公开(公告)号：EP1890702A1

公开(公告)日：2008-02-27

申请号：EP06742947.2

申请日：2006-05-17

申请人： Bayer HealthCare AG

发明人： HENDRIX, Martin ,  WUNDER, Frank ,  TERSTEEGEN, Adrian ,  STASCH, Johannes-Peter ,  WUTTKE, Martina

IPC分类号： A61K31/513 ,  A61P9/00 ,  A61P9/04 ,  A61P9/10 ,  A61P9/12 ,  A61P13/12

CPC分类号： A61K31/513

摘要： The invention relates to the use of cyanopyrimidines for producing medicaments utilized for the treatment of cardiovascular diseases.

公开(公告)号：EP1448530B1

公开(公告)日：2007-10-03

申请号：EP02781305.4

申请日：2002-11-06

申请人： Bayer HealthCare AG

发明人： HENDRIX, Martin ,  BÖSS, Frank-Gerhard ,  ERB, Christina ,  KRÜGER, Joachim ,  LUITHLE, Joachim ,  METHFESSEL, Christoph ,  SCHREIBER, Rudy ,  WIESE, Welf-Burkhard

IPC分类号： C07D215/48 ,  C07D241/46 ,  C07D453/02 ,  A61P25/28 ,  A61K31/47 ,  A61K31/517

CPC分类号： C07D453/02

摘要： The invention relates to novel heteroaryl carboxylic acid amides, a method for producing the same and the use thereof for producing pharmaceuticals for the treatment and/or prophylaxis of diseases and for improving perception, power of concentration, learning ability and/or memory power.

公开(公告)号：EP1461335B1

公开(公告)日：2007-02-28

申请号：EP02793023.9

申请日：2002-12-16

申请人： Bayer HealthCare AG

发明人： HENDRIX, Martin ,  BÖSS , Frank-Gerhard ,  ERB, Christina ,  FLESSNER, Timo ,  VAN KAMPEN, Marja ,  LUITHLE, Joachim ,  METHFESSEL, Christoph ,  WIESE, Welf-Burkhard

IPC分类号： C07D453/02 ,  C07D519/00 ,  A61K31/435

CPC分类号： C07D453/02

摘要： The invention relates to novel 2-heteroarylcarboxylic acid amides, methods for the production thereof in addition to the use thereof for the production of medicaments for the treatment and/or the prophylaxis of illnesses and for the improvement of perception, concentration power, learning power and/or memory power.

公开(公告)号：EP1363912B1

公开(公告)日：2006-05-24

申请号：EP02704706.7

申请日：2002-02-11

申请人： Bayer HealthCare AG

发明人： NIEWÖHNER, Ulrich ,  SCHAUSS, Dagmar ,  KÖNIG, Gerhard ,  HENDRIX, Martin ,  BÖSS, Frank-Gerhard ,  VAN DER STAAY, Franz-Josef ,  SCHREIBER, Rudy ,  SCHLEMMER, Karl-Heinz ,  MORIWAKI, Toshiya ,  NIEWÖHNER, Maria Theresia

IPC分类号： C07D487/04 ,  A61K31/53 ,  A61P25/00 ,  C07D253/06 ,  C07D253/00 ,  C07D235/00

CPC分类号： C07D253/07 ,  C07D487/04

摘要： The invention relates to novel substituted imidazotriazinones, to a method for their production and to the use thereof for producing medicaments, in particular to improve perception, powers of concentration, learning capacity and/or memory retentiveness.

摘要翻译： 本发明涉及新型取代的咪唑并三嗪酮，其制备方法及其用于制备药物的用途，特别是改善知觉，注意力，学习能力和/或记忆保持力的能力。

公开(公告)号：EP1644353A1

公开(公告)日：2006-04-12

申请号：EP04737078.8

申请日：2004-06-21

申请人： Bayer HealthCare AG

发明人： FLESSNER, Timo ,  HENNINGER, Kerstin ,  RAABE, Martin ,  WOLTERING, Elisabeth ,  ZAISS, Siegfried ,  ZIMMERMANN, Katja ,  ZUMPE, Franz ,  KARIG, Gunter ,  HENDRIX, Martin ,  WEBER, Olaf ,  KARTHAUS, Dagmar

IPC分类号： C07D401/12 ,  A61K31/53 ,  C07D413/12 ,  C07D417/12 ,  C07D403/12 ,  C07D409/12 ,  A61P29/00

CPC分类号： C07D401/12 ,  C07D403/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12

摘要： The invention relates to amide-substituted 1,2,4-triazin-5(2H)-ones, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially chronically inflammatory diseases such as rheumatoid diseases, and cardiovascular diseases such as dyslipidemia, arteriosclerosis and coronary heart diseases Formula (I).

公开(公告)号：EP1397363A1

公开(公告)日：2004-03-17

申请号：EP02738089.8

申请日：2002-05-21

申请人： Bayer HealthCare AG

发明人： ALONSO-ALIJA, Cristina ,  GIELEN, Heike ,  HENDRIX, Martin ,  NIEWÖHNER, Ulrich ,  SCHAUSS, Dagmar ,  BISCHOFF, Hilmar ,  BURKHARDT, Nils ,  GEISS, Volker ,  SCHLEMMER, Karl-Heinz ,  CUTHBERT, Nigel, J. ,  FITZGERALD, Mary ,  STURTON, Richard, Graham ,  MICHELS, Martin

IPC分类号： C07D487/04 ,  A61P29/00

CPC分类号： C07D487/04 ,  C07D253/07

摘要： The invention relates to novel 5-Ethyl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases.

摘要翻译： 本发明涉及新的5-乙基 - 咪唑并三嗪酮类，其制备方法及其在药物中的用途， 用于治疗和/或预防炎症过程和/或免疫疾病。

公开(公告)号：EP1910330A1

公开(公告)日：2008-04-16

申请号：EP06754657.2

申请日：2006-07-01

申请人： Bayer HealthCare AG

发明人： ZIMMERMANN, Holger ,  BRÜCKNER, David ,  HENNINGER, Kerstin ,  HENDRIX, Martin ,  RADTKE, Martin

IPC分类号： C07D401/12 ,  C07D409/12 ,  C07D417/12 ,  A61K31/40 ,  A61K31/38

CPC分类号： C07D409/12 ,  C07D401/12 ,  C07D417/12

摘要： The invention relates to heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and to processes for preparing them, to their use for the treatment and/or prophylaxis of diseases, and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, particularly for use as antiviral agents, especially against cytomegaloviruses.

公开(公告)号：EP1732901A1

公开(公告)日：2006-12-20

申请号：EP05715944.4

申请日：2005-03-11

申请人： Bayer HealthCare AG

发明人： ZIMMERMANN, Holger ,  BRÜCKNER, David ,  HEIMBACH, Dirk ,  HENDRIX, Martin ,  HENNINGER, Kerstin ,  HEWLETT, Guy ,  ROSENTRETER, Ulrich ,  KELDENICH, Jörg ,  LANG, Dieter ,  RADTKE, Martin

IPC分类号： C07D233/90 ,  C07D401/12 ,  C07D403/12 ,  A61K31/4164 ,  A61P31/12

CPC分类号： C07D233/90 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12

摘要： The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.

公开(公告)号：EP1534711B1

公开(公告)日：2006-04-19

申请号：EP03792301.8

申请日：2003-08-12

申请人： Bayer HealthCare AG

发明人： HENDRIX, Martin ,  BÖSS, Frank-Gerhard ,  BURKHARDT, Nils ,  ERB, Christina ,  TERSTEEGEN, Adrian ,  VAN KAMPEN, Marja

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P25/00 ,  C07D239/00 ,  C07D231/00

CPC分类号： C07D487/04

摘要： The invention relates to novel phenyl-substituted pyrazolopyrimidines, to a method for the production thereof, and to their use for producing medicaments serving to improve perception, concentration, learning and/or memory.

公开(公告)号：EP1401435B1

公开(公告)日：2006-03-15

申请号：EP02743172.5

申请日：2002-06-10

申请人： Bayer HealthCare AG

发明人： BETZ, Ulrich ,  LAICH, Tobias ,  BENDER, Wolfgang ,  FISCHER, Rüdiger ,  HENDRIX, Martin ,  KLEYMANN, Gerald

IPC分类号： A61K31/426 ,  A61K31/427 ,  A61K9/06 ,  A61P31/12

CPC分类号： A61K31/427 ,  A61K9/0014 ,  A61K9/0048 ,  A61K31/426 ,  A61K47/06 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34

摘要： The invention relates to the topical application of substituted thiazolyl amides in the treatment of herpes infections in humans, to preparations suitable for the topical application and to the production thereof.