Methods and apparatus for inter-process communication are provided. A circuit may have a plurality of clusters, and at least one cluster may have a computation element (CE), a memory operatively coupled with the CE, and an autonomic transport system (ATS) block operatively coupled with the CE and the memory. The ATS block may be configured to perform inter-process communication (IPC) for the at least one cluster. In one embodiment, the ATS block may transfer a message to a different cluster based on a request from the CE. In another embodiment, the ATS block may receive a message by allocating a buffer in the memory and write the message into the buffer. The ATS block may also be configured to manage synchronization and schedule tasks for the CE.