UNIVERSAL ORTHOGONAL NETWORK BIOINKS FOR THREE-DIMENSIONAL BIOPRINTING

    公开(公告)号:WO2021041372A1

    公开(公告)日:2021-03-04

    申请号:PCT/US2020/047732

    申请日:2020-08-25

    Abstract: A method of bioprinting a bioink printed structure and a bioprinted composition resulting from this method is provided. Biological cells are mixed with biomaterial inks. These biomaterial inks have a biopolymer backbone with grafted thereto a first bio-orthogonal chemical group. The mixed biological cells and biomaterial inks are extruded into a support bath. The next step is diffusing crosslinking molecules which have a second (complementary to the first) bio-orthogonal chemical group, in the support bath, whereby the diffusing crosslinking molecules react via bioorthogonal click-chemistry between the first and second bio-orthogonal chemical groups resulting in covalently crosslinking the biomaterial ink into a printed structure. Embodiments of this invention can be directed towards personalized medicine and printed tissue engineering constructs, as well as drug discovery by printing complex tissue mimics or printing model vasculature for studying cardiovascular disease.

    BIO-INK COMPOSITIONS, ENVIRONMENTALLY-SENSITIVE OBJECTS, AND METHODS OF MAKING THE SAME

    公开(公告)号:WO2020264036A1

    公开(公告)日:2020-12-30

    申请号:PCT/US2020/039442

    申请日:2020-06-24

    Abstract: Silkworm silk, has been processed into a variety of new material formats including, hydrogels, ultrathin films, thick films, conformal coatings, 3D porous or solid matrices, fibers and many related material formats. Silk is processed in an all water-based, room temperature, neutral pH environment, is mechanically stable, edible, and biocompatible. Given the favorable material properties, the use of silk-based inks have been used in a variety of controlled chemical and biological material fabrication on the micro-and nano- scale. Tuning of the properties of silk -based inks has led to the utilization of more diverse printing techniques and has expanded the scale and function of the printed substrates.

    PRINTABLE HYDROGEL, METHOD FOR GENERATING A PRINTABLE HYDROGEL, LYOPHILIZATE, PRINTED PRODUCT AND 3D PRINTING METHOD

    公开(公告)号:WO2020234167A1

    公开(公告)日:2020-11-26

    申请号:PCT/EP2020/063653

    申请日:2020-05-15

    Applicant: ETH ZÜRICH

    Abstract: The invention relates to a printable hydrogel comprising a plurality of microstrands comprising or consisting of a polymer, wherein the microstrands have a diameter of 1 µm to 500 µm and an aspect ratio of at least 100:1, and wherein said microstrands are entangled with each other. A further aspect of the invention is a lyophilizate comprising a plurality of microstrands comprising or consisting of a polymer, wherein the microstrands have a diameter of 1 µm to 500 µm and an aspect ratio of at least 100:1, and wherein said microstrands are entangled with each other. Furthermore, a method for generating a printable hydrogel comprising the step of providing a cross-linked hydrogel, passing said cross-linked hydrogel through a sieve comprising a plurality of openings, such that a plurality of microstrands having a diameter of 1 µm to 500 µm and an aspect ratio of at least 100:1 are generated, and passing said microstrands through a volume, such that the microstrands are entangled with each other, is provided. The invention further relates to a 3D printed product and a 3D printing method using the hydrogel.

    AN AUTOMATIC DEVICE DETERMINING CHARACTERISTIC COLORS AND PRODUCING MIXTURES
    9.
    发明申请
    AN AUTOMATIC DEVICE DETERMINING CHARACTERISTIC COLORS AND PRODUCING MIXTURES 审中-公开
    一种确定特性颜色和生产混合物的自动装置

    公开(公告)号:WO2012023911A1

    公开(公告)日:2012-02-23

    申请号:PCT/TR2011/000187

    申请日:2011-08-12

    Applicant: DAL, Yilmaz

    Inventor: DAL, Yilmaz

    CPC classification number: G06K9/00154

    Abstract: The present invention is in respect of a device that produces cyphers specific for the persons or establishments and then produces mixtures that are appropriate for the said cyphers and then analyses these mixtures by way of atomic absorption method and then determines to whom or to which company the relevant mixture belongs to. The device determining the characteristic colors and produces mixtures takes the eye retina or the finger print or the tone of voice of the person consist of a sensor that either creates a cypher that is specific for the person or the company or that recognizes the cyphers that have been created by the said persons or companies, a processor that determines the amounts of the mixtures to be obtained from the major colors depending on the cypher that had been produced or the color that had been selected by the relevant person, color chambers that contain seven major colors, a mixer in which the colors are being mixed, an outlet in which the colors that had been created are filled in the tubes, a cash entry inlet for the person to be able to make the payment, a color reader that defines the relevant color in terms of to whom or to which company the relevant color belongs to and a server that has been connected to a processor in which all of the cyphers and all of the information is retained.

    Abstract translation: 本发明涉及一种产生针对人或机构特有的密码的装置,然后产生适合于所述密封件的混合物,然后通过原子吸收法分析这些混合物,然后确定向哪个或哪个公司 相关混合物属于。 确定特征颜色并产生混合物的装置使眼睛视网膜或指纹或人的声音由传感器组成,该传感器可以创建专用于人或公司的密码,或识别具有 由所述个人或公司创建,处理器根据所生产的密封件或由相关人员选择的颜色确定要从主要颜色获得的混合物的量,颜色室包含七个 主要颜色,混合颜色的混合器,其中已经产生的颜色填充在管中的出口,用于能够进行支付的人的现金进入口,定义了颜色的彩色阅读器 与相关颜色属于哪个或哪个公司相关的颜色的相关颜色以及已连接到所有密码和所有信息所保留的处理器的服务器 编辑。

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