Invention Grant
- Patent Title: Humanized and affinity matured antibodies to FcRH5 and methods of use
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Application No.: US16395009Application Date: 2019-04-25
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Publication No.: US11192950B2Publication Date: 2021-12-07
- Inventor: Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Clark & Elbing LLP
- Agent Thomas J. Takara
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12P21/06 ; C12P21/04 ; C12N5/00 ; C12N5/16 ; C12N1/20 ; C07K16/28 ; A61K47/68 ; A61K39/395 ; A61K45/06 ; C07K16/30 ; G01N33/574 ; C07K16/00 ; A61K39/00
Abstract:
The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
Public/Granted literature
- US20190315860A1 HUMANIZED AND AFFINITY MATURED ANTIBODIES TO FcRH5 AND METHODS OF USE Public/Granted day:2019-10-17
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