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    CONCURRENT TRANSMITTING AND RECEIVING ELECTROENCEPHALOGRAPH ELECTRODES
    3.
    发明申请
    CONCURRENT TRANSMITTING AND RECEIVING ELECTROENCEPHALOGRAPH ELECTRODES 审中-公开
    并发传输和接收电子记录电极

    公开(公告)号：WO2018071915A1

    公开(公告)日：2018-04-19

    申请号：PCT/US2017/056820

    申请日：2017-10-16

    Applicant: SANTA FE NEUROSCIENCES, LLC ,  WEISEND, Michael, P.

    Inventor： WEISEND, Michael, P.

    IPC: A61N1/04 ,  A61B5/0478 ,  A61B5/0476

    CPC classification number: A61N1/0456 ,  A61B5/04012 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/4836 ,  A61B5/6803 ,  A61B5/6814 ,  A61B5/7203 ,  A61B2562/0215 ,  A61B2562/046 ,  A61N1/04 ,  A61N1/0529 ,  A61N1/36031

    Abstract: Disclosed herein is a brain stimulation apparatus. The brain stimulation apparatus can comprise an electrode disposed on a scalp of a subject and configured to simultaneously stimulate and record from a same site of the scalp. The electrode can comprise a comb shape comprising a plurality of tube-like prongs, each of the plurality of prongs extending down to touch the scalp. The brain stimulation apparatus can comprise a first input to the electrode connecting a first subset of the plurality of prongs to a stimulator for driving a transcranial electrical stimulation (TES), and a second input to the electrode connecting to a second subset of the plurality of prongs to an Electroencephalograph (EEG) recorder. The first input and the second input can be disposed interleaved to enable direct noise cancellation.

    Abstract translation: 这里公开了一种脑刺激设备。 脑刺激设备可以包括布置在受试者的头皮上并被配置为同时刺激和记录来自头皮的相同部位的电极。 电极可以包括梳形，其包括多个管状尖头，多个尖头中的每一个向下延伸以接触头皮。 脑刺激设备可以包括到电极的第一输入，其连接多个叉的第一子集到用于驱动经颅电刺激（TES）的刺激器，并且第二输入到电极连接到多个 插入脑电图（EEG）记录器。 第一个输入和第二个输入可以交错排列，以实现直接的噪音消除。

    IMPLANTABLE MODULAR ELECTRODE ARRAY ASSEMBLY
    4.
    发明申请
    IMPLANTABLE MODULAR ELECTRODE ARRAY ASSEMBLY 审中-公开
    可植入模块化电极阵列组件

    公开(公告)号：WO2017062577A2

    公开(公告)日：2017-04-13

    申请号：PCT/US2016/055687

    申请日：2016-10-06

    Applicant: MEDTRONIC, INC.

    Inventor： OLSON, Robert L.

    IPC: A61N1/05 ,  A61N1/375 ,  H01R24/60

    CPC classification number: A61N1/0529 ,  A61B5/0478 ,  A61N1/0531 ,  A61N1/0551 ,  A61N1/372 ,  A61N1/375 ,  H01R12/79 ,  H01R24/60 ,  H01R31/005 ,  H01R2201/12

    Abstract: This disclosure describes various modular electrode assemblies. For example, an implantable modular electrode assembly may include a hub including a plurality of electrical contacts configured to receive electrical signals from an implantable medical device, a first electrode module including a first substrate and a first plurality of electrodes on the first substrate, and a second electrode module including a second substrate and a second plurality of electrodes on the second substrate. The first and second electrode modules may be connectable to the hub, where the plurality of electrical contacts electrically communicate with the first and second plurality of electrodes.

    Abstract translation: 本公开描述了各种模块化电极组件。 例如，可植入模块化电极组件可以包括毂，其包括多个电触点，其被配置为从可植入医疗装置接收电信号，第一电极模块包括第一衬底和第一衬底上的第一多个电极，以及 所述第二电极模块包括第二基板和所述第二基板上的第二多个电极。 第一和第二电极模块可以连接到轮毂，其中多个电触头与第一和第二多个电极电连通。

    IMPROVED METHODS AND APPARATUS FOR CORTICAL STIMULATION MAPPING DURING SURGICAL PROCEDURES
    5.
    发明申请
    IMPROVED METHODS AND APPARATUS FOR CORTICAL STIMULATION MAPPING DURING SURGICAL PROCEDURES 审中-公开
    外科手术期间用于矫正刺激性图像的改进方法和装置

    公开(公告)号：WO2017060755A1

    公开(公告)日：2017-04-13

    申请号：PCT/IB2015/057668

    申请日：2015-10-07

    Applicant: SYNAPTIVE MEDICAL (BARBADOS) INC.

    Inventor： WOOD, Michael Frank Gunter ,  JAGGA, Arun Victor ,  YUWARAJ, Murugathas

    IPC: A61N1/05

    CPC classification number: A61B5/0476 ,  A61B5/04001 ,  A61B5/0478 ,  A61B5/04845 ,  A61B5/064 ,  A61B5/6865 ,  A61B5/6868 ,  A61B17/3421 ,  A61B17/3423 ,  A61B34/25 ,  A61B2034/2055 ,  A61B2562/04 ,  A61N1/0529 ,  A61N1/0539 ,  A61N1/36017

    Abstract: An apparatus and method is provided for intraoperative tissue stimulation during port-based surgery. The apparatus includes an access port and electrical terminals attached to the access port for tissue stimulation. In an alternative embodiment, the apparatus may include an access port, with or without electrical terminals attached to the access port for tissue stimulation, and electrocorticography sensors attached to the access port. The method includes inserting an access port into a tissue, applying an electrical potential to the tissue using electrical terminals attached to the access port, and measuring consequent neural activity using electrocorticography sensors attached to the access port.

    Abstract translation: 在基于口腔的手术期间提供了用于术中组织刺激的装置和方法。 该装置包括接入端口和附接到接入端口的用于组织刺激的电气端子。 在替代实施例中，该装置可以包括接入端口，其具有或不具有附接到用于组织刺激的接入端口的电气终端，以及附着到接入端口的电离传感器传感器。 该方法包括将访问端口插入到组织中，使用附接到访问端口的电气终端向组织施加电势，以及使用附接到访问端口的电皮质传感器来测量随后的神经活动。

    FLEXIBLE COMPLEMENTARY METAL-OXIDE-SEMICONDUCTOR PROBES FOR CHRONIC, LARGE-SCALE NEURAL STIMULATION AND RECORDING
    6.
    发明申请
    FLEXIBLE COMPLEMENTARY METAL-OXIDE-SEMICONDUCTOR PROBES FOR CHRONIC, LARGE-SCALE NEURAL STIMULATION AND RECORDING 审中-公开
    用于慢性，大规模神经刺激和记录的柔性补充金属氧化物半导体探针

    公开(公告)号：WO2017035530A1

    公开(公告)日：2017-03-02

    申请号：PCT/US2016/049278

    申请日：2016-08-29

    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

    Inventor： SHEPARD, Kenneth ,  TSAI, David ,  KANG, Hongki ,  THIMOT, Jordan

    IPC: A61B5/04 ,  A61N1/00

    CPC classification number: A61N1/37223 ,  A61B5/0031 ,  A61B5/0478 ,  A61B5/7225 ,  A61B2560/0219 ,  A61N1/00 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/3787 ,  H04B5/0081

    Abstract: Systems and methods for providing neural stimulation and recording on a subject using flexible complementary CMOS probes are provided. Disclosed systems can include a flexible probe adapted for insertion into a portion of a brain of the subject, the flexible probe comprising a tail portion and a head portion. The tail portion can include a plurality of electrodes configured to be coupled to the brain and a plurality of front-end amplifiers. Each of the plurality of front-end amplifiers can be configured to amplify a signal received from a corresponding electrode of the plurality of electrodes. The head portion can include one or more inductors configured to enable two-way communication with a wireless reader through a near-field inductive link.

    Abstract translation: 提供了使用灵活的互补CMOS探针在受试者身上提供神经刺激和记录的系统和方法。 公开的系统可以包括适于插入到受试者的脑的一部分中的柔性探针，所述柔性探针包括尾部和头部。 尾部可以包括被配置为耦合到大脑的多个电极和多个前端放大器。 多个前端放大器中的每一个可被配置为放大从多个电极的对应电极接收的信号。 磁头部分可以包括一个或多个电感器，其被配置为通过近场感应链路实现与无线读取器的双向通信。

    SYSTEMS AND METHODS FOR MAKING AND USING IMPROVED CONTACT ARRAYS FOR ELECTRICAL STIMULATION SYSTEMS
    7.
    发明申请
    SYSTEMS AND METHODS FOR MAKING AND USING IMPROVED CONTACT ARRAYS FOR ELECTRICAL STIMULATION SYSTEMS 审中-公开
    制造和使用改进的电刺激系统接触阵列的系统和方法

    公开(公告)号：WO2016164361A1

    公开(公告)日：2016-10-13

    申请号：PCT/US2016/026044

    申请日：2016-04-05

    Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATION

    Inventor： GOVEA, Michael, X. ,  HOWARD, Joshua, Dale

    IPC: A61N1/375 ,  A61N1/05 ,  H01R13/52 ,  H01R13/629 ,  H01R13/64 ,  H01R43/26 ,  H01R24/58

    CPC classification number: A61N1/05 ,  A61N1/0529 ,  A61N1/0551 ,  A61N1/36 ,  A61N1/3752

    Abstract: An electrical stimulation lead or lead extension includes a body having an outer surface, a proximal end, a proximal portion, at least one distal portion, an outer surface, a perimeter, and a longitudinal length, the body defining an alignment slit extending distally from the proximal end of the body and splitting the proximal portion of the body into two transversely space-apart sections; first contacts disposed along the distal portion of the body; segmented second contacts disposed along the proximal portion of the body, where each segmented second contact extends around less than the entire perimeter of the body and is separated from all other segmented second contacts by portions of the body or the alignment slit; and conductors electrically coupling the first contacts to the second contacts.

    Abstract translation: 电刺激引线或引线延伸部包括具有外表面，近端，近端部分，至少一个远端部分，外表面，周边和纵向长度的主体，所述主体限定向远侧延伸的对准狭缝 身体的近端并将身体的近端部分分成两个横向间隔开的部分; 沿着身体的远端部分设置的第一触点; 分段的第二触点沿着主体的近端部分设置，其中每个分段的第二触点围绕小于整个本体的周边延伸，并且通过主体或对准狭缝的一部分与所有其它分段的第二触点分离; 以及将第一触点电耦合到第二触点的导体。

    SYSTEMS AND METHODS FOR SELECTIVE MEMORY ENHANCEMENT AND/OR DISRUPTION
    8.
    发明申请
    SYSTEMS AND METHODS FOR SELECTIVE MEMORY ENHANCEMENT AND/OR DISRUPTION 审中-公开
    选择性内存增强和/或破坏的系统和方法

    公开(公告)号：WO2016134271A1

    公开(公告)日：2016-08-25

    申请号：PCT/US2016/018700

    申请日：2016-02-19

    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY

    Inventor： MILLER, Earl K. ,  BRINCAT, Scott L.

    IPC: A61N1/36

    CPC classification number: A61N1/36082 ,  A61N1/0456 ,  A61N1/0529 ,  A61N1/36025 ,  A61N1/36146 ,  A61N1/36196 ,  A61N1/37247

    Abstract: Systems and methods are disclosed for selectively reinforcing or weakening memory associations. At least one current generator provides an electrical current including a plurality of oscillating pulses with at least one predetermined frequency. A user interface includes at least one output device for delivering a sensory stimulus to a user and at least one user input device for registering a response to the stimulus. At least one processor determines from the response, based on at least one predetermined standard, whether an underlying memory association is desired or undesired and respectively sets the at least one predetermined frequency to be a beta or theta frequency. Consequently, the electrical current is generated and administered, via at least one electrode pair, thereby stimulating at least one specific portion of the user's brain so as to reinforce or weaken the underlying memory association.

    Abstract translation: 公开了用于选择性地增强或削弱记忆关联的系统和方法。 至少一个电流发生器提供包括具有至少一个预定频率的多个振荡脉冲的电流。 用户界面包括用于将感觉刺激传送给用户的至少一个输出设备和用于注册对刺激的响应的至少一个用户输入设备。 至少一个处理器基于至少一个预定标准从响应确定底层存储器关联是期望还是不期望的，并且分别将至少一个预定频率设置为β或θ频率。 因此，通过至少一个电极对产生和施加电流，由此刺激用户脑部的至少一个特定部分，以便加强或削弱下面的记忆关联。

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