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公开(公告)号:EP1509263B1
公开(公告)日:2006-06-07
申请号:EP03728981.6
申请日:2003-05-15
申请人: MEDTRONIC, INC.
IPC分类号: A61M5/142
CPC分类号: A61M5/14276 , A61M5/1413
摘要: A medical device known as an implantable infusion device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spasticity, cancer, and many other conditions. The infusion device incorporates a motor coil connector and mechanical sealing system between the clean motor compartment and the potentially corrosive pump compartment that provides a reliable electrical connection between the motor coil and the motor drive electronics. The motor coil connector provides for bonding of a very small diameter coil wire to one end of the connector and a highly corrosion resistant connection at the other end of the connector. Additionally, the motor coil connector and mechanical sealing system provides a seal against harmful corrosion materials that could emanate from the pump compartment and reach the motor compartment and cause malfunction of the motor.
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公开(公告)号:EP1578495A1
公开(公告)日:2005-09-28
申请号:EP03790404.2
申请日:2003-12-09
申请人: MEDTRONIC, INC.
发明人: JANZIG, Darren, A. , WAHLSTRAND, Carl, D. , SKIME, Robert, M. , LENT, Mark, S. , MIESEL, Keith, A. , CABAK, James, E.
CPC分类号: A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要: In an implantable medical device (101, 201, 401A-F, 501, 601, 701, 801, 901) having individual modules (103-105, 210-212, 410-412, 510-512, 610-611, 711-713, 811-812, 911-912, 1110-1111, 1201-1202), a coupling module (521, 612, 721, 722, 821, 921, 1001, 1101, 1222) couples the modules to one another. The coupling module supports electrical and/or mechanical coupling of the modules. The coupling module may assume a variety of shapes or configurations. The various embodiments of the coupling module may offer the modules varying degrees of freedom of movement relative to one another.
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公开(公告)号:EP1578495B1
公开(公告)日:2010-06-02
申请号:EP03790404.2
申请日:2003-12-09
申请人: Medtronic, Inc.
发明人: JANZIG, Darren, A. , WAHLSTRAND, Carl, D. , SKIME, Robert, M. , LENT, Mark, S. , MIESEL, Keith, A. , CABAK, James, E.
CPC分类号: A61N1/375 , A61N1/3605 , A61N1/3754 , A61N1/3758
摘要: In an implantable medical device (101, 201, 401A-F, 501, 601, 701, 801, 901) having individual modules (103-105, 210-212, 410-412, 510-512, 610-611, 711-713, 811-812, 911-912, 1110-1111, 1201-1202), a coupling module (521, 612, 721, 722, 821, 921, 1001, 1101, 1222) couples the modules to one another. The coupling module supports electrical and/or mechanical coupling of the modules. The coupling module may assume a variety of shapes or configurations. The various embodiments of the coupling module may offer the modules varying degrees of freedom of movement relative to one another.
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公开(公告)号:EP1385570A2
公开(公告)日:2004-02-04
申请号:EP02734124.7
申请日:2002-04-30
申请人: Medtronic, INC.
发明人: LAPORTE, Steve , HALLER, Markus , HOOPER, William, J. , LENT, Mark, S. , RIFF, Kenneth, M. , HERUTH, Kenneth, T. , OLSEN, James, M.
CPC分类号: A61N1/37235 , A61B5/0031 , A61B2560/0271 , A61M5/14216 , A61M5/14244 , A61M5/14248 , A61M5/1723 , A61M37/0092 , A61M2005/14208 , A61M2005/14268 , A61M2205/3523 , A61N1/08 , A61N1/30 , A61N1/3702 , A61N1/37217 , A61N1/37258 , A61N1/37288 , G06F19/00 , G06F19/3456 , G06F19/3481 , G16H40/63
摘要: An external physiologic or implanted device monitor/controller ("monitor") designed to be attached to the body, as for example, to the skin of the patient. The monitor is designed to detect the therapeutic outputs actually produced by the implanted medical device. Having knowledge of the operation of the implanted medical device, the monitor may then deduce, or decode, the physiologic conditions and/or devices conditions sensed by the implanted medical device. The monitor is then able to perform an action appropriate to the sensed condition and the specific implementation.
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公开(公告)号:EP1919536B1
公开(公告)日:2011-06-29
申请号:EP06788113.6
申请日:2006-07-21
申请人: Medtronic, Inc.
发明人: OLSEN, James, M. , LENT, Mark, S. , SKAKOON, James, G. , STONE, Richard, T. , MAYOR, Laetitia , SEELEY, Dale, F. , HEGLAND, Michael, T.
CPC分类号: A61M5/14593 , A61M5/14276 , A61M5/16881 , A61M39/0208 , A61M2039/0205 , A61M2205/0266
摘要: A miniature drug delivery pump utilizes a shape memory Ni-Ti alloy. A flow restrictor is provided and the pump is refillable.
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公开(公告)号:EP2318091A1
公开(公告)日:2011-05-11
申请号:EP09743106.8
申请日:2009-01-23
申请人: MEDTRONIC, INC.
发明人: KING, Gary, W. , GOETZ, Steven, M. , HOUCHINS, Andrew, H. , KEACHER, Jeffrey, T. , GREENBERG, Jordan, J. , HERUTH, Kenneth, T. , LENT, Mark, S. , WACNIK, Paul, W.
IPC分类号: A61N1/34
CPC分类号: A61N1/36139 , A61N1/36057 , A61N1/36071
摘要: Peripheral nerve field stimulation (PNFS) may be controlled based on detected physiological effects of the PNFS, which may be an efferent response to the PNFS. In some examples, a closed-loop therapy system may include a sensing module that senses a physiological parameter of the patient, which may be indicative of the patient's response to the PNFS. Based on a signal generated by the sensing module, the PNFS may be activated, deactivated or modified. Example physiological parameters of the patient include heart rate, respiratory rate, electrodermal activity, muscle activity, blood flow rate, sweat gland activity, pilomotor reflex, or thermal activity of the patient's body. In some examples, a patient pain state may be detected based on a signal generated by the sensing module, and therapy may be controlled based on the detection of the pain state.
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公开(公告)号:EP1802366B1
公开(公告)日:2008-12-10
申请号:EP05787802.7
申请日:2005-08-22
申请人: MEDTRONIC, INC.
CPC分类号: A61L31/10 , A61K9/0024 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/404 , A61L2300/406 , A61L2300/45 , A61L2300/61 , A61M37/00 , A61M2025/0057 , A61N1/0534 , A61N1/0536 , A61N1/0551 , A61N1/36071
摘要: Medical devices configured to be implanted in two or more tissues simultaneously are discussed. A therapeutic agent is disposed on, in, or about at least a portion of an external surface of a medical device configured to be placed in one tissue, but not on, in or about a surface configured to be placed in another tissue. The therapeutic agent may be disposed on or in a polymeric material, which is disposed on or about at least a portion of an external surface of first portion the medical device. Such targeted placement of polymeric material may allow for the therapeutic agent to be eluted in an appropriate tissue and may allow for decreased undesired effects.
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公开(公告)号:EP1904159B1
公开(公告)日:2012-08-22
申请号:EP06772721.4
申请日:2006-06-09
申请人: Medtronic, Inc.
IPC分类号: A61N1/34
CPC分类号: A61M5/14276 , A61M5/172 , A61M5/1723 , A61M2205/054 , A61M2205/3523 , A61N1/025 , A61N1/36071 , A61N1/372 , A61N1/37229
摘要: Systems and methods for coordinated delivery of a therapeutic agent and low (less than about 20 Hz) and high (greater than about 50 Hz)frequency stimulation therapy are described. The systems include a control unit for coordinating therapy delivery between an infusion device and a pulse generator, such that a therapeutic agent is administered at a predetermined time relative to application of either low frequency or high frequency stimulation. For example, the control unit may instruct the infusion device to deliver therapeutic agent at a predetermined time prior to delivery of low frequency stimulation. Systems that include more than one infusion device or an infusion pump capable of delivering more than one therapeutic agent are also described.
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公开(公告)号:EP2211986A1
公开(公告)日:2010-08-04
申请号:EP08838892.1
申请日:2008-09-25
申请人: MEDTRONIC, INC.
发明人: MOLNAR, Gregory, F. , GILL, Steven, S. , MIESEL, Keith, A. , LENT, Mark, S. , DENISON, Timothy, J. , PANKEN, Eric, J. , WAHLSTRAND, Carl, D. , WERDER, Jonathan, C.
CPC分类号: A61B5/04014 , A61B5/0006 , A61B5/4082 , A61B5/6814 , A61N1/36003 , A61N1/36014 , A61N1/36025 , A61N1/36067 , A61N1/36082
摘要: A movement state of a patient is detected based on brain signals, such as an electroencephalogram (EEG) signal. In some examples, a brain signal within a dorsal-lateral prefrontal cortex of a brain of the patient indicative of prospective movement of the patient may be sensed in order to detect the movement state. The movement state may include the brain state that indicates the patient is intending on initiating movement, initiating movement, attempting to initiate movement or is actually moving. In some examples, upon detecting the movement state, a movement disorder therapy is delivered to the patient. In some examples, the therapy delivery is deactivated upon detecting the patient is no longer in a movement state or that the patient has successfully initiated movement. In addition, in some examples, the movement state detected based on the brain signals may be confirmed based on a signal from a motion sensor.
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公开(公告)号:EP1919536A1
公开(公告)日:2008-05-14
申请号:EP06788113.6
申请日:2006-07-21
申请人: Medtronic Inc.
发明人: OLSEN, James, M. , LENT, Mark, S. , SKAKOON, James, G. , STONE, Richard, T. , MAYOR, Laetitia , SEELEY, Dale, F. , HEGLAND, Michael, T.
CPC分类号: A61M5/14593 , A61M5/14276 , A61M5/16881 , A61M39/0208 , A61M2039/0205 , A61M2205/0266
摘要: A miniature drug delivery pump utilizes a shape memory Ni-Ti alloy. A flow restrictor is provided and the pump is refillable.
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