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公开(公告)号：EP1390396A2
公开(公告)日：2004-02-25
申请号：EP02749524.1
申请日：2002-04-25
发明人： LAL, Preeti, G. , YUE, Henry , LU, Yan , YAO, Monique, G. , BECHA, Shanya, D. , BURFORD, Neil , BAUGHN, Mariah, R. , TANG, Y., Tom , BOROWSKY, Mark, L. , ELLIOTT, Vicki, S. , CHAWLA, Narinder, K. , LEE, Sally , YANG, Junming , EMERLING, Brooke, M. , NGUYEN, Danniel, B. , JACKSON, Jennifer L. , KHAN, Farrah, A. , HAFALIA, April, J., A. , ISON, Craig, H. , XU, Yuming , RICHARDSON, Thomas W. , FORSYTHE, Ian J. , SWARNAKAR, Anita , WARREN, Bridget A. , DING, Li , ZEBARJADIAN, Yeganeh , LEE, Soo Yeun , HONCHELL, Cynthia D. , THANGAVELU, Kavitha , DUGGAN, Brendan M. , TRAN, Uyen K. , GRAUL, Richard C. , POLICKY, Jennifer L. , LIANG, Shoudan , PETERSON, David P. , COCKS, Benjamin G. , SANJANWALA, Bharati , BANDMAN, Olga , HAWKINS, Phillip R. , BELL, Barrie D. , GORVAD, Ann E.
IPC分类号： C07K14/00
摘要： The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
摘要翻译： 本发明提供了用于疾病检测和治疗的人分子（MDDT）和鉴定和编码MDDT的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与MDDT异常表达相关的病症的方法。
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公开(公告)号：EP1481081A2
公开(公告)日：2004-12-01
申请号：EP02736944.6
申请日：2002-05-17
发明人： TANG, Y., Tom , YUE, Henry , AZIMZAI, Yalda , BAUGHN, Mariah, R. , BURFORD, Neil , REDDY, Roopa , WALIA, Narinder, K. , DAS, Debopriya , NGUYEN, Danniel, B. , YAO, Monique, G. , ARVIZU, Chandra, S. , LU, Yan , GANDHI, Ameena, R. , GRIFFIN, Jennifer, A. , ELLIOTT, Vicki, S. , RAMKUMAR, Jayalaxmi , LAL, Preeti, G. , LU, Dyung Aina, M. , LEE, Ernestine, A. , LEE, Soo Yeun , YUE, Huibin , YANG, Junming , TRIBOULEY, Catherine M. , KABLE, Amy E. , SWARNAKAR, Anita
CPC分类号： C07K14/4702 , A61K38/00 , C12N9/20
摘要： The invention provides human lipid-associated molecules (LIPAM) and polynucleotides which identify and encode LIPAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPAM.
摘要翻译： 本发明提供了鉴定和编码LIPAM的人类脂质相关分子（LIPAM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与LIPAM异常表达相关的病症的方法。
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公开(公告)号：EP1429806A2
公开(公告)日：2004-06-23
申请号：EP02761511.1
申请日：2002-08-22
发明人： DUGGAN, Brendan, M. , LEE, Sally , BAUGHN, Mariah, R. , HAFALIA, April, J.A. , CHAWLA, Narinder, K. , ELLIOTT, Vicki, S. , LEE, Soo, Yeun , KHARE, Reena , WILSON, Amy, D. , JIN, Pei , HAWKINS, Phillip, R. , TANG, Y., Tom , BURFORD, Neil , DING, Li , YAO, Monique, G. , BECHA, Shanya, D. , TRAN, Uyen, K. , CHIEN, David , ZEBARJADIAN, Yeganeh , RICHARDSON, Thomas W. , KABLE, Amy E. , CHANG, Hsin-Ru , SWARNAKAR, Anita , LEHR-MASON, Patricia M. , RAMKUMAR, Jayalaxmi
CPC分类号： C07K14/47
摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译： 本发明的各种实施方案提供了鉴定和编码EXMES的人细胞外信使（EXMES）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与EXMES的异常表达相关的病症的方法。
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公开(公告)号：EP1379654A2
公开(公告)日：2004-01-14
申请号：EP02713563.1
申请日：2002-02-07
发明人： DING, Li , WARREN, Bridge, A. , ELLIOTT, Vicki, S. , TANG, Y., Tom , YUE, Henry , BURFORD, Neil , LEE, Sally , RICHARDSON, Thomas, W. , LAL, Preeti , NGUYEN, Danniel, B. , YANG, Junming , HAFALIA, April, J., A. , ISON, Craig, H. , GURURAJAN, Rajagopal , BAUGHN, Mariah, R. , WANG, Yumei, E. , YAO, Monique, G. , THANGAVELU, Kavitha , SWARNAKAR, Anita , GRIFFIN, Jennifer, A. , FORSYTHE, Ian, J. , EMERLING, Brooke, M. , CHAWLA, Narinder, K.
IPC分类号： C12N15/12
CPC分类号： C07K14/47 , A01K2217/05
摘要： The invention provides human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INSTSIG.
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公开(公告)号：EP1320548A2
公开(公告)日：2003-06-25
申请号：EP01939490.7
申请日：2001-05-25
发明人： THORNTON, Michael , CHAWLA, Narinder, K , YUE, Henry , NGUYEN, Danniel, B , LAI, Preeti , GANDHI, Ameena, R , TRIBOULEY, Catherine, M , YAO, Monique, G , RAMKUMAR, Jayalaxmi , AU-YOUNG, Janice , LU, Yan , TANG, Y., Tom , AZIMZAI, Yalda , BRUNS, Christopher M., , GRIFFIN, Jennifer, A , YANG, Junming , SANJANWALA, Madhu, S , RAUMANN, Brigitte, E , LEE, Ernestine, A , HAFALIA, April , BAUGHN, Mariah, R , GREEN, Barrie, D , KHAN, Farrah, A , KEARNEY, Liam , ELLIOT, Vicki, S , SEILHAMER, Jeffrey, J , POLICKY, Jennifer, L , BOROWSKY, Mark, L , BURFORD, Neil , DING, Li , LU, Dyung, Aina, M , JACKSON, Jennifer, L
IPC分类号： C07K14/705
CPC分类号： C07K14/47
摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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公开(公告)号：EP1299412A2
公开(公告)日：2003-04-09
申请号：EP01948844.4
申请日：2001-06-29
发明人： YUE, Henry , LAL, Preeti , TANG, Y., Tom , LU, Dyung, Aina, M. , YAO, Monique, G. , NGUYEN, Danniel, B. , HAFALIA, April, J., A. , ARVIZU, Chandra, S., , DELEGEANE, Angelo, M. , BURFORD, Neil , POLICKY, Jennifer, L. , GANDHI, Ameena, R. , RAMKUMAR, Jayalaxmi , KHAN, Farrah, A. , THANGAVELU, Kavitha , XU, Yuming , GIETZEN, Kimberly, J. , CHAWLA, Narinder, K., , LU, Yan
IPC分类号： C07K14/00
CPC分类号： C07K14/47
摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMM.
摘要翻译： 本发明提供了识别和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明提供了用于诊断，治疗或预防与PMM异常表达相关的病症的方法。
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公开(公告)号：EP1297150A2
公开(公告)日：2003-04-02
申请号：EP01928748.1
申请日：2001-04-20
发明人： YUE, Henry , GANDHI, Ameena, R. , TRIBOULEY, Catherine, M. , KEARNEY, Liam , GRIFFIN, Jennifer, A. , NGUYEN, Danniel, B. , BANDMAN, Olga , LU, Dyung, Aina, M. , LAL, Preeti , BURFORD, Neil , KHAN, Farrah, A. , WALIA, Narinder, K. , YAO, Monique, G. , PATTERSON, Chandra , BURRILL, John, D. , MARCUS, Gregory, A. , ZINGLER, Kurt, A. , RECIPON, Shirley, A. , LU, Yan , POLICKY, Jennifer, L. , THORNTON, Michael , TANG, Y., Tom , HAFALIA, April , ELLIOTT, Vicki, S. , BAUGHN, Mariah, R. , WALSH, Roderick, T. , RAMKUMAR, Jayalaxmi , BOROWSKY, Mark, L. , AU-YOUNG, Janice , HILLMAN, Jennifer, L. , GURURAJAN, Rajagopal
CPC分类号： C12N9/12 , A01K2217/05 , A61K38/00
摘要： The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
摘要翻译： 本发明提供了识别和编码PKIN的人类激酶（PKIN）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PKIN异常表达相关的病症的方法。
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公开(公告)号：EP1283886A2
公开(公告)日：2003-02-19
申请号：EP01942108.0
申请日：2001-06-07
发明人： YUE, Henry , HE, Ann , NGUYEN, Danniel, B. , YAO, Monique, G. , BANDMAN, Olga , BURFORD, Neil , TANG, Y., Tom , XU, Yuming , HAFALIA, April , AZIMZAI, Yalda , WALIA, Narinder, K.
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , C12Q1/68 , A61K38/17 , A01K67/027 , G01N33/50 , G01N33/577
摘要： The invention provides human intracellular signaling proteins (ISIGP) and polynucleotides which identify and encode ISIGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ISIGP.
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公开(公告)号：EP1278843A2
公开(公告)日：2003-01-29
申请号：EP01930939.2
申请日：2001-04-27
发明人： LAL, Preeti , YUE, Henry , TANG, Y, Tom , LU, Dyung, Aina, M. , AZIMZAI, Yalda , AU-YOUNG, Janice , HILLMAN, Jennifer, L. , BAUGHN, Mariah, R. , YAO, Monique, G. , BURFORD, Neil , BATRA, Sajeev , POLICKY, Jennifer, J.
摘要： The invention provides human RNA metabolism proteins (RMEP) and polynucleotides which identify and encode RMEP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of RMEP.
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公开(公告)号：EP1266012A2
公开(公告)日：2002-12-18
申请号：EP01920431.2
申请日：2001-03-16
发明人： YUE, Henry , LU, Dyung, Aina, M. , POLICKY, Jennifer, L. , DELEGEANE, Angelo, M. , TRIBOULEY, Catherine, M. , KHAN, Farrah, A. , AU-YOUNG, Janice , BANDMAN, Olga , LAL, Preeti , BOROWSKY, Mark, L. , GANDHI, Ameena, R. , HILLMAN, Jennifer, L. , TANG, Y., Tom , BURFORD, Neil , BAUGHN, Mariah, R. , NGUYEN, Danniel, B. , YAO, Monique, G. , WALIA, Narinder, K. , HE, Ann , LU, Yan , PATTERSON, Chandra
IPC分类号： C12N15/57 , C12N9/64 , C12N9/48 , C12N1/21 , C12N5/10 , A01K67/027 , C12N15/00 , C07K16/40 , C12Q1/68 , A61K38/48 , C12Q1/37
CPC分类号： C12N9/48 , A01K2217/05 , A61K38/00 , C12N9/6421
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
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