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公开(公告)号：WO2022132935A1
公开(公告)日：2022-06-23
申请号：PCT/US2021/063566
申请日：2021-12-15
Applicant: HACH COMPANY
Inventor： RAJASEKHARAN, Vishnu Vardhanan , KROLL, Dan Jonathan
Abstract: A method for digesting at least one analyte of an aqueous sample includes the following steps: introducing an aqueous sample comprising at least one analyte into a digestion device comprising one or more carbon substituted material electrodes; digesting the at least one analyte by applying an electrical potential between an anode and a cathode of the digestion device, wherein the digesting comprises a stepwise disintegration; measuring the at least one analyte of the aqueous sample from the digested material, using a measurement device selected from the group consisting of: an electrochemical device and an optical measurement device; and modifying the electrical potential based upon the measurement of the at least one analyte.
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公开(公告)号：WO2020155501A1
公开(公告)日：2020-08-06
申请号：PCT/CN2019/090139
申请日：2019-06-05
Applicant: 福建青拓特钢技术研究有限公司
Abstract: 一种带自动搅拌装置的测硫仪，包括电解池（1）、基座（2）和磁性搅拌子（5），基座（2）固定设在电解池（1）内部的底面上；基座（2）上以基座（2）的中心为圆心圆周分布设有至少两个支架，支架包括水平设置的横梁（3）和与横梁（3）的一端垂直向上连接的竖梁（4），横梁（3）远离竖梁（4）的一端与基座（2）固定连接，竖梁（4）的表面设有凹槽（41），磁性搅拌子（5）的中部设有凸起（51），凸起（51）插入凹槽（41）内且可转动，电解池（1）的外部设有驱动磁性搅拌子（2）旋转的电机（6）。
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3.发明申请
公开(公告)号：WO2015090257A1
公开(公告)日：2015-06-25
申请号：PCT/CZ2014/000158
申请日：2014-12-17
Applicant: USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. , CESKA ZEMEDELSKA UNIVERZITA V PRAZE , USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, V.V.I.
Inventor： JAKLOVA DYTRTOVA, Jana , CVACKA, Josef , JAKL, Michal , NAVRATIL, Tomas
IPC: G01N27/403 , G01N27/44 , H01J49/16 , G01N30/72 , G01N30/06
CPC classification number: G01N30/7266 , G01N27/403 , G01N27/44 , G01N2030/067
Abstract: A method for detection and determination of organic compounds by means of electrochemical activation in an electrochemical cell is described. The flow electrochemical cell provides an alternative to separation methods, upstream mass spectroscopy for the identification and study of particular organic substances. The electrochemically generated ions substances entering the electrochemical cell formed by their oxidation or reduction or electrochemically generated ions from the electrode material and forming adducts with substances contained in the sample matrix are then qualitatively or quantitatively analyzed with a mass spectrometer. The electrochemical activation can be used even for substances that are in the mass spectrometer otherwise undetectable. Thanks to the interchangeable system of the working electrodes the device is applicable in laboratories for serial analysis. Alternatively this cell can be used for specific purposes of basic research, where the easy handling and the possibility of alternative exchange working electrodes (possible to select different electrode e.g. Cu, Ag and Au) allows further modification of the electrochemical system.˙
Abstract translation: 描述了通过电化学电池中的电化学活化来检测和测定有机化合物的方法。 流动电化学电池提供了分离方法的替代方法，用于鉴定和研究特定有机物质的上游质谱法。 然后用质谱仪定性或定量分析进入电化学电池的电化学生成的离子物质，其通过其氧化或还原或电化学产生的离子从电极材料形成，并与样品基质中包含的物质形成加合物。 电化学活化可以用于质谱仪中甚至不能检测到的物质。 由于工作电极的可互换系统，该器件适用于实验室进行串行分析。 或者，该电池可以用于基础研究的特定目的，其中易于处理和替代交换工作电极（可能选择不同电极，例如Cu，Ag和Au）的可能性允许进一步修改电化学系统。
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公开(公告)号：WO2012056247A1
公开(公告)日：2012-05-03
申请号：PCT/GB2011/052105
申请日：2011-10-28
Applicant: DNA ELECTRONICS LTD , TOUMAZOU, Christofer , LIU, Yan , GEORGIOU, Pantelis , OU, Chung Pei , REED, Sam
Inventor： TOUMAZOU, Christofer , LIU, Yan , GEORGIOU, Pantelis , OU, Chung Pei , REED, Sam
IPC: G01N27/44 , G01N27/414 , C12Q1/68
CPC classification number: C12Q1/6874 , C12Q1/6825 , C12Q1/6858 , G01N27/4145 , G01N27/44 , C12Q2533/101 , C12Q2565/301 , C12Q2565/607 , C12Q2565/501
Abstract: An apparatus comprises a transducer having a first output signal and arranged to receive an electrical input. The transducer switches the first output signal between an ON and OFF state. The apparatus comprises a chemical sensing surface coupled to the transducer arranged to receive a chemical input.A signal generator oscillates one or more of said inputs to vary the switching point of the transducer. The oscillating input may be the chemical input and/or the electrical input. The output signal may be a pulse whose period ON or OFF is determined by the oscillating input modulated by the chemical input.
Abstract translation: 一种装置包括具有第一输出信号并被布置成接收电输入的换能器。 传感器在ON和OFF状态之间切换第一个输出信号。 该装置包括耦合到换能器的化学感测表面，布置成接收化学输入。信号发生器振荡一个或多个所述输入以改变换能器的切换点。 振荡输入可以是化学输入和/或电输入。 输出信号可以是其周期ON或OFF由通过化学输入调制的振荡输入确定的脉冲。
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公开(公告)号：WO0206788A3
公开(公告)日：2002-08-29
申请号：PCT/US0121314
申请日：2001-07-06
Applicant: USF FILTRATION & SEPARATIONS , HODGES ALASTAIR , CHATELIER RON
Inventor： HODGES ALASTAIR , CHATELIER RON
IPC: G01N33/483 , C12Q1/00 , G01N27/28 , G01N27/30 , G01N27/327 , G01N27/416 , G01N27/42 , G01N27/44 , G01N33/487 , G01N33/49 , G01N33/543 , G01N33/66 , G01N33/72 , G01N33/84 , G01N27/403 , G01N27/413 , G01N27/49
Abstract: The present invention relates to the measurement of the progress of a chemical reaction that generates an electroactive reaction product that is subsequently detected at an electrode amperometrically or coulometrically. The method is useful in applications where it is desirable to follow the progress of a chemical reaction, particularly in sensor applications where the progress of the reaction of an analyte can be useful in determining the analyte concentration. Sensors used in such applications may include a working electrode (2) and a counter electrode (3) disposed on an electrically insulating substrate (1), and may also include a second substrate (5) upon which is disposed a layer of chemical reactants (4).
Abstract translation: 本发明涉及产生电活性反应产物的化学反应的进展的测量，随后在电极电位或电量法检测电极。 该方法在希望遵循化学反应进程的应用中是有用的，特别是在分析物的反应进程可用于测定分析物浓度的传感器应用中。 在这种应用中使用的传感器可以包括设置在电绝缘基板（1）上的工作电极（2）和对电极（3），并且还可以包括第二基板（5），在其上设置一层化学反应物 4）。
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Patent Agency Ranking
公开(公告)号：WO02040991A2
公开(公告)日：2002-05-23
申请号：PCT/US2001/027790
申请日：2001-11-01
CPC classification number: G01N31/168
Abstract: The invention relates to a formed tablet calibration standard-reagent for calibrating Karl Fischer reactions for determining water content in a substance, said reagent containing a first component, namely sodium tartrate dihydrate, and a second component, namely magnesium stearate. The invention further relates to a method for determining the water content of a substance using a Karl Fischer analysis. The invention further relates to a formed tablet calibration standard-reagent kit, comprising a sealed package containing said formed tablet calibration standard-reagent.
Abstract translation: 本发明涉及用于校准卡尔费休反应的成型片剂校准标准试剂，用于测定物质中的含水量，所述试剂含有第一组分即酒石酸二钠水合物，第二组分即硬脂酸镁。 本发明还涉及使用卡尔费休分析法确定物质的含水量的方法。 本发明还涉及形成的片剂校准标准试剂盒，其包含含有所述形成的片剂校准标准试剂的密封包装。
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7.发明申请METHODS, SYSTEMS, AND ASSOCIATED IMPLANTABLE DEVICES FOR DYNAMIC MONITORING OF TUMORS 审中-公开用于动态动态监测肿瘤的方法，系统和相关的可植入装置
公开(公告)号：WO00018294A1
公开(公告)日：2000-04-06
申请号：PCT/US1999/022638
申请日：1999-09-29
CPC classification number: A61B5/1473 , A61B5/0031 , A61B5/14539 , A61B5/14865 , A61B5/1495 , A61B5/417 , A61B2562/028 , A61B2562/085 , A61N5/1048 , A61N5/1071 , G06F19/00 , G06F19/3481
Abstract: Methods of monitoring and evaluating the status of a tumor undergoing treatment includes monitoring in vivo at least one physiological parameter associated with a tumor in a subject undergoing treatment, transmitting data from an in situ located sensor to a receiver external of the subject, analyzing the transmitted data, repeating the monitoring and transmitting steps at sequential points in time and evaluating a treatment strategy. The method provides dynamic tracking of the monitored parameters over time. The method can also include identifying in a substantially real time manner when conditions are favorable for treatment and when conditions are unfavorable for treatment and can verify or quantify how much of a known drug dose or radiation dose was actually received at the tumor. The method can include remote transmission from a non-clinical site to allow oversight of the tumor's condition even during non-active treatment periods (in between active treatments). The disclosure also includes monitoring systems with in situ in vivo biocompatible sensors and telemetry based operations and related computer program products.
Abstract translation: 监测和评估正在进行治疗的肿瘤状态的方法包括在体内监测经受治疗的受试者中与肿瘤相关的至少一个生理参数，将数据从原位定位的传感器传输到对象外部的接受体，分析所传送的 数据，在连续的时间点重复监测和传送步骤，并评估治疗策略。 该方法提供了随时间监视的参数的动态跟踪。 该方法还可以包括当条件有利于治疗时以及当条件不利于治疗时以基本上实时的方式进行鉴定，并且可以验证或量化在肿瘤中实际接收了多少已知药物剂量或辐射剂量。 该方法可以包括从非临床部位的远程传输，以允许即使在非活动治疗期间（在主动治疗之间）也可以监视肿瘤的状况。 本公开还包括具有原位体内生物相容性传感器和基于遥测的操作和相关计算机程序产品的监测系统。
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公开(公告)号：WO99024369A2
公开(公告)日：1999-05-20
申请号：PCT/US1998/023781
申请日：1998-11-06
IPC: C02F1/00 , C02F1/42 , C02F1/461 , C02F1/467 , C02F1/72 , C02F1/76 , G01N27/44 , G01N27/49 , C02F1/46
CPC classification number: G01N27/4045 , C02F1/008 , C02F1/42 , C02F1/46104 , C02F1/4674 , C02F1/72 , C02F1/766 , C02F2001/46119 , C02F2001/46123 , C02F2001/46128 , C02F2103/023 , C02F2103/42 , C02F2201/4611 , C02F2201/4612 , C02F2201/46125 , C02F2201/4617 , C02F2209/006 , C02F2209/06 , C02F2303/04 , G01N27/44 , Y02W10/37
Abstract: An automatic sanitizing system (12) accurately maintains a desired concentration of a sanitizing agent within a water feature (7) filled with water. The automatic sanitizing system (12) includes a sanitizing agent generator (20), an amperometric sensor and a control system (1). The sanitizing agent generator (20) communicates with the water feature (7). The amperometric sensor includes a probe (6) positioned in contact with water and generates an output signal indicative of the concentration of sanitizing agent in the water. The control system (1) receives the signal from the sensor (6) and operates the generator (20) at least between an active state and an inactive state depending on the concentration of the sanitizing agent in the water. The concentration of the sanitizing agent in the water is automatically maintained within a preset range.
Abstract translation: 自动消毒系统（12）能够在充满水的结构（7）中精确地保持消毒剂的期望含量并且包括消毒剂产生器（20）。 安培传感器和控制系统（1）。 发生器（20）与结构（7）连通。 安培传感器包括放置成与水接触并且产生指示清洁剂的水含量的输出信号的探针（6）。 取决于消毒剂的水含量，控制系统（1）接收来自传感器（6）的信号并至少在活动状态和非活动状态之间控制发生器（20）。 该内容自动保持在预先设定的内容范围内。
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公开(公告)号：WO1996001422A1
公开(公告)日：1996-01-18
申请号：PCT/GB1995001425
申请日：1995-06-19
Applicant: UNILEVER PLC , UNILEVER N.V.
Inventor： UNILEVER PLC , UNILEVER N.V. , BIRCH, Brian, Jeffrey , MORRIS, Nicholas, Andrew
IPC: G01N27/44
CPC classification number: G01N27/44
Abstract: A titration electrode device for measuring the amount of a species in solution in a test liquid comprises a counter electrode and a generator electrode both in a chamber for receiving a thin layer of test liquid, the two electrodes being located in respective compartments within the chamber such that ionic conduction between the compartments is permitted but diffusion of electrogenerated reagents between the compartments is restricted, the device including reference and sensor electrodes in the chamber.
Abstract translation: 用于测量测试溶液中物质的量的滴定电极装置包括在用于接收薄层测试液体的室中的对电极和发生器电极，所述两个电极位于室内相应的隔室中， 隔间之间的离子传导是允许的，但电隔层间的电生成试剂的扩散受到限制，该装置包括室中的参考电极和传感器电极。
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公开(公告)号：WO2022212650A1
公开(公告)日：2022-10-06
申请号：PCT/US2022/022753
申请日：2022-03-31
Applicant: HACH COMPANY
Inventor： RAJASEKHARAN, Vishnu, Vardhanan , JACKSON, Cary, Burton
IPC: G01N31/00 , G01N33/18 , G01N27/27 , G01N27/302 , G01N27/308 , G01N27/44 , G01N31/005 , G01N31/22 , G01N33/182 , G01N33/1846
Abstract: Method and apparatus for deriving an alkalinity measurement, including: introducing a fluid sample; measuring, a phosphate amount of the fluid sample using a colorimetric reagent; measuring a pH of the fluid sample, wherein the pH of the fluid sample correlates to a hydroxide amount of the fluid sample; introducing an acid to convert all the inorganic carbon to carbon dioxide; applying a positive potential to the SP3 substituted carbon electrode; introducing, prior to or substantially simultaneously during the application of the positive potential to the SP3 substituted carbon electrode and in the reaction chamber, at least one acid reagent comprising a metallic catalyst that converts the carbonate and the partially oxidized species to carbon dioxide; determining total organic carbon by detecting an amount of carbon dioxide produced by the oxidation; determining the total organic carbon from the oxidation of the organic carbon species, and determining a derived alkalinity based upon the phosphate amount, the hydroxide amount, and the amount of carbon dioxide generated from the inorganic carbon.
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