Abstract:
A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises a metallic piercing member (7) with two piercing elements (25) extending parallel to each other and inclined to a lid (27) of a blister pocket to be punctured.
Abstract:
An inhaler is proposed for delivering a preferably powdered formulation from a blister strip having a plurality of blister pockets. Each blister pockets is pierced such that an inlet opening and an outlet opening is formed in a lid of the respective blister pocket. A sealing is provided between the two openings and/or only around the outlet opening in order to avoid a bypass gas/air stream. Alternatively, a blister strip is proposed which comprises sealings on lids of its blister pockets.
Abstract:
The invention relates to an inhaler for the inhalation of powdery medicaments in a capsule form. Said capsules are inserted, prior to use, into a capsule holder (3) arranged inside the inhaler (3). After the capsule is inserted into the capsule holder, the patient can press the actuating element (8) which can be displaced from a resting position and which co-operates with at least one needle (9) pushed into the capsule holder. The aim of the invention is to further improve said type of inhalers with respect to operational comfort. Said aim is achieved by providing an embodiment of an inhaler wherein the actuating element is embodied as a multifunctional actuating element (8a), thereby enabling the cover (5) of the lower part (1) to pivot when the closing element (6) is inserted into a first functional position, and enabling the mouth piece (4), which is secured to the plate (2), to be removed from the plate in a second functional position in such a manner that the mouth piece can be pivoted away from the lower part.
Abstract:
The invention relates to a nozzle system for a liquid discharge device, comprising a nozzle and a device which fixes the nozzle in the discharge device. The device comprises a liquid reservoir which pressurises the liquid through a nozzle in order to discharge liquid. The nozzle is fixed to the discharge device by a holding device. Said holding device can be automatically maintained by a second holding device, e.g. in the form of a coupling nut, or the coupling nut is the holding device. According to the invention, at least one part of the outer surface of the holding device is micro or nanostructured.
Abstract:
The invention relates to a method that, for the first time, is provided for applications within the pharmaceutical industry, during which the particle size of atomized aerosols is measured simultaneously or in succession by using the laser diffraction method and the cascade impactor method recognized in the profession. This enables the reliability of the results of the inventive laser diffraction method to be aligned with those of the cascade impactor and thus to create a method which combines the advantages of the rapid laser diffraction method with the precision of the otherwise time-intensive cascade impactor method. The invention also relates to devices for carrying out the method.
Abstract:
The invention relates to an adapter (23), and inhalation device (32), and an atomizer (1) having such an adapter or such an inhalation device. At least one connector (24) for connecting to an atomizer and one patient-side connection (27) is provided on the adapter, preferably fluidically connected to each other in an unbranched manner. The inhalation device comprises a chamber (38) for intermediately storing an aerosol. A connection (33) for the atomizer, a patient-side connection (34), and a third connection (35) for breathable air can be provided on the inhalation device. The chamber is connected to the atomizer without any valves on the inlet side and is connected to the connection for breathable air on the inlet side by means of a valve (40), so that breathable air can flow from the breathable air connection into the chamber. The adapter can be connected to the inhalation device.
Abstract:
A dispensing device, a storage device and a method are proposed for dispensing a formulation as a spray. The formulation is dispensed by means of a gas stream. To improve the dispensing effect, pressure pulses are generated in the gas stream and/or the direction of gas flow alternates. The formulation is dispensed through a duct. The duct is connected to a storage chamber containing the formulation via a sharp edge or transition portion.
Abstract:
An inhaler (1) is proposed for the propellant-free nebulisation of a medicament preparation. The inhaler produces an aerosol at low speed. The inhaler is combined with an add-on device (23) for intermediate storage of the aerosol produced, so as to allow easier inhalation, particularly for children.
Abstract:
A passive inhaler (1) for delivery of a powder-form inhalation formulation from a blister strip (2) with a plurality of blister pockets (3) is proposed. The inhaler comprises an impaction element (31) onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device (35) for better de- agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.