公开(公告)号：EP1390396A2

公开(公告)日：2004-02-25

申请号：EP02749524.1

申请日：2002-04-25

申请人： Incyte Genomics, Inc. ,  Gietzen, Kimberly J.

发明人： LAL, Preeti, G. ,  YUE, Henry ,  LU, Yan ,  YAO, Monique, G. ,  BECHA, Shanya, D. ,  BURFORD, Neil ,  BAUGHN, Mariah, R. ,  TANG, Y., Tom ,  BOROWSKY, Mark, L. ,  ELLIOTT, Vicki, S. ,  CHAWLA, Narinder, K. ,  LEE, Sally ,  YANG, Junming ,  EMERLING, Brooke, M. ,  NGUYEN, Danniel, B. ,  JACKSON, Jennifer L. ,  KHAN, Farrah, A. ,  HAFALIA, April, J., A. ,  ISON, Craig, H. ,  XU, Yuming ,  RICHARDSON, Thomas W. ,  FORSYTHE, Ian J. ,  SWARNAKAR, Anita ,  WARREN, Bridget A. ,  DING, Li ,  ZEBARJADIAN, Yeganeh ,  LEE, Soo Yeun ,  HONCHELL, Cynthia D. ,  THANGAVELU, Kavitha ,  DUGGAN, Brendan M. ,  TRAN, Uyen K. ,  GRAUL, Richard C. ,  POLICKY, Jennifer L. ,  LIANG, Shoudan ,  PETERSON, David P. ,  COCKS, Benjamin G. ,  SANJANWALA, Bharati ,  BANDMAN, Olga ,  HAWKINS, Phillip R. ,  BELL, Barrie D. ,  GORVAD, Ann E.

IPC分类号： C07K14/00

摘要： The invention provides human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

摘要翻译： 本发明提供了用于疾病检测和治疗的人分子（MDDT）和鉴定和编码MDDT的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与MDDT异常表达相关的病症的方法。

公开(公告)号：EP1578899A2

公开(公告)日：2005-09-28

申请号：EP02731905.2

申请日：2002-05-21

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LEE, Ernestine, A. ,  BECHA, Shanya, D. ,  BAUGHN, Mariah, R. ,  YAO, Monique, G. ,  TANG, Y., Tom ,  AU-YOUNG, Janice, K. ,  LAL, Preeti, G. ,  WARREN, Bridget, A. ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  XU, Yuming ,  THANGAVELU, Kavitha ,  RICHARDSON, Thomas, W. ,  BANDMAN, Olga ,  JONES, Karen, Anne ,  YANG, Junming ,  EMERLING, Brooke, M. ,  SWARNAKAR, Anita ,  LUO, Wen ,  CHAWLA, Narinder K. ,  AZIMZAI, Yalda ,  KHAN, Farrah A. ,  LU, Dyung Aina M. ,  GRIFFIN, Jennifer A. ,  LEE, Soo Yeun ,  BURFORD, Neil ,  ELLIOTT, Vicki S. ,  HONCHELL, Cynthia D. ,  HE, Ann ,  MASON, Patricia M. ,  LI, Joana X. ,  HAFALIA, April J.A. ,  GURURAJAN, Rajagopal

IPC分类号： C12N1/00

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human secreted proteins (SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

公开(公告)号：EP1521824A2

公开(公告)日：2005-04-13

申请号：EP02728471.0

申请日：2002-03-14

申请人： Incyte Genomics, Inc.

发明人： JACKSON, Jennifer, L. ,  BAUGHN, Mariah, R. ,  SWARNAKAR, Anita ,  YUE, Henry ,  ELLIOTT, Vicki, S. ,  BURFORD, Neil ,  DING, Li ,  TANG, Y., Tom ,  LEE, Soo, Yeun ,  AZIMZAI, Yalda ,  CHAWLA, Narinder, K. ,  GIETZEN, Kimberly, J. ,  GRIFFIN, Jennifer, A. ,  LAL, Preeti, G. ,  YANG, Junming ,  BOROWSKY, Mark, L. ,  RICHARDSON, Thomas, W. ,  YUE, Huibin ,  BECHA, Shanya ,  FORSYTHE, Ian J. ,  JONES, Karen Anne ,  WARREN, Bridget A. ,  THANGAVELU, Kavitha ,  HONCHELL, Cynthia D. ,  JOLLEY, Helen E. ,  HAFALIA, April J.A. ,  RING, Huijun Z.

IPC分类号： C12N9/10 ,  C12N15/54 ,  C12N15/70 ,  C12N15/79 ,  A61K38/45

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00

摘要： The invention provides human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

公开(公告)号：EP1478745A2

公开(公告)日：2004-11-24

申请号：EP02731940.9

申请日：2002-05-23

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LU, Dyung Aina, M. ,  AZIMZAI, Yalda ,  DING, Li ,  LEE, Ernestine, A. ,  HAFALIA, April, J., A. ,  BECHA, Shanya, D. ,  TANG, Y., Tom ,  LAL, Preeti, G. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  RAMKUMAR, Jayalaxmi ,  ELLIOTT, Vicki, S. ,  ARVIZU, Chandra, S. ,  LUO, Wen ,  SWARNAKAR, Anita ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  GANDHI, Ameena R. ,  YAO, Monique G. ,  KHAN, Farrah A. ,  BAUGHN, Mariah R. ,  BOROWSKY, Mark L. ,  ZEBARJADIAN, Yeganeh ,  RICHARDSON, Thomas W. ,  MARQUIS, Joseph P. ,  CHIEN, David ,  JIN, Pei

IPC分类号： C12N9/20 ,  C12N9/14 ,  C12N15/00 ,  C12N5/00 ,  C12N1/20 ,  C07K1/00 ,  C07H21/04 ,  C07H21/02 ,  C12Q1/68

CPC分类号： C12N9/1205 ,  C12N9/16

摘要： The invention provides human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明提供了识别和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1442064A2

公开(公告)日：2004-08-04

申请号：EP02801802.6

申请日：2002-10-17

申请人： Incyte Genomics, Inc.

发明人： BANDMAN, Olga ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  DUGGAN, Brendan, M. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GANDHI, Ameena, R. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  HAFALIA, April, J.A. ,  KHAN, Farrah, A. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Soo, Yeun ,  LINDQUIST, Erika, A. ,  LU, Dyung Aina, M. ,  LU, Yan ,  MARQUIS, Joseph, P. ,  NGUYEN, Danniel, B. ,  ARVIZU, Chandra S. ,  RAMUKAR, Jayalaxmi ,  RECIPON, Shirley A. ,  RICHARDSON, Thomas, W. ,  SWARNAKAR, Anita ,  TANG, Y., Tom ,  THORNTON, Michael ,  TRAN, Uyen, K. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget A. ,  YANG, Junming ,  YAO, Monique G. ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh

IPC分类号： C07K16/00 ,  A61K38/00

CPC分类号： C12N9/1205 ,  A01K2217/05

摘要： Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码KPP的人类激酶和磷酸酶（KPP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与KPP异常表达相关的病症的方法。

公开(公告)号：EP1430129A2

公开(公告)日：2004-06-23

申请号：EP02713385.9

申请日：2002-01-08

申请人： Incyte Genomics, Inc.

发明人： REDDY, Roopa ,  TANG, Y., Tom ,  BAUGHN, Mariah, R. ,  KRASNOW, Randi

IPC分类号： C12N15/12 ,  C07K14/47 ,  A61K31/7088 ,  C12Q1/68 ,  C12N5/10 ,  A61K38/17 ,  C07K16/18 ,  G01N33/68 ,  A61K39/395

CPC分类号： C07K14/47 ,  A61K38/00 ,  C12N2799/026

摘要： The invention provides cDNAs which encode ASIP-related proteins. It also provides for the use of the cDNAs, fragments, complements, and variants thereof and of the encoded proteins, portions thereof and antibodies thereto for diagnosis and treatment of cancer, particularly bladder transitional cell carcinoma. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.

公开(公告)号：EP1412387A2

公开(公告)日：2004-04-28

申请号：EP01988245.5

申请日：2001-10-25

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  YUE, Henry ,  NGUYEN, Danniel, B. ,  HAFALIA, April, J., A. ,  ELLIOTT, Vicki, S. ,  LU, Yan ,  CHAWLA, Narinder, K. ,  YAO, Monique, G. ,  BAUGHN, Mariah, R. ,  GANDHI, Ameena, R. ,  DING, Li ,  SANJANWALA, Madhusudan ,  RAMKUMAR, Jayalaxmi ,  ARVIZU, Chandra ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  AZIMZAI, Yalda ,  KHAN, Farrah, A. ,  THANGAVELU, Kavitha ,  THORNTON, Michael ,  LU, Dyung Aina M. ,  TRIBOULEY, Catherine M. ,  WARREN, Bridget A. ,  ISON, Craig H. ,  DAS, Debopriya ,  RAUMANN, Brigitte E. ,  POLICKY, Jennifer L. ,  KEARNEY, Liam

IPC分类号： C07K14/705

CPC分类号： C07K14/705

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

公开(公告)号：EP1368472A2

公开(公告)日：2003-12-10

申请号：EP02704382.7

申请日：2002-02-08

申请人： Incyte Genomics, Inc.

发明人： LAL, Preeti, G. ,  BAUGHN, Mariah, R. ,  YAO, Monique, G. ,  CHAWLA, Narinder, K. ,  ELLIOT, Vicki, S. ,  XU, Yuming ,  HONCHELL, Cynthia, D. ,  YUE, Henry ,  DING, Li ,  GIETZEN, Kimberly, J. ,  ISON, Craig, H. ,  LU, Dyung, Aina, M. ,  HAFALIA, April, J., A. ,  GANDHI, Ameena, R. ,  THANGAVELU, Kavitha ,  SANJANWALA, Madhusudan, M. ,  TANG, Y., Tom ,  RAMKUMAR, Jayalaxmi ,  GRIFFIN, Jennifer, A. ,  SWARNAKAR, Anita ,  AZIMZAI, Yalda ,  KAREHT, Stephanie K. ,  BURFORD, Neil ,  LEE, Ernestine A. ,  LU, Yan ,  TRAN, Uyen K. ,  MARQUIS, Joseph P.

IPC分类号： C12N15/12 ,  C12N5/10 ,  C12Q1/68 ,  C07K14/47 ,  C07K16/18 ,  G01N33/50 ,  G01N33/68 ,  A01K67/027 ,  A61K38/17 ,  A61K39/395

CPC分类号： C12N9/6421 ,  A61K38/00 ,  C07K14/47

摘要： The invention provides full-length human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1366165A2

公开(公告)日：2003-12-03

申请号：EP02718924.0

申请日：2002-02-06

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  TRIBOULEY, Catherine, M. ,  NGUYEN, Danniel, B. ,  THORNTON, Michael ,  YAO, Monique, G. ,  KALLICK, Deborah, A. ,  GANDHI, Ameena, R. ,  CHAWLA, Narinder, K. ,  ARVIZU, Chandra ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J., A. ,  RAMKUMAR, Jayalaxmi ,  PEI, Jin ,  TANG, Y., Tom ,  YUE, Henry ,  REDDY, Roopa, M. ,  BURFORD, Neil ,  LU, Dyung, Aina, M. ,  GRAUL, Richard, C. ,  KHAN, Farrah A. ,  WALSH, Roderick T. ,  ISON, Craig H. ,  RICHARDSON, Thomas W. ,  GRIFFIN, Jennifer A. ,  WARREN, Bridget A. ,  YANG, Junming ,  LEE, Ernestine A. ,  HARLAND, Lee

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K14/72 ,  C12N5/10 ,  C07K16/28 ,  C12Q1/68 ,  A61K38/16 ,  G01N33/50 ,  A61K31/00 ,  A61K33/00 ,  A61K39/395

CPC分类号： C07K14/723 ,  C07K14/705

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

公开(公告)号：EP1358323A2

公开(公告)日：2003-11-05

申请号：EP01941734.4

申请日：2001-05-30

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  AZIMZAI, Yalda ,  YUE, Henry ,  BURFORD, Neil ,  DING, Li ,  ELLIOTT, Vicki, S. ,  ARVIZU, Chandra ,  BAUGHN, Mariah, R.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/18 ,  G01N33/68 ,  G01N33/53 ,  A61K38/17 ,  C12Q1/68

CPC分类号： C07K16/18 ,  A61K38/00 ,  C07K14/4747 ,  C12Q1/6876

摘要： The invention provides human apoptosis regulators (APRG) and polynucleotides which identify and encode APRG. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of APRG.