/06 ,  A61L24/02 ,  A61L27/12 ,  A61L27/46 ,  A61L27/50 ,  A61L27/58 ,  A61K2300/00 ,  C08L89/00

    Abstract: Disclosed are dual-phase cement precursor systems and related methods and kits. The cement precursor systems are composed of a first and second discrete phases, at least one of which is aqueous. When combined, the cement precursor phases form a cement that is suitable as a bone graft material for bone repair procedures. In preferred embodiments, the materials are highly biocompatible, osteoinductive, and bioresorbable. A number of different but not mutually exclusive cement chemistries may be employed in the cement precursor systems. For instance, hydrogel-forming polymer cements, carboxyl/calcium cements, or calcium phosphate cements may be employed.

    Abstract translation: 公开了双相水泥前体体系及相关方法和试剂盒。 水泥前体体系由第一和第二离散相组成，其中至少一个是水性的。 当组合时，水泥前体相形成适合作为骨修复程序的骨移植材料的水泥。 在优选的实施方案中，所述材料是高生物相容性的，骨诱导性的和生物可再吸收的。 在水泥前体体系中可以使用许多不同但不相互排斥的水泥化学物质。 例如，可以使用水凝胶形成聚合物水泥，羧基/钙水泥或磷酸钙水泥。

    DENTAL AND ENDODONTIC FILLING MATERIALS AND METHODS
    2.
    发明申请
    DENTAL AND ENDODONTIC FILLING MATERIALS AND METHODS 审中-公开
    牙科和内膜灌注材料与方法

    公开(公告)号：WO2007047994A3

    公开(公告)日：2007-10-11

    申请号：PCT/US2006041164

    申请日：2006-10-19

    Applicant: ADA FOUNDATION ,  CHOW LAURENCE C ,  TAKAGI SHOZO

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61K9/70

    CPC classification number: A61C5/50 ,  A61K6/0038 ,  A61K6/0067 ,  A61K6/0606 ,  A61K6/0612 ,  A61K6/0625 ,  A61K6/0643 ,  A61K6/097 ,  C08L31/04 ,  C08L1/284 ,  C08L5/04 ,  C08L29/04 ,  C08L33/08 ,  C08L5/08 ,  C08L5/06

    Abstract: Disclosed are endodontic filling materials and methods. A method for filling a dental root canal may include providing a hydrosetting filling material and inserting the hydrosetting filling material into the dental root canal, the material setting in the root canal to form a biocompatible filling. The hydrosetting filling material comprises a hydrogel former and a filler. The hydrogel former is at least one of a reactive organic hydrogel formers, an inorganic hydrogel formers, and a non-reactive organic hydrogel formers, and the filler is at least one of a self-hardening and a non-hardening filler. Plural filling material precursor compositions that collectively contain hydrogel formers and fillers may be provided.

    Abstract translation: 公示的是根管填充材料和方法。 用于填充牙根管的方法可以包括提供水合物填充材料并将水合物填充材料插入牙根管，根管中设置的材料以形成生物相容的填充物。 水凝胶填充材料包括水凝胶形成剂和填料。 水凝胶形成剂是反应性有机水凝胶形成剂，无机水凝胶形成剂和非反应性有机水凝胶形成剂中的至少一种，填料是自硬化和非硬化填料中的至少一种。 可以提供集体含有水凝胶形成剂和填料的多种填充材料前体组合物。

    FLUORIDE-CALCIUM COMPOSITIONS, DENTAL PRODUCTS, AND METHODS FOR PROVIDING DENTAL FLUORIDE
    3.
    发明申请
    FLUORIDE-CALCIUM COMPOSITIONS, DENTAL PRODUCTS, AND METHODS FOR PROVIDING DENTAL FLUORIDE 审中-公开
    氟化钙组合物，牙科产品和用于提供牙科氟化物的方法

    公开(公告)号：WO2007050684A3

    公开(公告)日：2009-04-30

    申请号：PCT/US2006041631

    申请日：2006-10-25

    Applicant: ADA FOUNDATION ,  CHOW LAURENCE C ,  TAKAGI SHOZO

    Inventor： CHOW LAURENCE C ,  TAKAGI SHOZO

    IPC: A61K8/21 ,  A61K8/00

    CPC classification number: A61Q11/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24

    Abstract: Disclosed are dental compositions and methods. In accordance with one embodiment, a dental composition includes calcium, fluorine, which is generally present in the form of fluoride, and phosphate or another stabilizing anion. The composition is stable as against precipitation of calcium fluoride during transport and storage, but is unstable against the precipitation of calcium fluoride in the oral cavity of a human. In many embodiments, the amount of fluoride may be less than the amount of fluoride used in a comparable composition intended for a similar purpose. A dental method comprises applying the composition to the oral cavity of a patient, whereupon calcium fluoride precipitates from the composition.

    Abstract translation: 公开了牙科用组合物和方法。 根据一个实施方案，牙科用组合物包括通常以氟化物形式存在的钙，氟，磷酸盐或其它稳定阴离子。 该组合物在运输和储存期间对于氟化钙的沉淀是稳定的，但是对于人体口腔中氟化钙的沉淀是不稳定的。 在许多实施方案中，氟化物的量可以小于用于类似目的的类似组合物中使用的氟化物的量。 牙科方法包括将组合物施用于患者的口腔，于是氟化钙从组合物中沉淀出来。

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