摘要:
A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane derivative coating. An implantable stent device including a stent core having an oxidized surface with a layer of silane derivative covalently bonded thereto. A spacer layer comprising polyethylene glycol (PEG) is covalently bonded to the layer of silane derivative and a protein is covalently bonded to the PEG. A method of making a medical implant device including providing a substrate having a surface, oxidizing the surface and reacting with derivitized silane to form a silane coating covalently bonded to the surface. A bioactive agent is then covalently bonded to the silane coating. In particular instances, an additional coating of bio- absorbable polymer and/ or pharmaceutical agent is deposited over the bioactive agent.
摘要:
The present invention generally relates to a method and apparatus for mixing of fluids. More particularly, the present invention relates to a method and apparatus for mixing fluids introduced into near-critical and supercritical fluids forming a fluid stream. In the fluid stream a density gradient is generated that induces a convective velocity resulting in rapid mixing. The invention has application in such commercial applications as semiconductor and wafer fabrication where rapid cycle times or rapid mixing of fluids are required and where low tolerances for residues are permitted.
摘要:
A method for forming a continuous film on a substrate surface that involves depositing particles onto a substrate surface and contacting the particle-deposited substrate surface with a supercritical fluid under conditions sufficient for forming a continuous film from the deposited particles. The particles may have a mean particle size of less 1 micron. The method may be performed by providing a pressure vessel that can contain a compressible fluid. A particle-deposited substrate is provided in the pressure vessel and the compressible fluid is maintained at a supercritical or sub-critical state sufficient for forming a film from the deposited particles. The Tg of particles may be reduced by subjecting the particles to the methods detailed in the present disclosure.
摘要:
The present invention generally relates to methods for processing materials. More particularly, the present invention relates to reactive fluids and uses thereof for removing deposition materials, including, but not limited to, overburden materials, metals, non-metals, layered materials, organics, polymers, and semiconductor materials. The instant invention finds application in such commercial processes as semiconductor chip manufacturing.
摘要:
A method for depositing a substance on a substrate that involves forming a supercritical fluid solution of at least one supercritical fluid solvent and at least one solute, discharging the supercritical fluid solution through an orifice (10) under conditions sufficient to form solid particles of the solute that are substantially free of the supercritical fluid solvent, and electrostatically depositing the solid solute particles onto the substrate (13) . The solid solute particles may be charged to a first electric potential and then deposited onto the substrate (13) to form a film. The solute particles may have a mean particle size of less than 1 micron.
摘要:
A medical implant device having a substrate with an oxidized surface and a silane derivative coating covalently bonded to the oxidized surface. A bioactive agent is covalently bonded to the silane derivative coating. An implantable stent device including a stent core having an oxidized surface with a layer of silane derivative covalently bonded thereto. A spacer layer comprising polyethylene glycol (PEG) is covalently bonded to the layer of silane derivative and a protein is covalently bonded to the PEG. A method of making a medical implant device including providing a substrate having a surface, oxidizing the surface and reacting with derivitized silane to form a silane coating covalently bonded to the surface. A bioactive agent is then covalently bonded to the silane coating. In particular instances, an additional coating of bio- absorbable polymer and/ or pharmaceutical agent is deposited over the bioactive agent.
摘要:
The present invention generally relates to a system for cleaning substrates. More particularly, the present invention relates to process(es) for effecting chemical removal of residues from semiconductor substrates, including silicon wafers, using a system of reactive reverse micelle(s) or microemulsions in a densified carbon dioxide matrix. Various reactive chemical agents in the reactive micelle system may be used to effect cleaning and removal of etch and metal residues to levels sufficient for commercial wafer production and processing.
摘要:
Système de microémulsion comprenant une première phase comportant une matière fluide à faible polarité, laquelle est un gaz à température et à pression normales, et ayant une densité de point de trouble. Il comporte également une seconde phase comprenant un fluide polaire, typiquement de l'eau, un monomère, de préférence un monomère soluble dans le fluide polaire, ainsi qu'un promoteur de microémulsion facilitant la formation de micelles renfermant le monomère dans le système. Dans le procédé en question, les micelles renfermant le monomère sont formées dans la première phase. On introduit un initiateur de polymérisation dans les micelles se trouvant dans le système de microémulsion. Le monomère est ensuite polymérisé dans les micelles, de préférence dans le noyau de la micelle, afin de produire une matière polymère ayant un poids moléculaire relativement élevé.