公开(公告)号：EP2321631A1

公开(公告)日：2011-05-18

申请号：EP09805355.6

申请日：2009-07-24

Applicant: Invensys Systems, Inc.

Inventor： TRYGSTAD, W., Marcus

IPC: G01N25/00

CPC classification number: G01N21/359 ,  G01N21/3577 ,  G01N24/08 ,  G01N24/081 ,  G01N24/085 ,  G01N2021/8416 ,  G01N2201/1211 ,  G01R33/44 ,  Y10T436/166666 ,  Y10T436/216 ,  Y10T436/218

Abstract: A method and apparatus is provided for concentration determination of at least one component in an acid catalyst for hydrocarbon conversion containing an unknown concentration of an acid, an acid-soluble-oil (ASO), and water. An instrument configured for measuring a property of the acid catalyst, has responsivities to concentrations of one of the acid, ASO, and water, substantially independent of the concentrations of the others of the acid catalyst, ASO, and water. A temperature detector is configured to generate temperature data for the acid catalyst. A processor is configured to capture data generated by the temperature detector and the instrument, and to use the data in combination with a model to determine a temperature compensated concentration of the one of the acid, the ASO, and the water. Optionally, one or more other instruments configured for measuring other properties of the liquid mixture may also be used.

公开(公告)号：EP2306233A2

公开(公告)日：2011-04-06

申请号：EP10075604.8

申请日：2005-11-03

Applicant: Life Technologies Corporation

Inventor： Oldham, Mark F. ,  Mirchandani, Vinod L. ,  Hoshizaki, Jon A. ,  King, Howard G. ,  Sluis, Johannes P. ,  Boege, Steven J.

IPC: G02B26/10 ,  G01N21/64 ,  G05D23/00 ,  G01N33/53 ,  H05B33/08

CPC classification number: G01N21/64 ,  F21K9/00 ,  F21K9/64 ,  F21V29/54 ,  F21V29/677 ,  F21V29/74 ,  F21Y2115/10 ,  G01J3/0286 ,  G01J3/10 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/0638 ,  G01N2201/1211 ,  G05D23/1919 ,  G05D23/20

Abstract: The present invention relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures. According to various embodiments, a system is provided that includes one or more LED (111), a temperature sensor (118), and a temperature regulator (122). The temperature sensor can be in thermal contact with the LED (111), can be capable of measuring an operating temperature, and can be capable of generating an operating temperature signal. The temperature regulator can be capable of receiving an operating temperature signal of the LED and regulating the operating temperature based on the operating temperature signal. According to various embodiments, a method for illuminating a reaction region (108) with excitation beams is provided. The method can include providing a system (100) that includes an LED (111) and a reaction region (108). The method can include generating excitation beams with LED; directing the excitation beams toward the reaction region measuring an operating temperature of the LED; and regulating the operating temperature by transferring heat away from and/or into the LED, based on the measured operating temperature. The reaction region includes a sample.

Abstract translation: 本发明涉及用于进行样品测定以及用于产生和测量光学响应和标记的方法和系统。 根据各种实施例，提供了一种系统，其包括一个或多个LED（111），温度传感器（118）和温度调节器（122）。 温度传感器可以与LED（111）热接触，能够测量工作温度，并且能够产生工作温度信号。 温度调节器能够接收LED的工作温度信号并且基于工作温度信号来调节工作温度。 根据各种实施例，提供了一种用激发光束照射反应区域（108）的方法。 该方法可以包括提供包括LED（111）和反应区域（108）的系统（100）。 该方法可以包括用LED产生激发光束; 将激发光束引向测量LED的工作温度的反应区域; 以及基于所测量的操作温度通过将热量从LED和/或LED传递出来来调节操作温度。 反应区域包括样品。

公开(公告)号：EP2010890A2

公开(公告)日：2009-01-07

申请号：EP07702562.5

申请日：2007-01-02

Applicant: Opsolution Spectroscopic Systems GmbH ,  Biozoom Services GmbH

Inventor： WILLEMER, Winfried ,  KRIEG, Jürgen ,  SANDHAGEN, Carl

IPC: G01N21/35 ,  G01N21/27 ,  G01J3/42

CPC classification number: G01N21/274 ,  G01N21/359 ,  G01N2021/3144 ,  G01N2021/3181 ,  G01N2201/1211

Abstract: The invention relates to a method and a device for producing a test result indicative of the presence or concentration of a substance in a sample. The aim of the invention is to create solutions which allow the concentration of a substance to be determined reliably by a spectrometer while the respective measurement can be taken within a relatively short period of time without including a reference measurement in a direct temporal proximity of the measurement and without going through a preliminary operating phase to stabilize the device. According to a first embodiment of the invention, said aim is achieved by a method for producing a test result indicative of the presence of a substance in a sample based on a spectrometric measurement. In said method, light is emitted to said sample from a source during an illumination phase, light marked by the interaction with said sample is detected in terms of the spectral intensity distribution, and the concentration of a substance or a variable related to the concentration is determined during a computer-aided mathematical test signal processing process taking into account the spectral intensity distribution of the detected light, an LED being used as a light source. A compensation function which takes into account dependencies of the spectral intensity distribution of the light emitted by the light source on the temperature of the LED is processed during the computer-aided mathematical test signal processing process, thus advantageously making it possible to take a spectrometric measurement without going through a time-consuming heating phase of the measurement system. The measurement can be taken immediately using the device at ambient temperature.

公开(公告)号：EP2010875A1

公开(公告)日：2009-01-07

申请号：EP07724382.2

申请日：2007-04-19

Applicant: Opsolution Spectroscopic Systems GmbH

Inventor： WILLEMER, Winfried ,  KRIEG, Jürgen ,  SANDHAGEN, Carl

IPC: G01J3/28 ,  G01N21/27 ,  A61B5/00

CPC classification number: G01N21/274 ,  G01J3/28 ,  G01J3/501 ,  G01N2201/062 ,  G01N2201/1211

Abstract: The invention relates to a method and to an electronic circuit for processing signals which as such are indicative of the features or characteristics of the spectral distribution of light which is supplied for spectrometric measurements combined with an LED light source. The problem of the invention is to provide solutions which allow the informative value of spectrometric measurements to be increased. For this purpose, a reference curve for the spectral emission is calculated based on a reference measurement and at least two additional measurements on the same reference, said spectral emission being used as a reference when carrying out measurements of practically any objects. This curve is determined in such a manner that it corresponds to a curve of the spectral emission at a temperature that is outside or far outside the temperature range of the actual temperatures of the LED during the measurements.

公开(公告)号：EP2000801A2

公开(公告)日：2008-12-10

申请号：EP07739617.4

申请日：2007-03-26

Applicant: Terumo Kabushiki Kaisha

Inventor： SUGAWARA, Yoshihisa

IPC: G01N33/52 ,  G01N21/78

CPC classification number: G01N21/8483 ,  G01J1/32 ,  G01J3/10 ,  G01N21/255 ,  G01N21/274 ,  G01N21/4738 ,  G01N33/52 ,  G01N2201/0695 ,  G01N2201/1211

Abstract: A body fluid constituents measurement device, which performs measurement under a setting where light intensity of the light-emitting element is suitably stabilized, is provided. The present invention is a body fluid constituents measurement device which comprises: a light-emitting element that emits light onto a test paper onto which body fluid is spotted, a light receiving element which receives reflected light of the light emitted by said light-emitting element, a temperature measurement unit which measures the ambient temperature in the vicinity of said light-emitting element, a determination unit which determines conditions of light emission based on said temperature measured at said temperature measurement unit in order to stabilize light intensity of said light-emitting element, and a driving control unit which controls driving of said light-emitting element based on the conditions of light emission; and is characterized in that it starts measurement of body fluid constituents after the light intensity of light emitted by said light-emitting element has been stabilized.

Abstract translation: 本发明提供一种体液成分测量装置，其在发光元件的光强度适当稳定的设定下进行测量。 本发明是一种体液成分测量装置，其特征在于，包括：发光元件，其将光发射到被测定了体液的试纸上;光接收元件，其接收由所述发光元件发射的光的反射光 ，测量所述发光元件附近的环境温度的温度测量单元，确定单元，其基于在所述温度测量单元测量的所述温度来确定发光条件，以便稳定所述发光元件的光强度 元件和驱动控制单元，其基于发光条件来控制所述发光元件的驱动; 并且其特征在于，在由所述发光元件发出的光的光强已经稳定之后开始测量体液成分。

公开(公告)号：EP1807726A2

公开(公告)日：2007-07-18

申请号：EP05849156.4

申请日：2005-11-03

Applicant: Applera Corporation

Inventor： OLDHAM, Mark, F. ,  MIRCHANDANI, Vinod, L. ,  HOSHIZAKI, Jon, A. ,  KING, Howard, G. ,  SLUIS, Johannes, P. ,  BOEGE, Steven, J.

IPC: G02B26/10 ,  G01N21/64 ,  G05D23/00 ,  F21K7/00 ,  G01N33/53 ,  H05B33/08

CPC classification number: G01N21/64 ,  F21K9/00 ,  F21K9/64 ,  F21V29/54 ,  F21V29/677 ,  F21V29/74 ,  F21Y2115/10 ,  G01J3/0286 ,  G01J3/10 ,  G01N21/645 ,  G01N21/6452 ,  G01N2021/6439 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/0638 ,  G01N2201/1211 ,  G05D23/1919 ,  G05D23/20

Abstract: Methods and optical systems for thermally compensated optical scanning of a target sample. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.

公开(公告)号：EP1805516A1

公开(公告)日：2007-07-11

申请号：EP05815308.1

申请日：2005-10-14

Applicant: Becton, Dickinson & Company

Inventor： KEITH, Steven ,  PALMER, Phyllis, J.

IPC: G01N33/542 ,  G01N33/543 ,  A61B5/00 ,  G01N33/66

CPC classification number: G01N21/7703 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/1495 ,  A61B2560/0223 ,  A61B2560/0252 ,  G01N21/274 ,  G01N21/6428 ,  G01N33/542 ,  G01N33/54373 ,  G01N2021/7786 ,  G01N2201/1211

Abstract: The invention is directed to methods of correcting a luminescence value, and methods of determining a corrected analyte concentration, by use of a device capable of providing a signal when a binding protein binds to at least one analyte, and a thermometer. The invention is also directed to systems which include such a device, and a processor for correcting measured luminescence of a reporter group based on a measured temperature. The invention is further directed to apparatuses that include a memory for storing luminescence information and temperature information, and a processor for correcting luminescence information. The invention is further directed to computer programs for executing the methods of the invention, and machine-readable storage medium on which programs are recorded.

公开(公告)号：EP1664743A1

公开(公告)日：2006-06-07

申请号：EP04749195.6

申请日：2004-08-10

Applicant: Senseair AB

Inventor： MARTIN, Hans, Göran, Evald

IPC: G01N21/27 ,  G01N33/00 ,  G01N37/00

CPC classification number: G01D3/0365 ,  G01D3/036 ,  G01N21/274 ,  G01N21/3504 ,  G01N33/0006 ,  G01N2201/1211

Abstract: The present invention relates to a method and to an electronic arrangement (6) for causing a temperature depending error compensation to measured values, said compensation is related, among other things, to a 'drift' error source, in respect of measuring processes which utilise a sensor (1). Electronic circuits (6) are adapted to establish the presence of one or more gases and/or gas mixtures and/or to calculate the concentration of such a gas or gas mixtures. A highest measurement value (Mmax) or a lowest measurement value (Mmin) occurring and established during a chosen measuring cycle (T1) shall be stored in a memory (69´). It is particularly proposed; that a lowest analogue value or a highest digitalised measurement value occurring and evaluated during a chosen time period (T1) shall be stored in said memory (69´); that the occurring and evaluated measurement value (Mmax; Mmin) at the end of a chosen measuring cycle or time period (T1) shall be compared with a stored analogue or through an A/D-converter digitalised control value (65´); and that a discrepancy between the evaluated measured lowest or highest values and said stored control value is used as the basis for related and/or corresponding compensation (K1) of the measurement values occurring in a following time period (T2).

公开(公告)号：EP1576357A1

公开(公告)日：2005-09-21

申请号：EP03813936.6

申请日：2003-12-23

Applicant: Imstar Image et Modelisation: Strategie, Analyse et Realisation

Inventor： SOUSSALINE, Françoise ,  KHOMYAKOVA, Elena

IPC: G01N21/64

CPC classification number: G01N21/6452 ,  G01N2021/6482 ,  G01N2201/1211

Abstract: The invention relates to a device which is used to read and analyse chips. The inventive device comprises a table (11) for receiving a chip (12) that is intended to characterise at least one sample, means of exciting the molecules or cells of the chip after reaction with other molecules and means (14) of reading and analysing the molecules subjected to excitation. The invention is characterised in that the device also comprises: a unit (15) for controlling the temperature of the aforementioned table, said control unit being connected to a module (111) consisting of a plurality of Peltier-type heating/cooling elements which are disposed opposite different slots on the surface of the table; and at least one table temperature sensor (112) which is also connected to said control unit. The invention also relates to the associated methods.

公开(公告)号：EP0353590B1

公开(公告)日：1996-04-17

申请号：EP89113615.2

申请日：1989-07-24

Applicant: ABBOTT LABORATORIES

Inventor： Durley, Benton Alvin, III ,  Merkh, Carl Walter ,  Defreese, James Douglas

IPC: G01N35/02 ,  G01N33/53 ,  B01L3/00

CPC classification number: G01N35/00029 ,  B01L3/545 ,  G01N33/54366 ,  G01N33/6854 ,  G01N2021/478 ,  G01N2035/00099 ,  G01N2035/00752 ,  G01N2035/1025 ,  G01N2201/0415 ,  G01N2201/0621 ,  G01N2201/1211 ,  Y10S435/805