公开(公告)号：WO2010043522A1

公开(公告)日：2010-04-22

申请号：PCT/EP2009/063024

申请日：2009-10-07

Applicant: DSM IP Assets B.V. ,  BONRATH, Werner ,  LETINOIS, Ulla ,  SCHÜTZ, Jan

Inventor： BONRATH, Werner ,  LETINOIS, Ulla ,  SCHÜTZ, Jan

IPC: C07C45/61 ,  C07C29/42 ,  C07C403/16 ,  C11B9/00 ,  A23L1/22

CPC classification number: C07C45/512 ,  A23L27/88 ,  C07C29/42 ,  C07C45/61 ,  C07C403/16 ,  C07C2601/14 ,  C11B9/0034 ,  C07C35/17 ,  C07C49/543 ,  C07C49/403

Abstract: A process for the preparation of 1-ethynyl-3,3-dimethylcyclohexan-1-ol from dimedone by a reaction sequence of reduction and ethynylation and its further transformation into green ketone.

Abstract translation: 通过还原和乙炔化的反应顺序从二酮制备1-乙炔基-3,3-二甲基环己烷-1-醇并进一步转化成绿酮的方法。

公开(公告)号：WO2019012000A1

公开(公告)日：2019-01-17

申请号：PCT/EP2018/068821

申请日：2018-07-11

Applicant: DSM IP ASSETS B.V.

Inventor： LETINOIS, Ulla ,  NETSCHER, Thomas

IPC: C07D311/72

Abstract: The present invention relates to a novel synthetic pathway for alpha- tocopherol. The invention discloses different reactions yielding some new intermediates in a very high yield and stereoselectivity.

公开(公告)号：WO2015110654A1

公开(公告)日：2015-07-30

申请号：PCT/EP2015/051599

申请日：2015-01-27

Applicant: DSM IP ASSETS B.V.

Inventor： BONRATH, Werner ,  LETINOIS, Ulla ,  NETSCHER, Thomas

IPC: C07C37/14

CPC classification number: C07C37/14 ,  B01J31/2273 ,  B01J31/2404 ,  B01J31/2409 ,  B01J2231/324 ,  B01J2531/18 ,  C07C39/07

Abstract: The present invention relates to a new method to produce 2,3,6-trimethylphenol (2,3,6-TMP).

Abstract translation: 本发明涉及一种生产2,3,6-三甲基苯酚（2,3,6-TMP）的新方法。

公开(公告)号：WO2009144136A1

公开(公告)日：2009-12-03

申请号：PCT/EP2009/055718

申请日：2009-05-12

Applicant: DSM IP ASSETS B.V. ,  BONRATH, Werner ,  LETINOIS, Ulla

Inventor： BONRATH, Werner ,  LETINOIS, Ulla

IPC: C07B35/02 ,  C07C45/61 ,  C07C49/403

CPC classification number: C07C45/65 ,  C07B35/02 ,  Y02P20/582 ,  C07C49/403

Abstract: The present invention is directed to a process for the manufacture of a mono-ketone comprising the step of hydrogenating a 1,3-diketone with hydrogen in the presence of a bifunctional catalyst having an acid functionality and a hydrogenation functionality.

Abstract translation: 本发明涉及一种制备单酮的方法，包括在具有酸官能度和氢化官能度的双官能催化剂存在下，用氢氢化1,3-二酮的步骤。

公开(公告)号：WO2015144832A1

公开(公告)日：2015-10-01

申请号：PCT/EP2015/056595

申请日：2015-03-26

Applicant: DSM IP ASSETS B.V.

Inventor： BONRATH, Werner ,  BEUMER, Raphael ,  LETINOIS, Ulla

IPC: C07C45/51 ,  C07C49/543

CPC classification number: C07C45/512 ,  B01J31/2404 ,  B01J2531/18 ,  C07C49/543

Abstract: The present invention relates to an improved method for producing of 1-(5,5- dimethylcyclohex-1-en-1-yl)ethanone and 1-(5,5-dimethylcyclohex-6-en-1- yl)ethanone.

Abstract translation: 本发明涉及1-（5,5-二甲基环己-1-烯-1-基）乙酮和1-（5,5-二甲基环己-6-烯-1-基）乙酮的改进方法。

公开(公告)号：WO2015028463A1

公开(公告)日：2015-03-05

申请号：PCT/EP2014/068080

申请日：2014-08-26

Applicant: DSM IP ASSETS B.V.

Inventor： LETINOIS, Ulla ,  NETSCHER, Thomas ,  STEMMLER, René Tobias

IPC: C07D311/70 ,  C07D311/72

CPC classification number: C07D311/70 ,  C07D311/72

Abstract: The present invention relates to the method of preparing chiral chromanes and chromenes in high yields by intramolecular hydroarylation of chiral aryl alkynes catalysed by either a silver(I) or gold(I) salt or complex in combination of a specific acid or by a silver(I) or gold(I) metal salt or complex having specific anion. By the hydroarylation a chromene is formed which has a chiral centre in the 2 position. The corresponding chromane is obtained by hydrogenation of the chromenes.

Abstract translation: 本发明涉及通过分子内加氢芳基化手性色烷和色烯的方法，所述手性芳基炔由银（I）或金（I）盐或络合物通过特定酸或银组合催化的手性芳基炔烃 I）或具有特定阴离子的金（I）金属盐或络合物。 通过加氢芳基化，形成了在2位具有手性中心的色烯。 通过色烯的氢化获得相应的苯并二氢吡喃。

公开(公告)号：WO2015001030A1

公开(公告)日：2015-01-08

申请号：PCT/EP2014/064208

申请日：2014-07-03

Applicant: DSM IP ASSETS B.V.

Inventor： LETINOIS, Ulla ,  NETSCHER, Thomas ,  ACKERMANN, Stephan

IPC: C07D311/22

CPC classification number: C07D311/22

Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one urea or thiourea.

Abstract translation: 本发明涉及在苯并二氢吡喃酮或苯并二氢吡喃环中2-位的立体特异性物质中的色满酮或色烷的合成。 已经发现，在具有特定类型的式的手性化合物和至少一种脲或硫脲的存在下，这种合成是特别有可能的。

公开(公告)号：WO2019206892A1

公开(公告)日：2019-10-31

申请号：PCT/EP2019/060344

申请日：2019-04-23

Applicant: DSM IP ASSETS B.V.

Inventor： LAEUGER, Stefan Karl ,  LETINOIS, Ulla ,  RIEBEL, Peter

IPC: C07C203/04 ,  A23K20/174 ,  A23K20/105 ,  A23K50/10 ,  C11C3/04 ,  A23K20/158

Abstract: The present invention relates to novel dicarboxylic diesters as well as the use thereof as for inhibiting the methane production in ruminants.

公开(公告)号：WO2017108339A1

公开(公告)日：2017-06-29

申请号：PCT/EP2016/079016

申请日：2016-11-28

Applicant: DSM IP ASSETS B.V.

Inventor： ACKERMANN, Stephan ,  LEHMANN, Hajo ,  LETINOIS, Ulla ,  MEDLOCK, Jonathan

IPC: C07C37/14 ,  C07C39/07

CPC classification number: C07C41/30 ,  C07C37/07 ,  C07C37/50 ,  C07C41/36 ,  C07C43/1783 ,  C07C46/08 ,  C07D311/72 ,  C07C50/02 ,  C07C39/08 ,  C07C39/07

Abstract: The present invention relates to a method of preparing ortho substituted phenols from 2,5-dimethylfuran and propargyl ethers in the presence of a gold(I) complex. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of said ortho substituted phenols.

Abstract translation: 本发明涉及在金（I）络合物存在下由2,5-二甲基呋喃和炔丙基醚制备邻位取代的苯酚的方法。 使用2,5-二甲基呋喃是特别有利的，因为这提供了所述邻位取代酚的生态学有益合成。

公开(公告)号：WO2015001029A1

公开(公告)日：2015-01-08

申请号：PCT/EP2014/064203

申请日：2014-07-03

Applicant: DSM IP ASSETS B.V.

Inventor： LETINOIS, Ulla ,  NETSCHER, Thomas

IPC: C07D311/22

CPC classification number: C07D311/22 ,  C07B2200/09

Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.

Abstract translation: 本发明涉及在苯并二氢吡喃酮或苯并二氢吡喃环中2-位的立体特异性物质中的色满酮或色烷的合成。 已经发现，在特定类型的式的手性化合物和至少一种苯酚或苯硫酚的存在下，该合成是特别有可能的。