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    METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT
    37.
    发明公开
    METHOD FOR PREPARING SURFACE COATING WITH REDUCED DEGRADATION RATE OF BIODEGRADABLE MAGNESIUM ALLOY VASCULAR STENT 审中-公开
    VERFAHREN ZUR HERSTELLUNG EINEROBERFLÄCHENBESCHICHTUNGMIT REDUZIERTER ABBAUGESCHWINDIGKEIT EINESGEFÄSSSTENTSAUS EINER BIOLOGISCH ABBAUBAREN MAGNESIUMLEGIERUNG

    公开(公告)号：EP3144018A4

    公开(公告)日：2017-05-31

    申请号：EP15792801

    申请日：2015-04-30

    Applicant: JIANGSU FENGYUAN MEDICAL DEVICES CO LTD

    Inventor： LIU JING ,  WANG MIN ,  ZHANG ZHIXIONG ,  XI TINGFEL

    IPC: A61L31/10 ,  A61L31/02 ,  A61L31/08 ,  A61L31/14

    CPC classification number: A61L31/10 ,  A61L31/022 ,  A61L31/14 ,  A61L2420/02 ,  C08L67/04

    Abstract: Disclosed is a method for preparing a surface coating with a reduced degradation rate of a biodegradable magnesium alloy vascular stent, comprising firstly grafting a silane coupling agent to the surface of a magnesium ally by dip coating, heat curing, and forming a silane coupling agent coating on the surface of the magnesium alloy; and then coating a polymer on the surface of the silane coupling agent coating by spin coating, and drying under vacuum to form a polymer coating. The polymer coating on the surface of the magnesium alloy and pretreated by a silane coupling agent can enhance the bonding force with the surface of the magnesium alloy vascular stent to suppress excessive degradation of the magnesium alloy matrix, and improve the biocompatibility of the vascular stent.

    Abstract translation: 公开了一种制备生物降解性镁合金血管支架的降解速度降低的表面涂层的方法，该方法包括首先通过浸涂将硅烷偶联剂接枝到镁合金表面，加热固化并形成硅烷偶联剂涂层 在镁合金的表面上; 然后通过旋涂在硅烷偶联剂涂层的表面上涂覆聚合物，并在真空下干燥以形成聚合物涂层。 镁合金表面的聚合物涂层通过硅烷偶联剂预处理，可以增强与镁合金血管支架表面的结合力，抑制镁合金基体的过度降解，提高血管支架的生物相容性。

    BIODEGRADABLE WIRE WITH CENTRAL FILAMENT
    40.
    发明公开
    BIODEGRADABLE WIRE WITH CENTRAL FILAMENT 审中-公开
    生物学家ABBAUBARE DRAHT MIT ZENTRALEM FILAMENT

    公开(公告)号：EP3154480A1

    公开(公告)日：2017-04-19

    申请号：EP15806272.9

    申请日：2015-06-12

    Applicant: Fort Wayne Metals Research Products Corporation

    Inventor： SCHAFFER, Jeremy, E. ,  GRIEBEL, Adam, J.

    IPC: A61F2/82 ,  A61L31/00 ,  B23P11/00

    CPC classification number: A61L31/10 ,  A61B17/06166 ,  A61B17/064 ,  A61B2017/00004 ,  A61F2/01 ,  A61F2/86 ,  A61F2002/016 ,  A61F2210/0004 ,  A61F2250/003 ,  A61L17/12 ,  A61L31/022 ,  A61L31/148 ,  C08L67/04

    Abstract: A composite wire product includes a biodegradable parent material which forms the bulk of the cross-sectional area of the wire, and a central fiber or filament of a slower-degrading or non-biodegradable material runs throughout the length of the wire. This central filament promotes the mechanical integrity of an intraluminal appliance or other medical device made from the wire product throughout the biodegradation process by preventing non-absorbed parent material from dislodging from the central filament. Thus, the present wire design enables the creation of medical devices that are designed to improve in flexibility toward a more natural state over the course of healing, while also controlling for the possibility of non-uniform in vivo erosion.

    Abstract translation: 复合丝产品包括形成线的横截面面积的大部分的生物可降解母体材料，并且较低分解或不可生物降解的材料的中心纤维或长丝贯穿丝线的整个长度。 该中心细丝通过防止未吸收的母体材料从中心细丝移出而促进整个生物降解过程中由丝产品制成的管腔内器具或其它医疗器械的机械完整性。 因此，本发明的线材设计使得能够创建医疗装置，其被设计成在愈合过程中朝向更自然状态提高灵活性，同时还控制体内不均匀侵蚀的可能性。

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