公开(公告)号：EP2155659A1

公开(公告)日：2010-02-24

申请号：EP08749469.6

申请日：2008-05-09

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： RUDOLPH, Joachim ,  DUMAS, Jaques ,  LI, Yingfu ,  AUCLAIR, Daniel ,  LOBELL, Mario ,  HITCHCOCK, Marion ,  HARTUNG, Ingo ,  KOPPITZ, Marcus ,  BRITTAIN, Dominic ,  PUEHLER, Florian ,  PETERSEN, Kirstin ,  GUENTHER, Judith ,  BADER, Benjamin

IPC分类号： C07C217/92 ,  C07C233/65 ,  C07C255/59 ,  C07C271/16 ,  C07C307/10 ,  C07D211/22 ,  C07D317/22 ,  C07D497/04 ,  C07D295/088 ,  A61K31/136 ,  A61K31/4465 ,  A61K31/277 ,  A61K31/167 ,  A61K31/357 ,  A61K31/495

CPC分类号： C07D233/60 ,  C07C217/92 ,  C07C237/30 ,  C07C237/44 ,  C07C243/38 ,  C07C255/58 ,  C07C255/59 ,  C07C271/16 ,  C07C271/28 ,  C07C271/44 ,  C07C275/28 ,  C07C275/36 ,  C07C307/02 ,  C07C307/10 ,  C07C309/66 ,  C07C311/08 ,  C07C311/09 ,  C07C311/17 ,  C07C311/48 ,  C07C2601/08 ,  C07C2601/10 ,  C07D205/04 ,  C07D207/08 ,  C07D207/27 ,  C07D207/48 ,  C07D209/08 ,  C07D211/22 ,  C07D211/46 ,  C07D211/96 ,  C07D213/30 ,  C07D213/34 ,  C07D213/68 ,  C07D231/18 ,  C07D233/84 ,  C07D265/30 ,  C07D277/22 ,  C07D295/088 ,  C07D295/185 ,  C07D295/26 ,  C07D317/22 ,  C07D317/64 ,  C07D327/04 ,  C07D403/12

摘要： This invention relates to novel substituted phenylamino-benzene compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper- proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.

摘要翻译： 本发明涉及新的substituiertem苯氨基苯化合物，药物组合物含有受试化合物和用于治疗过度增殖和/或血管生成病症，作为唯一的药物或与其它活性成分组合使用这些化合物或组合物。

公开(公告)号：EP2152672A1

公开(公告)日：2010-02-17

申请号：EP08749502.4

申请日：2008-05-23

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： EIS, Knut ,  PRIEN, Olaf ,  LUECKING, Ulrich ,  GUENTHER, Judith ,  ZOPF, Dieter ,  BROHM, Dirk ,  VÖHRINGER, Verena ,  WOLTERING, Elisabeth ,  BECK, Hartmut ,  LOBELL, Mario ,  LI, Volkhart, Min-Jian ,  GRESCHAT, Susanne

IPC分类号： C07D215/233 ,  C07D215/42 ,  C07D215/44 ,  C07D239/94 ,  C07D401/12 ,  A61K31/4706 ,  A61K31/4709 ,  A61K31/47 ,  A61P35/00 ,  A61P25/28

CPC分类号： C07D239/86 ,  C07D215/44 ,  C07D409/04

摘要： The present invention relates to a quinoline or quinazoline derivative having the general formula (A): in which R3, R4, W, Y and Q are indicated in the description and the claims, the use of the compounds of the general formula (A) for the treatment of various disorders, and the preparation of compounds of the general formula (A).

公开(公告)号：EP2001890B1

公开(公告)日：2011-01-12

申请号：EP07753547.4

申请日：2007-03-20

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： ZHANG, Chengzhi ,  SIDHU, Kanwar ,  LOBELL, Mario ,  LADOUCEUR, Gaetan ,  ZHAO, Qian ,  LIU, Zheng ,  ALLEGUE, Kristen, M. ,  DARNE, Chetan, P. ,  NEWCOM, Jason

IPC分类号： C07D495/14

CPC分类号： C07D495/14

摘要： This invention relates to compounds of Formula (I), wherein the variables are as disclosed in the specification, to pharmaceutical compositions containing them, to methods of making the compounds and pharmaceutical compositions, and to methods of using the compounds and pharmaceutical compositions for treating or preventing disorders, in particular cancer.

公开(公告)号：EP2212332A1

公开(公告)日：2010-08-04

申请号：EP08785784.3

申请日：2008-09-02

申请人： Bayer Schering Pharma Aktiengesellschaft

发明人： SCHIROK, Hartmut ,  LI-SOMMER, Ying ,  BRANDS, Michael ,  LOBELL, Mario ,  TERSTEEGEN, Adrian ,  HIMMEL, Herbert ,  SCHLEMMER, Karl-Heinz ,  LANG, Dieter ,  PETERSEN, Kirstin ,  RENZ, Matthias ,  MUMBERG, Dominik ,  HOFFMANN, Jens ,  SIEMEISTER, Gerhard ,  BÖMER, Ulf

IPC分类号： C07D495/14 ,  C07D519/00 ,  C07D491/147 ,  A61K31/33 ,  A61P35/00

CPC分类号： C07D495/14 ,  C07D491/147 ,  C07D519/00

摘要： This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.