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    ADMINISTRATION OF GLUCOCORTICOID STEROIDS TO LIVESTOCK
    1.
    发明申请
    ADMINISTRATION OF GLUCOCORTICOID STEROIDS TO LIVESTOCK 审中-公开
    葡萄球菌甾体对畜牧业的管理

    公开(公告)号：WO2016168239A1

    公开(公告)日：2016-10-20

    申请号：PCT/US2016/027199

    申请日：2016-04-13

    申请人： ANIMAL BIOTECH, LLC

    发明人： MCGLONE, John, J.

    IPC分类号： A61K31/573 ,  A01K67/02

    CPC分类号： A61K31/573 ,  A23K20/168 ,  A23K50/30 ,  A23K50/60

    摘要： There is provided a method of treating a weaning piglet with a cortisol agonist where the method includes administering a dose of the cortisol agonist to the weaning piglet, in a therapeutically effective amount, to cause an increase in body mass as compared to a like weaning but untreated piglet. The cortisol agonist may be dexamethasone. Further, the dose may range from about 0.1 mg/kg body mass to about 1.0 mg/kg of body mass, administered via intra-muscular injection. In a particular exemplary embodiment, the method includes administering a dose of 0.2 mg/kg body mass via intra-muscular injection. The method may include administering a first dose before weaning, and administering a second dose after weaning. Further, the first dose may be administered a day before commencing weaning, and the second dose 3 days after weaning has commenced.

    摘要翻译： 提供了一种用皮质醇激动剂处理断奶仔猪的方法，其中所述方法包括以治疗有效量向断奶仔猪施用一剂皮质醇激动剂，以引起与类似的断奶相比的体重增加， 未经处理的仔猪 皮质醇激动剂可以是地塞米松。 此外，通过肌内注射给药，剂量可以为约0.1mg / kg体重至约1.0mg / kg体重。 在一个具体的示例性实施方案中，该方法包括通过肌内注射施用0.2mg / kg体重的剂量。 该方法可以包括在断奶前施用第一剂量，以及在断奶后施用第二剂量。 此外，第一剂可以在开始断奶前一天施用，并且断奶3天后的第二剂量开始。

    TREATMENT OF ATOPIC DERMATITIS IN NON-HUMAN ANIMALS
    3.
    发明申请
    TREATMENT OF ATOPIC DERMATITIS IN NON-HUMAN ANIMALS 审中-公开
    治疗非人类动物中的病原体

    公开(公告)号：WO2015042596A1

    公开(公告)日：2015-03-26

    申请号：PCT/US2014/057031

    申请日：2014-09-23

    申请人： KINDRED BIOSCIENCES, INC

    发明人： CHIN, Richard ,  REYES, Noe

    IPC分类号： A61K31/445

    CPC分类号： A61K31/445 ,  A23K20/10 ,  A23K20/111 ,  A23K20/132 ,  A23K20/168 ,  A23K50/40 ,  A61K9/0056 ,  A61K9/2018 ,  A61K9/2054 ,  A61K45/06 ,  A61K2300/00

    摘要： Atopic dermatitis and pruritus can be efficaciously treated in non-human animals by administering fexofenadine. In a first aspect, the present invention provides a method for treating AD or pruritus, said method comprising orally administering to a non-human patient in need of treatment a therapeutically effective dose of fexofenadine at a dose of at least 20 mg/kg by weight per day. In some instances the present invention provides a method for treating AD in a canine or feline, said method comprising orally administering a therapeutically effective dose of fexofenadine at a dose of at least 20 mg/kg by weight per day. In many embodiments, treatment will continue on a consecutive daily basis for many weeks, if not for the rest of the animal's life.

    摘要翻译： 特应性皮炎和瘙痒可以通过施用非索非那定在非人类动物中有效治疗。 在第一方面，本发明提供了一种治疗AD或瘙痒症的方法，所述方法包括口服给予需要治疗的非人类患者治疗有效剂量的非索非那定，剂量为至少20mg / kg 每天。 在一些情况下，本发明提供了在犬或猫科动物中治疗AD的方法，所述方法包括以每天至少20mg / kg的剂量口服施用治疗有效剂量的非索非那定。 在许多实施方案中，治疗将在连续的每天持续数周，如果不是在动物的其余部分的生命中。

    ANIMAL FEED INCLUDING CATIONIC CHOLESTEROL ADDITIVE
    4.
    发明申请
    ANIMAL FEED INCLUDING CATIONIC CHOLESTEROL ADDITIVE 审中-公开
    动物饲料包括阳离子胆固醇添加剂

    公开(公告)号：WO2014193562A1

    公开(公告)日：2014-12-04

    申请号：PCT/US2014/034986

    申请日：2014-04-22

    申请人： BRIGHAM YOUNG UNIVERSITY ,  BEUS, Chad S. ,  SAVAGE, Paul B.

    发明人： BEUS, Chad S. ,  SAVAGE, Paul B.

    IPC分类号： A23K1/00 ,  A23K1/18 ,  A23K1/165

    CPC分类号： A61K31/575 ,  A23K20/10 ,  A23K20/168 ,  A23K50/10 ,  A23K50/20 ,  A23K50/30 ,  A23K50/45 ,  A23K50/75 ,  A23V2002/00 ,  A23V2200/32

    摘要： Methods and feed compositions for increasing health of agricultural animals incude administering a cationic cholesterol additive through the diet of the animal, such as through solid feed or drinking water of the animals. The method includes feeding an animal a diet comprised of a cationic cholesterol additive, such as a compound with a sterol backbone and a plurality of cationic groups attached thereto. The feed composition may include a solid or liquid feed component and a cationic cholesterol additive. The methods and compositions are useful for animals raised in confined feed operations, such as cattle, swine, horses, sheep, or poultry, and can reduce harmful bacteria in the digestive tract, increase beneficial bacteria flora, improve feed conversion efficiency, reduce morbity and/or mortality, and/or yield harvested meat having reduced content of harmful bacteria.

    摘要翻译： 用于增加农业动物健康的方法和饲料组合物通过动物的饮食，例如通过动物的固体饲料或饮用水来施用阳离子胆固醇添加剂。 该方法包括向动物喂食由阳离子胆固醇添加剂（例如化合物与固醇骨架）和多个连接到其上的阳离子基团组成的饮食。 饲料组合物可以包括固体或液体进料组分和阳离子胆固醇添加剂。 这些方法和组合物可用于在限制饲料操作中饲养的动物，例如牛，猪，马，羊或家禽，并且可以减少消化道中的有害细菌，增加有益的细菌菌群，提高饲料转化效率，降低发病率 /或死亡率，和/或产生具有降低的有害细菌含量的收获肉。

    COMPOSITIONS AND METHODS FOR INHIBITING REPRODUCTION IN TADPOLE SHRIMP
    6.
    发明申请
    COMPOSITIONS AND METHODS FOR INHIBITING REPRODUCTION IN TADPOLE SHRIMP 审中-公开
    用于抑制TADPOLE SHRIMP中复制的组合物和方法

    公开(公告)号：WO2010059594A1

    公开(公告)日：2010-05-27

    申请号：PCT/US2009/064718

    申请日：2009-11-17

    申请人： CALIFORNIA STATE UNIVERSITY, FRESNO FOUNDATION ,  TSUKIMURA, Dr. Brian K C

    发明人： TSUKIMURA, Dr. Brian K C

    IPC分类号： A01N25/12

    CPC分类号： A61K47/46 ,  A01N49/00 ,  A23K20/168 ,  A23K20/184 ,  A23K40/25 ,  A23K50/80 ,  A61K31/22 ,  A61K31/232 ,  A61K45/06 ,  Y02A40/818 ,  A01N25/28 ,  A01N59/00 ,  A01N59/06 ,  A01N59/08 ,  A01N59/20 ,  A01N63/02 ,  A01N2300/00 ,  A61K2300/00

    摘要： Compositions and methods for reducing tadpole shrimp populations in temporary pools using the hormone methyl famesoate Compositions can include a dry base having a bulk ingredient, a viscous additive having an oily compound, a saline solution, and preparation having an effective amount of phospholipid-encapsulated methyl famesoate The composition can be formed by combining the dry base and the viscous additive into a first mixture and adding all or a portion of the saline solution to form a crumbly consistency Then, the methyl famesoate preparation can be added The composition may then be formed into a plurality of particles having shapes and sizes for consumption by the tadpole shrimp In use, the particles may be dispensed prior to, or immediately after, the temporary pools are flooded with water The particles may be formed such that they can withstand exposure to water for between about 4 to about 14 days

    摘要翻译： 使用激素甲基烟酸酯减少临时池中的ad ole对虾种群的组合物和方法组合物可以包括具有主体成分的干燥基质，具有油性化合物的粘性添加剂，盐水溶液和具有有效量的磷脂包封的甲基 fameoate组合物可以通过将干燥基料和粘性添加剂混合到第一混合物中并加入全部或一部分盐水溶液形成脆性稠合物形成。然后，可以加入甲磺酸甲酯制剂然后将组合物形成 多种具有t ole虾消耗形状和尺寸的颗粒在使用中，可以在临时池被淹水之前或之后立即分配颗粒。颗粒可以形成为使得它们可以经受暴露于水以供 约4至14天之间

    METHOD FOR LENGTHENING THE SEASONAL MOBILITY PERIOD OF FISH
    8.
    发明申请
    METHOD FOR LENGTHENING THE SEASONAL MOBILITY PERIOD OF FISH 审中-公开
    增加鱼类的季节性移动时期的方法

    公开(公告)号：WO2006125699A1

    公开(公告)日：2006-11-30

    申请号：PCT/EP2006/061658

    申请日：2006-04-19

    申请人： DESOL BV ,  ELSHOUT, VAN DEN, Wilhelmus Hubertus Henricus Antonius ,  FORIER, Rudi Ludovicus Florent

    发明人： ELSHOUT, VAN DEN, Wilhelmus Hubertus Henricus Antonius ,  FORIER, Rudi Ludovicus Florent

    IPC分类号： A61P3/02 ,  A23K1/18 ,  A23K1/165 ,  A23K1/16

    CPC分类号： A23K50/80 ,  A23K20/163 ,  A23K20/168 ,  A23K20/184 ,  A23K40/00

    摘要： This invention is in the field of animal feed, more in particular in the field of fish feed. Surprisingly, it has been found that the seasonal mobility period of fish may be lengthened by interfering with the diet of the fish. We found that it is possible to increase the seasonal mobility period of fish to such an extent that it is even active at temperatures as low as 2 degrees Celsius. Such may be accomplished by adding naturally occurring substances to the feed of the fish. Examples of these naturally occurring substances are immune enhancing ingredients like beta-glucans and/or small amounts of phytohormones like auxin or gibberellic acid. Also, combinations of these substances, in particular the combination of beta-glucans and phytohormones, were shown to have a synergistic effect in that they lengthened the seasonal mobility period of the fish more than the individual components on their own.

    摘要翻译： 本发明属于动物饲料领域，特别是在饲料领域。 令人惊讶的是，已经发现，通过干扰鱼的饮食，可以延长鱼的季节性流动期。 我们发现有可能增加鱼类的季节性流动性，使其在低至2摄氏度的温度下甚至活跃。 这可以通过向鱼的饲料中加入天然存在的物质来实现。 这些天然存在的物质的实例是免疫增强成分如β-葡聚糖和/或少量植物激素如生长素或赤霉酸。 此外，这些物质的组合，特别是β-葡聚糖和植物激素的组合显示出具有协同效应，因为它们自身延长了鱼的季节性迁移期，而不是单独的成分。