PEPTIDE DEFORMYLASE INHIBITORS
    95.
    发明公开
    PEPTIDE DEFORMYLASE INHIBITORS 审中-公开
    PEPTID-脱,缝边

    公开(公告)号:EP1732907A1

    公开(公告)日:2006-12-20

    申请号:EP05715122.7

    申请日:2005-03-22

    申请人: Arpida A/S

    CPC分类号: C07D279/16

    摘要: Benzothiazine compounds of the general formula (I) and pharmaceutically acceptable salts or esters thereof are peptide deformylase inhibitors useful in the treatment or prevention of infections and other diseases in which peptide deformylases are involved, especially in the treatment of bacterial and parasitic infections, for example infections fully or partly caused by microorganisms belonging to Staphylococcus, Enterococcus, Streptococcus, Haemophilus, Moraxella, Escherichia, Mycobacterium, Mycoplasma, Pseudomonas, Chlamydia, Rickettsia, Klebsiella, Shigella, Salmonella, Bordetella, Clostridium, Helicobacter, Campylobacter, Legionella or Neisseria.

    摘要翻译: 通式(I)的苯并噻嗪化合物及其药学上可接受的盐或酯是可用于治疗或预防涉及肽变形酶的感染和其它疾病,特别是治疗细菌和寄生虫感染的肽变性酶抑制剂,例如 感染完全或部分由属于葡萄球菌,肠球菌,链球菌,嗜血杆菌,莫拉氏菌,大肠杆菌,分枝杆菌,支原体,假单胞菌,衣原体,立克次体,克雷伯杆菌,志贺氏菌,沙门氏菌,博德特氏菌,梭菌属,幽门螺杆菌,弯曲菌属,军团菌或奈瑟球菌的微生物所致。

    Bridged charge transport materials having a central sulfur atom linkage
    100.
    发明公开
    Bridged charge transport materials having a central sulfur atom linkage 有权
    VerbrückteLadungstransportmaterialien mit zentraler Schwefelatombindung

    公开(公告)号:EP1600821A1

    公开(公告)日:2005-11-30

    申请号:EP05252694.4

    申请日:2005-04-29

    摘要: The present invention provides organophotoreceptors comprising an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising:

    (a) a charge transport material having the formula
       where Z 1 and Z 2 comprise, each independently, a bond, a vinyl group, a - CR 1 =N-NR 2 - group, or a -CR 3 =N-N=CR 4 - group;
       Y 1 and Y 2 comprise, each independently, an aromatic group;
       X 1 and X 2 are, each independently, a linking group;
       W 1 and W 2 are, each independently, a -(CH 2 ) n - group or a -(CH 2 ) n-1 -C(=O)-group, where n is an integer between 1 and 10, inclusive;
       Q 1 and Q 2 are, each independently, O, S, or NR; and
       R 1 , R 2 , R 3 , R 4 , R, R', and R" comprise, each independently, H, an alkyl group, an alkenyl group, an alkynyl group, an acyl group, a heterocyclic group, or an aromatic group; and
    (b) a charge generating compound.

    Corresponding electrophotographic apparatuses and imaging methods are described, as are charge transport materials and methods of preparing a bridged charge transport material.

    摘要翻译: 本发明提供了在导电基底上包含导电基底和光电导元件的有机光感受器,光电导元件包括:(a)具有式CHEM的电荷传输材料,其中Z1和Z2各自独立地包含键, 乙烯基,-CR1 = N-NR2-基,或-CR3 = NN = CR4-基; Y1和Y2各自独立地包含芳族基团; X1和X2各自独立地为连接基团; W1和W2各自独立地为 - (CH2)n-基或 - (CH2)n-1-C(= O) - 基,其中n是1和10之间的整数,包括1和10; Q1和Q2各自独立地为O,S或NR; 并且R 1,R 2,R 3,R 4,R 3,R'和R“各自独立地为H,烷基,烯基,炔基,酰基,杂环基或芳族基; (b)电荷产生化合物。描述相应的电子照相设备和成像方法,电荷输送材料和制备桥接电荷输送材料的方法。