中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

9 records (took 0.016 seconds)

    WIPE COATED WITH A BOTANICAL EMULSION HAVING ANITMICROBIAL PROPERTIES
    1.
    发明申请
    WIPE COATED WITH A BOTANICAL EMULSION HAVING ANITMICROBIAL PROPERTIES 审中-公开
    用具有抗微生物特性的植物乳液涂布的擦拭物

    公开(公告)号：WO2012077001A2

    公开(公告)日：2012-06-14

    申请号：PCT/IB2011054787

    申请日：2011-10-26

    Applicant: KIMBERLY CLARK CO ,  LEE JAEHONG ,  TOPOLKARAEV VASILY A ,  KOENIG DAVID W ,  SCHOLL NEIL T ,  KIM YOUNGSOOK ,  WANG JAMES H

    Inventor： LEE JAEHONG ,  TOPOLKARAEV VASILY A ,  KOENIG DAVID W ,  SCHOLL NEIL T ,  KIM YOUNGSOOK ,  WANG JAMES H

    IPC: A01N25/34 ,  A01N65/00 ,  A01P1/00 ,  A47K7/02 ,  A47L13/17 ,  A61K9/70 ,  C09G1/04 ,  C11D17/04

    CPC classification number: A01N65/00 ,  A01N31/08 ,  A01N2300/00 ,  A01N25/04 ,  A01N25/10 ,  A01N25/22 ,  A01N25/34 ,  A01N65/22

    Abstract: An oil-in-water emulsion that is environmentally friendly and also exhibits antimicrobial activity is provided. More specifically, the oil phase of the emulsion includes a botanical oil derived from a plant (e.g., thymol, carvacrol, etc.). Because the botanical oil tends to leach out of the emulsion during storage and before it is used in the desired application, a water-dispersible polymer is also employed in the aqueous phase of the emulsion to enhance long term stability of the oil and, in turn, antimicrobial efficacy. Without intending to be limited by theory, it is believed that the water-dispersible polymer can effectively encapsulate the botanical oil within the emulsion and inhibit its premature release. Once the emulsion is formed, water can then be removed so that it becomes a substantially anhydrous concentrate. In this manner, the water-dispersible polymer will not generally disperse before use and prematurely release the botanical oil. When it is desired, moisture may simply be re-applied to the concentrate to disperse the polymer and activate the release of the botanical oil. Of course, to provide the optimum degree of biocompatibility, the water-dispersible polymer is also a "biopolymer" that is biodegradable and/or renewable.

    Abstract translation: 提供对环境友好并且还显示出抗微生物活性的水包油乳液。 更具体地说，乳剂的油相包括来源于植物的植物油（例如百里酚，香芹酚等）。 由于植物油倾向于在储存过程中以及在用于所需应用之前浸出乳液，因此在乳液的水相中也使用水分散性聚合物以增强油的长期稳定性，并且反过来 ，抗菌功效。 不受理论限制，认为水分散性聚合物可以有效地将植物油包封在乳液中并且抑制其过早释放。 一旦形成乳液，就可以除去水，使其变成基本上无水的浓缩物。 以这种方式，水分散性聚合物在使用前通常不会分散并过早地释放植物油。 当需要时，可以简单地将水分重新施加到浓缩物上以分散聚合物并激活植物油的释放。 当然，为了提供最佳的生物相容性，水分散性聚合物也是可生物降解和/或可再生的“生物聚合物”。

    MELT PROCESSED ANTIMICROBIAL COMPOSITION
    2.
    发明申请
    MELT PROCESSED ANTIMICROBIAL COMPOSITION 审中-公开
    熔融加工抗微生物组合物

    公开(公告)号：WO2012077002A2

    公开(公告)日：2012-06-14

    申请号：PCT/IB2011054828

    申请日：2011-10-31

    Applicant: KIMBERLY CLARK CO ,  WANG JAMES H ,  SHI BO ,  LEE JAEHONG ,  TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  KIM YOUNGSOOK

    Inventor： WANG JAMES H ,  SHI BO ,  LEE JAEHONG ,  TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  KIM YOUNGSOOK

    IPC: A01N65/00 ,  A01N43/04 ,  A01P1/00 ,  A61K31/70

    CPC classification number: A01N31/08 ,  A01N65/00 ,  B29B7/10 ,  B29B7/38 ,  B29B9/06 ,  B29B9/12 ,  B29B9/16 ,  B29C47/00 ,  B29C47/6087 ,  A01N25/10 ,  A01N25/12 ,  A01N25/28 ,  A01N25/34 ,  A01N2300/00 ,  A01N65/08 ,  A01N65/20 ,  A01N65/24 ,  A01N65/28 ,  A01N65/38

    Abstract: A method for forming a composition that includes mixing an antimicrobially active botanical oil (e.g., thymol, carvacrol, etc.) and a modified starch polymer within a melt blending device (e.g., extruder) is provided. Unlike the problems associated with proteins, the use of starch polymers allows for a greater degree of flexibility in the processing conditions and is still able to achieve good properties in the resulting composition. The present inventors have also discovered that a plasticizer may be employed to facilitate melt processing of the starch, as well as to enhance the ability of the botanical oil to flow into the internal structure of the starch where it can be retained in a stable manner. The composition is also typically generally free of solvents. In this manner, the starch will not generally disperse before use and prematurely release the botanical oil. Due to the water sensitivity of the modified starch, however, it may be subsequently dispersed by moisture when it is desired to release the botanical oil.

    Abstract translation: 提供了一种形成组合物的方法，其包括在熔融共混装置（例如挤出机）中混合抗微生物活性植物油（例如百里酚，香芹酚等）和改性淀粉聚合物。 与蛋白质相关的问题不同，淀粉聚合物的使用允许在加工条件下具有更大程度的柔性，并且仍能在所得组合物中获得良好的性能。 本发明人还发现，可以使用增塑剂来促进淀粉的熔融加工，以及提高植物油流入淀粉内部结构的能力，其中它可以以稳定的方式保留。 组合物通常通常也不含溶剂。 以这种方式，淀粉通常不会在使用前分散并且过早地释放植物油。 然而，由于改性淀粉的水敏感性，当需要释放植物油时，随后可以通过水分分散。

    PROTEIN STABILIZED ANTIMICROBIAL COMPOSITION FORMED BY MELT PROCESSING
    3.
    发明申请
    PROTEIN STABILIZED ANTIMICROBIAL COMPOSITION FORMED BY MELT PROCESSING 审中-公开
    熔融加工形成的蛋白质稳定抗菌组合物

    公开(公告)号：WO2012077006A2

    公开(公告)日：2012-06-14

    申请号：PCT/IB2011054839

    申请日：2011-10-31

    Applicant: KIMBERLY CLARK CO ,  TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  LEE JAEHONG ,  AMBROSE DIANNA L ,  KIM YOUNGSOOK

    Inventor： TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  LEE JAEHONG ,  AMBROSE DIANNA L ,  KIM YOUNGSOOK

    IPC: A01N65/00 ,  A01N25/02 ,  A01P1/00

    CPC classification number: A01N25/02 ,  A01N31/08 ,  A01N43/90 ,  A01N65/00 ,  B29B7/42 ,  B29C47/0004 ,  B29C47/0009 ,  B29C47/0021 ,  B29C47/0026 ,  B29C47/025 ,  B29C47/6056 ,  B29C47/92 ,  B29C2947/92514 ,  B29C2947/926 ,  B29C2947/92704 ,  B29C2947/92828 ,  B29C2947/92876 ,  A01N25/10 ,  A01N25/12 ,  A01N25/28 ,  A01N25/34 ,  A01N2300/00 ,  A01N65/20 ,  A01N65/22 ,  A01N65/44

    Abstract: A method for forming an antimicrobial composition that includes mixing an antimicrobially active botanical oil (e.g., thymol, carvacrol, etc.) and protein within a melt blending device (e.g., extruder) is provided. Despite the problems normally associated with melt processing proteins, the present inventors have discovered that the processing conditions and components may be selectively controlled to allow for the formation of a stable, melt-processed composition that is able to exhibit good mechanical properties. For example, the extrusion temperature(s) and shear rate employed during melt blending are relatively low to help limit polypeptide dissociation, thereby minimizing the impact of aggregation and embrittlement. While the use of such low temperature/shear conditions often tend to reduce mixing efficiency, the present inventors have discovered that a carrier fluid may be employed to enhance the ability of the botanical oil to flow into the internal structure of the protein where it can be retained in a stable manner. The composition is also typically anhydrous and generally free of solvents. In this manner, the protein will not generally disperse before use and prematurely release the botanical oil.

    Abstract translation: 提供了一种形成抗微生物组合物的方法，该方法包括在熔融共混装置（例如挤出机）内混合抗微生物活性植物油（例如百里酚，香芹酚等）和蛋白质。 尽管通常与熔融加工蛋白有关的问题，本发明人已经发现可以选择性地控制加工条件和组分，以形成能够表现出良好机械性能的稳定的熔融加工组合物。 例如，在熔融共混过程中使用的挤出温度和剪切速率相对较低以帮助限制多肽解离，从而使聚集和脆化的影响最小化。 尽管使用这种低温/剪切条件常常倾向于降低混合效率，但是本发明人已经发现载体流体可以用于增强植物油流入蛋白质内部结构中的能力，其中它可以是 保持稳定。 该组合物通常也是无水的并且通常不含溶剂。 以这种方式，蛋白质在使用前通常不会分散并且过早地释放植物油。

    DELIVERY SYSTEM FOR ACTIVE AGENTS
    4.
    发明申请
    DELIVERY SYSTEM FOR ACTIVE AGENTS 审中-公开
    主动代理的交付系统

    公开(公告)号：WO2015019211A4

    公开(公告)日：2015-04-09

    申请号：PCT/IB2014062975

    申请日：2014-07-09

    Applicant: KIMBERLY CLARK CO

    Inventor： TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  MCENEANY RYAN J ,  EBY THOMAS A

    IPC: A61K9/16 ,  A61K9/14 ,  A61K47/30

    CPC classification number: A61K9/70 ,  A61K9/0092 ,  A61K9/1647 ,  A61K9/1694 ,  A61K9/5015 ,  A61K9/7007 ,  A61L15/425 ,  A61L15/44 ,  A61L15/46 ,  A61L2400/12 ,  C08J5/18 ,  C08L67/04

    Abstract: A delivery system containing an active agent within a polymeric material formed from a thermoplastic composition is provided. Through selective control over the particular nature of the thermoplastic composition, as well as the manner in which it is formed, the present inventors have discovered that a porous network can be created that contains a plurality of micropores and nanopores. The ability to create such a multimodal pore size distribution can allow the delivery rate of an active agent to be tailored for a particular use.

    Abstract translation: 提供了一种在由热塑性组合物形成的聚合物材料内含有活性剂的递送系统。 通过对热塑性组合物的特定性质的选择性控制以及其形成方式，本发明人已经发现，可以产生包含多个微孔和纳米孔的多孔网络。 创建这种多峰孔径分布的能力可以允许活性剂的输送速率针对特定用途进行定制。

    RENEWABLE POLYESTER FIBERS HAVING A LOW DENSITY
    5.
    发明申请
    RENEWABLE POLYESTER FIBERS HAVING A LOW DENSITY 审中-公开
    具有低密度的可再生聚酯纤维

    公开(公告)号：WO2013118019A2

    公开(公告)日：2013-08-15

    申请号：PCT/IB2013050729

    申请日：2013-01-28

    Applicant: KIMBERLY CLARK CO

    Inventor： MCENEANY RYAN J ,  TOPOLKARAEV VASILY A ,  SCHOLL NEIL T ,  EBY TOM

    IPC: D01F6/62 ,  D01D5/08 ,  D01F1/10 ,  D01F6/92 ,  D04H1/435 ,  D04H1/724

    CPC classification number: D01F6/92 ,  B29C47/0004 ,  B29C47/0011 ,  B29C47/0014 ,  B29C47/0057 ,  B29C47/30 ,  B29C47/802 ,  B29C47/8815 ,  B29C2947/92704 ,  D01D5/12 ,  D01D5/247 ,  D01F1/10 ,  D04H3/16 ,  Y10T428/2913 ,  Y10T442/608

    Abstract: Fibers that are formed from a thermoplastic composition that contains a rigid renewable polyester and has a voided structure and low density are provided. To achieve such a structure, the renewable polyester is blended with a polymeric toughening additive in which the toughening additive can be dispersed as discrete physical domains within a continuous matrix of the renewable polyester. Fibers are thereafter formed and then stretched or drawn at a temperature below the glass transition temperature of the polyester (i.e., "cold drawn"). Without intending to be limited by theory, the present inventors believe that the deformation force and elongational strain of the drawing process causes debonding to occur in the renewable polyester matrix at those areas located adjacent to the discrete domains. This creates a network of voids (e.g., micro-voids, nano-voids, or a combination thereof) located adjacent to the discrete domains, which as a result of their proximal location, can form a bridge between the boundaries of the voids and act as internal structural "hinges" that help stabilize the network and increase its ability to dissipate energy.

    Abstract translation: 提供由含有刚性可再生聚酯并且具有空隙结构和低密度的热塑性组合物形成的纤维。 为了实现这种结构，可再生聚酯与聚合增韧添加剂共混，其中增韧添加剂可以作为可再生聚酯的连续基质中的离散物理区域分散。 之后形成纤维，然后在低于聚酯的玻璃化转变温度的温度（即“冷拉伸”）下拉伸或拉伸。 不意在受理论的限制，本发明人认为拉伸过程的变形力和拉伸应变导致在可再生聚酯基体中在离散区域附近的那些区域发生剥离。 这产生了位于邻近离散区域的空隙网络（例如，微空隙，纳米空隙或其组合），由于它们的近端位置，它们可以在空隙的边界和作用之间形成桥梁 作为有助于稳定网络并增加其消耗能量的能力的内部结构“铰链”。

    MELT-BLENDED PROTEIN COMPOSITION
    9.
    发明申请
    MELT-BLENDED PROTEIN COMPOSITION 审中-公开
    融合蛋白组合物

    公开(公告)号：WO2012077005A2

    公开(公告)日：2012-06-14

    申请号：PCT/IB2011054838

    申请日：2011-10-31

    Applicant: KIMBERLY CLARK CO ,  TOPOLKARAEV VASILY A ,  SCHOLL NEIL T

    Inventor： TOPOLKARAEV VASILY A ,  SCHOLL NEIL T

    IPC: C08L89/00 ,  C08B1/00 ,  C08K5/05 ,  C08K5/09 ,  C08L33/00

    CPC classification number: A61K47/42 ,  A01N25/28 ,  A61K8/0208 ,  A61K8/645 ,  A61Q17/005 ,  A61Q19/10 ,  C08K5/0016 ,  C08K5/0025 ,  C08K5/053 ,  C08K5/09 ,  C08K5/1515 ,  C08L89/00 ,  A01N25/10 ,  A01N65/00

    Abstract: A melt-processed protein composition formed from a protein, plasticizer, and an electrophilic reagent is provided. The electrophilic reagent, for instance, may be selected to undergo a nucleophilic addition reaction with free sulfhydryl and/or thiyl radicals to help minimize the formation of disulfide crosslinking bonds that could otherwise lead to protein aggregation during melt processing. To enhance the degree to which the electrophilic reagent can limit crosslinking, a plasticizer is also employed that helps to mediate the adsorption of the electrophilic reagent into the internal structure of the protein, where it can be more stably retained. Furthermore, the temperature and shear rate employed during melt blending may also be selected to be relatively low to help limit polypeptide dissociation, thereby minimizing the impact of aggregation and embrittlement.

    Abstract translation: 提供由蛋白质，增塑剂和亲电子试剂形成的熔融加工的蛋白质组合物。 例如，可以选择亲电子试剂以进行与游离巯基和/或硫酰基的亲核加成反应，以帮助最小化二硫化物交联键的形成，否则所述二硫键会在熔融加工期间导致蛋白质聚集。 为了提高亲电子试剂限制交联的程度，还使用增塑剂，其帮助介导亲电试剂吸附到蛋白质的内部结构中，在那里它可以更稳定地保留。 此外，熔融共混过程中使用的温度和剪切速率也可以选择为相对较低，以帮助限制多肽解离，从而使聚集和脆化的影响最小化。

Patent Agency Ranking