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公开(公告)号：EP3291498A4
公开(公告)日：2018-07-18
申请号：EP16786795
申请日：2016-04-29
发明人： LEE KEON-KOOK , PARK SUN-HO , SHIM BYONG-HYO , KIM TAE-YOUNG , SEOL JI-YUN
CPC分类号： H04L25/0236 , H04L25/0204 , H04L25/03891
摘要： The present disclosure relates to a 5G or pre-5G communication system to be provided to support a higher data transmission rate beyond the 4G communication system, such as LTE. The present invention provides a method for estimating a downlink channel by a receiver in a wireless communication system, the method comprising: estimating the downlink channel on the basis of a reference signal to recover an information bit, and checking whether the information bit recovery has succeeded; and when the information bit recovery has not succeeded, selecting at least one of the received signals as a virtual reference signal on the basis of the accuracy of the data reconstructed at a related resource location and the correlation between the related resource location and a resource location related to the reference signal, and estimating the downlink channel on the basis of at least one virtual reference signal.
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公开(公告)号：EP3214178A4
公开(公告)日：2018-07-11
申请号：EP15854007
申请日：2015-10-29
发明人： CHUNG JONG HOON , GARG PANKAJ , PANDEY SHAMBHAVI , CHOUNG PILL HOON , CHO CHONG SU , KIM BOG HEE
IPC分类号： A61K47/50 , A61K48/00 , C12N15/113 , C12N15/87
CPC分类号： C12N15/1137 , A61K9/0019 , A61K9/007 , A61K31/7088 , A61K47/551 , A61K47/59 , A61K48/00 , C08G73/024 , C12N2310/14 , C12N2320/32
摘要： The present invention relates to polydixylitol polymer based gene transporter (PdXYP) and a preparation method thereof. Further, the present invention relates to a nucleic acid delivery complex where the nucleic acids for treatment are conjugated to the gene transporter and a pharmaceutical composition for gene therapy including the complex as an active ingredient. In addition, the present invention relates to the gene transporter, gene delivery complex, and gene therapy using the gene transporter and gene delivery complex. It was confirmed that the PdXYP of the present invention has a considerably higher nucleic acid delivery rate than existing gene transporters, has almost no cytotoxicity in the conjugate when conjugated with DNA, also has very high in vivo transfection efficiency, and above all, especially has considerably high transfection efficiency for brain tissues, which has involved difficulty in gene therapy due to the blood brain barrier for a while. Accordingly, the gene transporter of the present invention can not only be used as experimental gene transporters, but can also be broadly used for various tissues in the body based on the nucleic acids for treatment to be conjugated in the field of gene therapy regarding various diseases.
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公开(公告)号：EP3156438A4
公开(公告)日：2017-12-20
申请号：EP15806560
申请日：2015-06-12
发明人： CHOI SEONG HO , LEE JONG-CHAN , KIM HYUK , KIM DOYOUNG , KIM JI HUN , KO TAEYUN , JUNG BO-KYUNG , KIM KIHYUN
CPC分类号： C08J5/2275 , C08G75/23 , C08J5/22 , C08J2381/06 , C08K9/10 , C08L81/06 , H01M8/1032 , H01M8/1048 , H01M8/1051 , H01M2008/1095 , Y02P70/56
摘要： The present application relates to a composite electrolyte membrane and a method for manufacturing the same. The composite electrolyte membrane according to the present application includes: a poly(arylene ether sulfone) copolymer including the repeating unit represented by Chemical Formula 1 and the repeating unit represented by Chemical Formula 2; and a core-shell particle including an inorganic particle core and a basic organic polymer shell.
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公开(公告)号：EP3192822A4
公开(公告)日：2018-07-04
申请号：EP15867194
申请日：2015-12-11
发明人： LEE MI JIN , SOHN BYEONG-HYEOK , CHAE SEUNG YONG , KWON WON JONG , SOHN KWON NAM
IPC分类号： C08F293/00 , B01J19/00 , C01B32/19 , C08F212/08 , C08F283/06
CPC分类号： B01J19/0093 , B01J2219/0086 , B01J2219/00891 , C01B31/0469 , C01B32/19 , C08F283/06 , C08F293/00 , C08F293/005 , C08F2438/03
摘要： The present invention relates to a method for preparing graphene using a novel block copolymer. The present invention has features that, by using the block copolymer to mediate graphene that is hydrophobic and a solvent of a feed solution that is hydrophilic, the exfoliation efficiency of graphene as well as the dispersion stability thereof can be increased during high-pressure homogenization.
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5.发明公开
公开(公告)号：EP3219355A4
公开(公告)日：2018-05-16
申请号：EP15859039
申请日：2015-03-31
发明人： KIM DAE-HYEONG , HYEON TAEGHWAN , HWANG HYE JIN , PARK JINKYUNG , CHOI SUJI
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0597
摘要： The present invention relates to a mesh electrode for cardiac resynchronization therapy, and a manufacturing method therefor. More specifically, the present invention relates to: a mesh electrode for cardiac resynchronization therapy, formed from a wire composed of a first biocompatible rubber layer in which silver nanowires are dispersed, and a second biocompatible rubber layer formed so as to be adjacent to the first biocompatible rubber layer; and a manufacturing method therefor.
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6.发明公开
公开(公告)号：EP3208614A4
公开(公告)日：2018-05-09
申请号：EP15850998
申请日：2015-09-18
发明人： CHOI YONGHWAN , NAMKUNG JUNGHYUN , YI SUNG GON , HAN SANJO , JANG JIN-YOUNG , PARK TAESUNG , KIM YOUNGSOO
IPC分类号： G01N33/574
CPC分类号： G01N33/57438 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , G01N2333/4728
摘要： The present invention relates to a composition, a kit and a method for diagnosing pancreatic cancer, comprising an agent for measuring a protein or mRNA expression level of a certain marker gene available for determining the onset or the possibility of onset of pancreatic cancer. By providing the marker for diagnosing pancreatic cancer, an early diagnosis for the possibility of onset of pancreatic cancer or precancerous lesion and a significant prediction of the disease severity can be carried out, thereby being used for applied to a study on the tumorigenesis of pancreatic cancer. In addition, the diagnosis method of the present invention allows for the convenient detection of pancreatic cancer in a non-invasive manner in a sample such as blood.
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公开(公告)号：EP3189849A4
公开(公告)日：2018-04-04
申请号：EP15807777
申请日：2015-07-24
发明人： CHUNG CHONG PYOUNG , PARK YOON JEONG , LEE JUE YEON , SUH JIN SOOK , JO IN HO , PARK YOON SHIN
CPC分类号： A61K38/16 , A23L33/18 , A23V2002/00 , A61K9/0019 , A61K38/08 , C07K7/06 , C07K14/001 , A23V2200/332
摘要： The present invention relates to a fat accumulation inhibitory peptide which essentially comprises an amino acid sequence represented by SEQ ID NO: 1, a pharmaceutical composition for preventing or treating obesity, which contains the peptide, and a health functional food for preventing or alleviating obesity, which contains the peptide. The fat accumulation inhibitory peptide according to the present invention has the function of inhibiting the differentiation of mesenchymal stem cells into adipocytes to thereby inhibit the accumulation of adipose tissue. Thus, the peptide according to the present invention is highly useful for the prevention or treatment of obesity.
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公开(公告)号：EP3228085A4
公开(公告)日：2017-12-13
申请号：EP16783388
申请日：2016-04-20
发明人： SEO JE-HWAN , KIM DAE-SIK , SUH BONGWON , LEE JOONG-SEEK
IPC分类号： H04N21/258 , G06F3/01 , H04N5/44 , H04N21/41 , H04N21/422 , H04N21/4363 , H04N21/442 , H04N21/658 , H04W4/00 , H04W4/02
CPC分类号： H04N21/44218 , H04N21/25891 , H04N21/4126 , H04N21/42202 , H04N21/43637 , H04N21/44204 , H04N21/44222 , H04N21/6582 , H04W4/008 , H04W4/023
摘要： An electronic device includes a communicator comprising communication circuitry, and a controller configured to control the communicator to receive a beacon signal including content information, to acquire location information based on the beacon signal, and to transmit a packet to a server, the packet including the content information, the location information, and use log information.
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公开(公告)号：EP3186364A4
公开(公告)日：2018-04-04
申请号：EP15836684
申请日：2015-08-27
发明人： PARK SUNG SUP , KIM JI YEON
CPC分类号： C12N5/0621 , A61K35/30 , C12N2501/105 , C12N2501/115 , C12N2501/155 , C12N2501/385 , C12N2501/41 , C12N2501/415 , C12N2501/599 , C12N2506/02 , C12N2506/45 , G01N33/5058 , G01N2800/168
摘要： Provided are a method of preparing retinal ganglion cells by differentiation of stem into retinal ganglion cells, retinal ganglion cells differentiated by the method, a method of screening for a death inhibitor or a proliferation promoter of retinal ganglion cells using the retinal ganglion cells differentiated by the method, a kit of screening for the death inhibitor or the proliferation promoter of retinal ganglion cells including the retinal ganglion cells differentiated by the method, a pharmaceutical composition for treating glaucoma or optic neuropathy including the retinal ganglion cells, a method of treating glaucoma or optic neuropathy including the step of administering the retinal ganglion cells to a subject suspected of having glaucoma or optic neuropathy, and a method of preparing a mature retinal ganglion cell line.
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公开(公告)号：EP3248603A4
公开(公告)日：2017-12-27
申请号：EP16821505
申请日：2016-01-15
发明人： SEONG SEUNG YONG , CHO JUNG AH , KIM TAE JOO , KIM YOUN HEE
IPC分类号： A61K31/575 , A61K9/00 , A61K9/14 , A61K9/20 , A61P25/28
CPC分类号： A61K9/00 , A61K9/14 , A61K9/20 , A61K31/575
摘要： The present invention relates to a pharmaceutical composition for preventing, treating or delaying an Alzheimer's disease (AD) or dementia including a G protein-coupled receptor19 (GPCR19) agonist or its pharmaceutically acceptable salt as an active ingredient and a food composition for preventing, treating or delaying an Alzheimer's disease or dementia. The GPCR19 agonist according to the present invention has an effect of improving cognitive and behavioral disorders without harming the health of objects when administrated to the objects and has an effect of preventing the Alzheimer's disease or dementia or delaying or treating the progression of the disease in the objects with the disease by suppressing apoptosis of the brain tissue, enhancing immunity, and reducing formation of an amyloid ² (A²) plague.
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