公开(公告)号：EP2420208A1

公开(公告)日：2012-02-22

申请号：EP11189020.8

申请日：2006-08-31

申请人： Spinal Kinetics, Inc.

发明人： Reo, Michael L ,  Gittings, Darin C

IPC分类号： A61F2/44

CPC分类号： A61F2/442 ,  A61F2/30742 ,  A61F2/3094 ,  A61F2002/30009 ,  A61F2002/30014 ,  A61F2002/30075 ,  A61F2002/30133 ,  A61F2002/30168 ,  A61F2002/30179 ,  A61F2002/30224 ,  A61F2002/30331 ,  A61F2002/30387 ,  A61F2002/30462 ,  A61F2002/30471 ,  A61F2002/305 ,  A61F2002/30523 ,  A61F2002/3055 ,  A61F2002/30563 ,  A61F2002/30566 ,  A61F2002/30576 ,  A61F2002/30579 ,  A61F2002/30581 ,  A61F2002/30586 ,  A61F2002/30594 ,  A61F2002/30662 ,  A61F2002/30884 ,  A61F2002/30889 ,  A61F2002/30897 ,  A61F2002/30899 ,  A61F2002/30971 ,  A61F2002/443 ,  A61F2002/448 ,  A61F2002/4495 ,  A61F2002/4677 ,  A61F2002/485 ,  A61F2210/0061 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0015 ,  A61F2230/0043 ,  A61F2230/0058 ,  A61F2230/0069 ,  A61F2250/0018 ,  A61F2250/0028

摘要： Prosthetic intervertebral discs, systems including such prosthetic intervertebral discs, and methods for using the same are described. The subject prosthetic discs include upper and lower endplates separated by a compressible core member. The subject prosthetic discs exhibit stiffness in the vertical direction, torsional stiffness, bending stiffness in the saggital plane, and bending stiffness in the front plane, where the degree of these features can be controlled independently by adjusting the components, construction, and other features of the discs.
The upper and lower endplates comprise pluralities of pins extending into recesses (572) in the compressible core member (570), in order to provide a chosen torsional stiffness.

摘要翻译： 描述了假体椎间盘，包括这种假体椎间盘的系统，以及使用该假体椎间盘的方法。 目标人造椎间盘包括由可压缩的核心部件分开的上端板和下端板。 受试人工椎间盘在竖直方向，扭转刚度，矢状面中的弯曲刚度和前平面中的弯曲刚度表现出刚度，其中这些特征的程度可以通过调整组件，构造和其他特征 光盘。 上部和下部端板包括延伸到可压缩芯构件（570）中的凹部（572）中的多个销，以便提供选择的扭转刚度。

公开(公告)号：EP1734907B1

公开(公告)日：2011-08-17

申请号：EP05729648.5

申请日：2005-03-24

申请人： NuVasive, Inc.

发明人： MCLEOD, Alan, Rory, Mor, Pearsalls Limited ,  REAH, Christopher, Pearsalls Limited

IPC分类号： A61F2/44 ,  A61F2/46

CPC分类号： A61F2/441 ,  A61F2/4611 ,  A61F2002/0086 ,  A61F2002/30009 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30242 ,  A61F2002/30324 ,  A61F2002/30462 ,  A61F2002/30588 ,  A61F2002/30601 ,  A61F2002/3093 ,  A61F2002/444 ,  A61F2002/4627 ,  A61F2210/0004 ,  A61F2210/0061 ,  A61F2220/0075 ,  A61F2230/0071 ,  A61F2250/0028 ,  A61F2250/003 ,  A61F2250/0036 ,  A61F2310/00011 ,  A61F2310/00329

摘要： A spinal implant is provided in which the implant includes a porous component (7) and one or more filling elements (22) provided within the porous component. Tissue in-growth is promoted.

公开(公告)号：EP2037843A2

公开(公告)日：2009-03-25

申请号：EP07775883.7

申请日：2007-04-19

申请人： Spinal Kinetics, Inc.

发明人： WISTROM, Elizabeth V. ,  GITTINGS, Darin C. ,  DOLIN, Jeffrey J. ,  REO, Michael L. ,  STEWART, Daren L. ,  AFZAL, Thomas A. ,  ROBINSON, Janine C. ,  FELLENZ, Frank ,  BASS, Elisa ,  CHEE, Uriel Hiram

IPC分类号： A61F2/30 ,  A61F2/44 ,  A61F2/46

CPC分类号： A61F2/4611 ,  A61B2017/0256 ,  A61F2/30742 ,  A61F2/3094 ,  A61F2/442 ,  A61F2/4425 ,  A61F2002/30004 ,  A61F2002/30009 ,  A61F2002/30075 ,  A61F2002/30133 ,  A61F2002/30148 ,  A61F2002/30153 ,  A61F2002/30156 ,  A61F2002/30242 ,  A61F2002/30383 ,  A61F2002/30387 ,  A61F2002/30398 ,  A61F2002/30405 ,  A61F2002/30462 ,  A61F2002/30471 ,  A61F2002/30476 ,  A61F2002/30507 ,  A61F2002/3055 ,  A61F2002/30556 ,  A61F2002/30563 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30586 ,  A61F2002/30588 ,  A61F2002/30784 ,  A61F2002/3082 ,  A61F2002/30884 ,  A61F2002/30904 ,  A61F2002/443 ,  A61F2002/448 ,  A61F2002/4495 ,  A61F2002/4622 ,  A61F2002/4628 ,  A61F2002/4629 ,  A61F2002/485 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0015 ,  A61F2230/0017 ,  A61F2230/0019 ,  A61F2230/0023 ,  A61F2230/0071 ,  A61F2250/0009 ,  A61F2250/0014 ,  A61F2250/0028 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00173 ,  A61F2310/00179

摘要： Prosthetic intervertebral discs and methods for using the same are described. The subject prosthetic discs include upper and lower end plates (110, 120) separated by a compressible core member (130). Fibres (140) or a fibrous material extend between the endplates and hold them together. The core member may be tillable or may be slidably introduced between the endplates. The distance between the endplates may be varied by a threaded mechanism or by shifting the endplates or the core member with respect to each other.

公开(公告)号：EP1951156A2

公开(公告)日：2008-08-06

申请号：EP06838205.0

申请日：2006-11-20

申请人： Ceramatec, Inc.

发明人： AKASH, Akash

IPC分类号： A61F2/28

CPC分类号： A61F2/30 ,  A61F2/3094 ,  A61F2/32 ,  A61F2/34 ,  A61F2/36 ,  A61F2/3662 ,  A61F2002/2817 ,  A61F2002/30009 ,  A61F2002/30011 ,  A61F2002/30014 ,  A61F2002/30018 ,  A61F2002/30322 ,  A61F2002/30677 ,  A61F2002/30777 ,  A61F2002/30784 ,  A61F2002/30911 ,  A61F2002/30915 ,  A61F2002/3092 ,  A61F2002/30925 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/3682 ,  A61F2250/0018 ,  A61F2250/0023 ,  A61F2250/0026 ,  A61F2250/0028 ,  A61F2250/0029 ,  A61F2310/00011 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00047 ,  A61F2310/00077 ,  A61F2310/00083 ,  A61F2310/00131 ,  A61F2310/00137 ,  A61F2310/00179 ,  A61F2310/00185 ,  A61F2310/00197 ,  A61F2310/00203 ,  A61F2310/00215 ,  A61F2310/00221 ,  A61F2310/00227 ,  A61F2310/00233 ,  A61F2310/00239 ,  A61F2310/00275 ,  A61F2310/00281 ,  A61F2310/00287 ,  A61F2310/00293 ,  A61F2310/00305 ,  A61F2310/00317 ,  A61L27/30 ,  A61L27/42 ,  A61L27/56 ,  C04B35/111 ,  C04B35/62218 ,  C04B35/6263 ,  C04B38/008 ,  C04B38/0645 ,  C04B2111/00836 ,  C04B2235/6025 ,  C04B35/00 ,  C04B38/007 ,  C04B35/447 ,  C04B38/0051

摘要： A method and apparatus for adjusting the modulus of elasticity, flexural strength, or porosity of metal and ceramic implants is disclosed in one embodiment of the invention as including a green tape comprising metal or ceramic particles, or a combination thereof, for incorporation into a solid implant structure (44). Apertures (32) are cut in selected regions of the green tape (34) in order to create a desired pore structure in the solid implant structure (44). This pore structure may be designed to give the solid structure (44) a desired modulus of elasticity, flexural strength, or porosity as well as to promote bone ingrowth. The green tape (34) may then be layered in an orientation that will provide the desired pore structure and the metal or ceramic particles and layers may be fused together to create the solid implant structure (44).

公开(公告)号：EP1895946A2

公开(公告)日：2008-03-12

申请号：EP06772214.0

申请日：2006-06-05

申请人： Nuvasive, Inc.

发明人： MCLEOD, Alan Rory, C/O Nuvasive, UK ,  REAH, Christopher, C/O Nuvasive, UK

IPC分类号： A61F2/44 ,  A61B17/56

CPC分类号： A61F2/441 ,  A61F2/30724 ,  A61F2/30767 ,  A61F2/30965 ,  A61F2/442 ,  A61F2/4611 ,  A61F2002/30008 ,  A61F2002/30009 ,  A61F2002/30062 ,  A61F2002/30069 ,  A61F2002/3008 ,  A61F2002/30092 ,  A61F2002/30146 ,  A61F2002/30225 ,  A61F2002/30242 ,  A61F2002/30291 ,  A61F2002/30298 ,  A61F2002/30461 ,  A61F2002/30462 ,  A61F2002/30565 ,  A61F2002/30578 ,  A61F2002/30583 ,  A61F2002/30588 ,  A61F2002/30601 ,  A61F2002/30602 ,  A61F2002/30616 ,  A61F2002/30841 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0085 ,  A61F2220/0075 ,  A61F2230/0017 ,  A61F2230/0069 ,  A61F2230/0071 ,  A61F2230/0091 ,  A61F2250/0017 ,  A61F2250/0028 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61F2310/00329

摘要： Disc prostheses, particularly for use in the lumbar region of the spine are provided. The disc prosthesis includes a core comprising one or more filling elements provided within an inner component of fabric. The inner component is provided within an outer component of fabric. By providing a smooth inner contact surface between the inner component and the core filling, movement between the inner and outer components is facilitated in preference to movement between the inner component and core. Core abrasion is thus avoided. The use of an inner component and an outer component also means that the characteristics of each can be optimised to meet different aims.

公开(公告)号：EP1643941A2

公开(公告)日：2006-04-12

申请号：EP04748721.0

申请日：2004-07-08

申请人： TECHNISCHE UNIVERSITEIT EINDHOVEN ,  RIJKSUNIVERSITEIT GRONINGEN

发明人： HUYGHE, Jacques, Marie, René, Jan ,  VAN DONKELAAR, Corrinus, Cornelis ,  WIJLAARS, Marcelus, Wilhelmus ,  VERKERKE, G.J., Faculteit Medische Wetenschappen ,  Eijkelkamp, M.F., Faculteit Medische Wetenschappen ,  Veldhuizen, A.G., Academisch Ziekenhuis Groningen

IPC分类号： A61F2/44 ,  A61F2/30

CPC分类号： A61F2/442 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2002/30009 ,  A61F2002/30014 ,  A61F2002/30075 ,  A61F2002/4495 ,  A61F2210/0061 ,  A61F2250/0018 ,  A61F2250/0028

摘要： The present application relates to a prosthesis comprising a flexible portion (1) and at least one less flexible portion (2), which flexible portion comprises a fibre-reinforced hydrogel. In addition to that, the application relates to a prosthesis consisting of a fibre-reinforced hydrogel, which prosthesis is intended to replace cartilaginous materials. The application further relates to the use of the prosthesis and to a method for manufacturing the prosthesis. The application furthermore relates to a method of preparing the flexible portion for a prosthesis. Finally, the application relates to a fibre material apparently intended for use in the prosthesis.

公开(公告)号：EP1523963A1

公开(公告)日：2005-04-20

申请号：EP03405751.3

申请日：2003-10-17

申请人： Co-Ligne AG

发明人： Lange, Robert ,  Linge, Armand ,  Olson, Steve

IPC分类号： A61F2/44 ,  A61L27/44 ,  A61F2/30

CPC分类号： A61F2/4465 ,  A61F2/30965 ,  A61F2002/2835 ,  A61F2002/30009 ,  A61F2002/30434 ,  A61F2002/30438 ,  A61F2002/30462 ,  A61F2002/30604 ,  A61F2002/30777 ,  A61F2002/30784 ,  A61F2002/30971 ,  A61F2002/4485 ,  A61F2220/0041 ,  A61F2220/0075 ,  A61F2250/0028

摘要： The fusion implant apparatus comprises at least one biocompatible structure (12,13,14), wherein the structure is made of a composite material having reinforcing fibers (4,5). The structure has a first and second face (16,17) to engage adjacent bone structures (2,3) to be fused. Struts extend between said first and second faces. The structure includes a hollow interior space for reception of bone growth induding substances (8). The fibers are long fibers and wherein the majority of these long fibers (4) have a direction that follows the longitudinal forces upon said first and second faces, which is the direction of trabecular structures of the adjacent bone structure, so that said majority of long fibers (4) are essentially an extension of these trabecular structures.

摘要翻译： 该融合植入装置包括至少一个生物相容性结构（12,13,14），其中该结构由具有增强纤维（4,5）的复合材料制成。 该结构具有第一和第二面（16,17）以与相邻的骨结构（2,3）接合以被熔合。 支柱在所述第一和第二面之间延伸。 该结构包括用于接收骨生长诱导物质（8）的中空内部空间。 纤维是长纤维，并且其中这些长纤维（4）中的大多数具有跟随所述第一和第二面上的纵向力的方向，所述纵向力是相邻骨结构的小梁结构的方向，使得所述大部分长纤维 纤维（4）基本上是这些小梁结构的延伸。

公开(公告)号：EP0988001B1

公开(公告)日：2004-09-01

申请号：EP98929363.4

申请日：1998-05-22

申请人： Linvatec Biomaterials Oy

发明人： TORMALA, Pertti ,  PAASIMAA, Senja ,  LEHTO, Matti

IPC分类号： A61F2/30 ,  A61F2/42

CPC分类号： A61F2/4241 ,  A61B17/06166 ,  A61B17/68 ,  A61B17/86 ,  A61B2017/00004 ,  A61F2/0077 ,  A61F2/08 ,  A61F2/30721 ,  A61F2/30724 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/389 ,  A61F2/4225 ,  A61F2002/30009 ,  A61F2002/30011 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30064 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30293 ,  A61F2002/30324 ,  A61F2002/30448 ,  A61F2002/30461 ,  A61F2002/30462 ,  A61F2002/30466 ,  A61F2002/30537 ,  A61F2002/30545 ,  A61F2002/30593 ,  A61F2002/30673 ,  A61F2002/30677 ,  A61F2002/30685 ,  A61F2002/30777 ,  A61F2002/30785 ,  A61F2002/30841 ,  A61F2002/30914 ,  A61F2002/30934 ,  A61F2002/3096 ,  A61F2002/30975 ,  A61F2002/4228 ,  A61F2002/4233 ,  A61F2002/4243 ,  A61F2002/4251 ,  A61F2210/0004 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2230/0091 ,  A61F2250/0004 ,  A61F2250/001 ,  A61F2250/0023 ,  A61F2250/0028 ,  A61F2250/003 ,  A61F2250/0036 ,  A61F2310/00964 ,  A61F2310/00976

摘要： A cylindrical, fibrous, porous joint spacer is provided, having excellent properties, flexibility of formation, and operability, which is intended to be implanted as a prosthesis between bones (8, 9) to be joined together. The joint spacer can be formed from a strip of fabric (1), which is comprised of bioabsorbable fibers and made by a knitting, weaving, non-woven or other technique. The fabric (1) is typically relatively narrow (e.g. 1 to 10 mm wide) and thin (e.g. 0.1 to 1.0 mm thick), depending on the intended application of the prosthetic device to be formed from the fabric (1). The joint spacer is made by wrapping said fabric (1) to yield a cylindrical body (2); and fixing the free end of the fabric (1) to the surface of the cylindrical body (2) so formed. The joint spacer can be implanted in conjunction with one or more fixation parts (14', 14'), to hold the joint spacer in place between the bones (15, 16) to be joined.

摘要翻译： 提供圆柱形纤维状多孔接头隔离物，其具有优异的性能，形成的灵活性和可操作性，其打算作为假体植入待接合在一起的骨（8,9）之间。 该接头隔离物可以由一条织物（1）形成，该织物由生物可吸收纤维组成并且由编织，编织，无纺布或其他技术制成。 取决于由织物（1）形成的假体装置的预期应用，织物（1）通常相对较窄（例如1至10mm宽）和较薄（例如0.1至1.0mm厚）。 通过包裹所述织物（1）以形成圆柱形主体（2）来制造所述接头隔离物; 并将织物（1）的自由端固定到如此形成的圆柱形主体（2）的表面上。 该关节间隔件可以与一个或多个固定部件（14'，14'）一起植入，以将关节间隔件保持在要结合的骨骼（15,16）之间的适当位置。

公开(公告)号：EP1430857A1

公开(公告)日：2004-06-23

申请号：EP02406104.6

申请日：2002-12-17

申请人： Co-Ligne AG

发明人： Lange, Robert ,  Olson, Steven

IPC分类号： A61F2/44 ,  A61F2/30

CPC分类号： A61F2/30965 ,  A61F2/446 ,  A61F2/4465 ,  A61F2002/2835 ,  A61F2002/30009 ,  A61F2002/30383 ,  A61F2002/30604 ,  A61F2002/30787 ,  A61F2002/3085 ,  A61F2002/4475 ,  A61F2220/0025 ,  A61F2250/0028

摘要： The cylindrical fiber reinforced implant (1) is designed to be inserted between two adjacent vertebrae. The implant having an outer wall (2) with a general cylindrical or oval shape and preferably an open volume for bone filling. Said wall (2) having reinforcing fibers (12,17) which at least in part are oriented in a first direction. A support (6) extending within said volume having reinforcing fibers (10,11) which are at least in part oriented in a second direction, said first and said second directions are different. Preferably the fibers (12,17) of the outer wall (2) are at least partly concentrically oriented. The support (6) is preferably a separately formed part, that is inserted into the outer wall.

摘要翻译： 圆柱形纤维增强植入物（1）被设计成插入两个相邻的椎骨之间。 该植入物具有一般为圆柱形或椭圆形的外壁（2），优选用于骨填充的开口体积。 所述壁（2）具有至少部分地沿第一方向定向的增强纤维（12,17）。 在所述体积内延伸的支撑件（6）具有至少部分地沿第二方向定向的增强纤维（10,11），所述第一和所述第二方向是不同的。 优选地，外壁（2）的纤维（12,17）至少部分地同心取向。 支撑件（6）优选地是插入到外壁中的单独形成的部件。

公开(公告)号：EP0984745B1

公开(公告)日：2003-10-01

申请号：EP98934768.7

申请日：1998-05-22

申请人： Jansson, V. Dipl.-Ing. Dr. Med . ,  Zimmer, Markus, Dr.

发明人： Jansson, V. Dipl.-Ing. Dr. Med . ,  Zimmer, Markus, Dr.

IPC分类号： A61F2/28 ,  A61F2/30 ,  A61L27/00

CPC分类号： A61F2/30965 ,  A61F2/28 ,  A61F2/30749 ,  A61F2/30756 ,  A61F2/3872 ,  A61F2002/30004 ,  A61F2002/30009 ,  A61F2002/30011 ,  A61F2002/30062 ,  A61F2002/30131 ,  A61F2002/30199 ,  A61F2002/30224 ,  A61F2002/30261 ,  A61F2002/30322 ,  A61F2002/30329 ,  A61F2002/30462 ,  A61F2002/30785 ,  A61F2002/30789 ,  A61F2002/30915 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0013 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2250/0014 ,  A61F2250/0023 ,  A61F2250/0026 ,  A61F2250/0028 ,  A61F2310/00293 ,  A61F2310/00365 ,  A61F2310/00383 ,  A61L27/12 ,  A61L27/18 ,  A61L27/20 ,  A61L27/222 ,  A61L27/24 ,  A61L27/50 ,  A61L27/58 ,  C08L67/04 ,  C08L5/12

摘要： The invention relates to novel materials for replacement of bones or cartilages, characterized primarily by their unique structure comprising substances known per se. Since these structures can be produced by selecting the suitable physical and geometric parameters, it is possible to manufacture implants either to replace bone and cartilage or to manufacture cartilage bone composite implants which closely resemble the relevant natural bones or cartilages in terms of elasticity, porosity and solidity and which behave in a similar biological manner to the direct in vivo environment.