- 专利标题： Amido compounds and their use as pharmaceuticals
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申请号： US11122309申请日： 2005-05-04
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公开(公告)号： US20050282858A1公开(公告)日： 2005-12-22
- 发明人: Wenqing Yao , Jincong Zhuo , Meizhong Xu , Brian Metcalf , Chunhong He , Ding-Quan Qian , Colin Zhang
- 申请人： Wenqing Yao , Jincong Zhuo , Meizhong Xu , Brian Metcalf , Chunhong He , Ding-Quan Qian , Colin Zhang
- 主分类号： A61K31/401
- IPC分类号： A61K31/401 ; A61K31/445 ; C07D207/06 ; C07D207/08 ; C07D207/10 ; C07D207/12 ; C07D207/14 ; C07D207/16 ; C07D207/263 ; C07D207/30 ; C07D209/08 ; C07D209/42 ; C07D209/44 ; C07D209/52 ; C07D209/62 ; C07D209/70 ; C07D211/16 ; C07D211/18 ; C07D211/22 ; C07D211/34 ; C07D211/46 ; C07D211/48 ; C07D211/52 ; C07D211/58 ; C07D211/64 ; C07D211/66 ; C07D211/70 ; C07D213/38 ; C07D217/06 ; C07D217/26 ; C07D221/00 ; C07D221/20 ; C07D223/02 ; C07D223/04 ; C07D231/04 ; C07D295/185 ; C07D333/34 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D401/14 ; C07D403/04 ; C07D405/04 ; C07D405/14 ; C07D413/10 ; C07D413/14 ; C07D417/04 ; C07D471/04 ; C07D471/10 ; C07D487/04 ; C07D487/08 ; C07D487/10 ; C07D491/10 ; C07D491/20 ; C07D493/10 ; C07D495/04 ; C07D498/20 ; C07D513/10
摘要：
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
公开/授权文献
- US07304081B2 Amido compounds and their use as pharmaceuticals 公开/授权日：2007-12-04
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