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148 条记录 (耗时 0.014 秒)

    Fibrous collagenous hemostatic-adhesive web and method for its preparation
    51.
    发明公开
    Fibrous collagenous hemostatic-adhesive web and method for its preparation 失效
    止血，由胶原制成的粘合剂的非织造织物，以及其制备方法。

    公开(公告)号：EP0042253A1

    公开(公告)日：1981-12-23

    申请号：EP81302581.4

    申请日：1981-06-10

    申请人： ALCON (PUERTO RICO) INC.

    发明人： Serravallo, Fred Albert

    IPC分类号： A61L15/04 ,  D21H5/12

    CPC分类号： D21H13/34 ,  A61L15/325 ,  A61L24/102 ,  A61L26/0033 ,  A61L2400/04 ,  D21H5/1209

    摘要： A fibrous, velvet-like, non-woven web having hemostatic and adhesive properties adapted to seal a wound comprising fibers of collagen or an ionizable, water-insoluble, partial salt of collagen. The web is formed by slurrying the fibers, which have hemostatic and adhesive properties, in an aqueous liquid, introducing a predetermined amount of slurry into a tray and freeze drying the slurry.

    摘要翻译： 纤维状，丝绒状，无纺布具有止血和粘合性能幅angepasst以密封伤口，其包括胶原蛋白或胶原蛋白的可离子化的，水不溶性，部分盐的纤维。 该网由浆纤维，其具有止血和粘接性能，在液体wässrige，引入淤浆的预定量到托盘并冷冻干燥该浆料而形成。

    HEMOSTATIC COMPOSITIONS
    58.
    发明公开
    HEMOSTATIC COMPOSITIONS 审中-公开
    静脉内组合物

    公开(公告)号：EP2701729A1

    公开(公告)日：2014-03-05

    申请号：EP12717682.4

    申请日：2012-04-26

    申请人： BIOM'UP

    发明人： GAGNIEU, Christian ,  FOREST, Patricia ,  PICOT, Sylvain

    IPC分类号： A61K38/36 ,  A61K38/39 ,  A61P7/04

    CPC分类号： A61K38/4833 ,  A61K9/14 ,  A61K31/726 ,  A61K38/36 ,  A61K38/39 ,  A61K47/26 ,  A61L26/0033 ,  A61L2400/04 ,  C12Y304/21005

    摘要： The invention relates to a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device.

    摘要翻译： 本发明涉及粉末形式的止血组合物，所述组合物包含纤维状类型的胶原，其包含纤维胶原和/或原纤维胶原含量相对于胶原蛋白总重量的至少70重量％，和至少一种单糖，以及 任选地，至少一种选自凝结因子和葡糖胺聚糖的化合物。 本发明还涉及制备这种组合物的方法，以及包含这种组合物的单元和喷雾装置。

    METHODS FOR TREATING BACTERIAL INFECTION
    59.
    发明公开
    METHODS FOR TREATING BACTERIAL INFECTION 审中-公开
    VERFAHREN ZUR BEHANDLUNG VON BAKTERIENINFEKTIONEN

    公开(公告)号：EP2696875A1

    公开(公告)日：2014-02-19

    申请号：EP12711420.5

    申请日：2012-04-02

    申请人： Innocoll Technologies Limited

    发明人： PRIOR, David

    IPC分类号： A61K31/5383 ,  A61K31/7036 ,  A61K45/06 ,  A61K38/39 ,  A61P17/02 ,  A61P31/02 ,  A61P31/04 ,  A61L26/00 ,  A61K9/00

    CPC分类号： A61K31/7036 ,  A61K31/5383 ,  A61K38/39 ,  A61K45/06 ,  A61L26/0033 ,  A61L26/0066 ,  A61L27/24 ,  A61L27/54 ,  A61L2300/406 ,  A61K2300/00

    摘要： This invention relates to methods for treating bacterial infection, which methods find utility in the treatment of, for example, infected ulcers, optionally infected diabetic ulcers. In particular, this invention relates to treating bacterial infection, for example, infected diabetic ulcers by topical administration of at least one aminoglycoside antibiotic at the site of infection, in combination with at least one antibacterial agent, which antibacterial agent is administered remote from the site of infection, preferably administered systemically. In a particular embodiment, the present invention relates to a composition for use in treating bacterial infection, the composition comprising gentamicin sulphate (a water-soluble broad-spectrum aminoglycoside antibiotic) uniformly dispersed in a type-I collagen matrix; incombination with at least one systemically-administered antibacterial agent. The present invention provides bactericidal activity against most strains of aerobic gram-negative and gram-positive and facultative anaerobic gram-negative pathogens, including methicillin-resistant
    Staphylococcus aureus .

    摘要翻译： 本发明涉及治疗细菌感染的方法，该方法可用于治疗例如感染性溃疡，任选感染的糖尿病性溃疡。 特别地，本发明涉及通过在感染部位局部施用至少一种氨基糖苷类抗生素与至少一种抗菌剂组合治疗细菌感染，例如感染的糖尿病性溃疡，该抗菌剂远离该部位 的感染，优选全身性给药。 在一个具体实施方案中，本发明涉及用于治疗细菌感染的组合物，所述组合物包含均匀分散在I型胶原基质中的硫酸庆大霉素（水溶性广谱氨基糖苷类抗生素）; 与至少一种全身施用的抗菌剂组合。 本发明对大部分需氧革兰氏阴性和革兰氏阳性和兼性厌氧革兰氏阴性病原体菌株提供杀菌活性，包括耐甲氧西林金黄色葡萄球菌。