公开(公告)号：EP3356817A1

公开(公告)日：2018-08-08

申请号：EP16778093.1

申请日：2016-09-22

申请人： Micromass UK Limited ,  Pringle, Steven Derek ,  Gödörházy, Lajos ,  Simon, Dániel ,  Szalay, Dániel ,  Takáts, Zoltán ,  Karancsi, Tamás

发明人： PRINGLE, Steven Derek ,  GÖDÖRHÁZY, Lajos ,  SIMON, Dániel ,  SZALAY, Dániel ,  TAKÁTS, Zoltán ,  KARANCSI, Tamás

IPC分类号： G01N33/483 ,  H01J49/04

CPC分类号： H01J49/049 ,  G01N21/31 ,  G01N21/65 ,  G01N33/4833 ,  H01J49/0445 ,  H01J49/0459

摘要： A method of analysis is disclosed comprising providing a sample on an insulating substrate such as a petri dish (4) and contacting e.g. the rear surface of the insulating substrate with a first electrode (9). The method further comprises contacting the sample with a second electrode (2) and applying an AC or RF voltage to the first and second electrodes (9,2) in order to generate an aerosol from the sample.

公开(公告)号：EP4257967A2

公开(公告)日：2023-10-11

申请号：EP23191404.5

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： SIMON, Dániel ,  GÖDÖRHÁZY, Lajos ,  SZALAY, Dániel ,  PRINGLE, Steven Derek ,  JONES, Emrys ,  TRIVETT, Ian ,  O'BRIEN, Stephen ,  HESSE, Anthony ,  HENDERSON, Matt ,  CHUA, Alvin ,  TAKÁTS, Zoltán ,  KARANCSI, Tamás

IPC分类号： G01N27/623

摘要： An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil-shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.

公开(公告)号：EP3265817B1

公开(公告)日：2020-08-12

申请号：EP16709551.2

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： TAKÁTS, Zoltán ,  JONES, Emrys ,  LANGRIDGE, James Ian ,  MORRIS, Michael Raymond ,  KARANCSI, Tamás ,  PRINGLE, Steven Derek ,  BALOG, Júlia ,  SIMON, Dániel ,  GÖDÖRHÁZY, Lajos ,  SZALAY, Dániel ,  RICHARDSON, Keith ,  BENNETT, Philip Robert ,  MACINTYRE, David Alan ,  PRUSKI, Pamela

IPC分类号： G01N33/68

公开(公告)号：EP3671216A1

公开(公告)日：2020-06-24

申请号：EP20154538.1

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： PRINGLE, Steven Derek ,  MORRIS, Michael Raymond ,  BALOG, Júlia ,  JONES, Emrys ,  RICHARDSON, Keith ,  LANGRIDGE, James Ian ,  SIMON, Dániel ,  GÖDÖRHÁZY, Lajos ,  SZALAY, Dániel ,  TAKATS, Zoltan

IPC分类号： G01N33/68 ,  A61B17/00 ,  G01N3/00 ,  G01N9/00 ,  H01J49/00 ,  A61B18/00 ,  G01N27/62

摘要： A method is disclosed comprising obtaining or acquiring image or other data from one or more regions of a target (2) using an imaging sensor (20). The image or other data may then be used to determine one or more regions of interest of the target (2). An ambient ionisation ion source (1) may then be used to generate aerosol, smoke or vapour (5) from one or more regions of the target (2).

公开(公告)号：EP3570315A2

公开(公告)日：2019-11-20

申请号：EP19171058.1

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： SIMON, Dániel ,  BALOG, Júlia ,  MACINTYRE, David ,  PRINGLE, Steven Derek ,  KARANCSI, Tamás ,  MORRIS, Michael Raymond ,  JONES, Emrys ,  LANGRIDGE, James Ian ,  BENNETT, Phillip ,  PRUSKI, Pamela ,  SZALAY, Dániel ,  TAKÁTS, Zoltán ,  GÖDÖRHÁZY, Lajos

IPC分类号： H01J49/04 ,  H01J49/00 ,  G01N27/62

摘要： A mass and/or ion mobility spectrometry method is disclosed comprising providing a biopsy sample; generating first analyte ions from a first position on said biopsy sample at a first time, and generating second analyte ions from a second different position on said biopsy sample at a second different time; and analysing said analyte ions.

公开(公告)号：EP3570315A3

公开(公告)日：2019-12-18

申请号：EP19171058.1

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： SIMON, Dániel ,  BALOG, Júlia ,  MACINTYRE, David ,  PRINGLE, Steven Derek ,  KARANCSI, Tamás ,  MORRIS, Michael Raymond ,  JONES, Emrys ,  LANGRIDGE, James Ian ,  BENNETT, Phillip ,  PRUSKI, Pamela ,  SZALAY, Dániel ,  TAKÁTS, Zoltán ,  GÖDÖRHÁZY, Lajos

IPC分类号： H01J49/04 ,  H01J49/00 ,  G01N27/62

摘要： A mass and/or ion mobility spectrometry method is disclosed comprising providing a biopsy sample; generating first analyte ions from a first position on said biopsy sample at a first time, and generating second analyte ions from a second different position on said biopsy sample at a second different time; and analysing said analyte ions.

公开(公告)号：EP3265819A1

公开(公告)日：2018-01-10

申请号：EP16710786.1

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： PRINGLE, Steven Derek ,  JONES, Emrys ,  MORRIS, Michael Raymond ,  BALOG, Júlia ,  LANGRIDGE, James Ian ,  RICHARDSON, Keith ,  SIMON, Dániel ,  GÖDÖRHÁZY, Lajos ,  SZALAY, Dániel ,  TAKÁTS, Zoltán

IPC分类号： G01N33/68 ,  A61B17/00 ,  G01N3/00 ,  G01N9/00 ,  H01J49/00 ,  A61B18/00 ,  G01N27/62

CPC分类号： H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/18 ,  G06F19/324 ,  G06F19/3481 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

摘要： A method is disclosed comprising obtaining or acquiring chemical or other non-mass spectrometric data from one or more regions of a target using a chemical sensor. The chemical or other non-mass spectrometric data may be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.

公开(公告)号：EP3265797A1

公开(公告)日：2018-01-10

申请号：EP16710791.1

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： TAKÁTS, Zoltán ,  BALOG, Júlia ,  PRINGLE, Steven Derek ,  KARANCSI, Tamás ,  MORRIS, Michael Raymond ,  GÖDÖRHÁZY, Lajos ,  SZALAY, Dániel ,  SIMON, Dániel

IPC分类号： G01N27/62 ,  H01J49/00 ,  G01N33/92 ,  G01N33/68 ,  G01N3/00 ,  G01N9/00 ,  A61B10/02 ,  A61B17/00 ,  A61B18/00 ,  A61B18/14

CPC分类号： H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/18 ,  G06F19/324 ,  G06F19/3481 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

摘要： An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.

公开(公告)号：EP3800657A1

公开(公告)日：2021-04-07

申请号：EP20210062.4

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： SIMON, Dániel ,  BALOG, Júlia ,  MACINTYRE, David ,  PRINGLE, Steven Derek ,  KARANCSI, Tamás ,  MORRIS, Michael Raymond ,  JONES, Emrys ,  LANGRIDGE, James Ian ,  BENNETT, Phillip ,  PRUSKI, Pamela ,  SZALAY, Dániel ,  TAKÁTS, Zoltán ,  GÖDÖRHÁZY, Lajos

IPC分类号： H01J49/14 ,  G01N33/68 ,  G01N1/02

摘要： A method is disclosed comprising providing a biological sample on a swab 900, directing a spray of charged droplets onto a surface of the swab 900 in order to generate a plurality of analyte ions, and analysing the analyte ions.

公开(公告)号：EP3741303A2

公开(公告)日：2020-11-25

申请号：EP20181905.9

申请日：2016-03-07

申请人： Micromass UK Limited

发明人： PRINGLE, Steven Derek ,  JONES, Emrys ,  MORRIS, Michael Raymond ,  BALOG, Júlia ,  LANGRIDGE, James Ian ,  RICHARDSON, Keith George ,  SIMON, Dániel ,  GODORHAZY, Lajos ,  SZALAY, Dániel ,  TAKATS, Zoltan

IPC分类号： A61B10/00 ,  G01N33/00 ,  H01J49/00

摘要： A method is disclosed comprising obtaining or acquiring chemical or other non-mass spectrometric data from one or more regions of a target 2 using a chemical sensor 20. The chemical or other non-mass spectrometric data may be used to determine one or more regions of interest of the target 2. An ambient ionisation ion source 1 may then be used to generate aerosol, smoke or vapour 5 from one or more regions of the target 2.