公开(公告)号：WO2015092575A1

公开(公告)日：2015-06-25

申请号：PCT/IB2014/066284

申请日：2014-11-24

Applicant: BASF SE ,  BASF (CHINA) COMPANY LIMITED

Inventor： PETZKE, Lutz ,  HEROLD, Andrea ,  FLECK, Christian ,  TREIER-MARXEN, Katrin ,  ÖDMAN, Peter ,  DICKHAUT, Joachim ,  WEINGARTEN, Melanie ,  LUZHETSKY, Andriy ,  REBETS, Yuriy ,  BRÖTZ, Elke ,  MANDERSCHEID, Niko ,  MYRONOVSKYI, Maksym

IPC: C12N1/21 ,  C12N15/10 ,  C12N15/31 ,  C12N15/76 ,  C12P1/06 ,  C12Q1/04 ,  C12R1/47

CPC classification number: C12N15/52 ,  C07K14/36 ,  C12P17/181

Abstract: Provided are polynucleotides and polypeptides involved in the biosynthesis of pamamycin and pamamycin precursors as well as vectors and recombinant microorganisms comprising the polynucleotides and polypeptides. Also provided are methods for the production of pamamycins, in particular pamamycin 607 and pamamycin 621, and their precursors.

Abstract translation: 提供参与帕米霉素和帕米霉素前体的生物合成以及包含多核苷酸和多肽的载体和重组微生物的多核苷酸和多肽。 还提供了生产帕拉霉素，特别是帕米霉素607和帕米霉素621及其前体的方法。

公开(公告)号：WO2018224939A1

公开(公告)日：2018-12-13

申请号：PCT/IB2018/053970

申请日：2018-06-04

Applicant: BASF SE ,  BASF (CHINA) COMPANY LIMITED

Inventor： PETZKE, Lutz ,  HEROLD, Andrea ,  LUZHETSKYY, Andriy ,  MYRONOVSKYI, Maksym ,  ROSENKRAENZER, Birgit ,  TOKOVENKO, Bogdan

IPC: C12N15/09 ,  C12N15/75 ,  C12P21/02

Abstract: The invention pertains to the field of production of albucidin. It provides polynucleotides and polypeptides involved in the biosynthesis of albucidin as well as recombinant microorganisms comprising such polynucleotides and polypeptides. Also provided are methods for the production of albucidin.