公开(公告)号：US20240383984A1

公开(公告)日：2024-11-21

申请号：US18675452

申请日：2024-05-28

Applicant: Genentech, Inc.

Inventor： Isidro Hotzel ,  Teemu T. Junttila ,  Ji Li ,  Justin Scheer ,  Danielle Dicara ,  Diego Ellerman ,  Christoph Spiess ,  Paul J. Carter

IPC: C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  A61K45/06 ,  A61K47/68 ,  C07K16/30 ,  G01N33/574

Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.

公开(公告)号：US12030947B2

公开(公告)日：2024-07-09

申请号：US17514824

申请日：2021-10-29

Applicant: Genentech, Inc.

Inventor： Isidro Hotzel ,  Teemu T. Junttila ,  Ji Li ,  Justin Scheer ,  Danielle Dicara ,  Diego Ellerman ,  Christoph Spiess ,  Paul J. Carter

IPC: A61K39/395 ,  A61K39/40 ,  A61K45/06 ,  A61K47/68 ,  C07K16/28 ,  C07K16/30 ,  G01N33/574 ,  A61K39/00 ,  C07K16/00

CPC classification number: C07K16/283 ,  A61K39/39558 ,  A61K45/06 ,  A61K47/6849 ,  A61K47/6851 ,  C07K16/2809 ,  C07K16/2827 ,  C07K16/30 ,  G01N33/57492 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/52 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/62 ,  C07K2317/73 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94 ,  G01N2333/70535

Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.

公开(公告)号：US11192950B2

公开(公告)日：2021-12-07

申请号：US16395009

申请日：2019-04-25

Applicant: Genentech, Inc.

Inventor： Isidro Hotzel ,  Teemu T. Junttila ,  Ji Li ,  Justin Scheer ,  Danielle Dicara ,  Diego Ellerman ,  Christoph Spiess ,  Paul J. Carter

IPC: C07H21/02 ,  C07H21/04 ,  C12P21/06 ,  C12P21/04 ,  C12N5/00 ,  C12N5/16 ,  C12N1/20 ,  C07K16/28 ,  A61K47/68 ,  A61K39/395 ,  A61K45/06 ,  C07K16/30 ,  G01N33/574 ,  C07K16/00 ,  A61K39/00

Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.

公开(公告)号：US10435471B2

公开(公告)日：2019-10-08

申请号：US14313822

申请日：2014-06-24

Applicant: Genentech, Inc.

Inventor： Allen J. Ebens ,  Meredith C. Hazen ,  Jo-Anne Hongo ,  Jennifer W. Johnston ,  Teemu T. Junttila ,  Ji Li ,  Andrew G. Polson

IPC: C07K16/00 ,  C12P21/08 ,  C07K17/00 ,  A61K39/395 ,  A61K39/40 ,  C07K16/28 ,  A61K51/10 ,  A61K47/68 ,  C07K1/00 ,  A61K39/00

Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.

公开(公告)号：US10323094B2

公开(公告)日：2019-06-18

申请号：US15184690

申请日：2016-06-16

Applicant: Genentech, Inc.

Inventor： Isidro Hotzel ,  Teemu T. Junttila ,  Ji Li ,  Justin Scheer ,  Danielle DiCara ,  Diego Ellerman ,  Christoph Spiess ,  Paul J. Carter

IPC: C07K16/00 ,  C12P21/08 ,  A61K39/395 ,  A61K39/40 ,  A61K39/42 ,  C07K16/28 ,  A61K45/06 ,  C07K16/30 ,  G01N33/574 ,  A61K47/68 ,  A61K39/00

Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.

公开(公告)号：US11352431B2

公开(公告)日：2022-06-07

申请号：US16583584

申请日：2019-09-26

Applicant: Genentech, Inc.

Inventor： Allen J. Ebens ,  Meredith C. Hazen ,  Jo-Anne Hongo ,  Jennifer W. Johnston ,  Teemu T. Junttila ,  Ji Li ,  Andrew G. Polson

IPC: C07H21/04 ,  C07H21/02 ,  C12P21/06 ,  C12P21/04 ,  C12N5/02 ,  C12N5/16 ,  C07K16/28 ,  A61K47/68 ,  A61K39/395 ,  A61K51/10 ,  C07K16/00 ,  A61K39/00

Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.

公开(公告)号：US20150098900A1

公开(公告)日：2015-04-09

申请号：US14313822

申请日：2014-06-24

Applicant: Genentech, Inc.

Inventor： Allen J. Ebens ,  Meredith C. Hazen ,  Jo-Anne Hongo ,  Jennifer W. Johnston ,  Teemu T. Junttila ,  Ji Li ,  Andrew G. Polson

IPC: C07K16/28 ,  A61K39/395 ,  A61K51/10 ,  A61K47/48

CPC classification number: C07K16/283 ,  A61K39/395 ,  A61K39/3955 ,  A61K47/6803 ,  A61K47/6849 ,  A61K47/6879 ,  A61K47/6889 ,  A61K51/1045 ,  A61K2039/505 ,  C07K16/2896 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/56

Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.

Abstract translation: 本发明提供抗FcRH5抗体和免疫缀合物及其使用方法。