Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.
Abstract:
A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to a channel void volume, a volume of a sample feed reservoir and a volume of the feed sample. In another embodiment, the separation module includes two reservoirs and a hydrophobic vent. The single- pass process provides high conversion while operating with relatively low pressure sources.
Abstract:
Electrodeionization apparatus (10) for the purification of water including a cathode (12), an anode (14), a plurality of alternating cation and anion permeable membranes (16, 18) that define concentrating and diluting flow channels (22, 20) between adjacent membrane pairs. The diluting channels include cation and anion exchange materials (24) fixed in close contact position to provide conductive paths for ions of the adjacent membranes and flow passages for water between the material. The packing material can include one or more macrostructural elements made of smaller microstructural elements. First and second stages can be used to purify water including calcium, carbon dioxide, and its hydrates, wherein the ion exchange material differs in the diluting flow channel of each stage, and the concentrating flow channels can include a brine channel between two guard channels.
Abstract:
An ocular implant device (10) that is insertable into either the anterior or posterior chamber of the eye to drain aqueous humor and/or to introduce medications. The implant can include a substantially cylindrical body (14) with a channel member that regulates the flow rate of aqueous humor from the anterior chamber or introduces medications into the posterior chamber, and simultaneously minimizes the ingress of microorganisms into the eye.