摘要:
The present invention relates to (R,S) 2-aryl-2-fluoropropanoic acids, their single enantiomers (R) and (S), their derivatives amides and acylsulfonamides and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacerbated recruitment of polymorphonucleated neutrophils (PMN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the treatment of damages caused by ischemia and reperfusion.
摘要:
Combined pharmaceutical preparation containing G-CSF and PIGF as the active substances, are useful in the mobilization of blood stem cells in a patient or subject in need thereof.
摘要:
A container for liquid or pasty substances or powders, suspensions or liposomial preparations, for pharmaceuticals, diagnostics, cosmetics or similar, enclosed in a plate 6 of plastic material, comprising two semi-containers 2 with bodies 4 and necks 3, close together and parallel. Pre-cut lines 9-10; 109-110 are provided and at least some of these concern the topi of the said necks 3, in such a way as making a separation along these pre-cut lines causes the selective opening of a said semi-container 2, or of both of them, and therefore the dispensing of a half dose or of the entire dose of the product in the container 1. A set 20 of containers 1 is also described, comprising a plurality of containers 1 joined between themselves along lines of breakable joints 21 and that allow their separation at the moment of use.
摘要:
The compounds of formula (1), wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.
摘要:
The present invention refers to the use of Macrophage Stimulating Protein (MSP) for the preparation of a medicament for the treatment of pathologies of the central and peripheral nervous system of traumatic, infectious or inflammatory origin.
摘要:
The present invention refers to the use of Macrophage Stimulating Protein (MSP) for the preparation of a medicament for the treatment of pathologies of the central and peripheral nervous system of traumatic, infectious or inflammatory origin.
摘要:
The invention relates to compounds acting as selective antagonists of Transient Receptor Potential cation channel subfamily M member 8 (TRPM8), and having formula:
Said compounds are useful in the treatment of diseases associated with activity of TRPM8 such as pain, inflammation, ischaemia, neurodegeneration, stroke, psychiatric disorders, inflammatory conditions and urological disorders.
摘要:
A method for the preparation of molecular weight standards having peroxidase activity which can be directly identified at the time of the detection of the antigen in all western blot techniques based on the use of peroxidase.