Abstract:
This disclosure relates generally to a sampling device, and, more particularly, a sampling device that facilitates spectroscopic measurements with a variable path length and the necessary software controlled algorithms, and methods for using such a device.
Abstract:
A sensor that determines information related to a gaseous analyte in a body of fluid. The sensor comprises an emitter, a luminescable medium, a radiation sensor, and a processor. The emitter emits electromagnetic radiation having an oscillating intensity. The luminescable medium communicates with the body of fluid and emits luminescent radiation in response to the received electromagnetic radiation. The radiation sensor receives the luminescent radiation, and generates an output signal based on the intensity of the received luminescent radiation. The processor samples the output signal generated by the radiation sensor at two or more predetermined periodic points over the oscillation of the intensity of the electromagnetic radiation to determine information from the samples related to a phase difference between the oscillation of the intensity of the electromagnetic radiation emitted by the emitter and oscillation of the intensity of the luminescent radiation received by the radiation sensor.
Abstract:
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset contribution, photo response non-uniformity, and spurious charge contribution can be determined by the methods for the present teachings and used for signal correction by systems of the present teachings.
Abstract:
A system and method for characterizing contributions to signal noise associated with charge-coupled devices adapted for use in biological analysis. Dark current contribution, readout offset contribution, photo response non-uniformity, and spurious charge contribution can be determined by the methods for the present teachings and used for signal correction by systems of the present teachings.
Abstract:
A system for obtaining a measurement of a species of interest. The system includes one or more reference regions, a sensor region, an exciter unit, a detector unit and a processing unit. The exciter unit exposes first and second chemical transducers in the reference and sensor regions, respectively, to an excitation light while they are exposed to reference environments and an analyte, respectively. The detector unit measures responses of the first and the second chemical transducers to the excitation light. The processing unit determines a compensation for aging of the first chemical transducer from a discrepancy between the measurements of the responses of the first chemical transducer and reference responses. The processing unit applies the compensation for aging to the measurement of the response of the second chemical transducer to obtain the measurement of the species of interest in the analyte.
Abstract:
Beschrieben und dargestellt ist ein Sensor (1) zur Detektion der Konzentration wenigstens eines Mediums, insbesondere ein Nichtdispersiver Infrarotsensor (NDIR-Sensor), mit einer Strahlungsquelle (2) zur Aussendung elektromagnetischer Strahlung, insbesondere im infraroten Spektralbereich, mit einem über eine optische Weglänge mit einer Strahlungsquelle (2) im Wirkzusammenhang stehenden Detektor (3) zur Detektion der Intensität der auf den Detektor (3) fallenden Strahlung und mit einer Recheneinheit (4), wobei die Strahlungsquelle (2) eine lageabhängige Abstrahlcharakteristik aufweist, wobei der Detektor (3) wenigstens einen lageabhängigen Intensitätsmesswert an die Recheneinheit (4) zur weiteren Verarbeitung übermittelt und aus dem Intensitätsmesswert ein Konzentrationswert für das Medium ermittelt und ausgegeben wird. Ein Sensor (1) mit einer erhöhten Messgenauigkeit wird dadurch erzielt, dass in der Recheneinheit (4) die Lage des Sensors (1) beschreibende Lageinformationen abgelegt sind und die Recheneinheit (4) im Betriebszustand mittels einer die Lageinformationen berücksichtigenden Rechenvorschrift den lageabhängigen Intensitätsmesswert I 1 korrigiert und mit einem korrigierten Intensitätsmesswert I korr einen korrigierten Konzentrationswert K korr für das Medium ermittelt. Die Lageinformation kann mit einem Beschleunigungssensor (5) ermittelt werden. Ferner ist ein Verfahren zum Betreiben eines Sensors (1) zur Detektion einer Konzentration wenigstens eines Mediums beschrieben.
Abstract:
Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.
Abstract:
An instrument for processing and/or measuring a biological process contains a sample processing system, an excitation source, an excitation optical system, an optical sensor, and an emission optical system. The sample processing system is configured to retain a first sample holder and a second sample holder, wherein the number of sample cells is different for each sample holder or a characteristic dimension for the first sample cells is different from that of the second sample holder. The instrument also includes an excitation source temperature controller comprising a temperature sensor that is coupled to the excitation source. The temperature controller is configured to produce a first target temperature when the first sample holder is retained by the instrument and to produce a second target temperature when the second sample holder is retained by the instrument.
Abstract:
Disclosed herein is a process and system to correct reflective distortions of an optical spectrum. In addition, a spectroscopy system that compensates for reflective distortions is disclosed.
Abstract:
Die Erfindung bezieht sich auf ein Verfahren zur Ermittlung eines Formkorrekturwertes F für Labor-Flüssigkeitsanalyse-Küvetten (10) mit einem im Querschnitt kreisrunden Kuvettenkörper (12) für die fotometrische Flüssigkeitsanalyse, und sieht folgende Verfahrensschritte vor: optisches Messen des Innen- oder Außen-Durchmessers d 1 ;d 0 des Küvettenkörpers (12), Errechnen eines Formkorrekturwertes F aus dem vermessenen Küvettenkörper- Durchmesser d 1 ;d 0 , und Hinterlegung des Formkorrekturwertes F an dem Küvettenkörper (12).