-
公开(公告)号：EP3609870A1
公开(公告)日：2020-02-19
申请号：EP18713990.2
申请日：2018-04-04
发明人： BECK, Hartmut , KAST, Raimund , MEININGHAUS, Mark , FÜRSTNER, Chantal , STELLFELD, Timo , VON BÜHLER, Clemens-Jeremias , DIETZ, Lisa , BAIRLEIN, Michaela , ANLAHR, Johanna , JÖRISSEN, Hannah , HAUFF, Peter , MÜLLER, Jörg , DRÖBNER, Karoline , NAGEL, Jens
IPC分类号： C07D215/50 , A61K31/47 , A61P11/00 , A61P17/00 , A61P27/00
-
公开(公告)号：EP3609869A1
公开(公告)日：2020-02-19
申请号：EP18713989.4
申请日：2018-04-04
发明人： BECK, Hartmut , KAST, Raimund , MEININGHAUS, Mark , DIETZ, Lisa , FÜRSTNER, Chantal , STELLFELD, Timo , ANLAUF, Sonja , VON BÜHLER, Clemens-Jeremias , BAIRLEIN, Michaela , ANLAHR, Johanna , MÜNSTER, Uwe , TERJUNG, Carsten , JÖRISSEN, Hannah , HAUFF, Peter , MÜLLER, Jörg , DRÖBNER, Karoline , NAGEL, Jens
IPC分类号： C07D215/50 , A61K31/47 , A61P11/00 , A61P17/00 , A61P27/02
-
3.发明公开SUBSTITUIERTE N-BICYCLO-2-ARYLCHINOLIN-4-CARBOXAMIDE UND IHRE VERWENDUNG 审中-公开取代的N-二环-2-芳基氨基-4-甲酰胺及其用途
公开(公告)号：EP3271334A1
公开(公告)日：2018-01-24
申请号：EP16709919.1
申请日：2016-03-15
发明人： BECK, Hartmut , THALER, Tobias , KAST, Raimund , MEININGHAUS, Mark , TERJUNG, Carsten , MUENSTER, Uwe , OLENIK, Britta
IPC分类号： C07D215/52 , C07D405/12 , C07D409/04 , A61K31/47 , A61K31/4725 , A61P11/00
CPC分类号： A61K31/47 , A61K31/16 , A61K31/195 , C07D215/52 , C07D405/12 , C07D409/04
摘要： The invention relates to novel substituted N-bicyclo-2-aryl-quinoline-4-carboxamide derivatives, to methods for the production thereof, to the use thereof either alone or in combination for treating and/or preventing diseases and to their use for producing medicaments for treating and/or preventing diseases, especially for the treatment and/or prevention of fibrotic and inflammatory diseases.
-
4.发明公开CHIRALE 2,5-DISUBSTITUIERTE CYCLOPENTANCARBONSÄURE-DERIVATE UND IHRE VERWENDUNG 审中-公开CHIRALE 2,5-DISUBSTITUIERTECYCLOPENTANCARBONSÄURE-DERIVATE UND IHRE VERWENDUNG
公开(公告)号：EP3126340A2
公开(公告)日：2017-02-08
申请号：EP15741870.8
申请日：2015-03-31
发明人： BECK, Hartmut , LI, Volkhart Min-Jian , TIMMERMANN, Andreas , BOGNER, Pamela , CANCHO GRANDE, Yolanda , BROHM, Dirk , GERISCH, Michael , JÖRISSEN, Hannah , LANG, Dieter
IPC分类号： C07D253/08
CPC分类号： A61K31/53 , A61K45/06 , C07D253/08
摘要： The present invention relates to novel, chiral 2,5- disubstituted cyclopentanecarboxylic acid derivatives, to a method for the production thereof, to the use thereof alone or in combinations for the treatment and/or prophylaxis of diseases, and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of respiratory tracts, the lungs and the cardiovascular system.
摘要翻译： 本申请涉及新的手性2,5-二取代的环戊烷羧酸衍生物，其制备方法，其本身或组合用于治疗和/或预防疾病及其用于制备药物的用途 用于治疗和/或预防疾病，特别是用于治疗和/或预防呼吸道，肺和心血管系统的疾病。
-
5.发明公开
公开(公告)号：EP3215498A1
公开(公告)日：2017-09-13
申请号：EP15788389.3
申请日：2015-10-30
发明人： SCHMECK, Carsten , GERISCH, Michael , GRIEBENOW, Nils , KOLKHOF, Peter , KÖLLING, Florian , ENGELEN, Anna , KRETSCHMER, Axel , LANG, Dieter , LUSTIG, Klemens , MONDRITZKI, Thomas , POOK, Elisabeth , BECK, Hartmut , SÜSSMEIER, Frank , VOLLMER, Sonja , WASNAIRE, Pierre
IPC分类号： C07D403/06 , A61K31/4196 , A61P9/00 , A61P13/00
CPC分类号： C07D249/12 , A61K31/4196 , A61K45/06 , C07D403/06
摘要： The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
摘要翻译： 本发明涉及新的5-（羟基烷基）-1-苯基-1,2,4-三唑衍生物，涉及这些化合物的制备方法，涉及含有这些化合物的药物组合物，以及涉及这些化合物或组合物 用于治疗和/或预防疾病，特别是用于治疗和/或预防心血管和肾疾病。
-
公开(公告)号：EP3215498B1
公开(公告)日：2018-08-22
申请号：EP15788389.3
申请日：2015-10-30
发明人： SCHMECK, Carsten , GERISCH, Michael , GRIEBENOW, Nils , KOLKHOF, Peter , KÖLLING, Florian , ENGELEN, Anna , KRETSCHMER, Axel , LANG, Dieter , LUSTIG, Klemens , MONDRITZKI, Thomas , POOK, Elisabeth , BECK, Hartmut , SÜSSMEIER, Frank , VOLLMER, Sonja , WASNAIRE, Pierre
IPC分类号： C07D403/06 , A61K31/4196 , A61P9/00 , A61P13/00
CPC分类号： C07D249/12 , A61K31/4196 , A61K45/06 , C07D403/06
摘要： The present invention relates to novel 5-(hydroxyalkyl)-1-phenyl-1,2,4-triazole derivatives, to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular and renal diseases.
-
7.发明公开2,5-DISUBSTITUIERTE CYCLOPENTANCARBONSÄUREN ZUR BEHANDLUNG VON ATEMWEGSERKRANKUNGEN 审中-公开紫杉醇环氧树脂（ZUR BEHANDLUNG VON ATEMWEGSERKRANKUNGEN）
公开(公告)号：EP3126358A1
公开(公告)日：2017-02-08
申请号：EP15712926.3
申请日：2015-03-31
发明人： BECK, Hartmut , LI, Volkhart Min-Jian , CANCHO GRANDE, Yolanda , TIMMERMANN, Andreas , BROHM, Dirk , JÖRISSEN, Hannah , BOGNER, Pamela , GERISCH, Michael , LANG, Dieter
IPC分类号： C07D405/12 , A61K31/53 , A61P37/00 , A61P11/00
CPC分类号： C07D405/12 , A61K9/0053 , A61K9/08 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/2059 , A61K31/53 , A61K45/06 , A61K47/10 , A61K47/26 , C07D253/08
摘要： The invention relates to novel 2,5-disubstituted cyclopentane carboxylic acid derivatives, to methods for the preparation thereof, to the use thereof alone or in combination for the treatment and/or prevention of disorders, and to the use thereof for producing medicaments for the treatment and/or prevention of disorders, especially for treatment and/or prevention of diseases of the respiratory tract, lung and of the cardiovascular system.
摘要翻译： 本申请涉及新的2,5-二取代的环戊烷羧酸衍生物，其制备方法，单独使用或组合用于治疗和/或预防疾病及其用于生产用于治疗和/ 或预防疾病，特别是用于治疗和/或预防呼吸，肺和心血管疾病。
-
公开(公告)号：EP3126339A1
公开(公告)日：2017-02-08
申请号：EP15712934.7
申请日：2015-03-31
发明人： BECK, Hartmut , LI, Volkhart Min-Jian , CANCHO GRANDE, Yolanda , TIMMERMANN, Andreas , BROHM, Dirk , JÖRISSEN, Hannah , BOGNER, Pamela , GERISCH, Michael , LANG, Dieter
IPC分类号： C07D253/08 , A61K31/19
CPC分类号： C07D253/08 , A61K31/53 , A61K45/06 , C07D413/12
摘要： The invention relates to novel 2,5-disubstituted cyclopentane carboxylic acid derivatives, to methods for the preparation thereof, to the use thereof alone or in combination for the treatment and/or prevention of disorders, and to the use thereof for producing medicaments for the treatment and/or prevention of disorders, especially for treatment and/or prevention of diseases of the respiratory tract, lung and of the cardiovascular system.
摘要翻译： 本申请涉及新的2,5-二取代的环戊烷羧酸衍生物，其制备方法，单独使用或组合用于治疗和/或预防疾病及其用于生产用于治疗和/ 或预防疾病，特别是用于治疗和/或预防呼吸，肺和心血管疾病。
-
9.发明公开SUBSTITUIERTE N,2-DIARYLCHINOLIN-4-CARBOXAMIDE UND IHRE ANTI-INFLAMMATORISCHE VERWENDUNG 审中-公开SUBSTITUIERTE N，2-DIARYLCHINOLIN-4-CARBOXAMIDE和IHRE抗炎药物 - 维生素E
公开(公告)号：EP3191452A1
公开(公告)日：2017-07-19
申请号：EP15757299.1
申请日：2015-09-07
发明人： BECK, Hartmut , THALER, Tobias , KAST, Raimund , MEIBOM, Daniel , MEININGHAUS, Mark , TERJUNG, Carsten , DELBECK, Martina , LUSTIG, Klemens , MUENSTER, Uwe , OLENIK, Britta
IPC分类号： C07D215/52 , C07D215/60 , C07D401/12 , A61K31/47 , A61P11/00 , A61P37/00
CPC分类号： C07D215/52 , C07D215/60 , C07D401/04 , C07D401/12
摘要： The invention relates to novel substituted N,2-diarylquinoline-4-carboxamide derivatives, to methods for producing the same, to the use thereof either alone or in combination in the treatment and/or prevention of diseases and to their use for producing drugs for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of fibrotic and inflammatory diseases.
摘要翻译： 本发明涉及新的取代的N，2-二芳基喹啉-4-甲酰胺衍生物，其制备方法，其单独或组合用于治疗和/或预防疾病及其用于制备用于 治疗和/或预防疾病，特别是用于治疗和/或预防纤维化和炎性疾病。
-
10.发明公开
公开(公告)号：EP2569312A1
公开(公告)日：2013-03-20
申请号：EP11716595.1
申请日：2011-05-03
发明人： HÄRTER, Michael , BECK, Hartmut , GRESCHAT-SCHADE, Susanne , ELLINGHAUS, Peter , UNTERSCHEMMANN, Kerstin , SCHUHMACHER, Joachim
IPC分类号： C07D413/14 , A61K31/4245 , A61P35/00
CPC分类号： A61K31/454 , A61K31/4245 , A61K45/06 , C07D413/14
摘要： The application relates to novel substituted 1-[3-(heterocyclyl)benzyl]-1
H -pyrazole derivatives, methods for the production thereof, the use thereof for the treatment and/or prevention of diseases, and the use thereof for the production of medicaments used for the treatment and/or prevention of diseases, in particular hyperproliferative and angiogenic diseases as well as diseases caused by metabolic adaptation to hypoxic conditions. Such treatments can be administered as monotherapy or in combination with other medicaments or other therapeutic measures.
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.022 秒)
