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    SYSTEMS FOR DELIVERING AND DEPLOYING AN ARTIFICIAL HEART VALVE WITHIN THE MITRAL ANNULUS
    1.
    发明申请
    SYSTEMS FOR DELIVERING AND DEPLOYING AN ARTIFICIAL HEART VALVE WITHIN THE MITRAL ANNULUS 审中-公开
    用于在MITRAL ANNULUS内提供和部署人造心脏瓣膜的系统

    公开(公告)号：WO2018067788A1

    公开(公告)日：2018-04-12

    申请号：PCT/US2017/055282

    申请日：2017-10-05

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    IPC: A61B17/00 ,  A61F2/24 ,  A61M25/00 ,  A61M25/01

    Abstract: The present disclosure describes devices, systems, and methods for loading, delivering, positioning, and deploying an artificial heart valve device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. The valve device is attached at the distal end of the delivery member, and is constrained within a valve cover of an outer sheath. A delivery catheter is configured to advance the valve relative to the outer sheath, and a suture catheter includes sutures/tethers which maintain proximal tension on the valve prior to deployment.

    Abstract translation: 本公开描述了用于在二尖瓣环处加载，递送，定位和部署人造心脏瓣膜装置的装置，系统和方法。 递送系统包括递送构件，递送构件联接到手柄组件并且从手柄组件向远侧延伸。 阀装置附接在输送构件的远端处，并被约束在外部护套的阀盖内。 输送导管被构造成相对于外鞘推进瓣膜，并且缝合导管包括在展开前保持瓣膜上的近端张力的缝合线/系绳。

    MECHANICAL INTERLOCK FOR CATHETERS
    4.
    发明申请
    MECHANICAL INTERLOCK FOR CATHETERS 审中-公开
    用于导管的机械联锁

    公开(公告)号：WO2018023045A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044461

    申请日：2017-07-28

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    IPC: A61M25/01 ,  A61F2/24 ,  A61B17/00 ,  A61M25/00

    Abstract: An intravascular device delivery system (100) has an elongated member (102) with a flexible hypotube (114). The hypotube can be rotationally keyed to a steerable catheter (116). The flexible hypotube includes one or more cuts (134, 136) to allow bending of the flexible hypotube within a first plane. The steerable catheter is steerable to bend the flexible hypotube within the first plane, and longitudinally movable relative to the flexible hypotube to allow distal movement of the steerable catheter relative to a distal end of the flexible hypotube.

    Abstract translation: 血管内装置输送系统（100）具有带有柔性海波管（114）的细长构件（102）。 海波管可旋转地键入可控导管（116）。 柔性海波管包括一个或多个切口（134,136），以允许柔性海波管在第一平面内弯曲。 可操纵导管可操纵以在第一平面内弯曲柔性海波管，并且可相对于柔性海波管纵向移动，以允许可操纵导管相对于柔性海波管的远端向远侧运动。

    COMBINATION STEERABLE CATHETER AND SYSTEMS
    5.
    发明申请
    COMBINATION STEERABLE CATHETER AND SYSTEMS 审中-公开
    组合式可控导管和系统

    公开(公告)号：WO2018023044A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044460

    申请日：2017-07-28

    Applicant: MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  VON OEPEN, Randolf

    Inventor： MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  VON OEPEN, Randolf

    IPC: A61F2/24

    Abstract: A steerable catheter has a body with an outer surface and an inner surface defining a central lumen. The outer surface and inner surface define a wall of the body, which has a plurality of steering lumen and control lumen extending longitudinally therethrough. The body includes a body material. The steering lumen and control lumen have a control lumen lining and steering lumen lining, respectively, with a higher durometer than the body material. A steering wire is positioned within the steering lumen and a control wire is positioned within the control lumen.

    Abstract translation: 可操纵导管具有主体，该主体具有限定中央内腔的外表面和内表面。 外表面和内表面限定了本体的壁，该壁具有多个纵向延伸穿过其中的控制内腔和控制内腔。 身体包括身体材料。 转向腔和控制腔分别具有控制腔内衬和转向腔内衬，其硬度比主体材料高。 转向线位于转向腔内，控制线位于控制腔内。

    SYSTEMS AND METHODS FOR LOADING AND DEPLOYING AN INTRAVASCULAR DEVICE
    6.
    发明申请
    SYSTEMS AND METHODS FOR LOADING AND DEPLOYING AN INTRAVASCULAR DEVICE 审中-公开
    用于加载和部署血管内装置的系统和方法

    公开(公告)号：WO2018044447A1

    公开(公告)日：2018-03-08

    申请号：PCT/US2017/044466

    申请日：2017-07-28

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  SALVADOR, Ken C. ,  XIE, Yongjin

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco ,  SALVADOR, Ken C. ,  XIE, Yongjin

    IPC: A61F2/24

    Abstract: An intravascular device delivery system includes an elongated member with a distal end cap and a delivery disc that are longitudinally movable using a disc handle. A main body of the disc handle is configured to move the distal end cap and a movable body of the disc handle is configured to move the delivery disc. The movable body is movable relative to the main body, and the main body and movable body are movable together.

    Abstract translation: 血管内装置输送系统包括具有远端盖和输送盘的细长构件，所述远端盖和输送盘可使用盘手柄纵向移动。 盘手柄的主体构造成移动远端帽，并且盘手柄的可移动主体构造成移动递送盘。 可移动体可相对于主体移动，并且主体和可移动体可一起移动。

    SYSTEMS AND METHODS FOR DELIVERING AN INTRAVASCULAR DEVICE TO THE MITRAL ANNULUS
    7.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING AN INTRAVASCULAR DEVICE TO THE MITRAL ANNULUS 审中-公开
    用于向MITRAL ANNULUS输送引导装置的系统和方法

    公开(公告)号：WO2018023052A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044481

    申请日：2017-07-28

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    IPC: A61M25/01 ,  A61M25/00 ,  A61F2/24 ,  A61F2/95

    Abstract: The present disclosure describes devices, systems, and methods for intravascularly delivering an implantable device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. The intravascular device is attached at the distal end of the delivery member, and is housed within a distal piece of an outer sheath. A steering catheter is nested within the outer sheath to bend the delivery member into position. A delivery catheter is configured to advance the intravascular device relative to the outer sheath, and a suture catheter includes sutures/tethers which may be coupled to the intravascular device prior to deployment.

    Abstract translation: 本公开描述了用于在二尖瓣环处血管内递送可植入装置的装置，系统和方法。 递送系统包括递送构件，递送构件联接到手柄组件并且从手柄组件向远侧延伸。 血管内装置附接在递送构件的远端处，并容纳在外部护套的远侧件内。 转向导管嵌套在外护套内以将输送构件弯曲到位。 输送导管被构造成使血管内装置相对于外鞘推进，并且缝合导管包括缝合线/系绳，该缝合线/系绳可以在展开之前联接到血管内装置。

    INTRAVASCULAR DEVICE DELIVERY SHEATH
    8.
    发明申请
    INTRAVASCULAR DEVICE DELIVERY SHEATH 审中-公开
    血管内装置递送鞘

    公开(公告)号：WO2018023038A1

    公开(公告)日：2018-02-01

    申请号：PCT/US2017/044446

    申请日：2017-07-28

    Applicant: MCNIVEN, Sean A. ,  VON OEPEN, Randolf ,  XIE, Yongjin ,  VALENCIA, Francisco ,  SALVADOR, Ken C.

    Inventor： MCNIVEN, Sean A. ,  VON OEPEN, Randolf ,  XIE, Yongjin ,  VALENCIA, Francisco ,  SALVADOR, Ken C.

    IPC: A61M25/01 ,  A61F2/966

    Abstract: An intravascular delivery system includes a delivery sheath capable of transmitting a predetermined tension or compression force in a longitudinal direction while maintaining flexibility to navigate tortuous anatomy. A method of delivering a medical device includes inserting an intravascular device delivery system including a delivery sheath having a continuous spine into a bodily lumen. A distal longitudinal force is applied to the delivery sheath. The distal force is transmitted through the continuous spine and across one or more slit cuts of the delivery sheath. A proximal longitudinal force is applied to the delivery sheath. The proximal longitudinal force is transmitted through the continuous spine of the delivery sheath.

    Abstract translation: 血管内递送系统包括递送护套，该递送护套能够沿纵向传递预定的张力或压缩力，同时保持灵活性以导航曲折的解剖结构。 递送医疗装置的方法包括将包括具有连续脊柱的递送鞘管的血管内装置递送系统插入到体腔中。 远端的纵向力施加到递送护套。 远侧力传递通过连续的脊柱并穿过输送鞘的一个或多个狭缝切口。 近端纵向力施加到递送护套。 近端纵向力通过输送套管的连续脊柱传输。

    METHODS, SYSTEMS, AND DEVICES FOR SEALING AND FLUSHING A DELIVERY SYSTEM
    10.
    发明申请
    METHODS, SYSTEMS, AND DEVICES FOR SEALING AND FLUSHING A DELIVERY SYSTEM 审中-公开
    用于密封和冲洗输送系统的方法，系统和设备

    公开(公告)号：WO2018044450A1

    公开(公告)日：2018-03-08

    申请号：PCT/US2017/044484

    申请日：2017-07-28

    Applicant: VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    Inventor： VON OEPEN, Randolf ,  MCNIVEN, Sean A. ,  VALENCIA, Francisco

    IPC: A61F2/95 ,  A61F2/24 ,  A61B90/70

    Abstract: A method for sealing and flushing a delivery member (104) includes sealing one or more lumens (126) and flushing air from the one or more lumens (126). An interventional device delivery system includes a handle assembly (102) and a delivery member (104). The handle assembly (102) includes a catheter holder with a passageway therethrough. A flush block (154) is associated with the catheter holder (128) and has a flush port (150) and a flush chamber (160). The delivery member (104) is associated with the handle assembly (102) and includes a plurality of catheters. At least one of the catheters has a proximal end disposed within the passageway in the catheter holder (128) and is in fluid communication with the flush chamber (160).

    Abstract translation: 用于密封和冲洗输送构件（104）的方法包括密封一个或多个管腔（126）并冲洗来自一个或多个管腔（126）的空气。 介入装置输送系统包括手柄组件（102）和输送构件（104）。 手柄组件（102）包括具有穿过其中的通道的导管保持器。 冲洗块（154）与导管支架（128）相关联并具有冲洗口（150）和冲洗室（1​​60）。 输送构件（104）与手柄组件（102）相关联并且包括多个导管。 导管中的至少一个导管具有布置在导管保持器（128）中的通道内的近端并且与冲洗室（1​​60）流体连通。

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