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    METHOD FOR SYNTHESIZING PROTEIN CONTAINING HIGH CONTENT OF SPECIFIC AMINO ACID THROUGH SIMULTANEOUS EXPRESSION WITH TRNA OF THE SPECIFIC AMINO ACID
    3.
    发明公开
    METHOD FOR SYNTHESIZING PROTEIN CONTAINING HIGH CONTENT OF SPECIFIC AMINO ACID THROUGH SIMULTANEOUS EXPRESSION WITH TRNA OF THE SPECIFIC AMINO ACID 有权
    合成与特定的氨基比例较高的蛋白质BY同时表达与特定的tRNA氨基方法

    公开(公告)号：EP2330186A2

    公开(公告)日：2011-06-08

    申请号：EP09814823.2

    申请日：2009-09-22

    申请人： Korea Advanced Institute of Science and Technology

    发明人： LEE, Sang Yup ,  XIA, Xiaoxia ,  QIAN, Zhi Gang ,  BAEK, Jong Hwan

    IPC分类号： C12N1/21

    CPC分类号： C12N15/67 ,  C07K14/43518 ,  C07K14/43586

    摘要： The present invention relates to a method of increasing the expression of a target protein by co-expression of a gene encoding a target protein having a high content of a specific amino acid with a nucleotide sequence encoding the tRNA of the specific amino acid. According to the present invention, the expression of a protein having a high content of a specific amino acid can be remarkably increased by co-expression with the tRNA of the specific amino acid. Thus, the present invention is useful for increasing the productivity of a protein having a high content of a specific amino acid, such as a repetitive protein.

    摘要翻译： 本发明涉及由编码具有特定氨基酸的用编码特定氨基酸的tRNA的核苷酸序列的含量高的靶蛋白的基因的共表达增加靶蛋白的表达的方法。 。根据本发明，具有特定氨基酸的含量高的蛋白的表达可显着通过与特定的氨基酸的tRNA的联合表达增加。 因此，本发明是一种用于提高具有特定氨基酸的含量高，检查作为重复蛋白的蛋白质的生产率是有用的。

    HIGH MOLECULAR WEIGHT RECOMBINANT SILK OR SILK-LIKE PROTEIN, AND MICRO- OR NANOSCALE SPIDER-WEB FIBER OR SPIDER-WEB-LIKE FIBER PRODUCED USING THE RECOMBINANT SILK OR SILK-LIKE PROTEIN
    5.
    发明公开
    HIGH MOLECULAR WEIGHT RECOMBINANT SILK OR SILK-LIKE PROTEIN, AND MICRO- OR NANOSCALE SPIDER-WEB FIBER OR SPIDER-WEB-LIKE FIBER PRODUCED USING THE RECOMBINANT SILK OR SILK-LIKE PROTEIN 审中-公开
    重组丝蛋白或组织样蛋白由高分子量，并从重组丝蛋白或像蛋白生产或超细纤维纳米级蜘蛛网和蜘蛛网状纤维

    公开(公告)号：EP2546263A2

    公开(公告)日：2013-01-16

    申请号：EP11713459.3

    申请日：2011-03-11

    申请人： Korea Advanced Institute of Science and Technology

    发明人： LEE, Sang Yup ,  XIA, Xiaoxia ,  QIAN, Zhi Gang ,  LEE, Jeong Wook ,  PARK, Young Hwan

    IPC分类号： C07K14/435 ,  C12N15/12 ,  C12N15/63 ,  D01F4/00

    CPC分类号： C07K14/43518 ,  D01D5/0007 ,  D01D5/06 ,  D01F4/02

    摘要： The present invention relates to a high-molecular-weight recombinant silk or silk-like protein having a molecular weight which is substantially similar to that of native silk protein, and to a micro- or nano-sized spider silk or silk-like fiber having improved physical properties, produced therefrom. The recombinant silk or silk-like protein according to the invention has high molecular weight, like dragline silk proteins from spiders, while a fiber produced therefrom has excellent physical properties compared to a fiber produced from native silk protein. Thus, the recombinant silk or silk-like protein and the spider silk or silk-like fiber produced therefrom will be highly useful in various industrial applications, including bioengineering applications and medical applications.

    摘要翻译： 本发明涉及一种高分子量的重组丝或丝样蛋白质基本上所有的分子量，其类似于做天然丝蛋白的，并以微米或纳米尺寸的蜘蛛丝或丝状纤维具有 改进的物理性能，从那里产生的。 重组丝或丝样蛋白gemäß到，本发明具有高的分子量，例如从蜘蛛拖丝蛋白质，而纤维产生有从具有优异的物理性能相比于从天然丝蛋白生产的纤维。 因此，重组丝或丝样蛋白和蜘蛛丝或由其产生丝状纤维将是在各种工业应用中，包括生物工程应用和医疗应用中非常有用的。

    MUTANT MICROORGANISM WITH HIGH ABILITY OF PRODUCING PUTRESCINE AND PREPARATION OF PUTRESCINE USING SAME
    6.
    发明公开
    MUTANT MICROORGANISM WITH HIGH ABILITY OF PRODUCING PUTRESCINE AND PREPARATION OF PUTRESCINE USING SAME 有权
    MUTIERTER MIKROORGANISMUS MIT HOHEM PUTRESCIN-PRODUKTIONSVERMÖGENUND HERSTELLUNG VON PUTRESCIN DAMIT

    公开(公告)号：EP2281880A2

    公开(公告)日：2011-02-09

    申请号：EP09729276.7

    申请日：2009-03-05

    申请人： Korea Advanced Institute of Science and Technology

    发明人： LEE, Sang Yup ,  QIAN, Zhi Gang ,  XIA, Xiaoxia ,  JEON, Yong Jae

    IPC分类号： C12N15/00

    CPC分类号： C12P13/001

    摘要： The present invention relates to mutant microorganisms having high ability to produce putrescine in which genes involved in the putrescine degradation or utilization pathway of microorganisms having a putrescine-producing metabolic pathway are inactivated or deleted; and a method for producing putrescine in high yield by culturing the mutant microorganisms under anaerobic conditions. The mutant microorganisms having high ability to produce putrescine are useful for producing a high yield of putrescine which is used in a wide range of industrial applications.

    摘要翻译： 本发明涉及产生腐胺的能力较强的突变微生物，其中涉及具有产生腐胺的代谢途径的微生物的腐胺降解或利用途径的基因被灭活或缺失; 以及通过在厌氧条件下培养突变体微生物，以高产率产生腐胺的方法。 具有高腐蚀能力的突变微生物对于产生广泛的工业应用的高产量的腐胺是有用的。