公开(公告)号：EP1392852A2

公开(公告)日：2004-03-03

申请号：EP02752013.9

申请日：2002-05-31

申请人： Incyte Genomics, Inc. ,  Yue, Henry

发明人： YUE, Henry ,  TANG, Y., Tom ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  WARREN, Bridget, A. ,  WALIA, Narinder, K. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  HAFALIA, April, J.A. ,  RICHARDSON, Thomas, W. ,  GRIFFIN, Jennifer, A. ,  EMERLING, Brooke, M. ,  RAMKUMAR, Jayalaxmi ,  YUE, Huibin ,  SWARNAKAR, Anita ,  TRAN, Bao ,  LI, Joana, X. ,  YAO, Monique, G. ,  YANG, Junming ,  ISON, Craig H. ,  FORSYTHE, Ian J. . ,  HONCHELL, Cynthia D. ,  ARVIZU, Chandra S. ,  ELLIOTT, Vicki S. ,  LU, Yan ,  DING, Li ,  LUO, Wen ,  WANG, Yu-Mei E. ,  BURFORD, Neil ,  BOROWSKY, Mark L. ,  NGUYEN, Danniel B. ,  CHINN, Anna M. ,  KABLE, Amy E.

IPC分类号： C12Q1/48 ,  C12N9/10 ,  A61K38/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12Q1/6883 ,  C12Q2600/158

摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与NAAP的异常表达相关的病症的方法。

公开(公告)号：EP1478745A2

公开(公告)日：2004-11-24

申请号：EP02731940.9

申请日：2002-05-23

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  AZIMZAI, Yalda ,  DING, Li ,  LEE, Ernestine, A. ,  HAFALIA, April, J., A. ,  BECHA, Shanya, D. ,  TANG, Y., Tom ,  LAL, Preeti, G. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  RAMKUMAR, Jayalaxmi ,  ELLIOTT, Vicki, S. ,  ARVIZU, Chandra, S. ,  LUO, Wen ,  SWARNAKAR, Anita ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  GANDHI, Ameena R. ,  YAO, Monique G. ,  KHAN, Farrah A. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas W. ,  MARQUIS, Joseph P. ,  CHIEN, David ,  JIN, Pei

IPC分类号： C12N9/20 ,  C12N9/14 ,  C12N15/00 ,  C12N5/00 ,  C12N1/20 ,  C07K1/00 ,  C07H21/04 ,  C07H21/02 ,  C12Q1/68

CPC分类号： C12N9/1205 ,  C12N9/16

摘要： The invention provides human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明提供了识别和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1390410A1

公开(公告)日：2004-02-25

申请号：EP02739428.7

申请日：2002-05-24

申请人： Incyte Genomics, Inc.

发明人： TANG, Tom, Y. ,  YUE, Henry ,  BAUGHN, Mariah, R. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  BANDMAN, Olga ,  RICHARDSON, Thomas, W. ,  BURFORD, Neil ,  SANJANWALA, Bharati ,  BECHA, Shanya, D. ,  YAO, Monique, G. ,  YANG, Junming ,  TRAN, Uyen, K. ,  HAFALIA, April, J.A. ,  GRIFFIN, Jennifer, A. ,  SWARNAKAR, Anita ,  ELLIOTT, Vicki, S. ,  RECIPON, Shirley, A. ,  KHAN, Farrah, A. ,  LEE, Ernestine A. ,  YUE, Huibin ,  LU, Dyung Aina M. ,  CHAWLA, Narinder K. ,  THANGAVELU, Kavitha ,  ARVIZU, Chandra S. ,  XU, Yuming ,  ISON, Craig H. ,  HUANG, Jiaqi ,  DING, Li ,  HONCHELL, Cynthia D. ,  BOROWSKY, Mark L. ,  EMERLING, Brooke M. ,  PETERSON, David P. ,  LU, Yan ,  RAMKUMAR, Jayalaxmi ,  MASON, Patricia M. ,  ZEBARJADIAN, Yeganeh ,  AZIMZAI, Yalda ,  STUVE, Laura L. ,  KAMIGAKI, Laura L. ,  BARROSO, Ines ,  LEE, Sally ,  KABLE, Amy E.

IPC分类号： C07K17/00 ,  G01N33/53 ,  A61K39/00

CPC分类号： G01N33/5008 ,  A61K38/00 ,  C07K14/47 ,  C12Q1/6837 ,  C12Q1/6883 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/68 ,  G01N33/6845 ,  G01N2500/00 ,  G01N2500/04

摘要： The invention provides human molecules for disease detection and treatment (MDDT)and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methodsfor diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1320600A1

公开(公告)日：2003-06-25

申请号：EP01959424.1

申请日：2001-08-01

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  THORNTON, Michael ,  RAMKUMAR, Jayalaxmi ,  TANG, Y. Tom ,  AZIMZAI, Yalda ,  BAUGHN, Mariah R. ,  YANG, Junming ,  YAO, Monique G. ,  LAL, Preeti ,  WALIA, Narinder K. ,  GANDHI, Ameena R. ,  HAFALIA, April J.A. ,  NGUYEN, Danniel B. ,  PATTERSON, Chandrea ,  ELLIOTT, Vicki S. ,  TRIBOULEY, Catherine M. ,  LU, DYUNG, Aina M. ,  XU, Yuming ,  REDDY, Roopa ,  HERNANDEZ, Roberto ,  BOROWSKY, Mark L. ,  LO, Terence P. ,  LU, Yan ,  POLICKY, Jennifer L. ,  GREENE, Barrie D. ,  SANJANWALA, Madhu S. ,  RAUMANN, Brigitte E. ,  BURFORD, Neil ,  ISON, Craig H. ,  LEE, Ernestine A. ,  DING, Li ,  DAS, Debopriya ,  KALLICK, Deborah A. ,  KHAN, Farrah A. ,  SEILHAMER, Jeffrey J.

IPC分类号： C12N15/12 ,  C12N15/11 ,  C12N15/63 ,  C12N1/21 ,  C12N5/10 ,  C07K14/47 ,  C07K14/705 ,  C07K16/18 ,  C07K16/28 ,  A01K67/027 ,  C12Q1/68 ,  G01N33/68 ,  A61K38/17 ,  A61K39/395

CPC分类号： C07K14/47 ,  C07K14/705

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

公开(公告)号：EP1417224A2

公开(公告)日：2004-05-12

申请号：EP02763529.1

申请日：2002-08-15

申请人： Incyte Genomics, Inc.

发明人： TANG, Tom, Y. ,  WARREN, Bridget, A. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  YUE, Henry ,  HONCHELL, Cynthia, D. ,  LEHR-MASON, Patricia, M. ,  BURFORD, Neil ,  XU, Yuming ,  BAUGHN, Mariah, R. ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  LEE, Ernestine, A. ,  FORSYTHE, Ian, J. ,  RICHARDSON, Thomas, W. ,  LEE, Sally ,  THANGAVELU, Kavitha ,  YUE, Huibin ,  EMERLING, Brooke, M. ,  CHAWLA, Narinder K. ,  AZIMZAI, Yalda ,  SANJANWALA, Bharati ,  HAFALIA, April J.A. ,  BOROWSKY, Mark L. ,  NGUYEN, Danniel B. ,  ISON, Craig H. ,  ASTROMOFF, Anna ,  DING, Li ,  LEE, Soo Yeun ,  BECHA, Shanya D. ,  RAMKUMAR, Jayalaxmi ,  GANDHI, Ameena r. ,  JIN, Pei ,  FU, Glenn K. ,  SWARNAKAR, Anita

IPC分类号： C07K14/00 ,  C12P21/06 ,  A61K38/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/705 ,  C12N9/1205 ,  C12N9/16 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。

公开(公告)号：EP1373517A2

公开(公告)日：2004-01-02

申请号：EP01987811.5

申请日：2001-10-20

申请人： Incyte Genomics, Inc.

发明人： GURURAJAN, Rajagopal ,  BAUGHN, Mariah, R. ,  Chawla, Narinder, K. ,  ELLIOTT, Vicki, S. ,  XU, Yuming ,  ARVIZU, Chandra ,  YAO, Monique, G. ,  RAMKUMAR, Jaya ,  DING, Li ,  TANG, Y., Tom ,  HAFALIA, April, J., A. ,  NGUYEN, Daniel, B. ,  GANDHI, Ameena, R. ,  LU, Yan ,  YUE, Henry ,  BURFORD, Neil ,  BANDMAN, Olga ,  TRIBOULEY, Catherine, M. ,  LAL, Preeti, G. ,  RECIPON, Shirley A. ,  LU, Dyung Aina M. ,  BOROWSKY, Mark L. ,  THORNTON, Michael ,  SWARNAKER, Anita ,  THANGAVELU, Kavitha ,  KHAN, Farrah A. ,  ISON, Craig H.

IPC分类号： C12N15/54 ,  C12N9/12 ,  A01K67/027 ,  C07K16/40 ,  C12Q1/68 ,  C12Q1/48 ,  G01N33/50 ,  A61K38/45

CPC分类号： C12N9/12 ,  A01K2217/05 ,  A61K38/00

摘要： The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.

公开(公告)号：EP1504101A2

公开(公告)日：2005-02-09

申请号：EP02786702.7

申请日：2002-11-07

申请人： Incyte Genomics, Inc.

发明人： KABLE, Amy, E. ,  SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J.A. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  EMERLING, Brooke, M. ,  ISON, Craig, H. ,  NGUYEN, Danniel, B. ,  LINDQUIST, Erika, A. ,  LEE, Ernestine, A. ,  YUE, Henry ,  YUE, Huibin ,  FORSYTHE, Ian, J. ,  RAMKUMAR, Jayalaxmi ,  GRIFFIN, Jennifer, A. ,  LI, Joana, X. ,  MARQUIS, Joseph, P. ,  GIETZEN, Kimberly, J. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  YAO, Monique G. ,  CHAWLA, Narinder K. ,  LEHR-MASON, Patricia M. ,  LAL, Preeti G. ,  GURURAJAN, Rajagopal ,  KHARE, Reena ,  BATRA, Sajeev ,  BECNA, Shanya, D. ,  LEE, Soo Yeun ,  TRAN, Uyen K. ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  TANG, Y. Tom ,  ZEBARJADIAN, Yeganeh ,  JIANG, Xin ,  JACKSON, Alan A. ,  BHATIA, Umesh ,  BURRILL, John D. ,  LEE, Sally ,  BLAKE, Julie J. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C12N15/63 ,  C12N15/85 ,  C07K14/00 ,  C07K16/00

CPC分类号： C07K14/47

摘要： Various ernbodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

公开(公告)号：EP1434796A2

公开(公告)日：2004-07-07

申请号：EP02776174.1

申请日：2002-10-03

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  TRAN, Uyen, K. ,  DUGGAN, Brendan, M. ,  THANGAVELU, Kavitha ,  YANG, Junming ,  XU, Yuming ,  TANG, Tom, Y. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  FORSYTHE, Ian, J. ,  BECHA, Shanya, D. ,  YAO, Monique, G. ,  EMERLING, Brooke, M. ,  GRIFFIN, Jennifer, A. ,  LAL, Preeti, G. ,  ZEBARJADIAN, Yeganeh ,  BAUGHN, Mariah, R. ,  LEE, Ernestine A. ,  LEE, Soo Yeun ,  RAMKUMAR, Jayalaxmi ,  GORVAD, Ann E. ,  KABLE, Amy E. ,  LU, Dyung Aina M. ,  BOROWSKY, Mark L.

IPC分类号： C07K14/475 ,  A61K38/18

CPC分类号： C07K14/47 ,  A01K2217/05 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。

公开(公告)号：EP1423415A2

公开(公告)日：2004-06-02

申请号：EP02793765.5

申请日：2002-08-16

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  GRIFFIN, Jennifer, A. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  YAO, Monique, G. ,  RAMKUMAR, Jayalaxmi ,  RICHARDSON, Thomas, W. ,  BECHA, Shanya, D. ,  LEE, Ernestine, A. ,  WARREN, Bridget, A. ,  LEHR-MASON, Patricia, M. ,  BAUGHN, Mariah, R. ,  LI, Joana, X. ,  DUGGAN, Brendan, M. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  BOROWSKY, Mark L. ,  ISON, Craig H. ,  THANGAVELU, Kavitha ,  XU, Yuming ,  LEE, Sally ,  ELLIOTT, Vicki S. ,  SPRAGUE, William W. ,  AZIMZAI, Yalda ,  HAFALIA, April J.A. ,  DING, Li ,  NGUYEN, Danniel B. ,  HONCHELL, Cynthia D. ,  LUO, Wen ,  CHWALA, Narinder K. ,  MARQUIS, Joseph P. ,  JACKSON, Jennifer L. ,  TRAN, Uyen K.

IPC分类号： C07K14/00

CPC分类号： C07K14/4702 ,  A61K38/00 ,  C07K14/47 ,  G01N2500/04

摘要： Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

摘要翻译： 本发明的各种实施方案提供了识别和编码INTSIG的人细胞内信号分子（INTSIG）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与INTSIG的异常表达相关的病症的方法。