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    COMPOSITIONS COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF
    4.
    发明公开
    COMPOSITIONS COMPRISING VARIOUS PROTEORHODOPSINS AND/OR BACTERIORHODOPSINS AND USE THEREOF 有权
    ZUSAMMENSETZUNGEN MIT VERSCHIEDENEN PROTEORHODOPSINEN UND / ODER BAKTERIORHODOPSINEN UND DEREN VERWENDUNG

    公开(公告)号：EP1753448A4

    公开(公告)日：2009-09-02

    申请号：EP05761082

    申请日：2005-06-09

    申请人： GENENCOR INT ,  DOW CORNING

    发明人： BOTT RICHARD R ,  JENSEN RASMUS B ,  KELEMEN BRADLEY ,  WARD DONALD E II ,  WHITED GREGORY M

    IPC分类号： C07K14/00 ,  A61K38/17 ,  C07K14/215 ,  C07K14/705 ,  C09D11/00

    CPC分类号： G11C7/00 ,  C07K14/215 ,  C09D11/037 ,  C09D11/50 ,  G11B7/242 ,  Y10S430/146 ,  Y10T428/249921 ,  Y10T428/31623 ,  Y10T428/31685 ,  Y10T428/31725 ,  Y10T428/31783

    摘要： The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal- containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate. The present invention further provides security ink comprising one or more hydrophilic polymers and a mixture of various photochromic materials.

    摘要翻译： 本发明提供一种固体材料，其包含两种或更多种proteorhodopsins，两种或更多种细菌视紫红质或一种或更多种细菌视紫红质和一种或更多种proteorhodopsins的固定化混合物。 该proteorhodopsins选自全反式视网膜proteorhodopsins和含视网膜类似物proteorhodopsins; 所有这些都具有不重叠的吸收光谱。 细菌视紫红质选自含全反式视黄醛的细菌视紫红质和含视网膜模拟物的细菌视紫红质; 所有这些都具有不重叠的吸收光谱。 本发明还提供一种光学信息载体，例如光学数据存储材料和防欺诈光学数据载体，其包括上述固体材料和选自玻璃，纸，金属，织物材料 和塑料材料，其中所述固体材料沉积在所述基材上。 本发明进一步提供包含一种或多种亲水性聚合物和各种光致变色材料的混合物的安全油墨。

    HIGH THROUGHPUT MUTAGENESIS SCREENING METHOD
    5.
    发明公开
    HIGH THROUGHPUT MUTAGENESIS SCREENING METHOD 有权
    具有高吞吐量诱变筛选过程

    公开(公告)号：EP1543117A4

    公开(公告)日：2007-06-20

    申请号：EP03744218

    申请日：2003-03-05

    申请人： GENENCOR INT

    发明人： BOTT RICHARD R ,  KELLIS JAMES T JR ,  MORRISON THOMAS B

    IPC分类号： C12N9/18 ,  C12N9/20

    CPC分类号： C12Y301/01074 ,  C12N9/18

    摘要： The present invention provides mutagenesis methods for protein engineering. In particular, the present inventionprovides mutagenesis methods that include feedback adjustment from systematic result evaluation. More specifically, the invention provides site-saturation mutagenesis methods that screen for variants with one or more desirable protein properties and evaluates screening results to provide feedback for repeat screening and construction of new libraries. The invention further provides cutinase variants that provide improved stability and activity compared with the wild type cutinase.