公开(公告)号：EP1775592A4

公开(公告)日：2012-05-09

申请号：EP05765718

申请日：2005-07-12

Applicant: ARKRAY INC

Inventor： FUJIMOTO KOJI ,  HORI MASAKI

IPC: G01N35/08 ,  G01N1/00 ,  G01N1/10 ,  G01N31/20 ,  G01N33/52 ,  G01N37/00

CPC classification number: G01N35/00069 ,  G01N2035/00267 ,  G01N2035/0441 ,  G01N2035/0491

公开(公告)号：EP1637872A4

公开(公告)日：2012-01-18

申请号：EP04736587

申请日：2004-06-10

Applicant: SONY CORP

Inventor： MAMINE TAKAYOSHI ,  SAKAMOTO YASUHIRO ,  FURUKI MOTOHIRO ,  NAKAO ISAMU

IPC: G01N21/64 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/68 ,  G01N21/25 ,  G01N33/53 ,  G01N33/536 ,  G01N33/58 ,  G01N35/00 ,  G01N37/00

CPC classification number: G01N21/6452 ,  G01N21/6428 ,  G01N33/582 ,  G01N35/00069 ,  G01N2021/6482

公开(公告)号：EP1896180B1

公开(公告)日：2011-11-23

申请号：EP06765771.8

申请日：2006-06-16

Applicant: Biocartis SA

Inventor： VAN HAAG, Chris ,  JONGERIUS, Michiel, J. ,  SCHAEFER, Danny, G., A. ,  VAN DEN BIJGAART, Adrianus, W., D., M. ,  DE GIER, Ronald, C. ,  DE JONG, Michiel ,  PROSS, Gerhard ,  BACHER, Johannes ,  BOOS, Andreas ,  LUEDKE, Gerd ,  SEHER, Jens-Peter

IPC: B01L3/00 ,  G01N1/28 ,  G01N21/76 ,  G01N35/00 ,  G01N33/487

CPC classification number: B01L7/52 ,  B01L3/502715 ,  B01L3/502738 ,  B01L3/545 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/10 ,  B01L2300/02 ,  B01L2300/087 ,  B01L2300/1805 ,  G01N21/6428 ,  G01N35/00069 ,  G01N2035/00158

Abstract: Disclosed is a cartridge for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. The cartridge comprises a generic part and one or more separate application-specific parts, which are connectable to the generic part. Also disclosed is a system for the detection of the presence, absence and/or amount of a target nucleotide sequence in a sample comprising one or more nucleic acid sequences. This system comprising a reusable apparatus, wherein said apparatus is configured to receive a cartridge and to control a process for the detection of the presence, absence and/or amount of a target nucleotide sequence in the sample, being present in said cartridge.

公开(公告)号：EP2375256A1

公开(公告)日：2011-10-12

申请号：EP11173036.2

申请日：2008-07-23

Applicant: Samsung Electronics Co., Ltd.

Inventor： Lee, Jungnam ,  Lee, Jeonggun ,  Park, Jongmyeon ,  Cho, Yoonkyoung

IPC: G01N35/00 ,  C12M1/02 ,  C12M1/10 ,  C12M1/42 ,  B01L3/00 ,  G01N33/483 ,  G01N33/53 ,  G01N33/543 ,  G01N27/447 ,  F16K99/00 ,  B01F15/02 ,  B01F13/00 ,  B01F11/00

CPC classification number: B01F11/0002 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/502761 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/0609 ,  B01L2300/0806 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2300/18 ,  B01L2300/1861 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N35/00069

Abstract: Provided are a centrifugal force-based microfluidic device for separating and amplifying a nucleic acid of a target cell and a microfluidic system including the same. The microfluidic device includes a rotary platform; a target cell nucleic acid extraction unit; and a polymerase chain reaction (PCR) unit wherein in a microfluidic structure arranged in the platform and connected to the target cell nucleic acid extraction unit.

Abstract translation: 提供了用于分离和扩增靶细胞的核酸的离心力微流体装置和包括其的微流体系统。 微流体装置包括旋转平台; 靶细胞核酸提取单元; 和聚合酶链式反应（PCR）单元，其中在布置在平台中并连接到靶细胞核酸提取单元的微流体结构中。

公开(公告)号：EP2281633A8

公开(公告)日：2011-06-29

申请号：EP10183978.5

申请日：2002-08-28

Applicant: GYROS PATENT AB

Inventor： Andersson, Per ,  Ekstrand, Gunnar

IPC: B01L3/00

CPC classification number: B01F5/0646 ,  B01F5/0647 ,  B01F5/0655 ,  B01F13/0059 ,  B01F15/0201 ,  B01F15/0233 ,  B01J2219/00536 ,  B01J2219/00725 ,  B01J2219/00738 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/502738 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/142 ,  B01L2300/0806 ,  B01L2300/087 ,  B01L2300/16 ,  B01L2400/0409 ,  B01L2400/0418 ,  B01L2400/0633 ,  B01L2400/0688 ,  C40B40/10 ,  G01N30/466 ,  G01N30/6095 ,  G01N35/00069

Abstract: A microfluidic device having a microchannel structure in which there are one or more inlet ports, one or more outlet ports, and a structural unit in communication with at least one of said ports, wherein the structural unit is a mixing unit that enables mixing of aliquots of liquid that are miscible with each other, and which said mixing unit comprises:
a microcavity (203) with an outlet opening (223); an inlet arrangement (201) linked to the microcavity, and a mixing microconduit (202) connected to the outlet opening, wherein said microcavity has a volume sufficient to contain simultaneously the aliquots to be mixed.

公开(公告)号：EP2329276A2

公开(公告)日：2011-06-08

申请号：EP09817962.5

申请日：2009-09-24

Applicant: Samsung Electronics Co., Ltd.

Inventor： LEE, Beom Seok ,  KIM, Ji Won ,  LEE, Jeong Gun ,  KIM, Kui Hyun

IPC: G01N35/00

CPC classification number: B01L3/50273 ,  B01L3/502738 ,  B01L3/545 ,  B01L2200/0621 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2300/021 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N21/07 ,  G01N33/54386 ,  G01N35/00069

Abstract: Provided is a microfluidic apparatus including: a microfluidic structure for providing spaces for receiving a fluid and for forming channels, through which the fluid flows; and valves for controlling the flow of fluid through the channels in the microfluidic apparatus. The microfluidic structure includes: a sample chamber; a sample separation unit receiving the sample from the sample chamber and separating a supernatant from the sample by using a centrifugal force; a testing unit receiving the supernatant from the sample separation unit for detecting a specimen from the supernatant using an antigen-antibody reaction, and a quality control chamber for identifying reliability of the test.

公开(公告)号：EP2175278A4

公开(公告)日：2011-05-18

申请号：EP08776882

申请日：2008-07-25

Applicant: PANASONIC CORP

Inventor： HIROSHI SAIKI

IPC: G01N35/00 ,  B01J19/00 ,  G01N33/48 ,  G01N35/08 ,  G01N37/00

CPC classification number: B01L3/502 ,  B01L2200/10 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2400/0409 ,  G01N33/726 ,  G01N35/00069 ,  G01N35/08 ,  G01N2035/00495 ,  Y10T436/111666 ,  Y10T436/25625 ,  Y10T436/2575

Abstract: A device for analysis used for transferring a solution to a measurement spot 38 by a centrifugal force and reading in which a reaction liquid located at the measurement spot 38 is optically accessed. An operation cavity 30 and a receiving cavity 32 are arranged from the upstream side to the downstream side of the transfer. The operation cavity 30 and the receiving cavity 32 communicate with each other via a connection section 59 to transfer the solution of the operation cavity 30 to the receiving cavity 32. The connection section 59 is located inside the liquid level of a diluted solution retained in the operation cavity 30, relative to a rotation axis 102.

公开(公告)号：EP2309266A1

公开(公告)日：2011-04-13

申请号：EP09170833.9

申请日：2009-09-21

Applicant: F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

Inventor： Oosterbroek, Edwin ,  Niederberger, Brigitte

IPC: G01N33/543 ,  B01L3/00 ,  G01N35/00 ,  B04B5/04

CPC classification number: G01N33/54366 ,  B01L3/502753 ,  B01L2200/0631 ,  B01L2300/0806 ,  B01L2300/087 ,  B01L2300/0887 ,  B01L2400/0409 ,  G01N35/00069

Abstract: Method and system for carrying out heterogeneous chemical or biological reactions, the method comprising the steps of providing an analytical device comprising at least one liquid processing unit, the liquid processing unit comprising at least one reaction chamber, and at least a first inlet channel in fluid communication with the reaction chamber, supplying to the reaction chamber via the first inlet channel or a second inlet channel analyte capturing particles, supplying to the reaction chamber via the first inlet channel or the second inlet channel a liquid sample containing at least an analyte of interest, confining by an equilibrium of forces the analyte capturing particles in a particle rearrangement zone comprised in the reaction chamber, said forces comprising a drag force Fd generated by liquids flowing through the first inlet channel and a counter-oriented force Fg, capturing analytcs present in the liquid sample with the particles in the particle rearrangement zone.

Abstract translation: 用于进行异质化学或生物反应的方法和系统，所述方法包括以下步骤：提供包括至少一个液体处理单元的分析装置，所述液体处理单元包括至少一个反应室，以及至少一个流体中的第一入口通道 与反应室的连通，经由第一入口通道或第二入口通道分析物捕获颗粒供应到反应室，经由第一入口通道或第二入口通道向反应室供应至少含有感兴趣分析物的液体样品 通过在分析物捕获颗粒在包含在反应室中的颗粒重排区域中的力平衡来限制，所述力包括由流过第一入口通道的液体产生的牵引力Fd和反向取向力Fg，捕获分析物存在于 液体样品中的颗粒在颗粒重排区域。

公开(公告)号：EP2295985A1

公开(公告)日：2011-03-16

申请号：EP09794444.1

申请日：2009-07-07

Applicant: Sanko Junyaku Co., Ltd. ,  Eisai R&D Management Co., Ltd.

Inventor： KAWAMURA, Toshimi ,  ISHIOKA, Seiichirou ,  TONARI, Masaki ,  KAWAMURA, Takashi ,  NAKAJIMA, Akira ,  SEKINO, Tetsuo ,  IWAHASHI, Kyoichi ,  UCHIYAMA, Kenichi ,  TAKASE, Tomohiro ,  NAWATA, Isao

IPC: G01N35/00 ,  G01N37/00

CPC classification number: G01N33/491 ,  B01L3/5027 ,  B01L2200/16 ,  B01L2300/0803 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N35/00069

Abstract: A clinical examination disk according to the invention includes a disk body in a disk form, and at least one cell formed in the disk body, wherein the cell comprises a specimen reservoir formed in the disk body and having a specimen injecting port, a reaction tank formed in the disk body so as to position nearer to the outer circumference of the body than a position of the specimen reservoir, and holding a reagent which is reactive with the specimen and is beforehand gelatinized, a first narrow tube formed in the disk body, and communicating to the specimen reservoir and the reaction tank, and a second narrow tube formed in the disk body, and having one end connected to the reaction tank and the other end made open.

Abstract translation: 临床检查用圆盘雅丁到本发明包括一个圆盘状的盘体，并且在所述圆盘主体中形成的至少一个小区，worin所述细胞包含在盘体形成的检体贮存室，并具有一个样品注射端口，反应槽 形成在盘体，从而更接近地定位于所述主体的外圆周比检体贮存室的位置，并且保持一个试剂所有这些是与试样的反应性和预先凝胶化，第一细管在盘体构成， 并传送到所述检体贮存室与所述反应槽，以及第二细管在盘体形成，并且其一端连接到所述反应槽上，另一端成为开路。

公开(公告)号：EP1714699B1

公开(公告)日：2010-08-18

申请号：EP06075151.8

申请日：1999-01-05

Applicant: Massachusetts Institute of Technology

Inventor： Hunter, Ian W.

IPC: B01L3/00

CPC classification number: B01J19/0046 ,  B01F13/0071 ,  B01F13/0084 ,  B01J2219/00313 ,  B01J2219/00317 ,  B01J2219/00351 ,  B01J2219/00533 ,  B01J2219/00536 ,  B01J2219/00549 ,  B01J2219/00585 ,  B01J2219/00599 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50857 ,  B01L2200/0642 ,  C12Q1/34 ,  C40B60/14 ,  C40B70/00 ,  G01N21/75 ,  G01N35/00069 ,  G01N35/1002 ,  G01N2035/00237 ,  Y10T436/11 ,  Y10T436/112499 ,  Y10T436/25