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公开(公告)号:WO2021174475A1
公开(公告)日:2021-09-10
申请号:PCT/CN2020/077896
申请日:2020-03-05
申请人: GIVAUDAN SA , CHEN, Chun
发明人: COCITO ARMANINO, Nicolas , CHARPENTIER, Julie , DING, Changming , EMTER, Roger , NATSCH, Andreas , WANG, Chao , ZHOU, Lijun
IPC分类号: C07C62/04 , C07C229/34 , A61K31/12 , A61P43/00
摘要: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.
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公开(公告)号:WO2020120643A1
公开(公告)日:2020-06-18
申请号:PCT/EP2019/084773
申请日:2019-12-12
申请人: GIVAUDAN SA
发明人: LINIGER, Marc , NATSCH, Andreas
IPC分类号: C07D309/04 , A61K8/49
摘要: The present invention is concerned with fragrance ingredients and with fragrance preparations, for imparting desirable odor notes to consumer products, in particular it is concerned with (2S,4R)-4-methyl-2-((Z)-2-methylbut-1-en-1-yl)tetrahydro-2H-pyran that can be used as replacements for 4-methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H- pyran.
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公开(公告)号:WO2007071090A1
公开(公告)日:2007-06-28
申请号:PCT/CH2006/000708
申请日:2006-12-18
申请人: GIVAUDAN SA , NATSCH, Andreas
发明人: NATSCH, Andreas
CPC分类号: A61K8/37 , A61K8/33 , A61K8/368 , A61K2800/524 , A61K2800/59 , A61Q17/005
摘要: The invention is directed to personal care products and compositions that comprise at least one preservative compound selected from the group consisting of benzoic acid, p-hydroxy-benzoic acid, methyl-paraben, ethyl-paraben, propyl-paraben, isopropyl-paraben, butyl-paraben, isobutyl-paraben, benzyl-paraben, or a salt thereof, in a total concentration of 0.1 % to 0.5% (w/w); and at least one preservative enhancer compound selected from the group consisting of benzaldehyde, 4-methylbenzaldehyde, heliotropine, vanilline, 4-hydroxybenzaldehyde, 3-hydroxybenzaldehyde, 4-methoxybenzaldehyde, 3-methoxybenzaldehyde, 2,4-dihydroxybenzaldehyde, 3-hydroxy-4-methoxybenzaldehyde, 3,5-dihydroxybenzaldehyde, and 4-hydroxy-2-methoxybenzaldehyde, in a total concentration of 0.05 to 0.5% (w/w), in a cosmetically acceptable base. The composition optionally contains at least one compound selected from the group consisting of phenoxyethanol, 2-phenylethanol, and benzylalcohol, in a total concentration of 0.05 to 0.3 % (w/w), but does not contain other classic bactericidal, fungicidal, sporicidal or preservative compounds. The invention is further directed to methods of forming such compositions and products and the use of preservatives and preservative enhancers in such compositions and products.
摘要翻译: 本发明涉及个人护理产品和组合物,其包含至少一种选自苯甲酸,对羟基苯甲酸,对羟基苯甲酸甲酯,对羟基苯甲酸乙酯,对羟基苯甲酸丙酯,对羟基苯甲酸异丙酯,对羟基苯甲酸异丙酯, 对羟基苯甲酸酯,异丁基对羟基苯甲酸酯,对羟基苯甲酸苄酯或其盐,总浓度为0.1%至0.5%(w / w); 和至少一种选自苯甲醛,4-甲基苯甲醛,直链球蛋白,香草醛,4-羟基苯甲醛,3-羟基苯甲醛,4-甲氧基苯甲醛,3-甲氧基苯甲醛,2,4-二羟基苯甲醛,3-羟基-4 - 甲氧基苯甲醛,3,5-二羟基苯甲醛和4-羟基-2-甲氧基苯甲醛,总浓度为0.05-0.5%(w / w),在化妆品可接受的碱中。 该组合物任选地含有至少一种选自苯氧基乙醇,2-苯基乙醇和苄醇的化合物,其总浓度为0.05-0.3%(w / w),但不包含其它经典杀菌剂,杀真菌剂,杀孢子粉或 防腐剂。 本发明还涉及形成这种组合物和产品的方法以及在这种组合物和产品中使用防腐剂和防腐剂增强剂。
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公开(公告)号:WO2007071089A1
公开(公告)日:2007-06-28
申请号:PCT/CH2006/000707
申请日:2006-12-18
申请人: GIVAUDAN SA , NATSCH, Andreas
发明人: NATSCH, Andreas
CPC分类号: A61K8/33 , A61K8/34 , A61K2800/524 , A61K2800/59 , A61Q17/005
摘要: Provided are personal care products and compositions that comprise at least one preservative compound selected from the group consisting of phenoxyethanol, 2-phenyl ethanol, phenoxypropanol, 3-phenylpropanol and benzylalcohol, in a total concentration of 0.1 to 1% (w/w); and at least one preservative enhancer compound selected from the group consisting of 4-methylbenzaldehyde, heliotropine, vanilline, 4-hydroxybenzaldehye, 3-hydroxybenzaldehyde, 4-methoxybenzaldehyde, 3-methoxybenzaldehyde, 2, 4-dihydroxybenzaldehyde, 3-hydroxy-4-methoxybenzaldehyde, 3, 5-dihydroxybenzaldehyde, and 4-hydroxy-2-methoxybenzaldehyde, in a total concentration of 0.05 to 0.5% (w/w), in a cosmetically acceptable base. The composition does not contain certain classic bactericidal, fungicidal, sporicidal or preservative compounds. Further provided are methods of forming such compositions and products and the use of preservatives and preservative enhancers in such compositions and products.
摘要翻译: 本发明提供了总量为0.1〜1%(w / w)的至少一种选自苯氧基乙醇,2-苯基乙醇,苯氧基丙醇,3-苯基丙醇和苄醇的防腐剂化合物的个人护理产品和组合物。 和至少一种选自4-甲基苯甲醛,直链球蛋白,香草醛,4-羟基苯甲醛,3-羟基苯甲醛,4-甲氧基苯甲醛,3-甲氧基苯甲醛,2,4-二羟基苯甲醛,3-羟基-4-甲氧基苯甲醛的防腐增强剂化合物 ,5,5-二羟基苯甲醛和4-羟基-2-甲氧基苯甲醛,总浓度为0.05-0.5%(w / w),在化妆品可接受的碱中。 该组合物不含有某些经典的杀菌,杀真菌,杀孢子或防腐剂。 还提供了形成这种组合物和产品的方法以及在这种组合物和产品中使用防腐剂和防腐剂增强剂。
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公开(公告)号:WO2021102896A1
公开(公告)日:2021-06-03
申请号:PCT/CN2019/121927
申请日:2019-11-29
申请人: GIVAUDAN SA , WANG, Chao
发明人: COCITO ARMANINO, Nicolas , CHARPENTIER, Julie , CHEN, Chun , EMTER, Roger , GOEKE, Andreas , HUANG, Feng , NATSCH, Andreas , ZHOU, Lijun , ZOU, Yue
IPC分类号: C07D261/20 , C07D265/34 , A61K31/423 , A23L33/10
摘要: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.
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公开(公告)号:WO2021074281A1
公开(公告)日:2021-04-22
申请号:PCT/EP2020/079009
申请日:2020-10-15
申请人: GIVAUDAN SA
发明人: COCITO ARMANINO, Nicolas , BOMBRUN, Agnes , CHAI, An , CHARPENTIER, Julie , CHEN, Chun , EMTER, Roger , MATHYS, Marion , NATSCH, Andreas , WANG, Chao , ZHOU, Lijun
IPC分类号: C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , A61P25/00 , A61P29/00 , A61P43/00 , A61K8/49 , A61K31/454 , A61Q11/00
摘要: Disclosed are TRPM8 modulators as defined by formula (I) for achieving a cooling effect on skin and mucousa.
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公开(公告)号:WO2016074697A1
公开(公告)日:2016-05-19
申请号:PCT/EP2014/074179
申请日:2014-11-10
申请人: GIVAUDAN SA
发明人: GOEKE, Andreas , LAUE, Heike , NATSCH, Andreas , VOIROL, Francis
IPC分类号: C11B9/00 , C07C47/228
CPC分类号: C11B9/0061 , A61K8/33 , A61Q13/00 , C07C47/228 , C11B9/003 , C11D3/50 , C11D3/507
摘要: The use of a compound represented by the formula I wherein R 1 through R 4 is independently H or methyl; and R 6 is a branched or linear, saturated or unsaturated C 3 -C 7 alkyl, alkenyl, cycloalkyl or cycloalkenyl residue, as perfume ingredients in personal care and household care products.
摘要翻译: 使用由式I表示的化合物,其中R 1至R 4独立地为H或甲基; 作为个人护理和家庭护理产品中的香料成分,R 6是支链或直链,饱和或不饱和的C 3 -C 7烷基,链烯基,环烷基或环烯基残基。
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公开(公告)号:WO2007025402A1
公开(公告)日:2007-03-08
申请号:PCT/CH2006/000460
申请日:2006-08-24
申请人: GIVAUDAN SA , NATSCH, Andreas , MORAES, Eduardo
发明人: NATSCH, Andreas , MORAES, Eduardo
摘要: The invention relates to hedonistically pleasing oral malodour counteracting compositions including flavour compositions and oral care products, methods to form such compositions and methods to counteract oral malodour. The compositions comprises 2 or more of oral malodour counteracting actives of formula I in a total concentration of at least 10% (w/w) based on the total concentration of flavour ingredients, and an individual concentration of 1% or more per oral malodour counteractant, based on total flavour ingredients. The maximum concentration of any individual oral malodour counteracting active based on the total of oral malodour counteracting actives is 70%. The identified oral malodour counteracting actives are various flavour compounds and natural ingredients.
摘要翻译: 本发明涉及享乐主义的令人愉悦的口服恶臭反作用组合物,包括风味组合物和口腔护理产品,形成这种组合物的方法和抵消口腔恶臭的方法。 组合物包含基于风味成分的总浓度至少10%(w / w)的总浓度的式I的口服恶臭反作用活性物质,以及每口服恶臭对抗剂1%或更多的个体浓度 ,基于总风味成分。 基于口服恶臭反作用活性物质的总量,任何个别口服恶臭反作用活性物质的最大浓度为70%。 鉴定的口服恶臭反应活性物质是各种风味化合物和天然成分。
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公开(公告)号:WO2006102777A1
公开(公告)日:2006-10-05
申请号:PCT/CH2006/000161
申请日:2006-03-17
申请人: GIVAUDAN SA , NATSCH, Andreas , WASESCHA, Michael
发明人: NATSCH, Andreas , WASESCHA, Michael
CPC分类号: A61K8/34 , A61K8/33 , A61K8/347 , A61K8/35 , A61K8/40 , A61K8/411 , A61K8/4973 , A61K8/498 , A61Q13/00 , A61Q19/02
摘要: The invention relates to methods of cosmetic lightening the human skin, compounds and perfume compositions that have a skin lightening effect and personal care products for application to the human skin comprising such skin lightening compounds and perfume compositions. A number of compounds not known before to have a skin lightening effect were identified. These skin lightening compounds provide the perfumer with a larger palette of fragrance notes and provide more possibilities to create desired fragrance accords in skin lightening perfume compositions and skin lightening personal care products. Skin lightening perfume compositions and skin lightening personal care products according to the invention comprise at least one of the identified fragrant skin lightening compounds.
摘要翻译: 本发明涉及化妆品化妆品的化妆品,其具有皮肤增亮效果的化妆品,化妆品和香料组合物以及用于人皮肤的个人护理产品,其包含这些皮肤增亮化合物和香料组合物。 鉴定了许多以前不知道具有皮肤增亮作用的化合物。 这些皮肤增亮化合物为香料师提供了更大的香味调色剂,并提供更多的可能性,以在皮肤增亮香水组合物和皮肤增亮个人护理产品中产生所需的香料。 根据本发明的皮肤增亮香水组合物和皮肤增亮个人护理产品包含至少一种所鉴定的香味皮肤发亮化合物。
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公开(公告)号:WO2006026876A1
公开(公告)日:2006-03-16
申请号:PCT/CH2005/000509
申请日:2005-08-31
申请人: GIVAUDAN SA , DERRER, Samuel , NATSCH, Andreas , TRAUPE, Bernd , STANG, Melanie
发明人: DERRER, Samuel , NATSCH, Andreas , TRAUPE, Bernd , STANG, Melanie
IPC分类号: C07C69/675 , C07C229/08 , A01N37/36 , A01N37/44
CPC分类号: A01N37/36 , A01N37/44 , A61K8/37 , A61K8/416 , A61Q15/00 , A61Q17/005 , C07C69/675 , C07C229/08
摘要: Ester compounds of the formula I-a wherein R 1 is selected from OH, NH 2 and NH 3 + X - , wherein X is an inorganic anion, wherein R 2 is a singly-branched saturated or unsaturated aliphatic hydrocarbon moiety selected from C 7 - C 15 , wherein R 5 is selected from H, and a linear saturated or unsaturated aliphatic hydrocarbon moiety selected from C 6 - C 14 , and wherein R 2 and R 5 together have a total of 7 to 15 carbon atoms; that are useful as antibacterial or antifungal compounds in consumer products.
摘要翻译: 式I-a的酯化合物,其中R 1选自OH,NH 2和NH 3,其中R 1选自OH,NH 2和NH 3,
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