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公开(公告)号：WO2023082073A1
公开(公告)日：2023-05-19
申请号：PCT/CN2021/129680
申请日：2021-11-10
Applicant: 中国科学院精密测量科学与技术创新研究院
Abstract: 一种低成本模块化液氮低温多核磁共振探头，包括杜瓦（1），还包括可插拔线圈（2）和前端增益放大器（3），杜瓦（1）包括筒状夹层腔，筒状夹层腔的中心构成室温腔（5），筒状夹层腔的夹层内通过液氮容器壁（4）分隔为真空腔和液氮腔，真空腔位于室温腔（5）和液氮腔之间，可插拔线圈（2）和前端增益放大器（3）设置在真空腔中，可插拔线圈（2）包括线圈部和可插拔底座，线圈部与可插拔底座之间可插拔连接，可插拔线圈（2）和前端增益放大器（3）连接。可以实现射频脉冲的发射和磁共振信号的接收，适用于小动物全身成像；能实现低设计成本和低运行成本；能有效地提高磁共振信号的信噪比。
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公开(公告)号：WO2023059635A1
公开(公告)日：2023-04-13
申请号：PCT/US2022/045670
申请日：2022-10-04
Applicant: RESONANCE RESEARCH, INC.
Inventor： HETHERINGTON, Hoby P. , STAREWICZ, Piotr M.
IPC: G01R33/20 , G01R33/24 , G01R33/28 , G01R33/38 , G01R33/3873 , G01R33/3875
Abstract: A system and method for shimming an MRI system includes a plurality of shim coils distributed around a bore of the MRI system, the shim coils distributed around the bore so that applying an amount of current associated with each coil of the plurality of coils produces a desired magnetic field, wherein the magnetic field is expressed as a set of spherical harmonic terms, each spherical harmonic term having an order. The amount of current associated with at least one coil is different from the amount of current associated with another coil, and at least one coil of the plurality of coils is configured to contribute to a plurality of spherical harmonic terms having different orders.
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公开(公告)号：WO2023021284A1
公开(公告)日：2023-02-23
申请号：PCT/GB2022/052130
申请日：2022-08-16
Applicant: CAMBRIDGE ENTERPRISE LIMITED
Inventor： COMMENT, Arnaud , GAUNT, Adam
Abstract: In a method for preparing a hyperpolarised sample, for example for carrying out a magnetic resonance technique, the sample is formed as a frozen layer (4) of a starting solution on a surface of a thermoconductive sample holder (1,2). The solution comprises molecules for hyperpolarisation, and photo-reactive molecules. Free radicals are induced in the frozen layer by exposing it to radiation. The sample is then hyperpolarised by dynamic nuclear polarization at a dynamic nuclear polarization temperature. After hyperpolarisation, the temperature of the sample is raised to a thermalisation or quenching temperature by thermal conduction of heat through the sample holder, to quench the free radicals. The polarised sample may then be stored for use, retaining its polarisation.
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4.发明申请
公开(公告)号：WO2023020877A1
公开(公告)日：2023-02-23
申请号：PCT/EP2022/072248
申请日：2022-08-08
Applicant: BUNDESREPUBLIK DEUTSCHLAND, VERTRETEN DURCH DAS BUNDESMINISTERIUM FÜR WIRTSCHAFT UND ENERGIE,
Inventor： MITSCHANG, Lorenz , KILIAN, Wolfgang , KORCHAK, Sergey
Abstract: Die Erfindung betrifft ein Verfahren zum quantitativen Bestimmen einer Wirtsmolekül-Konzentration (Ctot) an Wirtsmolekülen (10), mit den Schritten: (a) Einbringen von hyperpolarisiertem Xenon in eine Lösung (16) von Wirtsmolekülen (10), sodass eine xenonhaltige Lösung (16) entsteht, die gelöstes Xenon und Xenon in einem Wirtsmolekül-Xenon-Komplex (14) mit einem Wirtsmolekül (10) enthält, (b) Bestrahlen der xenonhaltigen Lösung (16) mit elektromagnetischer Depolarisierungs-Strahlung (18) mit einer Wirtskomplex-Frequenz (fw) zum zumindest teilweisen selektiven Depolarisieren von Xenon im Wirtsmolekül-Xenon-Komplex (14), und (c) danach Messen einer Signalintensität (S) eines Hochfrequenzsignals (20) zumindest in einem Frequenzintervall um eine Resonanz-Frequenz (fR) des gelösten Xenons, zu zumindest zwei unterschiedlichen Zeitpunkten der Bestrahlung (t). Erfindungsgemäß ist (d) das Bestrahlen von xenonhaltigen Lösungen (16) unterschiedlicher Xenon-Konzentrationen (ρ) gelösten Xenons mit Depolarisierungs-Strahlung (18) unterschiedlicher Bestrahlungsamplituden (ν) und -zeiten (t) und Erfassen der jeweiligen Signalintensitäten (S(ρ,ν,t)) und (e) das Bestimmen der Wirtsmolekül-Konzentration (Ctot) aus den Signalintensitäten (S(ρ,ν,t)), Xenon- Konzentrationen (ρ) gelösten Xenons, Bestrahlungsamplituden (ν) und -zeiten (t) vorgesehen.
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公开(公告)号：WO2023280556A1
公开(公告)日：2023-01-12
申请号：PCT/EP2022/066687
申请日：2022-06-20
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： PYNE, Alexander, James , GRACE, Kevin
Abstract: An apparatus for making an electrical connection between a superconducting component disposed in a cryogenic chamber and an electrical device disposed outside the cryogenic chamber is described. The apparatus includes a coil comprising a plurality of helical loops and disposed in the cryogenic chamber; and an actuator configured to compress and expand the coil between a first state and a second state. In the first state, the coil has a first electrical resistance and a first thermal conductance and in the second state the coil has a second electrical resistance and a second thermal conductance.
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Patent Agency Ranking
公开(公告)号：WO2022261742A1
公开(公告)日：2022-12-22
申请号：PCT/CA2021/050824
申请日：2021-06-17
Applicant: ELEKTA LIMITED
Inventor： HÉBERT, François , TREMBLAY, Sebastien
Abstract: Systems and methods are disclosed for performing operations comprising: receiving a plurality of training medical images used to train a machine learning technique; applying a model to the plurality of training medical images to generate a distribution representation of the plurality of training medical images; computing a first distance between a given training medical image in the plurality of training medical images and the distribution representation; computing a second distance between a new medical image and the distribution representation; and computing a quality factor indicating a measure of similarity between a new medical image and the plurality of medical images as a function of the first distance and the second distance.
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公开(公告)号：WO2022229728A1
公开(公告)日：2022-11-03
申请号：PCT/IB2022/052620
申请日：2022-03-22
Applicant: UNIVERSITÄT BERN
Inventor： SLOTBOOM, Johannes , WENG, Guodong
IPC: G01R33/485 , G01R33/565 , G01R33/28 , G01R33/483 , G01R33/561 , G01R33/48 , G01R33/46
Abstract: A method for generating 2π-refocusing pulses for magnetic resonance spectroscopy (MRS), and for performing spectral editing of MRS data using differential custom bandpass editing. Acquisition may be performed using echo-planar spectroscopic imaging (EPSI), for example. The 2π-refocusing is achieved using chemical-shift-selective adiabatic 2π-refocusing pulses, without spatial-selective (e.g. slice-selective) refocusing. The spectral editing method uses two data sets with different bandpass ('full' and 'partial') editing spectra, and takes the difference of the two edited spectra. The approach lends itself to 3D spectroscopy at B0 of 7 T or higher, and permits whole brain J-coupled metabolite editing (e.g. 2HG or GABA), with greatly reduced specific absorption rate, shorter repetition time, minimal chemical-shift displacement artefacts (CDSAs), robustness to B0-inhomogeneity and indifference to B1+-inhomogeneity compared with existing spatial-selective methods, such as MEGA.
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公开(公告)号：WO2022170745A1
公开(公告)日：2022-08-18
申请号：PCT/CN2021/111527
申请日：2021-08-09
Abstract: 一种磁场增强组件和磁场增强器件(80)，磁场增强组件具有两个外接电容及开关控制电路，开关控制电路用于在射频发射阶段导通，在射频接收阶段断开，可以降低或避免磁场增强组件所在的回路在射频发射阶段的失谐程度，使在使用磁场增强组件时和使用磁场增强组件前，磁共振系统中的受测区域磁场强度相同，因此在射频发射阶段，磁共振系统中的受测区域的磁场强度保持前后一致，能够有效降低磁场增强对人体的不良影响。
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公开(公告)号：WO2022027095A1
公开(公告)日：2022-02-10
申请号：PCT/AU2021/050846
申请日：2021-08-03
Applicant: THE UNIVERSITY OF QUEENSLAND
Inventor： LIU, Feng , CROZIER, Stuart , LI, Mingyan , WEBER, Ewald , DESTRUEL, Aurélien , JIN, Jin
Abstract: A multi-modal antenna for use in magnetic resonance applications, the multi-modal antenna including an elongate first conductive element, an elongate second conductive element at least partially aligned with and spaced from the first conductive element and a dielectric material at least partially separating the first and second conducting elements so that the first and second conductive elements are electromagnetically coupled and/or electrically connected, and wherein at least one of the first and second conducting elements are configured to be electromagnetically coupled and/or electrically connected to an RF system so that the multi-modal antenna can at least one of transmit and receive RF electromagnetic signals for performing magnetic resonance imaging or spectroscopy.
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公开(公告)号：WO2022022959A1
公开(公告)日：2022-02-03
申请号：PCT/EP2021/068789
申请日：2021-07-07
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： WEISS, Steffen , LEUSSLER, Christoph, Günther
Abstract: A system (SYS) and related method for supporting MR imaging. The system (SYS) comprises a logic (CL) to receive a measurement from RF sensors (SS1-8) arrangeable outside a bore (BR) of an MR imaging apparatus (IA). The logic processes the measurement to establish i) whether there is at least one surface RF coil present that is not electrically coupled to circuity (SPC) of the MR imaging apparatus (IA) and/or ii) to localize at least one surface RF coil on or at a patient table (PT) of the MR imaging apparatus.
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