公开(公告)号：EP2880438A1

公开(公告)日：2015-06-10

申请号：EP13745095.3

申请日：2013-08-05

Applicant: Commissariat à l'Énergie Atomique et aux Énergies Alternatives ,  Analytical Pixels Technology - Apix Technology

Inventor： DURAFFOURG, Laurent ,  ANDREUCCI, Philippe ,  TASSETTI, Charles-Marie ,  COLINET, Eric ,  PUGET, Pierre ,  WHITING, Joshua ,  STEVENS, Peter Thomas ,  PETITJEAN, Mélanie

IPC: G01N30/72 ,  H01J49/00 ,  H01J49/40

CPC classification number: G01N30/7206 ,  G01N2030/025 ,  H01J49/0018 ,  H01J49/405

Abstract: The invention concerns a gas analysis system comprising, from upstream to downstream: - a module (SEP) for separating at least a portion of the species contained in the gas to be analysed, comprising at least one microcapillary column (GC) for gas phase chromatography, and - a time-of-flight mass spectrometer (TOFMS) coupled to said separation module, said spectrometer comprising a source of ions (MS1, MS2) adapted to ionise at least a portion of said species and to emit an ion beam, and a free-flight zone (MS4) for said ions, said mass spectrometer (TOFMS) being arranged in the volume of at least one substrate and comprising a micro-reflectron (R) arranged between the source (MS1, MS2) and the free flight zone (MS4), a wall (R1) of said micro-reflectron comprising a layer made from a resistive material designed to be polarised between at least two regions so as to create a continuous electrostatic field gradient in said reflectron.

公开(公告)号：EP2758983A2

公开(公告)日：2014-07-30

申请号：EP12769352.1

申请日：2012-09-20

Applicant: The University of Sussex

Inventor： VERDU GALIANA, Jose Luis

IPC: H01J49/42 ,  H01J49/00

CPC classification number: H01J49/20 ,  B82Y10/00 ,  H01J49/0018 ,  H01J49/0031 ,  H01J49/38 ,  H01J49/422

Abstract: An ion trap comprising: a first array of magnetic elements arranged to generate a first magnetic field with a degree of homogeneity; and an array of electrodes arranged to generate an electrostatic field including a turning point in electrical potential at a location where the magnetic field has a substantially maximum degree of homogeneity; wherein the array of electrodes is planar and parallel to the direction of the magnetic field at the location; and wherein a primary first magnetic element is arranged to generate a first component of the first magnetic field and other first magnetic elements are arranged to generate compensating components of the first magnetic field that reduce the gradient, the curvature and higher order derivatives of the first component of the first magnetic field at the location where the first magnetic field has the substantially maximum degree of homogeneity.

Abstract translation: 1。一种离子阱，包括：第一磁性元件阵列，所述第一磁性元件阵列布置成产生具有一定程度均匀性的第一磁场; 以及布置成产生静电场的电极阵列，所述静电场包括在所述磁场具有基本上最大均匀度的位置处的电势转折点; 其中所述电极阵列是平面的并且平行于所述位置处的所述磁场的方向; 并且其中初级第一磁性元件被布置成生成第一磁场的第一分量，并且其他第一磁性元件被布置为生成第一磁场的补偿分量，该补偿分量减小第一分量的梯度，曲率和高阶导数 在第一磁场具有基本最大均匀度的位置处的第一磁场的位置。

公开(公告)号：EP2532020A1

公开(公告)日：2012-12-12

申请号：EP11740241.2

申请日：2011-01-31

Applicant: Thermo Finnigan LLC

Inventor： MAKAROV, Alexander, A. ,  WOUTERS, Eloy, R.

IPC: H01J49/10 ,  H01J49/26

CPC classification number: H01J49/167 ,  H01J49/0018 ,  Y10T29/49423 ,  Y10T29/49433

Abstract: An electrospray ion source for a mass spectrometer includes an electrode comprising at least a first plurality of protrusions protruding from a base, each protrusion of the at least a first plurality of protrusions having a respective tip; a conduit for delivering an analyte- bearing liquid to the electrode; and a voltage source, wherein, in operation of the electrospray ion source, the analyte-bearing liquid is caused to move, in the presence of a gas or air, from the base to each protrusion tip along a respective protrusion exterior so as to form a respective stream of charged particles emitted towards an ion inlet aperture of the mass spectrometer under application of voltage applied to the electrode from the voltage source.

Abstract translation: 用于质谱仪的电喷雾离子源包括电极，其包括从基底突出的至少第一多个突起，所述至少第一多个突起的每个突起具有相应的末端; 用于将分析物承载液体输送到电极的导管; 以及电压源，其中，在电喷雾离子源的操作中，使有分析物的液体在气体或空气的存在下沿着相应的突起外部从基部移动到每个突起尖端，以形成 在施加从电压源施加到电极的电压下，向质谱仪的离子入口孔发射的相应的带电粒子流。

公开(公告)号：EP2506287A1

公开(公告)日：2012-10-03

申请号：EP12001634.0

申请日：2012-03-09

Applicant: KROHNE Messtechnik GmbH

Inventor： Deilmann, Michael, Dr. ,  Gerding, Michael, Dr.

IPC: H01J49/02 ,  H01J49/34 ,  H01J49/00

CPC classification number: H01J49/34 ,  H01J49/0018 ,  H01J49/022

Abstract: Beschrieben und dargestellt ist eine Ansteuervorrichtung für einen synchronous ion shield Massenseparator mit einem Referenzoszillator (1), einem Direct Digital Synthesizer (2), einem Tiefpass (3) und einem Komparator (4), wobei der synchronous ion shield Massenseparator eine kammförmige Separationselektrode (6) aufweist, wobei der Referenzoszillator (1) dem Direct Digital Synthesizer (2) eine Referenzfrequenz zur Verfügung stellt, das von dem Direct Digital Synthesizer (2) erzeugte Ausgangssignal von dem Tiefpass (3) gefiltert wird und das Ausgangssignal des Tiefpasses (3) von dem Komparator (4) verarbeitet wird.
Eine Ansteuervorrichtung, die flexibel einsetzbar und kostengünstig ist, wird erfindungsgemäß dadurch realisiert, dass das Ausgangssignal des Komparators (4) von einem programmierbaren Element (11) in eine der Anzahl der Zinken (7) der kammförmigen Separationselektrode (6) entsprechende Anzahl von Ausgangssignalen umgewandelt wird.

Abstract translation: 控制装置具有参考振荡器（1），直接数字合成器（2），低通滤波器（3）和比较器（4）。 同步离子屏蔽质量分离器具有梳状分离电极（6）。 直接数字合成器产生参考频率。 从比较器处理低通滤波器的输出信号。 比较器的输出信号被可编程元件（11）转换成对应于梳形分离电极的多个齿（7）的多个输出信号。 包括用于控制同步离子屏蔽质量分离器的方法的独立权利要求。

公开(公告)号：EP2502257A1

公开(公告)日：2012-09-26

申请号：EP10830294.4

申请日：2010-11-16

Applicant: Biomotif AB

Inventor： LAVOLD, Thorleif ,  ASTORGA WELLS, Juan

IPC: H01J49/04 ,  C01B4/00 ,  C01B5/02 ,  G01N33/68

CPC classification number: C07K1/13 ,  B01D15/361 ,  G01N27/26 ,  G01N30/00 ,  G01N30/06 ,  G01N30/7266 ,  G01N30/96 ,  G01N2001/4011 ,  G01N2001/4016 ,  G01N2030/067 ,  G01N2030/146 ,  G06F19/703 ,  H01J49/00 ,  H01J49/0018 ,  H01J49/04 ,  H01J49/0431 ,  H01J49/165 ,  Y10T436/24

Abstract: Apparatus and methods to perform hydrogen/deuterium exchange using semipermeable membranes are described. The system has two channels separated by a semipermeable membrane. One channel comprises a flow carrying the analyte of interest, and the second channel comprises a solution comprising a deuterated solvent (e.g. deuterium oxide). The system does not require an external electric field gradient across the membrane to perform the hydrogen-deuterium exchange procedure. The present invention facilitates sample and reagent handling as well as simplifies manufacture of devices and/or instrumentation related to deuterium exchange. Further described is a chemical analysation device for analysing chemical compositions and/or compounds, and a method for analysing chemical compounds and a computer program product for inducing a computer to perform steps in the method. Also described is a method for analyzing interactions between analytes and charged molecules, and calculating binding coefficients of the analytes with respect to the charged molecules.

公开(公告)号：EP2390899A1

公开(公告)日：2011-11-30

申请号：EP10164101.7

申请日：2010-05-27

Applicant: Universität Innsbruck

Inventor： Kumph, Muir

IPC: H01J49/00 ,  H01J49/42 ,  H01J49/06

CPC classification number: H01J49/0018 ,  B82Y10/00 ,  G06N99/002 ,  H01J49/06 ,  H01J49/4295

Abstract: An apparatus and a method for trapping charged particles and performing controlled interactions between them are provided. The apparatus includes a substrate and RF electrodes and dedicated DC electrodes arranged on the substrate and configured to generate a trapping potential for trapping the charged particles above the substrate. The RF and dedicated DC electrodes include at least one RF trapping electrode configured to be driven with an RF voltage for contributing to the trapping potential, an array of two or more trapping site DC electrodes configured to be biased with a DC voltage for contributing to the trapping potential, and a first individually drivable RF control electrode (250, 251, 252, 253) arranged between a first pair out of the two or more trapping site DC electrodes. The first RF control electrode is configured to be individually driven by an adjustable RF voltage such that the trapping potential above and between the first pair of trapping site DC electrodes forms separate charged particle traps adapted for trapping charged particles therein if the adjustable RF voltage takes a first value, and forms a charged particle interaction trap adapted for performing controlled interactions between charged particles if the adjustable RF voltage takes a second value.

Abstract translation: 本发明提供一种装置和用于捕获带电颗粒和执行它们之间的受控的相互作用的方法。 该装置包括一个基底和RF电极和专用DC电极设置在基片并构造成产生用于捕集基板上方的带电粒子俘获电位。 RF和DC专用电极包括配置为与RF电压加以驱动以有助于俘获电位到两个或更多个捕获区DC电极构成的阵列，以利用DC电压来偏置至少一个RF俘获电极为有助于 捕获电位，并且第一对之间设置了两个或更多个捕获区DC电极的第一驱动独立RF控制电极（250，251，252，253）。 第一RF控制电极被配置为通过在检查做俘获电位之上和所述第一对俘获点DC电极形式之间可调RF电压被单独驱动分离angepasst用于捕集带电粒子阱的带电粒子。其中，如果可调整的RF电压取 firstValue，并形成用于带电粒子之间进行受控的相互作用，如果可调整的RF电压取第二值的带电粒子相互作用陷阱angepasst。

公开(公告)号：EP2259996B1

公开(公告)日：2011-10-19

申请号：EP09717253.0

申请日：2009-02-17

Applicant: Bayer Technology Services GmbH

Inventor： HAUSCHILD, Jan-Peter ,  WAPELHORST, Eric ,  MÜLLER, Jörg

IPC: B81C3/00

CPC classification number: B81C3/008 ,  B81C2203/051 ,  H01J43/246 ,  H01J49/0018 ,  H01L2924/0002 ,  H01L2924/00

Abstract: The objects of the present invention are a fixture for use in microsystems, particularly for the self-adjusting installation and fixture of micro-channel plates, and a device, comprising at least one fixture according to the invention and a micro-channel plate. The fixture according to the invention comprises – structures made of a conductive material for accommodating a component of the microsystem, which are mounted on a non-conductive carrier, - spring-loaded structures, which position the component in a self-adjusting manner and simultaneously carry out electrical contacting, and - at least one stop for positioning the component.

公开(公告)号：EP1872850B1

公开(公告)日：2010-06-16

申请号：EP07252601.5

申请日：2007-06-27

Applicant: JEOL Ltd.

Inventor： Sakura, Satoshi

IPC: B01J19/00 ,  B01L3/00

CPC classification number: B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00831 ,  B01J2219/00858 ,  B01J2219/00862 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00952 ,  B01L3/502707 ,  B01L2200/025 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0887 ,  B01L2400/0487 ,  G01R33/302 ,  G01R33/307 ,  H01J49/0018 ,  H01J49/165

公开(公告)号：EP2193098A1

公开(公告)日：2010-06-09

申请号：EP08753588.6

申请日：2008-05-19

Applicant: Electronics and Telecommunications Research Institute

Inventor： YU, Han Young ,  KIM, Byung Hoon ,  KIM, An Soon ,  BAEK, In Bok ,  AH, Chil Seong ,  YANG, Jong Heon ,  PARK, Chan Woo ,  AHN, Chang Geun

IPC: B82B1/00

CPC classification number: H01J49/4205 ,  B81B7/0025 ,  B81B2201/0214 ,  B81B2201/0271 ,  B82Y10/00 ,  B82Y40/00 ,  G01N2291/0257 ,  H01J49/0018 ,  H01L29/0673 ,  H01L29/7613 ,  H01L29/775 ,  H03H2009/02314

Abstract: Provided are three-dimensional (3D) nanodevices including 3D nanostructures. The 3D nanodevice includes at least one nanostructure, each nanostructure including an oscillation portion floating over a substrate and support portions for supporting both lengthwise end portions of the oscillation portion, supports disposed on the substrate to support the support portions of each of the nanostructures, at least one controller disposed at an upper portion of the substrate, a lower portion of the substrate, or both the upper and lower portions of the substrate to control each of the nanostructures, and a sensing unit disposed on each of the oscillation portions to sense an externally supplied adsorption material. Thus, unlike in a typical planar device, generation of impurities between a nanodevice and a substrate can be reduced, and mechanical vibration can be caused. In particular, since 3D nanostructures have mechanical and electrical characteristics, 3D nanodevices including new 3D nanostructures can be provided using nano-electro-mechanical systems (NEMS). Also, a single electron device, a spin device, or a single electron transistor (SET)-field effect transistor (FET) hybrid device can be formed using a simple process unlike in planar devices.

公开(公告)号：EP1756861A4

公开(公告)日：2009-05-27

申请号：EP05747617

申请日：2005-05-06

Applicant: STILLWATER SCIENT INSTR ,  UNIV MAINE

Inventor： SMITH ROSEMARY ,  COLLINS SCOTT ,  FREDERICK BRIAN G ,  LEGORE LAWRENCE J

IPC: H01L23/52 ,  H01J9/14 ,  H01J49/06 ,  H01L21/46 ,  H01L23/34

CPC classification number: H01J9/14 ,  H01J49/0018 ,  H01J49/061 ,  H01L2924/0002 ,  Y10S438/977 ,  H01L2924/00

Abstract: A grid structure and method for manufacturing the same. The grid is used for gating a stream of charged particles in certain types of particle measurement instruments, such as ion mobility spectrometers and the like. The methods include various microfabrication techniques for etching and/or depositing grid structure materials on a silicon substrate.