发明申请
US20050239054A1 Method and compositions for identifying anti-HIV therapeutic compounds
审中-公开
用于鉴定抗HIV治疗化合物的方法和组合物
- 专利标题： Method and compositions for identifying anti-HIV therapeutic compounds
- 专利标题（中）： 用于鉴定抗HIV治疗化合物的方法和组合物
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申请号： US10740694申请日： 2003-12-22
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公开(公告)号： US20050239054A1公开(公告)日： 2005-10-27
- 发明人: Murty Arimilli , Mark Becker , Gabriel Birkus , Clifford Bryant , James Chen , Xiaowu Chen , Tomas Cihlar , Azar Dastgah , Eugene Eisenberg , Maria Fardis , Marcos Hatada , Gong-Xin He , Haolun Jin , Choung Kim , William Lee , Christopher Lee , Kuei-Ying Lin , Hongtao Liu , Richard MacKman , Martin McDermott , Michael Mitchell , Peter Nelson , Hyung-Jung Pyun , Tanisha Rowe , Mark Sparacino , Sundaramoorthi Swaminathan , James Tario , Jianying Wang , Matthew Williams , Lianhong Xu , Zheng-Yu Yang , Richard Yu , Jiancun Zhang , Lijun Zhang
- 申请人： Murty Arimilli , Mark Becker , Gabriel Birkus , Clifford Bryant , James Chen , Xiaowu Chen , Tomas Cihlar , Azar Dastgah , Eugene Eisenberg , Maria Fardis , Marcos Hatada , Gong-Xin He , Haolun Jin , Choung Kim , William Lee , Christopher Lee , Kuei-Ying Lin , Hongtao Liu , Richard MacKman , Martin McDermott , Michael Mitchell , Peter Nelson , Hyung-Jung Pyun , Tanisha Rowe , Mark Sparacino , Sundaramoorthi Swaminathan , James Tario , Jianying Wang , Matthew Williams , Lianhong Xu , Zheng-Yu Yang , Richard Yu , Jiancun Zhang , Lijun Zhang
- 主分类号： C12N9/99
- IPC分类号： C12N9/99 ; A61K31/4155 ; A61K31/66 ; A61K31/665 ; A61K31/675 ; A61P31/18 ; A61P43/00 ; C07D213/75 ; C07D213/85 ; C07D231/12 ; C07D231/20 ; C07D233/42 ; C07D239/48 ; C07D239/80 ; C07D243/04 ; C07D265/18 ; C07D307/68 ; C07D401/06 ; C07D403/06 ; C07D471/14 ; C07D491/04 ; C07F20060101 ; C07F9/02 ; C07F9/38 ; C07F9/40 ; C07F9/44 ; C07F9/58 ; C07F9/62 ; C07F9/645 ; C07F9/6506 ; C07F9/6509 ; C07F9/6512 ; C07F9/653 ; C07F9/6533 ; C07F9/655 ; C07F9/6558 ; C07F9/6561 ; C07F9/6584 ; C12N9/16 ; C12Q1/18 ; C12Q1/37 ; C12Q1/44 ; C12Q1/70 ; G01N33/04 ; G01N33/50
摘要：
Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.
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