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公开(公告)号：WO2013049702A3
公开(公告)日：2013-10-10
申请号：PCT/US2012058096
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
CPC classification number: C12Q1/686 , B01L3/50855 , B01L3/50857 , B01L7/52 , B01L2200/023 , B01L2200/025 , B01L2200/028 , B01L2200/143 , B01L2300/021 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/1827 , B01L2300/1844
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样本保持器中的任何一个的可互换组件，每个相应样本保持器被配置为接收多个样本。 该系统还包括配置成循环多个样品通过一系列温度的控制系统。 该系统还包括配置成检测从多个样品发射的荧光信号的光学系统。 该光学系统尤其可以包括单个场透镜，激励源，光学传感器和多个滤波器组件。 激发源可以是一个或多个发光二极管。 场镜可以是双凸透镜。
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公开(公告)号：WO2014130970A3
公开(公告)日：2015-12-03
申请号：PCT/US2014018110
申请日：2014-02-24
Applicant: LIFE TECHNOLOGIES CORP
Inventor： CHEN MINGSONG , AGUANNO MAURO , BOO KUAN MOON , SOH WOON LIANG TERENCE , FREUDENTHAL JACOB , MARKS JEFFREY
CPC classification number: G01N21/6486 , G01N21/0332 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2201/061 , G01N2201/0624 , G01N2201/0627 , G01N2201/121
Abstract: An instrument for processing and/or measuring a biological process contains a sample processing system, an excitation source, an excitation optical system, an optical sensor, and an emission optical system. The sample processing system is configured to retain a first sample holder and a second sample holder, wherein the number of sample cells is different for each sample holder or a characteristic dimension for the first sample cells is different from that of the second sample holder. The instrument also includes an excitation source temperature controller comprising a temperature sensor that is coupled to the excitation source. The temperature controller is configured to produce a first target temperature when the first sample holder is retained by the instrument and to produce a second target temperature when the second sample holder is retained by the instrument.
Abstract translation: 用于处理和/或测量生物过程的仪器包括样品处理系统，激发源，激发光学系统，光学传感器和发射光学系统。 样品处理系统被配置为保持第一样品保持器和第二样品保持器，其中样品池的数量对于每个样品保持器是不同的，或者第一样品池的特征尺寸与第二样品保持器的特征尺寸不同。 仪器还包括激发源温度控制器，其包括耦合到激发源的温度传感器。 温度控制器被配置为当第一样品保持器被仪器保持时产生第一目标温度，并且当第二样品保持器被仪器保持时产生第二目标温度。
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公开(公告)号：WO2016127107A3
公开(公告)日：2016-11-03
申请号：PCT/US2016016856
申请日：2016-02-05
Applicant: LIFE TECHNOLOGIES CORP
Inventor： CHU YONG , MARKS JEFFREY , FREUDENTHAL JACOB , CHEN MINGSONG , TOH TIONG HAN , AGUANNO MAURO , LAU LIK SENG , LOH LIAN SENG , TEO KOK SIONG , CHU ZENG WEI , MATHERS XIN , UY MICHAEL , YEO HUEI STEVEN , BOO KUAN MOON , LEE WAY XUANG , KOO CHIN YONG , TEO WEI FUH , LAU SOO YONG , SHIN HON SIU , TAN ZEQI , WESSEL THOMAS , WOO DAVID
CPC classification number: B01L7/52 , B01L2200/145 , B01L2300/18 , B01L2300/1822 , C12Q1/6806 , G01N21/274 , G01N21/6452 , G01N21/6486 , G01N35/026 , G01N2021/6439 , G01N2035/00316 , G01N2035/00366 , G01N2201/061 , G01N2201/12
Abstract: A biological analysis system (100) is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block (114) configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray (160) comprising a slide assembly, the tray (160) configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.
Abstract translation: 提供生物分析系统（100）。 该系统包括样品块组件。 样品块组件包括被配置为容纳样品架的样品块（114），样品保持器被配置为接收多个样品。 该系统还包括配置成使多个样品循环通过一系列温度的控制系统。 所述系统还包括自动托盘（160），其包括滑动组件，所述托盘（160）构造成可将样品块组件从关闭位置可逆地滑动到打开位置，以允许用户接近所述多个样品保持器。
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公开(公告)号：WO2013049702A2
公开(公告)日：2013-04-04
申请号：PCT/US2012058096
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
CPC classification number: C12Q1/686 , B01L3/50855 , B01L3/50857 , B01L7/52 , B01L2200/023 , B01L2200/025 , B01L2200/028 , B01L2200/143 , B01L2300/021 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/1827 , B01L2300/1844
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样品保持器中的任何一个的可互换组件，每个样品保持器被配置为接收多个样品。 该系统还包括被配置为使多个样品循环通过一系列温度的控制系统。 该系统还包括被配置为检测从多个样本发射的荧光信号的光学系统。 特别地，光学系统可以包括单个场透镜，激发源，光学传感器和多个滤光器组件。 激发源可以是一个或多个发光二极管。 场透镜可以是双凸透镜。
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