Method of producing polyisoprenoid compounds by carbon-carbon bond formation
    38.
    发明公开
    Method of producing polyisoprenoid compounds by carbon-carbon bond formation 失效
    一种用于通过形成碳 - 碳键制备Polyisoprenoideverbindungen过程。

    公开(公告)号:EP0001873A1

    公开(公告)日:1979-05-16

    申请号:EP78300205.8

    申请日:1978-07-26

    IPC分类号: C07C11/21 C07C33/02 C07C49/73

    摘要: A polyisoprenoid compound is prepared by reacting a compound R CH 2 Y wherein Y is lower alkylsulfonyl or arylsulfonyl, and R 1 is isoprenoid or polyisoprenoid, with a XCH 2 R 2 compound wherein X is halogen and R 2 has the same meaning as R', in a polar solvent and in the presence of sodium hydride, potassium hydride, sodium tertiary-alkoxide, potassium tertiary-alkoxide, sodium amide or potassium amide, to obtain a compound
    which, in turn, is subjected to a reductive desulfonylation of the group Y, whereby a compound R 1 CH 2 CH 2 R 2 is obtained.

    摘要翻译: 聚类异戊二烯化合物是通过使一化合物R制备<1> CH2Y worin Y是低级烷基磺酰基或芳基磺酰基,并且R <1>是类异戊二烯或聚类异戊二烯,具有XCH2R <2>化合物worin X是卤素,R <2>具有 相同的含义为R <1>,在极性溶剂中,在氢化钠,氢化钾,钠叔醇盐,钾醇盐叔胺,氨基钠或氨基钾的存在下,得到的化合物,这反过来 ,进行与基团Y的还原脱磺酰,由此化合物R <1> CH 2 CH 2 <2>中获得。