公开(公告)号：EP1390396A2

公开(公告)日：2004-02-25

申请号：EP02749524.1

申请日：2002-04-25

申请人： Incyte Genomics, Inc. ,  Gietzen, Kimberly J.

发明人： LAL, Preeti, G. ,  YUE, Henry ,  LU, Yan ,  YAO, Monique, G. ,  BECHA, Shanya, D. ,  BURFORD, Neil ,  BAUGHN, Mariah, R. ,  TANG, Y., Tom ,  BOROWSKY, Mark, L. ,  ELLIOTT, Vicki, S. ,  CHAWLA, Narinder, K. ,  LEE, Sally ,  YANG, Junming ,  EMERLING, Brooke, M. ,  NGUYEN, Danniel, B. ,  JACKSON, Jennifer L. ,  KHAN, Farrah, A. ,  HAFALIA, April, J., A. ,  ISON, Craig, H. ,  XU, Yuming ,  RICHARDSON, Thomas W. ,  FORSYTHE, Ian J. ,  SWARNAKAR, Anita ,  WARREN, Bridget A. ,  DING, Li ,  ZEBARJADIAN, Yeganeh ,  LEE, Soo Yeun ,  HONCHELL, Cynthia D. ,  THANGAVELU, Kavitha ,  DUGGAN, Brendan M. ,  TRAN, Uyen K. ,  GRAUL, Richard C. ,  POLICKY, Jennifer L. ,  LIANG, Shoudan ,  PETERSON, David P. ,  COCKS, Benjamin G. ,  SANJANWALA, Bharati ,  BANDMAN, Olga ,  HAWKINS, Phillip R. ,  BELL, Barrie D. ,  GORVAD, Ann E.

IPC分类号： C07K14/00

摘要： The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

摘要翻译： 本发明提供了用于疾病检测和治疗的人分子（MDDT）和鉴定和编码MDDT的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与MDDT异常表达相关的病症的方法。

公开(公告)号：EP1485474A2

公开(公告)日：2004-12-15

申请号：EP02795774.5

申请日：2002-12-06

申请人： Incyte Genomics, Inc.

发明人： KABLE, Amy, E. ,  CHIEN, David ,  WILSON, Amy, D. ,  SWARNAKAR, Anita ,  GORVAD, Ann, E. ,  HAFALIA, April, J., A. ,  EMERLING, Brooke, M. ,  RAMKUMAR, Jayalaxmi ,  JIN, Pei ,  GRIFFIN, Jennifer, A. ,  MARQUIS, Joseph, P. ,  BAUGHN, Mariah, R. ,  CHAWLA, Narinder, K. ,  LEHR-MASON, Patricia, M. ,  KHARE, Reena ,  LEE, Sally ,  HAWKINS, Phillip, R. ,  BECHA, Shanya, D. ,  LEE, Soo, Yeun ,  ZEBARJADIAN, Yeganeh

IPC分类号： C12N9/16 ,  A61K38/00 ,  A61K38/46

CPC分类号： C12N9/1205 ,  C12N9/16

摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

公开(公告)号：EP1429806A2

公开(公告)日：2004-06-23

申请号：EP02761511.1

申请日：2002-08-22

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  LEE, Sally ,  BAUGHN, Mariah, R. ,  HAFALIA, April, J.A. ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  LEE, Soo, Yeun ,  KHARE, Reena ,  WILSON, Amy, D. ,  JIN, Pei ,  HAWKINS, Phillip, R. ,  TANG, Y., Tom ,  BURFORD, Neil ,  DING, Li ,  YAO, Monique, G. ,  BECHA, Shanya, D. ,  TRAN, Uyen, K. ,  CHIEN, David ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas W. ,  KABLE, Amy E. ,  CHANG, Hsin-Ru ,  SWARNAKAR, Anita ,  LEHR-MASON, Patricia M. ,  RAMKUMAR, Jayalaxmi

IPC分类号： A61K45/00 ,  C07K14/00 ,  C12P21/04

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码EXMES的人细胞外信使（EXMES）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与EXMES的异常表达相关的病症的方法。

公开(公告)号：EP1409677A2

公开(公告)日：2004-04-21

申请号：EP02709076.0

申请日：2002-01-16

申请人： Incyte Genomics, Inc.

发明人： LEE, Ernestine, A. ,  CHAWLA, Narinder, K. ,  BAUGHN, Mariah, R. ,  AZIMZAI, Yalda ,  TANG, Y., Tom ,  YUE, Henry ,  THANGAVELU, Kavitha ,  XU, Yuming ,  ARVIZU, Chandra ,  WARREN, Bridget, A. ,  YAO, Monique, G. ,  AU-YOUNG, Janice ,  HAFALIA, April, J., A. ,  ELLIOTT, Vicki, S. ,  KALLICK, Deborah, A. ,  GANDHI, Ameena, R. ,  RICHARDSON, Thomas, W. ,  KHAN, Farrah, A. ,  LU, Yan ,  SWARNAKAR, Anita ,  RAMKUMAR, Jayalaxmi ,  NGUYEN, Danniel B. ,  GRAUL, Richard C. ,  LU, Dyung Aina M.

IPC分类号： C12N15/12 ,  C07K14/705 ,  C12N5/10 ,  A01K67/027 ,  C07K16/28 ,  C12Q1/68 ,  A61K38/17 ,  G01N33/68 ,  A61K39/395

CPC分类号： C07K14/705 ,  A61K38/00

摘要： The invention provides human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.

公开(公告)号：EP1409550A1

公开(公告)日：2004-04-21

申请号：EP02739996.3

申请日：2002-06-26

申请人： Incyte Genomics, Inc.

发明人： DELEGEANE, Angelo, M. ,  BOROWSKY, Mark, L. ,  KHAN, Farrah, A. ,  KEARNEY, Liam ,  RAMKUMAR, Jayalaxmi ,  CHAWLA, Narinder, K. ,  LU, Yan ,  HONCHELL, Cynthia, D. ,  KALLICK, Deborah, A. ,  EMERLING, Brooke, M. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  WARREN, Bridget, A. ,  YUE, Henry ,  THANGAVELU, Kavitha ,  SPRAGUE, William, W. ,  ISON, Craig, H. ,  ELLIOTT, Vicki, S. ,  MASON, Patricia, M. ,  RICHARDSON, Thomas W. ,  TRAN, Uyen K. ,  SWARNAKAR, Anita ,  JIN, Pei ,  KABLE, Amy E.

IPC分类号： C07K17/00

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.

公开(公告)号：EP1379654A2

公开(公告)日：2004-01-14

申请号：EP02713563.1

申请日：2002-02-07

申请人： Incyte Genomics, Inc.

发明人： DING, Li ,  WARREN, Bridge, A. ,  ELLIOTT, Vicki, S. ,  TANG, Y., Tom ,  YUE, Henry ,  BURFORD, Neil ,  LEE, Sally ,  RICHARDSON, Thomas, W. ,  LAL, Preeti ,  NGUYEN, Danniel, B. ,  YANG, Junming ,  HAFALIA, April, J., A. ,  ISON, Craig, H. ,  GURURAJAN, Rajagopal ,  BAUGHN, Mariah, R. ,  WANG, Yumei, E. ,  YAO, Monique, G. ,  THANGAVELU, Kavitha ,  SWARNAKAR, Anita ,  GRIFFIN, Jennifer, A. ,  FORSYTHE, Ian, J. ,  EMERLING, Brooke, M. ,  CHAWLA, Narinder, K.

IPC分类号： C12N15/12

CPC分类号： C07K14/47 ,  A01K2217/05

摘要： The invention provides human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INSTSIG.

公开(公告)号：EP1368473A2

公开(公告)日：2003-12-10

申请号：EP02718986.9

申请日：2002-02-15

申请人： Incyte Genomics, Inc.

发明人： DUGGAN, Brendan, M. ,  HONCHELL, Cynthia, D. ,  ISON, Craig, H. ,  THANGAVELU, Kavitha ,  LU, Dyung Aina, M. ,  BAUGHN, Mariah, R. ,  LAL, Preeti, G. ,  YUE, Henry ,  TANG, Y., Tom ,  WARREN, Bridget, A. ,  LEE, Ernestine, A. ,  GRIFFIN, Jennifer, A. ,  FORSYTHE, Ian, J. ,  CHAWLA, Narinder, K. ,  JIANG, Xin ,  JACKSON, Alan, A.

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K16/28 ,  A01K67/027 ,  C12Q1/68 ,  G01N33/577 ,  G01N33/68 ,  A61K38/17 ,  A61K39/395 ,  A61P25/00

CPC分类号： C07K14/705 ,  A01K2217/05 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.

公开(公告)号：EP1297014A2

公开(公告)日：2003-04-02

申请号：EP01952302.6

申请日：2001-06-27

申请人： Incyte Genomics, Inc.

发明人： RAUMANN, Brigitte, E. ,  SANJANWALA, Madhu, S. ,  TRIBOULEY, Catherine, M. ,  CHAWLA, Narinder, K.

IPC分类号： C07K14/705

CPC分类号： C07K14/47

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or prevention disorders associated with aberrant expression of TRICH.

摘要翻译： 本发明提供了识别和编码TRICH的人转运蛋白和离子通道（TRICH）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与TRICH的异常表达相关的病症的方法。

公开(公告)号：EP1521822A2

公开(公告)日：2005-04-13

申请号：EP02773383.1

申请日：2002-09-13

申请人： Incyte Genomics, Inc.

发明人： SPRAGUE, William, W. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  TANG, Y., Tom ,  ELLIOTT, Vicki, S. ,  MARQUIS, Joseph, P. ,  LI, Joana, X. ,  GRIFFIN, Jennifer, A. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  LU, Dyung Aina, M. ,  EMERLING, Brooke, M. ,  DUGGAN, Brendan, M. ,  RICHARDSON, Thomas, W. ,  LEE, Soo, Yeun ,  RAMKUMAR, Jayalaxmi ,  BECHA, Shanya, D. ,  LEHR-MASON, Patricia, M. ,  SWARNAKAR, Anita ,  TRAN, Uyen K. ,  KABLE, Amy E. ,  HAFALIA, April J.A. ,  KHARE, Reena

IPC分类号： C12N9/00 ,  C07H21/04

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12N9/6421

摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.

公开(公告)号：EP1497315A2

公开(公告)日：2005-01-19

申请号：EP02793861.2

申请日：2002-10-29

申请人： Incyte Genomics, Inc.

发明人： BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  BURFORD, Neil ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J., A. ,  ISON, Craig, H. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Sally ,  LEE, Soo, Yeun ,  MARQUIS, Joseph, P. ,  RAMKUMAR, Jayalaxmi ,  SPRAGUE, William, W. ,  SWARNAKAR, Anita ,  WARREN, Bridget, A. ,  TANG, Y. Tom ,  YANG, Yunming ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh

IPC分类号： C07K5/00

CPC分类号： C07K14/47 ,  G01N33/6875 ,  G01N2500/04

摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.